Crc press aug 2014 (22 risultati)

Taschenbuch. Condizione: Neu. Neuware - ' Once you are in medical school you will need to apply for Foundation training; once in Foundation training you will need to apply for core or specialty training; if you go through core training, you will need to apply for specialty training; and once in specialty training, you will need to apply for consultancy posts. Knowing about this allows you to prepare for the next application, and enables you to show yourself in the best light in the application process.The majority of medical careers are becoming increasingly competitive, with many specialties subject to competition ratios of over 10 applicants for each place.' David McGowan and Helen Sims ' This book provides an excellent and easy-to-read path to making the most of your medical career starting as a student.and a ready source of really useful hints and tips that will help anyone reading this book maximise their personal and professional development.' From the Foreword by Dr Inam Haq Want to optimise your chances of success Take a fresh look at the clinical world. Medical careers have changed and learning how to play the game is as important as being the best in your field. This inspirational new guide considers your medical career from a wide-ranging perspective, encouraging a positive, early outlook. On a highly practical note, it acts as a comprehensive information source, covering all aspects of job applications and medical careers. On a personal note the book fosters a complete reassessment of the way you view your working life. It offers fresh ideas to help identify important opportunities to improve your CV - taking opportunities when you can whilst making the most of what you have. Easy to read and conversational in tone, it details invaluable ideas on developing your portfolio and innovative methods to successfully market yourself, alongside sound approaches to the challenges and intricacies of the modern medical career.…

Buch. Condizione: Neu. Neuware - Tackle the Challenges of Parallel Programming in the Visual Effects IndustryIn Multithreading for Visual Effects, developers from DreamWorks Animation, Pixar, Side Effects, Intel, and AMD share their successes and failures in the messy real-world application area of production software. They provide practical advice on multithreading techniques and visual effects used in popular visual effects libraries (such as Bullet, OpenVDB, and OpenSubdiv), one of the industry's leading visual effects packages (Houdini), and proprietary animation systems. This information is valuable not just to those in the visual effects arena, but also to developers of high performance software looking to increase performance of their code.Diverse Solutions to Solve Performance Problems After an introductory chapter, each subsequent chapter presents a case study that illustrates how the authors used multithreading techniques to achieve better performance. The authors discuss the problems that occurred and explain how they solved them. The case studies encompass solutions for shaving milliseconds, solutions for optimizing longer running tasks, multithreading techniques for modern CPU architectures, and massive parallelism using GPUs. Some of the case studies include open source projects so you can try out these techniques for yourself and see how well they work.…

Buch. Condizione: Neu. Neuware - Every year the Swiss Commission for Flood Protection (KOHS) of the Swiss Association for Water Management (SWV) organizes a symposium where professionals, officers of public administrations, and researchers exchange their experiences on special topics and key projects in river engineering and restoration. In 2014, this symposium was organized as a special session of the seventh International Conference on Fluvial Hydraulics River Flow 2014 at cole Polytechnique F d rale de Lausanne (EPFL), Switzerland. In addition to the Swiss participants, scientists and professionals from all over the world were informed about Swiss competences in river engineering and restoration. The aim of the book is to enrich flood protection and river restoration projects all over the world.…

Taschenbuch. Condizione: Neu. Neuware - Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry.A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry.Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.…

Buch. Condizione: Neu. Neuware - Bridging the gap between the peripheral and central nervous systems, the second edition of Neuroanatomical Basis of Clinical Neurology enriches understanding of neurological conditions through a conceptual approach to neuronal circuitry. The book retains the basic outline of contents from the first edition, integrating structural organization with pertinent clinical disorders, while reflecting the substantial growth and ever-changing information in neuroscienceAfter an introduction to the developmental and cellular aspects of the nervous system, the book discusses in depth the morphology and internal organization of the central nervous system. It examines the somatic and autonomic components of the peripheral nervous system, emphasizing nerve entrapments and neuropathies. The author describes various dysfunctions by demonstrating the neuronal interconnectivity between higher and lower autonomic centers and the mediation of visceral reflexes.The Second Edition incorporates and highlights common and relevant clinical conditions. Topics include: - Various forms of cortical dysfunctions, such as seizures, disconnection syndrome, coma, and dementia - The role of prefrontal cortex in behavior and attention, introducing the topic of autism - Up-to-date information on the auditory, vestibular, gustatory, and limbic systems - The neurochemistry of the limbic system, memory and associated disorders, and the structural and neuronal circuitry of the hippocampal gyrus - Structural organization and associated pathways of the extrapyramidal system, demonstrating the neurochemical basis of movement disorders This new edition skillfully integrates over a decade of discovery in neuroscience since the publication of the first edition, and introduces deepened insights into the neuronal synaptic connectivity and the mechanisms that underlie neurologic disorders. The book remains an essential source of information for medical and allied health students, practitioners of neurology, and students of neuroscience.…

Buch. Condizione: Neu. Neuware - Actuarial Models: The Mathematics of Insurance, Second Edition thoroughly covers the basic models of insurance processes. It also presents the mathematical frameworks and methods used in actuarial modeling. This second edition provides an even smoother, more robust account of the main ideas and models, preparing students to take exams of the Society of Actuaries (SOA) and the Casualty Actuarial Society (CAS).New to the Second Edition - Revises all chapters, especially material on the surplus process - Takes into account new results and current trends in teaching actuarial modeling - Presents a new chapter on pension models - Includes new problems from the 2011-2013 CAS examinations Like its best-selling, widely adopted predecessor, this edition is designed for students, actuaries, mathematicians, and researchers interested in insurance processes and economic and social models. The author offers three clearly marked options for using the text. The first option includes the basic material for a one-semester undergraduate course, the second provides a more complete treatment ideal for a two-semester course or self-study, and the third covers more challenging topics suitable for graduate-level readers.…

Buch. Condizione: Neu. Neuware - The first photographic and descriptive musculoskeletal atlas of a baby gorilla, this book details the comparative and phylogenetic context of the gross anatomy and evolutionary history of the soft tissue morphology of modern humans and one of their closest relatives. With detailed high-quality photographs of musculoskeletal structures, it provides an updated review of the anatomical variations within gorillas as well as an extensive list of the synonyms used in the literature to designate the structures discussed. It will be of interest to students, teachers, and researchers studying primatology, comparative anatomy, functional morphology, zoology, and physical anthropology. …

Buch. Condizione: Neu. Neuware - With an ever-increasing amount of information on the web, it is critical to understand the pedigree, quality, and accuracy of your data. Using provenance, you can ascertain the quality of data based on its ancestral data and derivations, track back to sources of errors, allow automatic re-enactment of derivations to update data, and provide attribution of the data source. Secure Data Provenance and Inference Control with Semantic Web supplies step-by-step instructions on how to secure the provenance of your data to make sure it is safe from inference attacks. It details the design and implementation of a policy engine for provenance of data and presents case studies that illustrate solutions in a typical distributed health care system for hospitals. Although the case studies describe solutions in the health care domain, you can easily apply the methods presented in the book to a range of other domains.The book describes the design and implementation of a policy engine for provenance and demonstrates the use of Semantic Web technologies and cloud computing technologies to enhance the scalability of solutions. It covers Semantic Web technologies for the representation and reasoning of the provenance of the data and provides a unifying framework for securing provenance that can help to address the various criteria of your information systems. Illustrating key concepts and practical techniques, the book considers cloud computing technologies that can enhance the scalability of solutions. After reading this book you will be better prepared to keep up with the on-going development of the prototypes, products, tools, and standards for secure data management, secure Semantic Web, secure web services, and secure cloud computing.…

Buch. Condizione: Neu. Neuware - Although molecular modeling has been around for a while, the groundbreaking advancement of massively parallel supercomputers and novel algorithms for parallelization is shaping this field into an exciting new area. Developments in molecular modeling from experimental and computational techniques have enabled a wide range of biological applications. Responding to this renaissance, Molecular Modeling at the Atomic Scale: Methods and Applications in Quantitative Biology includes discussions of advanced techniques of molecular modeling and the latest research advancements in biomolecular applications from leading experts.The book begins with a brief introduction of major methods and applications, then covers the development of cutting-edge methods/algorithms, new polarizable force fields, and massively parallel computing techniques, followed by descriptions of how these novel techniques can be applied in various research areas in molecular biology. It also examines the self-assembly of biomacromolecules, including protein folding, RNA folding, amyloid peptide aggregation, and membrane lipid bilayer formation. Additional topics highlight biomolecular interactions, including protein interactions with DNA/RNA, membrane, ligands, and nanoparticles. Discussion of emerging topics in biomolecular modeling such as DNA sequencing with solid-state nanopores and biological water under nanoconfinement round out the coverage.This timely summary contains the perspectives of leading experts on this transformation in molecular biology and includes state-of-the-art examples of how molecular modeling approaches are being applied to critical questions in modern quantitative biology. It pulls together the latest research and applications of molecular modeling and real-world expertise that can boost your research and development of applications in this rapidly changing field.…

Buch. Condizione: Neu. Neuware - A Step-by-Step Guide to Describing Biomolecular StructureComputational and Visualization Techniques for Structural Bioinformatics Using Chimera shows how to perform computations with Python scripts in the Chimera environment. It focuses on the three core areas needed to study structural bioinformatics: biochemistry, mathematics, and computation.Understand Important Concepts of Structural BioinformaticsThe book covers topics that deal primarily with protein structure and includes many exercises that are grounded in biological problems at the molecular level. The text encourages mathematical analysis by providing a firm foundation for computations. It analyzes numerous Python scripts for the Chimera environment, with the scripts and other material available on a supplementary website.Build Python Scripts to Extend the Capabilities of ChimeraThrough more than 60 exercises that involve the development of Python scripts, the book gives you concrete guidance on using the scripting capabilities of Chimera. You'll gain experience in solving real problems as well as understand the various applications of linear algebra. You can also use the scripts as starting points for the development of similar applications and use classes from the StructBio toolkit for computations, such as structure overlap, data plotting, scenographics, and display of residue networks.Print Versions of this book also include access to the Elektronisches Buch version.…

Buch. Condizione: Neu. Neuware - Nonalcoholic fatty liver disease is one of the most common liver diseases worldwide affecting patients from all ages, races, and ethnic backgrounds. It comprises a spectrum of hepatic pathology ranging from simple steatosis, in which there is an increase of fat accumulation in hepatocytes, to nonalcoholic steatohepatitis and cirrhosis. The significant prevalence of this disease-between 15 and 45 percent of the general population-means that it contributes to an increased burden of ill health both today and in the future.Liver Metabolism and Fatty Liver Disease addresses the current understanding of the development of nonalcoholic fatty liver disease as well as the clinical aspects of the disease by examining the current knowledge surrounding metabolism in the liver. The book discusses various topics including the involvement of oxidative stress, metabolic effects, and inflammation as well as the effect of nutrition on the development and progression of the disease.…

Buch. Condizione: Neu. Neuware - This new edition of a bestseller has gone through a thorough update and continues to provide a comprehensive introduction to materials and their properties. It begins by discussing ferrous and non-ferrous materials and their heat treatment and then moves on to discuss non-conventional materials. The book covers the processes of casting and jointing as well as welding. Additional topics include forming operation, cutting tool materials, solid stoke welding, the theory of metal cutting, machining operations, and design considerations in joining processes. It concludes with a new chapter on Manufacturing Tools and Workshop Applications.…

Buch. Condizione: Neu. Neuware - China is the world's top agricultural producer according to a World Trade Organization 2010 report, but a growing number of alarming safety issues has put the world's top manufacturer of food on the defensive. Food Safety in China: A Comprehensive Review chronicles China's current food safety problems from a professional perspective. This text describes key concepts, incorporates a research thread, considers various methods, provides context, and presents main conclusions. Containing investigative research and presenting an authoritative analysis of the subject, this text considers the complex issues that span the entire food supply chain system. It provides an overview of the current food safety situation, as well as its development and changes. It also details the structure of the food safety support system, and addresses growing concerns.Explores Involvement in Stages The book considers the interrelationship between the government, producers and traders, and consumers. It studies technical and management issues, and explains how that impacts businesses, the government regulatory system, and the end user. Factoring in the risks that can be caused by both natural and human influences, including the abuse of food additives, this book reviews the efforts put forth by China to prevent food safety issues. It examines the changing track of food safety (including imported and exported products) in key aspects such as production, circulation, and consumption from 2006 to 2011 based on empirical investigation and comprehensive use of various statistical data, and examines most specifically China's food safety situation in 2011.This book addresses: - Food production and processing - Food transportation - Food consumption - Environment and consumer awareness of food safety - Efforts and techni.…

Buch. Condizione: Neu. Neuware - Nutrition and infection are often at a crossroads, interacting with each other and influencing human health. Infection is a major health problem and nutritional deficiency plays a significant role in increasing the risk of infection. Nutrition-Infection Interactions and Impacts on Human Health presents state-of-the-art evidence on nutrition-infection interactions and their impact on health and disease. The book explores a wide range of topics including the effects of infection on nutrition-a common occurrence in the developing world-and nutrient-infection interactions for specific infections including HIV, TB, malaria, and parasitic infections. These are reviewed with a special emphasis on nutritional interventions. Also covered is the role of the gastrointestinal tract and its influence on nutrition, focusing on the human gastrointestinal microbiota, enteric syndromes, probiotics, and immunonutrients. The book discusses infection-nutrition interactions in special age groups such as children, adolescents, and the elderly. It also reviews emerging nutritional and anti-infective strategies with an emphasis on future research directions. The book is useful for epidemiologists, nutritionists, and health care staff caring for patients. The book's broad scope allows for its applicability to both the developed and the developing world.…

Buch. Condizione: Neu. Neuware - Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs that showed neuroprotection in the experimental setting failed to translate into the clinic because of their toxicity or lack of efficacy.Researchers in the field now face the crucial need to develop effective stroke therapies and successfully translate novel strategies into the clinical setting. Rational Basis for Clinical Translation in Stroke Therapy presents the most recent promising preclinical approaches and the most updated clinical evidence for treating stroke patients. By bringing together the experience of accomplished stroke researchers and clinicians, the book is a useful tool for improving the treatment and management of stroke patients.The book describes current approaches for the management of stroke patients including thrombolysis and mechanical recanalization procedures as well as other clinically relevant topics such as diagnosis, imaging, risk factors, and prevention. Also described are emerging interventions based on the use of stem cells, botulinum toxin, and antidepressants which complement emergency stroke treatment and conventional rehabilitation procedures. Clinical approaches are integrated with the most promising therapeutic opportunities based on targeting the immune system, hypothermia, and postconditioning. The book also covers issues related to the improvement of R&D strategies in stroke therapeutics, aimed at the implementation of preclinical approaches with stroke model guidelines and at the optimization of clinical trial design. This volume is a reference for all those interested in the rational development of novel stroke therapeutics.…

Buch. Condizione: Neu. Neuware - Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensive-both on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates.…

Buch. Condizione: Neu. Neuware - Metallic Spintronic Devices provides a balanced view of the present state of the art of metallic spintronic devices, addressing both mainstream and emerging applications from magnetic tunneling junction sensors and spin torque oscillators to spin torque memory and logic. Featuring contributions from well-known and respected industrial and academic experts, this cutting-edge work not only presents the latest research and developments but also: - Describes spintronic applications in current and future magnetic recording devices - Discusses spin-transfer torque magnetoresistive random-access memory (STT-MRAM) device architectures and modeling - Explores prospects of STT-MRAM scaling, such as detailed multilevel cell structure analysis - Investigates spintronic device write and read optimization in light of spintronic memristive effects - Considers spintronic research directions based on yttrium iron garnet thin films, including spin pumping, magnetic proximity, spin hall, and spin Seebeck effects - Proposes unique solutions for low-power spintronic device applications where memory is closely integrated with logic Metallic Spintronic Devices aims to equip anyone who is serious about metallic spintronic devices with up-to-date design, modeling, and processing knowledge. It can be used either by an expert in the field or a graduate student in course curriculum.…

Buch. Condizione: Neu. Neuware - A Complex and Growing FieldThe study of vascularization in tissue engineering and regenerative medicine (TERM) and its applications is an emerging field that could revolutionize medical approaches for organ and tissue replacement, reconstruction, and regeneration. Designed specifically for researchers in TERM fields, Vascularization: Regenerative Medicine and Tissue Engineering provides a broad overview of vascularization in TERM applications. This text summarizes research in several areas, and includes contributions from leading experts in the field. It defines the difficulties associated with multicellular processes in vascularization and cell-source issues. It presents advanced biomaterial design strategies for control of vascular network formation and in silico models designed to provide insight not possible in experimental systems. It also examines imaging methods that are critical to understanding vascularization in engineered tissues, and addresses vascularization issues within the context of specific tissue applications. This text is divided into three parts; the first section focuses on the basics of vascularization. The second section provides general approaches for promoting vascularization. The final section presents tissue and organ-specific aspects of vascularization in regenerative medicine. Presents Areas of Substantial Clinical and Societal ImpactThe material contains research and science on the process of vessel assembly with an emphasis on methods for controlling the process for therapeutic applications. It describes the tissue and organ-specific aspects of vascularization in regenerative medicine, and refers to areas such as bone tissue engineering, vascularization of encapsulated cells, adipose tissue, bone and muscle engineering. It also provides a mechanistic understanding of the process and presentation of experimental and computational approaches that facilitate the study of vascular assembly, and includes enabling technologies such as nanotechnology, drug delivery, stem cells, microfluidics, and biomaterial design that are optimized for supporting the formation of extensive vascular networks in regenerative medicine.A guide for researchers developing new methods for modulating vessel assembly, this text can also be used by senior undergraduate and graduate students taking courses focused on TERM. …

Kombiprodukt. Condizione: Neu. Neuware - The behaviour of river systems is a result of the complex interaction between flow, sediments, morphology and habitats. Furthermore, rivers are often used as a source of water supply and energy production as well as a waterway for transportation. The main challenge faced by river engineers today, in collaboration with environmental and ecological scientists, is to restore the channelized rivers under the constraints of high urbanization and limited space, as well as sustainable water use.During the seventh International Conference on Fluvial Hydraulics River Flow 2014 at cole Polytechnique F d rale de Lausanne (EPFL), Switzerland, scientists and professionals from all over the world addressed this challenge and exchanged their knowledge regarding fluvial hydraulics and river morphology. This book comprises the proceedings of the high quality contributions of the participants, which reflect the state-of-the-art in the fields of river hydrodynamics, morphodynamics, sediment transport, river engineering and restoration. The conference was organized under the auspices of the Committee on Fluvial Hydraulics of the International Association for Hydro-Environment Engineering and Research (IAHR). Past River Flow conferences have witnessed a significant increase in participation of our community of river engineers and researchers, confirming the need for such a forum.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Get Up to Speed on PhysicsUpdated and expanded with new topics, The Physics Companion, 2nd Edition offers a unique and educational approach to learning physics at a level suitable for first-year science students. This new edition expands the presentation to include senior topics, such as statistical mechanics, quantum physics, and nuclear physics. A Convenient, Student-Friendly Format Rich with Diagrams and Clear ExplanationsThis useful book serves students from the beginning of their studies to well into their future careers. It provides detailed graphics, simple and clear explanations of difficult concepts, and annotated mathematical treatments in a one-page-per-topic format that is the signature style of the author's companion books.Be sure to check out the author's other companion books:The Mathematics Companion: Mathematical Methods for Physicists and Engineers, 2nd EditionThe Materials Physics Companion, 2nd EditionThe Electronics Companion: Devices and Circuits for Physicists and Engineers, 2nd EditionThe Chemistry Companion 570 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Solve Complex Ground and Foundation ProblemsPresenting more than 25 years of teaching and working experience in a wide variety of centrifuge testing, the author of Centrifuge Modelling for Civil Engineers fills a need for information about this field. This text covers all aspects of centrifuge modelling. Expertly explaining the basic principles, the book makes this technique accessible to practicing engineers and researchers.Appeals to Non-Specialists and Specialists AlikeCivil engineers that are new to the industry can refer to this material to solve complex geotechnical problems. The book outlines a generalized design process employed for civil engineering projects. It begins with the basics, and then moves on to increasingly complex methods and applications including shallow foundations, retaining walls, pile foundations, tunnelling beneath existing pile foundations, and assessing the stability of buildings and their foundations following earthquake-induced soil liquefaction. It addresses the use of modern imaging technique, data acquisition, and modelling techniques. It explains the necessary signal processing tools that are used to decipher centrifuge test data, and introduces the reader to the specialist aspects of dynamic centrifuge modelling used to study dynamic problems such as blast, wind, or wave loading with emphasis on earthquake engineering including soil liquefaction problems. Introduces the equipment and instrumentation used in centrifuge testing Presents in detail signal processing techniques such as smoothing and filtering Provides example centrifuge data that can be used for sample analysis and interpretation Centrifuge Modelling for Civil Engineers effectively describes the equipment, instrumentation, and signal processing techniques required to make the best use of the centrifuge modelling and test data. This text benefits graduate students, researchers, and practicing civil engineers involved with geotechnical issues. 324 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Give Your Students the Proper Groundwork for Future Studies in OptimizationA First Course in Optimization is designed for a one-semester course in optimization taken by advanced undergraduate and beginning graduate students in the mathematical sciences and engineering. It teaches students the basics of continuous optimization and helps them better understand the mathematics from previous courses.The book focuses on general problems and the underlying theory. It introduces all the necessary mathematical tools and results. The text covers the fundamental problems of constrained and unconstrained optimization as well as linear and convex programming. It also presents basic iterative solution algorithms (such as gradient methods and the Newton-Raphson algorithm and its variants) and more general iterative optimization methods. This text builds the foundation to understand continuous optimization. It prepares students to study advanced topics found in the author's companion book, Iterative Optimization in Inverse Problems, including sequential unconstrained iterative optimization methods. 316 pp. Englisch.…