Birkhäuser basel okt 2012 (290 risultati)

Taschenbuch. Condizione: Neu. Neuware - 'Extremely readable recollections of the author. A rare testimony of a period of the history of 20th century mathematics. Includes very interesting recollections on the author's participation in the formation of the Bourbaki Group, tells of his meetings and conversations with leading mathematicians, reflects his views on mathematics. The book describes an extraordinary career of an exceptional man and mathematicians. Strongly recommended to specialists as well as to the general public.'EMS Newsletter (1992)'This excellent book is the English edition of the author's autobiography. . This very enjoyable reading is recommended to all mathematicians.'Acta Scientiarum Mathematicarum (1992).…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Fractals in Biology and Medicine' explores the potential of fractal geometry for describing and understanding biological organisms, their development and growth as well as their structural design and functional properties. It extends these notions to assess changes associated with disease in the hope to contribute to the understanding of pathogenetic processes in medicine. The book is the first comprehensive presentation of the importance of the new concept of fractal geometry for biological and medical sciences. It collates in a logical sequence extended papers based on invited lectures and free communications presented at a symposium in Ascona, Switzerland, attended by leading scientists in this field, among them the originator of fractal geometry, Benoit Mandelbrot. 'Fractals in Biology and Medicine' begins by asking how the theoretical construct of fractal geometry can be applied to biomedical sciences and then addresses the role of fractals in the design and morphogenesis of biological organisms as well as in molecular and cell biology. The consideration of fractal structure in understanding metabolic functions and pathological changes is a particularly promising avenue for future research. 397 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the key concerns in modern control theory is the design of steering strategies. The implementation of such strategies is done by a regulator. Presented here is a self-contained introduction to the mathematical background of this type of regulator design. The topics selected address the matter of greatest interest to the control community, at present, namely, when the design objective is the reduction of the influence of exogeneous disturbances upon the output of the system. In a first scenario the disturbance signal is regarded as a deterministic time series with known dynamics but unknown parameters. The design objective is then the asymptotic disturbance compensation. In a second scenario, no information about the disturbance signal is available apart from some bounds. Here, in an H-approach, control strategies are worked out which will prove efficient for all such disturbances. The intention of this book is to present ideas and methods on such a level that the beginning graduate student will be able to follow current research. New results are included, especially for nonlinear control systems, and as a service to the reader, an extensive appendix presents topics from linear algebra, invariant manifolds and calculus of variations, information which is hardly to be found in standard textbooks. Contents: Introduction - The problem of output regulation - Introduction - Problem statement - Output regulation via full information - Output regulation via full error feedback - A particular case - Well-posedness and robustness - The construction of a robust regulator - Disturbance attenuation via H-methods - Introduction - Problem statement - A characterization of the L2-gain of a linear system - Disturbance attenuation via full information - Disturbance attenuation via measured feedback - Full information regulators - Problem statement - Time-dependent control strategies - Examples - Time-independent control strategies- The local case - Nonlinear observers - Problem statement - Time-dependent observers - Error feedback regulators - Examples - Nonlinear H-techniques - Introduction - Construction of the saddle-point - The local scenario - Disturbance attenuation via linearization - Matrix equations - Linear matrix equations - Algebraic Riccati equations - Invariant manifolds - Existence theorem - Outflowing manifolds - Asymptotic phase - Convergence for T - A special case - Dichotomies and Lyapunov functions - Hamilton-Jacobi-Bellman-Isaacs equation - Introduction - Method of characteristics - The equation of Isaacs - The Hamiltonian version of Isaacs' equation - Bibliography 168 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The controversy between the wave theory and the emission theory of light early in the nineteenth century has been a subject of numerous studies. Yet many is sues remain unclear, in particular, the reasons for rejecting Young's theory of light. It appears that further progress in the field requires a better grasp of the overall situation in optics and related subjects at the time and a more thorough study of every factor suggested to be of importance for the dispute. This book is intended to be a step in this direction. It examines the impact of the concept of interference of light on the development of the early nineteenth century optics in general, and the theory of light, in particular. This is not a his tory of the wave theory of light, nor is it a history of the debate on the nature of light in general: it covers only that part of the controversy which involved the concept of interference. Although the book deals with a number of scientists, scientific institutions, and journals, its main character is a scientific concept, the principle of interference. While discussing the reasons for accepting or rejecting this concept I have primarily focused on scientific factors, although in some cases the human factor is examined as well. The book is a revised Ph. D. dissertation (University of Minnesota, 1984) writ ten under Alan E. Shapiro. 271 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A collection of papers by international contributors describing new developments in the fields of univariate and multivariate approximation theory. This research has applications in areas such as computer-aided geometric design, as applied in engineering and medical technology (e.g. computerized tomography). 348 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The accumulation of white blood cells is a hallmark of inflammation. The penetra tion through the vessel walls and the infiltration around the inflammatory stimulus is a complex process which involves active adherence and directed migration of the inflammatory cells. Chemotactic factors stimulate both adherence and migration. Technical tools such as the Boyden chamber [1] made it possible to study leukocyte migration in vitro. This technique allows differentiation between migration direct ed towards a chemotactic stimulus and non-directed migration. Until a decade ago only two naturally occurring molecules had been clearly iden tified as potent chemotactic attractants of neutrophilic granulocytes. They were the split product of the fifth complement component C5a [2] and the arachidonic acid metabolite leukotriene B4 [3]. In 1986, a novel human monocyte-derived chemo taxin attracting neutrophilic granulocytes with a similar potency was found [4]. This report was quickly confirmed by several groups [5-8]. The new factor was purified, cloned and sequenced [9, 10]. The term 'interleukin 8' (IL-8) replaced the various names proposed previously [4-8]. Sequence data revealed that IL-8 belonged to a large family of chemotactic cytokines, now called 'chemokines' [11]. Four subfamilies were distinguished on the basis of the number and position of the first cysteine residues. They are desig nated accordingly as C, CC, CXC and CX C chemokines [11-13]. The number of 3 human chemokines identified so far is close to 40 [11-13]. 156 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the original proof of Gromov's compactness theorem for pseudo-holomorphic curves in detail. Local properties of pseudo-holomorphic curves are investigated and proved from a geometric viewpoint. Properties of particular interest are isoperimetric inequalities, a monotonicity formula, gradient bounds and the removal of singularities. 148 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Award-winning monograph of the Ferran Sunyer i Balaguer Prize 2002.The subject of this book is the study of automorphic distributions, by which is meant distributions on R 2 invariant under the linear action of SL(2,Z), and of the operators associated with such distributions under the Weyl rule of symbolic calculus. Researchers and postgraduates interested in pseudodifferential analyis, the theory of non-holomorphic modular forms, and symbolic calculi will benefit from the clear exposition and new results and insights. 260 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When this book was first published (in Russian), it proved to become the fountainhead of a major stream of important papers in mathematics, physics and even chemistry; indeed, it formed the basis of new methodology and opened new directions for research. The present English edition includes new examples of applications to physics, hitherto unpublished or available only in Russian. Its central mathematical idea is to use topological methods to analyze isotropic invariant manifolds in order to obtain asymptotic series of eigenvalues and eigenvectors for the multi-dimensional Schrödinger equation, and also to take into account the so-called tunnel effects. Finite-dimensional linear theory is reviewed in detail. Infinite-dimensional linear theory and its applications to quantum statistics and quantum field theory, as well as the nonlinear theory (involving instantons), will be considered in a second volume. 304 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Award-winning monograph of the Ferran Sunyer i Balaguer Prize 1997.This book is a self-contained exposition of the spectral theory of Toeplitz operators with piecewise continuous symbols and singular integral operators with piecewise continuous coefficients. It includes an introduction to Carleson curves, Muckenhoupt weights, weighted norm inequalities, local principles, Wiener-Hopf factorization, and Banach algebras generated by idempotents. Some basic phenomena in the field and the techniques for treating them came to be understood only in recent years and are comprehensively presented here for the first time.The material has been polished in an effort to make advanced topics accessible to a broad readership. The book is addressed to a wide audience of students and mathematicians interested in real and complex analysis, functional analysis and operator theory. 420 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In modern ecotoxicology, fish have become the major vertebrate model, and a tremendous body of information has been accumulated. This volume attempts to summarize our present knowledge in several fields of primary ecotoxicological interest ranging from the use of (ultra)structural modifications of selected cell systems as sources of biomarkers for environmental impact over novel approaches to monitoring the impact of xenobiotics with fish in vitro systems such as primary and permanent fish cell cultures, the importance of early life-stage tests with fish, the bioaccumulation of xenobiotics in fish, the origin of liver neoplastic lesions in small fish species, immunocytochemical approaches to monitoring effects in cytochrome P450-related biotransformation, the impact of heavy metals in soft water systems, the environmental toxicology of organotin compounds, oxidative stress in fish by environmental pollutants to effects by estrogenic substances in aquatic systems. 412 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book gives a complete global geometric description of the motion of the two di mensional hannonic oscillator, the Kepler problem, the Euler top, the spherical pendulum and the Lagrange top. These classical integrable Hamiltonian systems one sees treated in almost every physics book on classical mechanics. So why is this book necessary The answer is that the standard treatments are not complete. For instance in physics books one cannot see the monodromy in the spherical pendulum from its explicit solution in terms of elliptic functions nor can one read off from the explicit solution the fact that a tennis racket makes a near half twist when it is tossed so as to spin nearly about its intermediate axis. Modem mathematics books on mechanics do not use the symplectic geometric tools they develop to treat the qualitative features of these problems either. One reason for this is that their basic tool for removing symmetries of Hamiltonian systems, called regular reduction, is not general enough to handle removal of the symmetries which occur in the spherical pendulum or in the Lagrange top. For these symmetries one needs singular reduction. Another reason is that the obstructions to making local action angle coordinates global such as monodromy were not known when these works were written. 456 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Eighth International Conference of the Inflammation Research Association was held on October 27 to 31, 1996 at Hershey Lodge and Convention Center in Hershey, Pennsylvania. As have others in this series, the conference focused on understanding the molecular mechanisms involved in acute and chronic inflammatory reactions as well as on therapeutic approaches to treating inflammatory diseases. One outstanding symposium focused on new drugs and was de signed as a forum for the dissemination of early clinical results on new anti-inflammatory agents. Other symposia spotlighted exciting advances being made in defining intracellular signaling path ways and the potential for future therapeutics that target cytokines and costimulatory pathways. This conference was characterized by a high level of participation by attendees, who represent both the academic and industrial sectors. It was gratifying to note that a large proportion of the attending scientists presented their latest findings during workshops, poster discussions, and pos ter se.ssions. This volume covers many of the highlights of the Eighth International Conference and should become a valuable resource for scientists involved in inflammation research and drug discovery. 124 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As in so many fields of scientific endeavour following the molecular biology revo lution, our knowledge of the role of radicals not only in pathological states, but in basic physiology has developed exponentially. Indeed, our evolving concepts have, like so many political parties, been forced into dramatic 'V-turns' and contortions. Within our working lives, we have had to debate whether radicals made any con tribution to any pathology, whilst now it is difficult not to entertain the view that every physiological process is pivotally controlled by exquisitely sensitive radical reactions. Inflammation is, of course, an example of pathology evolving from physiology, and in this book we have called upon both scientists and clinicians who have research interests in the complex switching mechanisms that sustain these transi tions. The book as a whole explores, from a physiological standpoint, how deter ministic radical systems sensitive to their initial conditions can interdigitate, iterate and feed back to control diverse cellular processes that create the inflammatory response. Whilst systems such as these to a mathematician would provide the basis for a chaotic response, one is forced to marvel how, for all stages of an inflammatory reaction, this system appears exquisitely controlled, making therapeutic manipula tion both possible and, to some extent, predictable. 276 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cytokines have become established as key mediators of the signs andsymptoms of inflammatory diseases such as arthritis, dermatitis, asthmaand multiple sclerosis. Furthermore, they are involved in the cascade ofevents leading to cardiovascular shock and are major regulators of thefunction of immune cells.This book reviews recent advances in the development of newanti-inflammatory drugs. It addresses different therapeutic interventionpossibilities for new drugs, such as the cellular source of cytokines,specific receptors which induce cytokine synthesis, intracellularregulators of cytokine gene induction and expression, secretion andactivation of cytokines, cytokine receptors and signalling pathways fromthese receptors. Accordingly, experts were drawn from differentbackgrounds including academic research institutes, the pharmaceuticalindustry and clinical pharmacology. In each area, the opportunities fordrug development are highlighted and, where possible, clinical data isreviewed. 284 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1920s, a long-lasting controversy on the interpretation of nuclear beta spectrum arose between Lise Meitner and Charles Drummond Ellis. This controversy, and the reactions from the contending parties when it was settled, reflect clearly the difference between the scientific communities in Berlin and Cambridge at that time. The Meitner-Ellis controversy ended in 1929, and it left an anomaly that attracted leading theoretical physicists. A new dispute, this time between Niels Bohr and Wolfgang Pauli, broke out. It concerned the explanation of the continuity of the primary beta particles and dominated the discussions for the next five years. Pauli argued for a new particle, and Bohr for a new theory; both suggestions were radical steps, but they reflected two different ways of doing physics. 240 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the fortuitous discovery of its anticonvulsant activIty in 1962, valproate has established itself worldwide as a major antiepileptic drug against several types of epileptic seizures. Clinical experience with valpro ate has continued to grow in recent years, including use of valproate for diseases other than epilepsy, for example in bipolar disorders and migraine. In this volume on valproate emphasis is placed on the scientific back ground leading to the discovery of val pro ate, its subsequent pharmacologi cal and toxicological characterization, and its clinical development into one of the most widely and successfully used anti epileptic drugs, a real mile stone in drug therapy. The current state of knowledge of valproate will be reviewed by experts in the field, including new hypotheses about its mecha nisms of action, its metabolism into pharmacologically active metabolites, its unique distribution characteristics, its unwanted hepatotoxic and terato genic adverse effects and its various clinical uses. Furthermore, the wide variety of available pharmaceutical formulations of valproate, including novel controlled-release formulations, will be outlined. The monograph is aimed at a broad readership, particularly neurologists, psychiatrists and basic scientists working in the field of epilepsy research. Because the monograph also deals with structure-activity relationships of valproate as well as of its metabolites and analogs, the book should also serve for rese archers working in medicinal chemistry, particularly in the pharmaceutical industry. 308 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is dedicated to our teacher and friend Hans Triebel. The core of the book is based on lectures given at the International Conference 'Function Spaces, Differential Operators and Nonlinear Analysis' (FSDONA--01) held in Teistungen, Thuringia / Germany, from June 28 to July 4,2001, in honour of his 65th birthday. This was the fifth in a series of meetings organised under the same name by scientists from Finland (Helsinki, Oulu) , the Czech Republic (Prague, Plzen) and Germany (Jena) promoting the collaboration of specialists in East and West, working in these fields. This conference was a very special event because it celebrated Hans Triebel's extraordinary impact on mathematical analysis. The development of the mod ern theory of function spaces in the last 30 years and its application to various branches in both pure and applied mathematics is deeply influenced by his lasting contributions. In a series of books Hans Triebel has given systematic treatments of the theory of function spaces from different points of view, thus revealing its interdependence with interpolation theory, harmonic analysis, partial differential equations, nonlinear operators, entropy, spectral theory and, most recently, anal ysis on fractals. The presented collection of papers is a tribute to Hans Triebel's distinguished work. The book is subdivided into three parts: - Part I contains the two invited lectures by O.V. Besov (Moscow) and D.E. Edmunds (Sussex) having a survey character and honouring Hans Triebel's contributions. 492 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is about discrete-time, time-homogeneous, Markov chains (Mes) and their ergodic behavior. To this end, most of the material is in fact about stable Mes, by which we mean Mes that admit an invariant probability measure. To state this more precisely and give an overview of the questions we shall be dealing with, we will first introduce some notation and terminology. Let (X,B) be a measurable space, and consider a X-valued Markov chain ~. = {~k' k = 0, 1, . } with transition probability function (t.pJ.) P(x, B), i.e., P(x, B) := Prob (~k+1 E B I ~k = x) for each x E X, B E B, and k = 0,1, . The Me ~. is said to be stable if there exists a probability measure (p.m.) /.l on B such that (\*) VB EB. /.l(B) = Ix /.l(dx) P(x, B) If (\*) holds then /.l is called an invariant p.m. for the Me ~. (or the t.p.f. P). 228 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Methods in Pulmonary Research' presents a comprehensive review of methods used to study physiology and the cell biology of the lung. The book covers the entire range of techniques from those that require cell cultures to those using in vivo experimental models. Up-to-date techniques such as intravital microscopy are presented. Yet standard methods such as classical short circuit techniques used to study tracheal transport are fully covered. This book will be extremely useful for all who work in pulmonary research, yet need a practical guide to incorporate other established methods into their research programs. Thus the book will prove to be a valuable resource for cell biologists who wish to use organs in their research programs as well biological scientists who are moving their research programs into more cell related phenomena. 572 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In step with our growing lifespan, dementia is becoming a widespreadhandicap to the health and well-being of individuals and a burden onhuman society world-wide. The increasing prevalence of this tragiccondition has stimulated an explosion of scientific research in the lastten years, which resulted in numerous profound insights and technicalinnovations. This timely volume presents both an overall and a detailedoverview of the current worldwide knowledge about the neuroscientificbasis of dementia.Leading authorities in their fields provide a far-reaching synthesis ofall topics in dementia research, including pathogenesis of dementia,neuroimaging of the earliest alterations, potential biological andgenetic markers for Alzheimer`s Disease and new therapeutic strategies.Each chapter discusses clinical implications and areas of controversy,highlights the wide range of current and future therapeuticpossibilities and indicates promising directions for further research. 324 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nitric oxide is an endogenously produced gas with a wide range of biological effects and has been implicated in many physiological and pathophysiological processes. It is released by many cell types in various organs but is particularly important in the maintenance of normal lung function. Nitric oxide in exhaled breath has been identified as a marker for lung disease in some patients. Thus, it is appropriate to consider the lung separately for the role and functioning of nitric oxide. The authors identify key areas in the history, biochemistry, physiology, pathophysiology, immunology and clinical applications of nitric oxide in the lung. The contents of this book will be of particular importance to scientists and clinicians with an interest in lung disease. Moreover, the authors encompass state of the art opinions of and rational for the therapeutic potential of nitric oxide and its inhibitors. 244 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although surprising, it seems fitting that a drug developed at the dawn of the era of rational drug design and therapeutics, methotrexate, should remain in common use for the therapy of so many different kinds of illnesses. Moreover, methotrexate has completely revolutionized the way in which medicine is practiced in a number of speciality areas. First developed to treat malignancies, methotrexate is now commonly used to treat gynecological problems, inflammatory arthritis, skin disease and probably other ailments as well. This work is designed to give a broad overview of the history of methotrexate's development, its prior use and its current therapeutic uses. As discussed in Chapter I, aminopterin and methotrexate were designed to inhibit mammalian folate metabolism but the concept of folic acid antag onism was soon applied to the development of antibacterial and anti parasitic agents. Trimethoprim and sulfa drugs were among the first antibiotics developed and they also remain quite useful today for the treat ment of a variety of infections. 152 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the refereed proceedings of the Workshop on Cryptography and Computational Number Theory, CCNT'99, which has been held in Singapore during the week of November 22-26, 1999. The workshop was organized by the Centre for Systems Security of the Na tional University of Singapore. We gratefully acknowledge the financial support from the Singapore National Science and Technology Board under the grant num ber RP960668/M. The idea for this workshop grew out of the recognition of the recent, rapid development in various areas of cryptography and computational number the ory. The event followed the concept of the research programs at such well-known research institutions as the Newton Institute (UK), Oberwolfach and Dagstuhl (Germany), and Luminy (France). Accordingly, there were only invited lectures at the workshop with plenty of time for informal discussions. It was hoped and successfully achieved that the meeting would encourage and stimulate further research in information and computer security as well as in the design and implementation of number theoretic cryptosystems and other related areas. Another goal of the meeting was to stimulate collaboration and more active interaction between mathematicians, computer scientists, practical cryptographers and engineers in academia, industry and government. 392 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Radioactive Isotopes in Clinical Medicine and Research XXIII presents an update in the latest clinical research in nuclear medicine. It provides in-depth information on all areas of nuclear medicine. The chapters of this volume have been grouped into the following sections: Neurology / Psychiatry, Therapy, Radiopharmacology, Endocrinology / Thyroid, Oncology / Haematology, Clinical PET, Cardiology, Varia, Physics / Radiation Protection, World Wide Web / WWW demo. Special attention is paid to the virtual media for teaching, training, communication, quality control etc. Primarily intended for specialists in the nuclear medicine, this volume will also be of considerable interest to clinicians using diagnostic and therapeutic nuclear medicine procedures, including cardiologists, haematologists, neurologists, nephrologists, oncologists, pharmacologists, and psychiatrists. 596 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -What are the different muscarinic acetylcholine receptor subtypes andhow are they distributed in the airways and molecular signallingmechanisms What is their function in neurogenic and non-neurogeniccontrol of the airways and in inflammatory mechanisms How is their geneexpression regulated The great importance of muscarinic acetylcholinereceptors for the pathophysiology and treatment of chronic inflammatoryobstructive airways diseases calls for a comprehensive and integratedoverview of the current knowledge to address such questions, to discussthe role of these receptor subtypes in diseases such as asthma and COPD,and to present novel perspectives on antimuscarinic drug development.The present book is the worthy result of this need. It points outinnovative insights into the hitherto poorly understood role ofpostjunctional muscarinic M2 receptors in airway smooth musclecontraction and sheds some light on the novel concepts of antimuscarinicdrug development, with special reference to the l 284 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Discrete stochastics is the theory of discrete probability spaces. This undergraduate textbook gives a concise introduction into discrete stochastics in general, and into a variety of typical special topics in this field, such as information theory, fluctuation theory, and semigroups of stochastic matrices. The emphasis lies on probability theory rather than on statistical methodology. Motivations, interpretations, and numerous examples and exercises relate the mathematical theory to stochastic experience. 296 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This meeting has been motivated by two events: the 85th birthday of Pierre Lelong, and the end of the third year of the European network 'Complex analysis and analytic geometry' from the programme Human Capital and Mobility. For the first event, Mathematicians from Poland, Sweden, United States and France, whose work is particularly related to the one ofP. Lelong have accepted to participate; for the second, the different teams of the Network sent lecturers to report on their most recent works. These teams are from Grenoble, Wuppertal, Berlin, Pisa and Paris VI; in fact, most of their results are also related to Lelong's work and, a posteriori, it is difficult to decide whether a talk is motivated by the first or by the second event. We chose only plenary lectures, usually of one hour, except a small number, given by young mathematicians, which have been shorter. A two hours problem session has been organized. The Proceedings gather papers which are exact texts of the talks, or are closely related to them. The members from the Network and five other lecturers sent us papers; the other lecturers published the content of their talks in mathematical Journals. All the presented texts have been submitted to referees independent of the organizing committee; the texts of the problems have been approved by their authors. 260 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume will be of great value to all those researchers in the area of the inflam matory response, notably academics, clinicians and members of the pharmaceutical industry. The book has in the main been restricted to three inducible enzymes, namely nitric oxide synthase (iNOS), cyclooxygenase (COX-2) and hemeoxygenase (HO-l), although matrix metalloproteinases, xanthine oxidoreductase and tissue transgluta minases are reviewed. The modulation of these enzymes is viewed as possible novel therapeutic advances in the area of inflammation and also cancer. The latter topic may well be the subject of a further book. It will be interesting to observe the progress of such new therapies in the next decade. Already some of these enzyme modulators have been approved for the treat ment of inflammatory disease, as evidenced by the new families of COX-2 inhibitors. We believe such advances will herald a series of new and exciting agents to be included in the clinician's armamentarium in the constant struggle against inflammatory disease. The editors wish to thank all contributors to this volume on inducible enzymes. It should however be stressed that the views expressed by the authors are personal and do not necessarily reflect those of the editors. Indeed, the reader may find con flicting statements in a number of the chapters. We believe that this is entirely appro priate as this volume reflects the latest work in a rapidly developing area. 228 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On the basis of the agreement signed between UNESCO and the Government of the Republic of Poland the International Institute for Cell and Molecular Biology of UNESCO was officially inaugurated in October 1995 in Warsaw, Poland, as part of the activity of the Global Network for Molecular and Cell Biology (MCBN) of UNESCO. The occasion was marked by the bringing together in Warsaw of a broad spectrum of cell and molecular biologists from around the world under the auspices of the Global MCBN UNESCO. At the conclusion of that week-long celebration it became clear that Polish cell and molecular biology had come of age in terms of its depth, vigor and impact on the global scene. At the suggestion of Professor Angelo Azzi, chairman of Global MCBN UNESCO, we considered the challenge of compiling a volume in the Molecular and Cell Biology Updates tMCBU) Series that would address the molecular basis of cancer and its therapy, but one that would additionally serve to highlight Polish contributions to this field of research. We accepted the challenge presented to us by Professor Azzi and are grateful to all contributors of the present volume for making this a pleasant and stimulating project. We requested each contributor to present his personal perspective of respective topics. As a consequence, we hope that each contribution has a distinctive individual flavor which reflects the role played by individual research groups in advancing science. 252 pp. Englisch.…