Humana aug 2008 (27 risultati)

Taschenbuch. Condizione: Neu. Neuware -One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems.…

Taschenbuch. Condizione: Neu. Neuware - One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems.…

Taschenbuch. Condizione: Neu. Neuware -One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems. 272 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Jupiter's ice moon Europa is widely regarded as the most likely place to find accessible extraterrestrial life. This book tells the engaging story of Europa, the oceanic moon. It features a large number of stunning images of the ocean moon's surface, clearly displaying the spectacular crack patterns, extensive rifts and ridges, and refrozen pools of exposed water filled with rafts of displaced ice. Coverage also features firsthand accounts of Galileo's mission to Jupiter and its moons. The book tells the rough and tumble inside story of a very human enterprise in science that lead to the discovery of a fantastic new world that might well harbor life. 296 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Jupiter's ice moon Europa is widely regarded as the most likely place to find extraterrestrial life. This book tells the engaging story of Europa, the oceanic moon. It features a large number of stunning images of the ocean moon¿s surface, clearly displaying the spectacular crack patterns, extensive rifts and ridges, and refrozen pools of exposed water filled with rafts of displaced ice. Coverage also features firsthand accounts of Galileös mission to Jupiter and its moons. The book tells the rough and tumble inside story of a very human enterprise in science that lead to the discovery of a fantastic new world that might well harbor life.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 296 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems. 272 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems. 272 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Due to the vital biological importance of RNA and proteins functioning together within a cell, a protocol volume describing experimental procedures to study their interactions should find a home in many laboratories. RNA-Protein Interaction Protocols, Second Edition updates, complements, and expands upon the popular first edition by providing a collection of cutting-edge techniques developed or refined in the past few years along with tried-and-true methods. The expert contributors explore the isolation and characterization of RNA-protein complexes, the analysis and measurement of RNA-protein interaction, and related novel techniques and strategies. Written in the highly successful Methods in Molecular Biology(TM) series format, the chapters include brief introductions to the material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlights tips on troubleshooting and avoiding known pitfalls.Comprehensive and up-to-date, RNA-Protein Interaction Protocols, Second Edition is an ideal guide for researchers continuing the study of this all-important biological partnership. 436 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although our understanding of the structure and activities of the cell nucleus and of the nanomachines which it contains is increasing rapidly, much remains to be learned. The application and continuing development of the new, powerful biochemical and biophysical methodologies described hereare essential in this quest. In The Nucleus, researchers from more than forty leading international laboratories describe state-of-the-art methods for isolating nuclei and their components and for studying their structure and activities, including some pathology-associated features. Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imagingpresentsbiophysical approaches to study the mechanical properties of nuclei, together with a comprehensive range of imaging methods. These include FISH, FRAP, FRET, molecular beacons, fluorescence correlation spectroscopy, single molecule tracking, and combing DNA for optical microscopy, recognition imaging for atomic force microscopy, and hybridisation, tomography, and spectroscopic imaging for electron microscopy. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain lists of necessary materials and reagents, readily reproducible protocols, and tips for troubleshooting and avoiding known pitfalls.The Nucleus, Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging provides a comprehensive collection of the cutting-edge methods making a major contribution to understanding the nucleus and its nanostructure today. 472 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although our understanding of the structure and activities of the cell nucleus and of the nanomachines which it contains is increasing rapidly, much remains to be learned. The application and continuing development of the new, powerful biochemical and biophysical methodologies described here are essential in this quest. In The Nucleus, researchers from more than forty leading international laboratories describe state-of-the-art methods for isolating nuclei and their components and for studying their structure and activities, including some pathology-associated features. Volume I: Nuclei and Subnuclear Structures presents an overview of features of the intranuclear environment, followed by the most recent procedures for isolating nuclei from a wide range of cell types including muscle cells, yeast, oocytes, cells with polytene nuclei, Arabidopsis, trypanosomes, and dinoflagellates. The latest methods are described for isolating and working with nucleoli, constitutive heterochromatin, pathology-associated inclusions, and chromatin and for examining glycosylation, sumoylation, and ADP-ribosylation of nuclear proteins. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain lists of necessary materials and reagents, readily reproducible protocols, and tips for troubleshooting and avoiding known pitfalls.The Nucleus, Volume I: Nuclei and Subnuclear Structures is an essential reference for scientists who are working on our rapidly growing understanding of the cell nucleus and its activities. 352 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular Biology(TM) series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results.Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead. 284 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -One of the 'image' problems with wavelets is that because they have been a dominant area of interest (in nonparametric smoothing) people have forgotten that they are general tools with a fascinating role and future in other areas. This book describes new topics and presents multiscale as a unifying force able to be used in many different kinds of interesting problems.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 272 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics. These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods. Techniques covered range from traditional multivariate methods, such as multiple regression, principal components, canonical variates, linear discriminant analysis, factor analysis, clustering, multidimensional scaling, and correspondence analysis, to the newer methods of density estimation, projection pursuit, neural networks, multivariate reduced-rank regression, nonlinear manifold learning, bagging, boosting, random forests, independent component analysis, support vector machines, and classification and regression trees. Another unique feature of this book is the discussion of database management systems.This book is appropriate for advanced undergraduate students, graduate students, and researchers in statistics, computer science, artificial intelligence, psychology, cognitive sciences, business, medicine, bioinformatics, and engineering. Familiarity with multivariable calculus, linear algebra, and probability and statistics is required. The book presents a carefully-integrated mixture of theory and applications, and of classical and modern multivariate statistical techniques, including Bayesian methods. There are over 60 interesting data sets used as examples in the book, over 200 exercises, and many color illustrations and photographs. 760 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Although our understanding of the structure and activities of the cell nucleus and of the nanomachines which it contains is increasing rapidly, much remains to be learned. The application and continuing development of the new, powerful biochemical and biophysical methodologies described here are essential in this quest. In The Nucleus, researchers from more than forty leading international laboratories describe state-of-the-art methods for isolating nuclei and their components and for studying their structure and activities, including some pathology-associated features. Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging presents biophysical approaches to study the mechanical properties of nuclei, together with a comprehensive range of imaging methods. These include FISH, FRAP, FRET, molecular beacons, fluorescence correlation spectroscopy, single molecule tracking, and combing DNA for optical microscopy, recognition imaging for atomic force microscopy, and hybridisation, tomography, and spectroscopic imaging for electron microscopy. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain lists of necessary materials and reagents, readily reproducible protocols, and tips for troubleshooting and avoiding known pitfalls.The Nucleus, Volume 2: Chromatin, Transcription, Envelope, Proteins, Dynamics, and Imaging provides a comprehensive collection of the cutting-edge methods making a major contribution to understanding the nucleus and its nanostructure today.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 472 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Although our understanding of the structure and activities of the cell nucleus and of the nanomachines which it contains is increasing rapidly, much remains to be learned. The application and continuing development of the new, powerful biochemical and biophysical methodologies described here are essential in this quest. In The Nucleus, researchers from more than forty leading international laboratories describe state-of-the-art methods for isolating nuclei and their components and for studying their structure and activities, including some pathology-associated features. Volume I: Nuclei and Subnuclear Structures presents an overview of features of the intranuclear environment, followed by the most recent procedures for isolating nuclei from a wide range of cell types including muscle cells, yeast, oocytes, cells with polytene nuclei, Arabidopsis, trypanosomes, and dinoflagellates. The latest methods are described for isolating and working with nucleoli, constitutive heterochromatin, pathology-associated inclusions, and chromatin and for examining glycosylation, sumoylation, and ADP-ribosylation of nuclear proteins. Written in the highly successful Methods in Molecular Biology¿ series format, chapters contain lists of necessary materials and reagents, readily reproducible protocols, and tips for troubleshooting and avoiding known pitfalls.The Nucleus, Volume I: Nuclei and Subnuclear Structures is an essential reference for scientists who are working on our rapidly growing understanding of the cell nucleus and its activities.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 352 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -As one of the fastest growing fields of research in the 21st century, nanotechnology is sure to have an enormous impact on many aspects of our lives. Nanostructure Design: Methods and Protocols serves as a major reference for theoretical and experimental considerations in the design of biological and bio-inspired building blocks, the physical characterization of the formed structures, and the development of their technical applications. The chapters contributed by leading experts are divided into two sections, the first of which covers experimental aspects of nanostructure design and the second delves into computational methods. As a volume of the highly successful Methods in Molecular Biology¿ series, this collection pulls together cutting-edge protocols, written in a step-by-step, readily reproducible format certain to guide researchers to the desired results.Comprehensive and essential, Nanostructure Design: Methods and Protocols uses biological principles and vehicles on design to aid scientists in the great challenges still ahead.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -As membrane trafficking research has expanded, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes. These protocols have been tested in laboratories all around world. As a volume of the highly successful Methods in Molecular Biology(TM) series, the chapters include step-by-step laboratory protocols, a list of necessary materials and reagents, and the greatly beneficial Notes section, which aids in troubleshooting and avoiding known pitfalls. Comprehensive and state-of-the-art, this is the ideal reference for both senior researchers experienced in the field and graduate students studying membrane trafficking for the first time.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 424 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Due to the vital biological importance of RNA and proteins functioning together within a cell, a protocol volume describing experimental procedures to study their interactions should find a home in many laboratories. RNA-Protein Interaction Protocols, Second Edition updates, complements, and expands upon the popular first edition by providing a collection of cutting-edge techniques developed or refined in the past few years along with tried-and-true methods. The expert contributors explore the isolation and characterization of RNA-protein complexes, the analysis and measurement of RNA-protein interaction, and related novel techniques and strategies. Written in the highly successful Methods in Molecular Biology¿ series format, the chapters include brief introductions to the material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlights tips on troubleshooting and avoiding known pitfalls.Comprehensive and up-to-date, RNA-Protein Interaction Protocols, Second Edition is an ideal guide for researchers continuing the study of this all-important biological partnership.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -¿Look deep into nature and you will understand everything better.¿ advised Albert Einstein. In recent years, the research communities in Computer Science, Engineering, and other disciplines have taken this message to heart, and a relatively new field of ¿biologically-inspired computing¿ has been born. Inspiration is being drawn from nature, from the behaviors of colonies of ants, of swarms of bees and even the human body. This new paradigm in computing takes many simple autonomous objects or agents and lets them jointly perform a complex task, without having the need for centralized control. In this paradigm, these simple objects interact locally with their environment using simple rules. Applications include optimization algorithms, communications networks, scheduling and decision making, supply-chain management, and robotics, to name just a few. There are many disciplines involved in making such systems work: from artificial intelligence to energy aware systems. Often these disciplines have their own field of focus, have their own conferences, or only deal with specialized s- problems (e.g. swarm intelligence, biologically inspired computation, sensor networks). The Second IFIP Conference on Biologically-Inspired Collaborative Computing aims to bridge this separation of the scientific community and bring together researchers in the fields of Organic Computing, Autonomic Computing, Self-Organizing Systems, Pervasive Computing and related areas. We are very pleased to have two very important keynote presentations: Swarm Robotics: The Coordination of Robots via Swarm Intelligence Principles by Marco Dorigo (Université Libre de Bruxelles, Belgium), of which an abstract is included in this volume.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 260 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Remarkable advances in computation and data storage and the ready availability of huge data sets have been the keys to the growth of the new disciplines of data mining and machine learning, while the enormous success of the Human Genome Project has opened up the field of bioinformatics.These exciting developments, which led to the introduction of many innovative statistical tools for high-dimensional data analysis, are described here in detail. The author takes a broad perspective; for the first time in a book on multivariate analysis, nonlinear methods are discussed in detail as well as linear methods. Techniques covered range from traditional multivariate methods, such as multiple regression, principal components, canonical variates, linear discriminant analysis, factor analysis, clustering, multidimensional scaling, and correspondence analysis, to the newer methods of density estimation, projection pursuit, neural networks, multivariate reduced-rank regression, nonlinear manifold learning, bagging, boosting, random forests, independent component analysis, support vector machines, and classification and regression trees. Another unique feature of this book is the discussion of database management systems.This book is appropriate for advanced undergraduate students, graduate students, and researchers in statistics, computer science, artificial intelligence, psychology, cognitive sciences, business, medicine, bioinformatics, and engineering. Familiarity with multivariable calculus, linear algebra, and probability and statistics is required. The book presents a carefully-integrated mixture of theory and applications, and of classical and modern multivariate statistical techniques, including Bayesian methods. There are over 60 interesting data sets used as examples in the book, over 200 exercises, and many color illustrations and photographs.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 760 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A decline in populations of Allegheny woodrats (Neotoma magister) was first noticed in the 1980s. Since that time, woodrats have become extirpated from at least two states and have declined dramatically in several others. Recent evidence suggests that the decline of this species may be proceeding further south to include states where woodrat populations were previously considered to be stable.The Allegheny Woodrat: Ecology, Conservation, and Management of a Declining Species provides a comprehensive summary of research conducted over the past twenty-five years. The book integrates the results of this research into a comprehensive picture of the ecological requirements, conservation principles, and management strategies for this declining species. In addition, general principles learned from the study of woodrats are applied to the conservation and management of other declining species, including other species of Neotoma.The editors and chapter authors are researchers from both academic settings and state management agencies, individuals who have contributed significantly to the study of Allegheny woodrats during the past two decades. The book will be of interest to ecologists, conservation biologists, wildlife professionals, and students.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases. Since the identification of this unique member of the Cdk family, Cdk5 has emerged as one of the most important signal transduction mediators in the development, maintenance and fine-tuning of neuronal functions and networking. Further studies have revealed that Cdk5 is also associated with the regulation of neuronal survival during both developmental stages and in neurodegenerative diseases. These observations indicate that precise control of Cdk5 is essential for the regulation of neuronal survival. The pivotal role Cdk5 appears to play in both the regulation of neuronal survival and synaptic functions thus raises the interesting possibility that Cdk5 inhibitors may serve as therapeutic treatment for a number of neurodegenerative diseases.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. This book expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Written by a well-established panel of research scientists, the book provides an up-to-date collection of methods used regularly in the authors' own research programs. 1148 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths. Comprehensive and penetrating, the book brings together the mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system. 524 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -t this will enable readers to acquire an appreciationof this developmentalprocess in all its facets.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 212 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. Molecular Biomethods Handbook, 2nd Edition expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Part A of the book describes nucleic acid methods, such as gene expression profiling, microarray analysis and quantitative PCR. In Part B, protein and cell-based methods are outlined, in subjects ranging from protein engineering to high throughput screening. Written by a well-established panel of research scientists, Molecular Biomethods Handbook, 2nd Edition provides an up to date collection of methods used regularly in the authors¿ own research programs. This book will prove to be an invaluable reference for those engaged in or entering the field of molecular biology, and will provide the necessary background for those interested in setting up and using the latest molecular techniques.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1148 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Remarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, The Visual Transduction Cascade: Basic and Clinical Principles reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths -- a good example of the limitations of the human sensory systems. Comprehensive and penetrating, The Visual Transduction Cascade: Basic and Clinical Principles brings together the developmental, structural, and molecular mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 524 pp. Englisch.…