Elsevier inc apr 2019 (50 risultati)

Taschenbuch. Condizione: Neu. Neuware - Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.…

Taschenbuch. Condizione: Neu. Neuware - Deep Learning through Sparse Representation and Low-Rank Modeling bridges classical sparse and low rank models-those that emphasize problem-specific Interpretability-with recent deep network models that have enabled a larger learning capacity and better utilization of Big Data. It shows how the toolkit of deep learning is closely tied with the sparse/low rank methods and algorithms, providing a rich variety of theoretical and analytic tools to guide the design and interpretation of deep learning models. The development of the theory and models is supported by a wide variety of applications in computer vision, machine learning, signal processing, and data mining. This book will be highly useful for researchers, graduate students and practitioners working in the fields of computer vision, machine learning, signal processing, optimization and statistics.…

Taschenbuch. Condizione: Neu. Neuware - The Accelerating Transport Innovation Revolution: A Global, Case Study-based Assessment of Current Experience, Cross-sectorial Effects and Socioeconomic Transformations, offers a comprehensive view of current state-of-the-art and practices around the world to create innovation on a revolutionary scale and connect research to commercial exploitation of its results. It offers a fascinating new model of the innovation process based on theories of biological ecosystems, general systems theory and basins of attraction (represented through space-time graphs well known in mathematics). Furthermore, it considers - through a number of dedicated chapters - key issues and elements of innovation ecosystems, such as: Causal Factors and system constraints affecting the development and sustainability of innovation ecosystems (Chapter 4); Review of innovation organization and governance in key countries and regions (Chapter 5); the role of technological 'Spillovers' (Chapter 6); Collection and use of data for innovation monitoring and benchmarking (Chapter 7); Intellectual Property protection between competing ecosystems (Chapter 8); Economics of innovation (Chapter 9); Public and private sector involvement in Transport innovation creation (Chapter 10); the role of the individual entrepreneur - innovator in energizing change (Chapter 11). Finally, in Chapter 12, there is a thorough summary of key findings. This book uses a paradigmatic approach to augment the innovation ecosystem model of innovation that integrates beliefs and learning into the innovation ecosystems model. It therefore includes ten case studies from the U.S., Europe and Asia, detailing how innovation is created across continents and different ecosystems and what are the critical lessons to be learned. It does this, effectively, at five different levels of analysis i.e. the individual innovator / entrepreneur level, the organization level (government agency or company), the regional ecosystem level, the nation-state level and the global - systemic or international level. Each level of analysis, reveals unique features of the innovation landscape and the ten case studies allow the reader to assess when and where specific 'enablers' are facilitating innovation especially on a revolutionary scale. The need for the book came from the realization that despite the billions of dollars spent on various research programs over the past 20 years (especially in the public sector), there have been few clear and tangible efforts directed at exploring how innovation production increasingly occurs and the critical factors necessary to sustain large-scale, revolutionary change as the future unfolds. Thus, a primary theme of the book is that understanding how research results translate into market innovation and implementation, especially understanding the nature of revolutionary innovation, is as important as the creation of innovations themselves. While the focus of the book is on Transportation, the concepts and recommendations presented apply to other fields too.…

Taschenbuch. Condizione: Neu. Neuware - Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.…

Taschenbuch. Condizione: Neu. Neuware - Pediatric Anxiety Disorders provides a critical, updated and comprehensive overview of anxiety disorders in children and adolescents based on the current state of empirical research. The book provides specific clinical recommendations which integrate new knowledge from neuroscience and innovative delivery formats for interventions. This is the first reference to examine anxiety diagnoses in accordance with the latest edition of the DSM-5, including childhood onset disorders, such as Separation Anxiety Disorder, Selective Mutism, Specific Phobia, Social Anxiety Disorder, Panic Disorder, Agoraphobia and Generalized Anxiety Disorder. The book assists clinicians in critically appraising the certainty of the evidence-base and the strength of clinical recommendations.…

Taschenbuch. Condizione: Neu. Neuware - Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data.…

Taschenbuch. Condizione: Neu. Neuware - Adjustment Models in 3D Geomatics and Computational Geophysics: With MATLAB Examples, Volume Four introduces a complete package of theoretical and practical subjects in adjustment computations relating to Geomatics and geophysical applications, particularly photogrammetry, surveying, remote sensing, GIS, cartography, and geodesy. Supported by illustrating figures and solved examples with MATLAB codes, the book provides clear methods for processing 3D data for accurate and reliable results. Problems cover free net adjustment, adjustment with constraints, blunder detection, RANSAC, robust estimation, error propagation, 3D co-registration, image pose determination, and more.…

Taschenbuch. Condizione: Neu. Neuware - The US Gulf of Mexico is one of the largest and most prolific offshore hydrocarbon basins in the world with thousands of structures installed in the region and tens of thousands of wells drilled. Over the past decade, a significant number of structures in shallow water have been decommissioned, as operators can no longer 'kick the decommissioning can' down the road. This has opened up new markets and additional regulatory oversight with far-reaching implications. This book describes future decommissioning trends and issues and provides guidance for operator budgeting, regulatory oversight, and service sector companies interested in participating in the field. Decommissioning Forecasting and Operating Cost Estimation is the first of its kind textbook to develop models to forecast platform decommissioning in the Gulf of Mexico and to better understand the dynamics of offshore production cost. The book bridges the gap between modeling and technical knowledge to provide insight into the sector. Topics are presented in five parts covering fundamentals, structure inventories and well trends, decommissioning modeling, critical infrastructure issues, and operating cost estimation. Factor models and activity-based cost models in operating cost estimation conclude the discussion. Decommissioning Forecasting and Operating Cost Estimation helps oil and gas professionals navigate through this complex and challenging field providing an invaluable resource for academics, researchers, and professionals. The book will also serve government regulators, energy and environmental engineers, offshore managers, financial analyst, and others interested in this fascinating and dynamic industry.…

Taschenbuch. Condizione: Neu. Neuware - The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient's quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.…

Taschenbuch. Condizione: Neu. Neuware - Dynamics of Rail Transit Tunnel Systems develops the dynamic theory of a rail transit tunnel system and provides research methods for the evaluation of long-term settlement of rail transit tunnels in soft soil, the service performance of tunnel structures, and the characterization of environmental vibration induced by trains. In recent years, a large number of rail transit tunnels have been constructed and put into operation, particularly in China. To evaluate the time-dependent degradation of tunnel structures and train-induced environmental vibration, a reliable model must be established to determine the dynamic response of a vehicle-track-tunnel-soil system, hence the introduction of this timely resource.…

Buch. Condizione: Neu. Neuware - Echinoderms, Volume 151, the latest release in the Methods in Cell Biology series, highlights advances in the field, with this update presenting chapters on Echinoderm Genome Databases, analysis of gene regulatory networks, using ATAC-seq and RNA-seq to increase resolution in GRN connectivity, multiplex cis-regulatory analysis, experimental approaches GRN/signal pathways, BACs, analysis of chromatin accessibility using ATAC-seq, analysis of sea urchin proteins /Click IT, CRISPR/Cas9-mediated genome editing in sea urchins, super-resolution and in toto imaging of echinoderm embryos, and methods for analysis of intracellular ion signals in sperm, eggs and embryos.…

Taschenbuch. Condizione: Neu. Neuware - In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.…

Taschenbuch. Condizione: Neu. Neuware - Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications.…

Buch. Condizione: Neu. Neuware - Self-assembly of Nano- and Micro-structured Materials Using Colloidal Engineering, Volume 12, covers the recent breakthroughs in the design and manufacture of functional colloids at the micro- and nanoscale level. In addition, it provides analyses on how these functionalities can be exploited to develop self-assembly pathways towards nano- and micro-structured materials. As we seek increasingly complex functions for colloidal superstructures, in silico design will play a critical role in guiding experimental fabrication by reducing the element of trial-and-error that would otherwise be involved. In addition to novel experimental approaches, recent developments in computational modelling are also presented, along with an overview of the arsenal of designing tools that are available to the modern materials scientist.…

Taschenbuch. Condizione: Neu. Neuware - Dislocation Based Crystal Plasticity: Theory and Computation at Micron and Submicron Scale provides a comprehensive introduction to the continuum and discreteness dislocation mechanism-based theories and computational methods of crystal plasticity at the micron and submicron scale. Sections cover the fundamental concept of conventional crystal plasticity theory at the macro-scale without size effect, strain gradient crystal plasticity theory based on Taylar law dislocation, mechanism at the mesoscale, phase-field theory of crystal plasticity, computation at the submicron scale, including single crystal plasticity theory, and the discrete-continuous model of crystal plasticity with three-dimensional discrete dislocation dynamics coupling finite element method (DDD-FEM). Three kinds of plastic deformation mechanisms for submicron pillars are systematically presented. Further sections discuss dislocation nucleation and starvation at high strain rate and temperature effect for dislocation annihilation mechanism.…

Taschenbuch. Condizione: Neu. Neuware - Advanced Nanomaterials for Solar Cells and Light Emitting Diodes discusses the importance of nanomaterials as the active layers in solar cells and light emitting diodes (LEDs), along with the progress of nanomaterials as the electron and hole transporting layers. Specifically, the book reviews the use of nano-morphology of polymers, small molecules, and the organic-inorganic perovskites as the active layers in solar cells and LEDs. The design, fabrication and properties of metal-oxide-based nano-structures as electron and hole transporting layers are also reviewed. In addition, the development of plasmonic nanomaterials for solar cells and LEDs is discussed. Each topic in this book includes an overview of the materials system from principles to process. The advantages, disadvantages and related methodologies are highlighted. The book includes applications based on materials and emphasize how to improve the performance of solar cells and LEDs by the materials design, with a focus on nanomaterials.…

Taschenbuch. Condizione: Neu. Neuware - Japan's Quest for Nuclear Energy and the Price it has Paid: Accidents, Consequences, and Lessons Learned for the Global Nuclear Industry identifies major accidents in Japan that have happened at different stages of the nuclear fuel cycle in Japan, assesses the underlying causes of nuclear accidents, and identifies other systemic problems in the nuclear industry. It provides recommendations on how government, industry and academic institutions can work together toward achieving a zero-accident safety culture.…

Taschenbuch. Condizione: Neu. Neuware - Alcoholic Beverages, Volume Seven in The Science of Beverages series, is a multidisciplinary resource for anyone who needs deeper knowledge on the most recent approaches in beverage development, technology, and engineering, along with their effects on beverage composition, quality, sensory and nutritional features. The book discusses main alcoholic beverages, such as spirits and wines that are thoroughly analyzed in terms of production, sustainability, and future perspectives. It offers examples of the new trends and the most recent technologies and approaches in the industry of alcoholic drinks.…

Taschenbuch. Condizione: Neu. Neuware - Materials for Biomedical Engineering: Nanobiomaterials in Tissue Engineering highlights the impact of novel bioactive materials in both current applications and their potential in the future progress of tissue engineering and regenerative medicine. Tissue engineering is a well investigated and challenging bio-medical field, with promising perspectives to improve and support the quality of life in diseased patients. This book brings together the latest research findings regarding the design and versatility of bioactive materials and their potential in tissue engineering. In addition, recent progress in soft and hard tissue engineering is presented within the chapters of the book.…

Taschenbuch. Condizione: Neu. Neuware - Caffeinated and Cocoa Based Beverages, Volume Eight in The Science of Beverages series, covers one of the hottest topics in the current beverage industry. This practical reference takes a broad and multidisciplinary approach on the production, processing, and engineering approaches to caffeinated drinks, highlighting their biological impact and health-related interference. The book presents evidence-based examples of the benefits of caffeinated and cocoa-based beverages and analyzes the latest trends in the industry that are essential for researchers in various fields of food and beverage development, including coverage of pharmaceuticals and the biomedical fields.…

Taschenbuch. Condizione: Neu. Neuware - Second and Third Generation of Feedstocks: The Evolution of Biofuels presents a critical analysis of both the applications and potential of bioenergy production from second and third generation feedstocks. The book illustrates different aspects of the processes used for the production of biofuels, dealing specifically with second and third generation feedstocks from biomass and algae. The pretreatment of feedstocks and optimization of various forms of bioenergy are considered, along with the economic aspects of the various processes. In the last few years, industrial research efforts have focused on low cost, large-scale processing for lignocellulosic feedstocks originating from agricultural residues and municipal wastes for bioenergy production. This book shares an insight into the recent developments taking place in this industry, exploring transformation processes as well as biomass and algae conversions.…

Taschenbuch. Condizione: Neu. Neuware - Materials for Biomedical Engineering: Hydrogels and Polymer-Based Scaffolds discusses the use of a wide variety of hydrogels as bioactive scaffolds in regenerative medicine, including updates on innovative materials and their properties. Various types of currently investigated scaffolding materials and hydrogels are discussed, as is their future roles and applications, the main techniques for scaffold fabrication, and their characterization procedures. Readers will be able to use this book as a guide for the selection of the best materials for a specific application.…

Taschenbuch. Condizione: Neu. Neuware - Materials for Biomedical Engineering: Inorganic Micro- and Nanostructures presents recent, specific insights in new progress, along with new perspectives for inorganic micro- and nano-particles. The main focus of this book is on biomedical applications of these materials and how their biological properties are linked to various synthesis methods and their source of raw materials. Recent information regarding optimized synthesis methods to obtain improved nano- and microparticles for biomedical use, as well as the most important biomedical applications of these materials, such as the diagnosis and therapy of cancer, are highlighted in detail.…

Buch. Condizione: Neu. Neuware - The Effect of UV Light and Weather on Plastics and Elastomers, Fourth Edition, provides critical data on the effect of UV light and weathering on plastics and elastomers, enabling engineers, designers and R&D professionals to select the right materials when developing plastics products for a range of industries and applications. This information will also support academic researchers and scientists in developing polymeric materials for advanced applications.…

Buch. Condizione: Neu. Neuware - Fluoropolymer Additives, Second Edition provides practical information on this group of additives, along with their applications and proper and safe handling. Chapters cover how commercial additives have been updated, providing a starting point where readers can begin the process of selection of additives for their own applications. Fully updated sections on applications provide the readers with a step-by-step description of the techniques necessary to select and incorporate these additives in various products. This book is the only practical guide available on the selection and use of fluoropolymer additives. It will help readers optimize existing fluoropolymer applications and implement new initiatives. In recent years, the application of fluoropolymer additives has expanded significantly, with even the meaning of 'fluoropolymer additives' expanding from the relatively narrow definition of PTFE powder fillers to a wide variety of fluoropolymer elastomers used as processing aids for plastics processing techniques in extrusion, injection molding, and film blowing. In addition, fluropolymer additives are being increasingly used in inks, lubricants, and coatings.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware - Age Estimation: A Multidisciplinary Approach is the only reference in the field covering all techniques and methods involving age estimation from different perspectives in just one volume. The book provides comprehensive coverage of all aspects of age estimation: aging the living and the dead, human rights, and skeletal, dental, histological and biochemical techniques and methods available. Each chapter is written by internationally known expert contributors. Age Estimation: A Multidisciplinary Approach is a one of a kind resource for those involved in estimating the age of the living and the dead. 246 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Remote Fieldwork Supervision for BCBA® Trainees prepares BCBAs for supervising certification candidates, providing structure, scope, and sequence for supervision, as well as tactical recommendations for providing independent fieldwork supervision in a distance context. The book helps to resolve common challenges in supervision arrangements, such as maintaining professional behavior and encouraging practitioner self-care. The book follows the Behavior Analyst Certification Board's Fifth Edition Task List, and then goes beyond the required 8-hour supervision training to teach important clinical skills, such as ACT, RFT, executive function skills, OBM, and curriculum-based measures. 182 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Libraries have historically played a role as a community builder, providing resources and spaces where knowledge can be archived, shared and created. They can also play a pivotal role in fostering the public's understanding of science and scientific processes. From makerspaces to data visualization labs to exhibits, many libraries already delve into scientific explorations and many more could join them. Scientists often need to include 'broader impacts' goals in grant proposals, but they might not know where to begin or feel that they do not have the time to devote to public engagement. This is where libraries and librarians can help. Research in science communication also supports tapping into libraries for public engagement with science. Studies show that it is important for scientists to present findings in an apolitical way-not aligning with one solution or one way of thinking and not being seen as an activist (Druckman, 2015; Jamieson & Hardy, 2014). One of the core tenets of librarians and libraries is to present information in a neutral way. Research also shows that Informal conversations about science can have a greater effect on people than reading about it online or hearing about it on the news (Eveland & Cooper, 2013). Again, libraries can play a role in fostering these types of conversations. Given this landscape, this book will demonstrate concrete ways that libraries and librarians can play a role in fostering public engagement with science. In addition to background information on the current landscape of public knowledge and understanding of science, it will also include best practices and case studies of different types of programming and services that libraries can offer. Often libraries do not jump to mind when people think about science education or science literacy, and many librarians do not come from a science background. Literature on science programming and sharing science is largely absent from the library field. This book will help give confidence to librarians that they can participate in engaging the public with science. At the same time, it will provide a conduit to bring informal science educators, communication officers from universities or research organizations who share scientific discoveries with the public, and librarians together to explore ways to align their work to promote scientific literacy for all. 214 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Predicting Cyberbullying: Research, Theory, and Intervention delves into the theoretical advances that have been made to predict cyberbullying perpetration. It examines myriad psychological- and communication-based theories, discusses the relevant research to support (or not) each theory, and elucidates the strengths and limitations of these theories. Moreover, the book differentiates cyberbullying from traditional bullying to expand on a theory that takes such differences into account to predict perpetration. In addition, it adapts interventions to address these nuanced theoretical advancements and concludes with an examination of validated psychological theories that can inform interventions and reduce cyberbullying. The book is an effective and concise reference for psychologists, school administrators, counselors and psychological researchers looking to understand theory and interventions for cyberbullies. 172 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There are three universal experiences that we cannot escape: loneliness, illness, and death. The Psychological Journey To and From Loneliness addresses what was termed the plague of the 21st century--loneliness. Loneliness is stigmatized in our society, so untold number of people walk around lonely, unable to do what is so naturally called for--make their suffering known, and approach others for company and support. Thankfully, loneliness is slowly, but steadily, coming out of the 'closet.' This book will highlight not only the experience and what can be done about it, but also the experiences that influence it (i.e., our childhood, cultural and religious influences, and our way of life) as well as the effects that loneliness has on various population groups and how it is experienced at different times in our lives. This volume reviews theoretical approaches to the study of loneliness: the (positive) functions that loneliness may serve in our lives; the stages in life when loneliness is quite 'visible' and its effects on us; the life experiences that may strengthen the feeling that one is all alone and forgotten; life experiences that we do not commonly connect to loneliness but it is clearly present in them (e.g., pregnancy and childbirth); and the approaches that are available to copy with its pain and limit its negative effects on us. The book closes with a review of how psychotherapy can assist those who need encouragement and support in their struggle with loneliness. The book is particularly suitable for academics, researchers, and clinicians who aim to help clients identify, address, and cope with loneliness. 308 pp. Englisch.…