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Paperback. Condizione: new. Paperback. Immunohistochemistry no longer only names a tumour - increasingly, it chooses the drug. A membrane score gates an antibody-drug conjugate; a percentage of stained nuclei opens or closes a line of therapy; a pattern of nuclear loss unlocks immunotherapy across the body.Yet the threshold that decides treatment is not a fact about the tumour. It is a decision rule tied to a particular trial, a particular drug, and a particular assay. For every predictive marker, this pan-tumour guide sets out what to score, where the cutoff came from, how reproducibly it can be read, and how to report it in language the oncologist can act on.Markers covered: PD-L1 - HER2 and HER2-low/ultralow - MMR/MSI - ER, PR and Ki-67 - Trop-2 - Nectin-4 - FRa - Claudin 18.2 - HER3 - B7-H3 - quantitative and AI-assisted scoring.Inside this edition: fifteen focused chapters across four parts; the trial-validated cutoff behind every marker; reproducibility and the faint-end problem, marker by marker; pitfalls at the bench, controls, and external quality assurance; assay, clone and platform specifics throughout; and synoptic reporting templates.Written for practising pathologists, trainees, and tumour-board participants.Expression is not eligibility. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Paperback. Condizione: new. Paperback. The modern haematopathology trainee works between two registers: authoritative textbooks that revise slowly, and a WHO classification that updates faster than any of them.Integrated Pathology, Volume 1 covers haematopathology and transfusion medicine across 48 chapters, from haematopoiesis to transfusion practice. Written for FRCPath candidates, international residents, and early-career consultants, it includes three practical-examination chapters - peripheral smear, bone marrow, and coagulation and blood bank - built for the OSPE-style and table-side formats most haematopathology texts leave out.Every chapter runs on the same five elements: a Big Picture frame that fixes the concept before the detail; Quick Recall boxes for revision; Exam Pitfall flags for the traps examiners set; Pathologist's Eye sign-out reasoning; and International Frameworks panels reconciling the WHO 5th Edition and ICC 2022 classifications across malignant haematology, the anaemias, haemostasis, and blood banking.More than 140 figures pair open-licence photomicrographs with stepwise diagnostic algorithms for the acute and chronic leukaemias, lymphomas, plasma cell neoplasms, myelodysplastic and myeloproliferative neoplasms, and haemostatic disorders. Every topic is mapped to the current FRCPath syllabus and to the way these diagnoses are reached at the bench. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Paperback. Condizione: new. Paperback. Immunohistochemistry no longer only names a tumour - increasingly, it chooses the drug. A membrane score gates an antibody-drug conjugate; a percentage of stained nuclei opens or closes a line of therapy; a pattern of nuclear loss unlocks immunotherapy across the body.Yet the threshold that decides treatment is not a fact about the tumour. It is a decision rule tied to a particular trial, a particular drug, and a particular assay. For every predictive marker, this pan-tumour guide sets out what to score, where the cutoff came from, how reproducibly it can be read, and how to report it in language the oncologist can act on.Markers covered: PD-L1 - HER2 and HER2-low/ultralow - MMR/MSI - ER, PR and Ki-67 - Trop-2 - Nectin-4 - FRa - Claudin 18.2 - HER3 - B7-H3 - quantitative and AI-assisted scoring.Inside this edition: fifteen focused chapters across four parts; the trial-validated cutoff behind every marker; reproducibility and the faint-end problem, marker by marker; pitfalls at the bench, controls, and external quality assurance; assay, clone and platform specifics throughout; and synoptic reporting templates.Written for practising pathologists, trainees, and tumour-board participants.Expression is not eligibility. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

Paperback. Condizione: new. Paperback. The modern haematopathology trainee works between two registers: authoritative textbooks that revise slowly, and a WHO classification that updates faster than any of them.Integrated Pathology, Volume 1 covers haematopathology and transfusion medicine across 48 chapters, from haematopoiesis to transfusion practice. Written for FRCPath candidates, international residents, and early-career consultants, it includes three practical-examination chapters - peripheral smear, bone marrow, and coagulation and blood bank - built for the OSPE-style and table-side formats most haematopathology texts leave out.Every chapter runs on the same five elements: a Big Picture frame that fixes the concept before the detail; Quick Recall boxes for revision; Exam Pitfall flags for the traps examiners set; Pathologist's Eye sign-out reasoning; and International Frameworks panels reconciling the WHO 5th Edition and ICC 2022 classifications across malignant haematology, the anaemias, haemostasis, and blood banking.More than 140 figures pair open-licence photomicrographs with stepwise diagnostic algorithms for the acute and chronic leukaemias, lymphomas, plasma cell neoplasms, myelodysplastic and myeloproliferative neoplasms, and haemostatic disorders. Every topic is mapped to the current FRCPath syllabus and to the way these diagnoses are reached at the bench. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…