birkhäuser basel birkhäuser basel dez 2004 (10 risultati)

Taschenbuch. Condizione: Neu. Neuware -1. 1 Background In this work, we develop a framework for the design of multi-agent systems inspired by (human) organizational principles. Organizations are complex entities formed to ov- come various limitations of individual agencies, such as cognitive, physical, temporal and institutional limitations. There is a parallel between the complexity of organizations and multi-agent systems. Therefore, we explore the use of concepts, methods and techniques from human organizational design as architectural principles for multi-agent systems. Three research lines are presented: organizational modeling and coordination, interop- ability and agent models. Organizational modeling and coordination are concerned with how resources (i. e. agents) can be identi ed and related to each other. In order to have agents cooperate, several issues of interoperability have to be addressed. Agent models deal with the design of individual intelligent software agents, taking into account typical features of agent intelligence. Every (human) activity raises two challenges: division of labor and coordi- tion [Mintzberg, 1993]. Division of labor is the decomposition of work (or goals) into various distinct tasks. Coordination refers to managing relations between these tasks to carry out the work. The patterns of division of labor, responsibilities (people who do the work), clustering of responsibilities into units and coordination between units can be de ned by organizational structures [Galbraith, 1973]. The design of an organization should cover how one or more actors are engaged in one or more tasks, where knowledge, capabilities and resources are distributed.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 220 pp. Englisch.

Buch. Condizione: Neu. Neuware -Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2). Inour view, this book is especially timely. We are at the dawn of a revolution in the management of RA and other complex immunological inflammatory disorders because their molecular, genetic and environmental mechanisms are being unrav elled. Inthe process, we are revealing a substantial number of novel and significant targets for pharmacotherapy.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Englisch.

Buch. Condizione: Neu. Neuware -Alcoholism is a pathological behavioural syndrome, characterised by comp- sive alcohol use, craving and relapses, even recurring after many years of abstinence. It is suggested that chronic alcohol abuse leads to persistent changes within several neurochemical pathways in the brain and furthermore that an imprinted drug and addiction memory may scarcely be extinguished. Hence, the question arises as to whether there ought to be a reasonable hope that pharmacological drugs will be developed that interfere with an addiction memory, and as a result, finally lead to a cure In this book, leading preclinical and clinical experts in the field of alcohol relapse prevention strive to furnish an answer to this question. None of the researchers or clinicians believes in a magic bullet that will be of help to all alcoholic patients in overcoming this disease. However, there is now convi- ing evidence demonstrating that specific subpopulations of alcoholic patients experience satisfactory benefit from currently available treatments. Today we have two medications for relapse prevention on the market ¿ acamprosate and naltrexone. Although, currently, only a minority of alcoholic patients benefit from these medications, the approval of these compounds may be considered a hallmark in the field of psychopharmacology, even comparable to the era when the first antidepressant compounds were introduced. In recent years we have been witnessing an enormous growth in the science and knowledge regarding the field of relapse prevention.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Kolmogorov Equations for Stochastic PDEs gives an introduction to stochastic partial differential equations, such as reaction-diffusion, Burgers and 2D Navier-Stokes equations, perturbed by noise. It studies several properties of corresponding transition semigroups, such as Feller and strong Feller properties, irreducibility, existence and uniqueness of invariant measures. In addition, the transition semigroups are interpreted as generalized solutions of Kologorov equations. 182 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1. 1 Background In this work, we develop a framework for the design of multi-agent systems inspired by (human) organizational principles. Organizations are complex entities formed to ov- come various limitations of individual agencies, such as cognitive, physical, temporal and institutional limitations. There is a parallel between the complexity of organizations and multi-agent systems. Therefore, we explore the use of concepts, methods and techniques from human organizational design as architectural principles for multi-agent systems. Three research lines are presented: organizational modeling and coordination, interop- ability and agent models. Organizational modeling and coordination are concerned with how resources (i. e. agents) can be identi ed and related to each other. In order to have agents cooperate, several issues of interoperability have to be addressed. Agent models deal with the design of individual intelligent software agents, taking into account typical features of agent intelligence. Every (human) activity raises two challenges: division of labor and coordi- tion [Mintzberg, 1993]. Division of labor is the decomposition of work (or goals) into various distinct tasks. Coordination refers to managing relations between these tasks to carry out the work. The patterns of division of labor, responsibilities (people who do the work), clustering of responsibilities into units and coordination between units can be de ned by organizational structures [Galbraith, 1973]. The design of an organization should cover how one or more actors are engaged in one or more tasks, where knowledge, capabilities and resources are distributed. 204 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Kolmogorov Equations for Stochastic PDEs gives an introduction to stochastic partial differential equations, such as reaction-diffusion, Burgers and 2D Navier-Stokes equations, perturbed by noise. It studies several properties of corresponding transition semigroups, such as Feller and strong Feller properties, irreducibility, existence and uniqueness of invariant measures. In addition, the transition semigroups are interpreted as generalized solutions of Kologorov equations.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 196 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Alcoholism is a pathological behavioural syndrome, characterised by comp- sive alcohol use, craving and relapses, even recurring after many years of abstinence. It is suggested that chronic alcohol abuse leads to persistent changes within several neurochemical pathways in the brain and furthermore that an imprinted drug and addiction memory may scarcely be extinguished. Hence, the question arises as to whether there ought to be a reasonable hope that pharmacological drugs will be developed that interfere with an addiction memory, and as a result, finally lead to a cure In this book, leading preclinical and clinical experts in the field of alcohol relapse prevention strive to furnish an answer to this question. None of the researchers or clinicians believes in a magic bullet that will be of help to all alcoholic patients in overcoming this disease. However, there is now convi- ing evidence demonstrating that specific subpopulations of alcoholic patients experience satisfactory benefit from currently available treatments. Today we have two medications for relapse prevention on the market - acamprosate and naltrexone. Although, currently, only a minority of alcoholic patients benefit from these medications, the approval of these compounds may be considered a hallmark in the field of psychopharmacology, even comparable to the era when the first antidepressant compounds were introduced. In recent years we have been witnessing an enormous growth in the science and knowledge regarding the field of relapse prevention. 256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Gentechnisch hergestellte Produkte werden heute bereits in der Medizin und der Diagnostik, in den Agrarwissenschaften, in der Lebensmitteltechnologie aber auch in zahlreichen Bereichen des täglichen Lebens verwendet. Seit der Einführung des ersten gentechnisch hergestellten Medikamentes im Jahr 1983 hat sich die Gentechnik in rasanter Weise zu einer Schlüsseltechnologie in der Grundlagenforschung, der angewandten Forschung und der Wirtschaft entwickelt.Die Gentechnik, ihre Vorteile und ihre möglichen Risiken, werden heute in der Öffentlichkeit und in den Medien sehr breit und mit viel Engagement diskutiert. Trotz allen Interesses an diesem Thema zeigt es sich immer wieder, dass die Gentechnik in ihren Grundzügen oft nur unvollständig bekannt und verstanden ist.Auch die 3. erweiterte und überarbeitete Auflage dieses erfolgreichen Buches bietet kurz und knapp, im Detail und anschaulich illustriert einen verständlichen Einblick in die Theorie und Praxis der Materie. Hochaktuelle Themen wie Stammzellen in Forschung und Therapie, 'Elegante Züchtung' bei transgenen Pflanzen, Sequenzierungsmeilensteine oder Einführungen in Begriffe wie Genomics und Proteomics sind neu hinzugekommen. Durch das Buch wird der Leser vor allem die vielfältigen Verflechtungen zwischen Theorie und Anwendung der Gentechnik erkennen und beurteilen können. Diese neue Auflage soll einen wichtigen Beitrag dazu leisten, dass die Diskussion über Gentechnik um Sachinhalte und nicht um Ideologien geführt wird. 176 pp. Deutsch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Gentechnisch hergestellte Produkte werden heute bereits in der Medizin und der Diagnostik, in den Agrarwissenschaften, in der Lebensmitteltechnologie aber auch in zahlreichen Bereichen des täglichen Lebens verwendet.Seit der Einführung des ersten gentechnisch hergestellten Medikamentes im Jahr 1983 hat sich die Gentechnik in rasanter Weise zu einer Schlüsseltechnologie in der Grundlagenforschung, der angewandten Forschung und der Wirtschaft entwickelt.Die Gentechnik, ihre Vorteile und ihre möglichen Risiken, werden heute in der Öffentlichkeit und in den Medien sehr breit und mit viel Engagement diskutiert.Trotz allen Interesses an diesem Thema zeigt es sich immer wieder, dass die Gentechnik in ihren Grundzügen oft nur unvollständig bekannt und verstanden ist.Auch die 3. erweiterte und überarbeitete Auflage dieses erfolgreichen Buches bietet kurz und knapp, im Detail und anschaulich illustriert einen verständlichen Einblick in die Theorie und Praxis der Materie. Hochaktuelle Themen wie Stammzellen in Forschung und Therapie, 'Elegante Züchtung' bei transgenen Pflanzen, Sequenzierungsmeilensteine oder Einführungen in Begriffe wie Genomics und Proteomics sind neu hinzugekommen. Durch das Buch wird der Leser vor allem die vielfältigen Verflechtungen zwischen Theorie und Anwendung der Gentechnik erkennen und beurteilen können.Diese neue Auflage soll einen wichtigen Beitrag dazu leisten, dass die Diskussion über Gentechnik um Sachinhalte und nicht um Ideologien geführt wird.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 176 pp. Deutsch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2). Inour view, this book is especially timely. We are at the dawn of a revolution in the management of RA and other complex immunological inflammatory disorders because their molecular, genetic and environmental mechanisms are being unrav elled. Inthe process, we are revealing a substantial number of novel and significant targets for pharmacotherapy. 343 pp. Englisch.