Elsevier bv mär 1997 (7 risultati)

Buch. Condizione: Neu. Neuware - This is the 19th volume in a series of reviews of research in organizational behaviour. This volume covers such topics as: motivational traits and skills; the dispositional causes of job satisfaction; the ways and means of studying group processes; and managing grand scale construction projects.…

Buch. Condizione: Neu. Neuware - Historically the field of endocrine research has always been at the forefront of scientific endeavors. The investigators of these important breakthroughs in research have been rewarded by numerous Nobel awards. In the field of diabetes alone, Nobel prizes have been awarded to researchers who discovered insulin, characterized the protein and invented radioimmunoassays using insulin as a paradigm. Not surprisingly, biomedical researchers have always been attracted by the endocrine system and other similar systems of intercellular communication.Over the past two decades, endocrine research has developed rapidly and adapted modern molecular and cellular biology techniques for its specific use. These changes have allowed researchers in the field to maintain their edge. Thus, endocrine disease-related genes have been characterized and mutations in these genes have helped explain common and less common endocrine disorders. Our understanding of the regulation of gene expression has been greatly enhanced by molecular techniques.In an attempt to bring investigators up to date with the recent advances in this exploding field we have decided to publish a series entitled Advances in Molecular and Cellular Endocrinology. Internationally famous investigators have agreed to participate and their contributions are appreciated.Volume 1 has focused on aspects of the hypothalamic-pituitary axis including GnRH and GH gene regulation, molecular aspects of insulin, insulin-like growth factors and glucagon. In addition, reviews on the recently cloned calcium receptor and steroid receptor interactions with DNA are presented.…

Buch. Condizione: Neu. Neuware - Volume 6 of Biomembranes covers transmembrane receptors and channels. A particularly important role for the membrane is that of passing messages between a cell and its environment. Part I of this volume covers receptors for hormones and growth factors. Here, as in so many other areas of cell biology, the application of the methods of molecular biology have led to the recognition of a number of families of receptors. Typically, such receptors contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular catalytic domain whose activation, as a result of ligand binding, leads to generation of second messengers within the cell and stimulation of a range of cytosolic enzymes. An alternative signaling strategy, exploited in particular in the nervous system, is to use ion channels to allow controlled movement of monovalent (Na+, K+) or divalent (Ca2+) cations in or out of the cell, resulting in changes in membrane potential or alterations in the intracellular concentration of Ca2+. Part II of this volume is concerned with these ion channels and with other, often simpler, ion channel systems whose study can throw light on channel mechanism.…

Buch. Condizione: Neu. Neuware - The present volume is the first in the advances in oncobiology series. It is meant to be useful not only to clinical and non-clinical oncologists but also to graduate students and medical students. The individual chapters are presented as self-contained summaries of current knowledge rather than as reviews. The last chapter deals with the subject of chemotherapy.…

Buch. Condizione: Neu. Neuware - In recent years the most significant advances in carbohydrate research have been made in the knowledge of the structure and function of carbohydrates in the macromolecular state. This title addresses those areas of the subject in which the authors believe the most important work is being carried out.…

Buch. Condizione: Neu. Neuware - The aim of this book is to present the fundamental theoretical results concerning inference rules in deductive formal systems. Primary attention is focused on:¿ admissible or permissible inference rules¿ the derivability of the admissible inference rules¿ the structural completeness of logics¿ the bases for admissible and valid inference rules.There is particular emphasis on propositional non-standard logics (primary, superintuitionistic and modal logics) but general logical consequence relations and classical first-order theories are also considered.The book is basically self-contained and special attention has been made to present the material in a convenient manner for the reader. Proofs of results, many of which are not readily available elsewhere, are also included.The book is written at a level appropriate for first-year graduate students in mathematics or computer science. Although some knowledge of elementary logic and universal algebra are necessary, the first chapter includes all the results from universal algebra and logic that the reader needs. For graduate students in mathematics and computer science the book is an excellent textbook.…

Buch. Condizione: Neu. Neuware - In the study of the computational structure of biological/robotic sensorimotor systems, distributed models have gained center stage in recent years, with a range of issues including self-organization, non-linear dynamics, field computing etc. This multidisciplinary research area is addressed here by a multidisciplinary team of contributors, who provide a balanced set of articulated presentations which include reviews, computational models, simulation studies, psychophysical, and neurophysiological experiments.The book is divided into three parts, each characterized by a slightly different focus: in part I, the major theme concerns computational maps which typically model cortical areas, according to a view of the sensorimotor cortex as 'geometric engine' and the site of 'internal models' of external spaces. Part II also addresses problems of self-organization and field computing, but in a simpler computational architecture which, although lacking a specialized cortical machinery, can still behave in a very adaptive and surprising way by exploiting the interaction with the real world. Finally part III is focused on the motor control issues related to the physical properties of muscular actuators and the dynamic interactions with the world.The reader will find different approaches on controversial issues, such as the role and nature of force fields, the need for internal representations, the nature of invariant commands, the vexing question about coordinate transformations, the distinction between hierachiacal and bi-directional modelling, and the influence of muscle stiffness.…