elsevier science nov 2005 (20 risultati)

Buch. Condizione: Neu. Neuware - As new techniques of transferring from liquid to gas phase and measuring masses of drug molecules and metabolites become more prevalent, so do the technical challenges of putting these techniques into proper use, as well as the task of consolidating emerging applications. Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS, Volume 6 fills the gap in the lack of presently available literature by providing a critical review in the current use of liquid chromatography-mass spectrometry (LC-MS) in drug discovery and development. With chapters written by experts with a wide range of practical experience from the pharmaceutical industry, emphasis is placed on techniques and applications. The book also includes chapters on how to utilize LC-MS instrumentation for current drug metabolism problems. This book is intended for those beginning to use LC-MS for drug metabolism studies as well as for those considered advanced practitioners.

Buch. Condizione: Neu. Neuware - Bonding Theory for Metals and Alloys exhorts the potential existence of covalent bonding in metals and alloys. Through the recognition of the covalent bond in coexistence with the 'free' electron band, the book describes and demonstrates how the many experimental observations on metals and alloys can all be reconciled. Subsequently, it shows how the individual view of metals and alloys by physicists, chemists and metallurgists can be unified. The physical phenomena of metals and alloys covered in this book are: Miscibility Gap between two liquid metals; Phase Equilibrium Diagrams; Phenomenon of Melting. Superconductivity; Nitinol; A Metal-Alloy with Memory; Mechanical Properties; Liquid Metal Embrittlement; Superplasticity; Corrosion; The author introduces a new theory based on 'Covalon' conduction, which forms the basis for a new approach to the theory of superconductivity. This new approach not only explains the many observations made on the phenomenon of superconductivity but also makes predictions that have been confirmed.

Buch. Condizione: Neu. Neuware - Fuzzy set and logic theory suggest that all natural language linguistic expressions are imprecise and must be assessed as a matter of degree. But in general membership degree is an imprecise notion which requires that Type 2 membership degrees be considered in most applications related to human decision making schemas. Even if the membership functions are restricted to be Type1, their combinations generate an interval - valued Type 2 membership. This is part of the general result that Classical equivalences breakdown in Fuzzy theory. Thus all classical formulas must be reassessed with an upper and lower expression that are generated by the breakdown of classical formulas.

Buch. Condizione: Neu. Neuware - Neutron Scattering from Magnetic Materials is a comprehensive account of the present state of the art in the use of the neutron scattering for the study of magnetic materials. The chapters have been written by well-known researchers who are at the forefront of this field and have contributed directly to the development of the techniques described. Neutron scattering probes magnetic phenomena directly. The generalized magnetic susceptibility, which can be expressed as a function of wave vector and energy, contains all the information there is to know about the statics and dynamics of a magnetic system and this quantity is directly related to the neutron scattering cross section. Polarized neutron scattering techniques raise the sophistication of measurements to even greater levels and gives additional information in many cases. The present book is largely devoted to the application of polarized neutron scattering to the study of magnetic materials. It will be of particular interest to graduate students and researchers who plan to investigate magnetic materials using neutron scattering.

Buch. Condizione: Neu. Neuware - The aim of this Handbook is to acquaint the reader with the current status of the theory of evolutionary partial differential equations, and with some of its applications. Evolutionary partial differential equations made their first appearance in the 18th century, in the endeavor to understand the motion of fluids and other continuous media. The active research effort over the span of two centuries, combined with the wide variety of physical phenomena that had to be explained, has resulted in an enormous body of literature. Any attempt to produce a comprehensive survey would be futile. The aim here is to collect review articles, written by leading experts, which will highlight the present and expected future directions of development of the field. The emphasis will be on nonlinear equations, which pose the most challenging problems today.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The sexy, elegant design of the Apple PowerBook combined with the Unix-like OS X operating system based on FreeBSD, have once again made OS X the Apple of every hacker's eye. In this unique and engaging book covering the brand new OS X 10.4 Tiger, the world's foremost 'true hackers? unleash the power of OS X for everything form cutting edge research and development to just plain old fun.OS X 10.4 Tiger is a major upgrade for Mac OS X for running Apple's Macintosh computers and laptops. This book is not a reference to every feature and menu item for OS X. Rather, it teaches hackers of all types from software developers to security professionals to hobbyists, how to use the most powerful (and often obscure) features of OS X for wireless networking, WarDriving, software development, penetration testing, scripting administrative tasks, and much more. 512 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Sarbanes-Oxley Act is a mandatory requirement for all corporations listed in the US. Compliance is not an option. This book is written as a 'working manual? for the senior management to grasp the Act and its implications. It provides a section by section overview of the Act and the appropriate action to take in each case. There is coverage of how UK companies listed in, or doing business with America also have to comply with the Sarbanes-Oxley Act. A description of the UK version of SOX is also included. The Appendix describes the (minor) variations for Canadian listed corporations based on Ontario Securities Commission and British Columbia Securities Commission rules. 160 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Numerical Modeling in Biomedical Engineering brings together the integrative set of computational problem solving tools important to biomedical engineers. Through the use of comprehensive homework exercises, relevant examples and extensive case studies, this book integrates principles and techniques of numerical analysis. Covering biomechanical phenomena and physiologic, cell and molecular systems, this is an essential tool for students and all those studying biomedical transport, biomedical thermodynamics & kinetics and biomechanics. 640 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Shutdown management is project management of a special kind: managing the repair, replacement or maintenance of critical systems. Manufacturing and process plants, computer systems, airliners, and many other systems must be regularly closed down or taken out of service for planned maintenance operations. This book provides a complete shutdown project planning guide along with a new, detailed model of excellence and step-by-step project guide. In a critical field, this book shows the maintenance manager or project leader how to get the job done correctly. 256 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is dedicated to the multiple aspects, that is, biological, physical and computational of DNA and RNA molecules. These molecules, central to vital processes, have been experimentally studied by molecular biologists for five decades since the discovery of the structure of DNA by Watson and Crick in 1953. Recent progresses (e.g. use of DNA chips, manipulations at the single molecule level, availability of huge genomic databases.) have revealed an imperious need for theoretical modelling. Further progresses will clearly not be possible without an integrated understanding of all DNA and RNA aspects and studies.The book is intended to be a desktop reference for advanced graduate students or young researchers willing to acquire a broad interdisciplinary understanding of the multiple aspects of DNA and RNA. It is divided in three main sections:The first section comprises an introduction to biochemistry and biology of nucleic acids. The structure and function of DNA are reviewed in R. Lavery's chapter. The next contribution, by V. Fritsch and E. Westhof, concentrates on the folding properties of RNA molecules. The cellular processes involving these molecules are reviewed by J. Kadonaga, with special emphasis on the regulation of transcription. These chapters does not require any preliminary knowledge in the field (except that of elementary biology and chemistry).The second section covers the biophysics of DNA and RNA, starting with basics in polymer physics in the contribution by R. Khokhlov. A large space is then devoted to the presentation of recent experimental and theoretical progresses in the field of single molecule studies. T. Strick's contribution presents a detailed description of the various micro-manipulation techniques, and reviews recent experiments on the interactions between DNA and proteins (helicases, topoisomerases, .). The theoretical modeling of single molecules is presented by J. Marko, with a special attention paid to the elastic and topological properties of DNA. Finally, advances in the understanding of electrophoresis, a technique of crucial importance in everyday molecular biology, are exposed in T. Duke's contribution.The third section presents provides an overview of the main computational approaches to integrate, analyse and simulate molecular and genetic networks. First, J. van Helden introduces a series of statistical and computational methods allowing the identification of short nucleic fragments putatively involved in the regulation of gene expression from sets of promoter sequences controlling co-expressed genes. Next, the chapter by Samsonova et al. connects this issue of transcriptional regulation with that of the control of cell differentiation and pattern formation during embryonic development. Finally, H. de Jong and D. Thieffry review a series of mathematical approaches to model the dynamical behaviour of complex genetic regulatory networks. This contribution includes brief descriptions and references to successful applications of these approaches, including the work of B. Novak, on the dynamical modelling of cell cycle in different model organisms, from yeast to mammals. 378 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The book introduces a hot topic of novel and emerging computing paradigms and architectures -computation by travelling waves in reaction-diffusion media. A reaction-diffusion computer is a massively parallel computing device, where the micro-volumes of the chemical medium act as elementary few-bit processors, and chemical species diffuse and react in parallel. In the reaction-diffusion computer both the data and the results of the computation are encoded as concentration profiles of the reagents, or local disturbances of concentrations, whilst the computation per se is performed via the spreading and interaction of waves caused by the local disturbances. The monograph brings together results of a decade-long study into designing experimental and simulated prototypes of reaction-diffusion computing devices for image processing, path planning, robot navigation, computational geometry, logics and artificial intelligence. The book is unique because it gives a comprehensive presentation of the theoretical and experimental foundations, and cutting-edge computation techniques, chemical laboratory experimental setups and hardware implementation technology employed in the development of novel nature-inspired computing devices.Key Features:- Non-classical and fresh approach to theory of computation.- In depth exploration of novel and emerging paradigms of nature-inspired computing.- Simple to understand cellular-automata models will help readers/students to design their own computational experiments to advance ideas and concepts described in the book .- Detailed description of receipts and experimental setups of chemical laboratory reaction-diffusion processors will make the book an invaluable resource in practical studies of non-classical and nature-inspired computing architectures .- Step by step explanations of VLSI reaction-diffusion circuits will help students to design their own types of wave-based processors. 348 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Proceedings of the 20th International Cryogenic Engineering Conference 1092 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 3 looks at classes of biomolecules including carbohydrates, nucleic acids, and lipids. In addition, special areas of application are included, such as pharmaceuticals, natural products, isotope ratio methods for biomolecules analysis, and clinical applications. The articles are arranged under general headings for continuity and ease of access, although several of these are of interest across the various disciplines. The articles are intended to teach and therefore strive to cover basics and sufficient additional detail to bring the reader up-to-date on a given subject. Some advanced topics are also covered, either in a special section of articles or in additional reading citations. 600 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medical textiles are a major growth area within the technical textiles industry and the range of applications continues to grow and increase in diversity with every new development. Recent innovations include novel chitosan-alginate fibres for advanced wound dressings, ultrasonic energy for bleaching cotton medical textiles, durable and rechargeable biocidal textiles, spider silk supportive matrix for cartilage regeneration, barbed bi-directional surgical sutures and intelligent textiles for medical applications.Medical textiles and biomaterials for healthcare is a culmination of the worldwide research into medical textiles and biomaterials. It is divided into eight parts covering the main areas of basic biomaterials, healthcare and hygiene products, infection control and barrier materials, bandaging and pressure garments, woundcare materials, implantable and medical devices and smart technologies. Each part contains a comprehensive overview written by leading experts in the area. The overviews are then followed by a selection of the best papers from the 2003 MEDTEX Conference, hosted by the University of Bolton. It has been extensively edited to produce what is expected to be the leading reference on this subject. 520 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Solid/fluid separation is a major element in the processes performed in pharmaceutical, food, beverage, water, pulp and paper industries. Several books now exist on the more esoteric aspects of the techniques, but accounts of the fundemental principles involved are few. Written by two well-known chemical engineers, this book reviews the scientific and engineering bases for solid/fluid separation processes in an approachable style. Coverage focuses on fluid dynamics, gravity, centrifugal and membrane separations, filter cake formation, de-liquoring and washing. Complete with an extensive bibliography to allow readers to pursue topics in greater depth. 340 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Maria Sala introduced experimental and field-based studies on soil and fluvial processes in Spain during the late 1970s and early 1980s. Research on this broad topic has grown remarkably worldwide since then. This title shows some of these advances and documents the latest research, although with a particularity: it gives special treatment to research on Mediterranean climate regions, an ever-present issue in Maria Sala's research career. It contains the latest research on slope and river processes with a special emphasis on rivers and catchments with a Mediterranean climate. Papers cover a gamut of topics describing research and applied studies, mainly in Spain, but also in Israel, the USA, Canada, the UK and New Zealand. The book examines natural and anthropogenic processes operating in drainage basins and includes coverage of current experimental and fieldwork investigations on soil erosion, river and catchment hydrology, suspended sediment transport and bedload dynamics in gravel-bed rivers, and present-day diagnosis and future key-paths for catchment and river management. 246 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The 1st International Meeting on Applied Physics (APHYS-2003) succeeded in creating a new international forum for applied physics in Europe, with specific interest in the application of techniques, training, and culture of physics to research areas usually associated with other scientific and engineering disciplines.This book contains a selection of peer-reviewed papers presented at APHYS-2003, held in Badajoz (Spain), from 15th to 18th October 2003, which included the following Plenary Lectures:\* Nanobiotechnology - Interactions of Cells with Nanofeatured Surfaces and with Nanoparticles\* Radiation Protection of Nuclear Workers - Ethical Issues\* Chaotic Data Encryption for Optical Communications 600 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cyclic Development of Sedimentary Basins presents the controversial subject of the cyclic phenomena in the earth's evolutionary history and its reflection in the development of sedimentary basins and its lithic infillings. Galactic rotation of celestial bodies causes cyclicity that is also reflected on a smaller scale in the proper Earth. This book presents the consequences of the earth's cyclic phenomena in the long-term cycles which affect the origin and further evolution of sedimentary basins. 530 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Budgets are like road maps -- they provide a direction for a corporates financial management. Balance sheets and statements of revenues also provide insights into how well a company is following that direction. But cash flow and cash flow forecasts are what guide the day-to-day itinerary for an organization. Budgets and cash flow are dynamic -- adjustments and changes can and should occur. If you understand what you are looking at, you can use cash flow to create better budgets and thus more accurate cash flow forecasting.Cash Flow Forecasting outlines the techniques required to undertake a detailed analysis of the cash flow dynamics of the business from both a historical and forward looking perspective. Cash Flow Forecasting explains how to: \* Determine appropriate cash flow figures from pro forma financial statements \* Interpret detailed cash flow forecasts and understand the difference between profit and cash flow \* Conserve or generate cash in the short term \* Evaluate different methods of project evaluation \* Recognize the limitations of accounting information in valuing companies 256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Given the vast amount of research related to behavioral assessment, it is difficult for clinicians to keep abreast of new developments. In recent years, there have been advances in assessment, case conceptualization, treatment planning, treatment strategies for specific disorders, and considerations of new ethical and legal issues. Keeping track of advances requires monitoring diverse resources limited to specific disorders, many of which are theoretical rather than practical, or that offer clinical advice without providing the evidence base for treatment recommendations. This handbook was created to fill this gap, summarizing critical information for adult behavioral assessment. The Clinician's Handbook of Adult Behavioral Assessment provides a single source for understanding new developments in this field, cutting across strategies, techniques, and disorders. Assessment strategies are presented in context with the research behind those strategies, along with discussions of clinical utility, and how assessment and conceptualization fit in with treatment planning. The volume is organized in three sections, beginning with general issues, followed by evaluations of specific disorders and problems, and closing with special issues. To ensure cross chapter consistency in the coverage of disorders, these chapters are formatted to contain an introduction, assessment strategies, research basis, clinical utility, conceptualization and treatment planning, a case study, and summary. Special issue coverage includes computerized assessment, evaluating older adults, behavioral neuropsychology, ethical-legal issues, work-related issues, and value change in adults with acquired disabilities. Suitable for beginning and established clinicians in practice, this handbook will provide a ready reference toward effective adult behavioral assessment. Englisch.