humana jul 2012 (153 risultati)

Taschenbuch. Condizione: Neu. Neuware -In a state-of-the-art synthesis of basic science and clinical practice, Roy Smith and a distinguished panel of researchers and clinicians review GH regulation and its action at the molecular level, and describe the basis for GH deficiency and the use of GH as therapy in a variety of clinical situations. The clinical presentation moves beyond the treatment of GH-deficient children to include the genetics of GH-deficiency, GH-deficiency in adults, osteoporosis, Syndrome X, sleep quality, GH in AIDS patients, GHRH in clinical studies. Timely and innovative, Human Growth Hormone: Research and Clinical Practice will benefit both basic and clinical researchers, as well as those clinical endocrinologists who want to use growth hormone not only in treating children, but also in treating adult disorders, including those associated with metabolic disease. 360 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware - Maybe you'll be glad Uncle Will wasn't your best friend, but you will be glad you've read about Uncle Will and his exploits. We're talking about someone whose funeral was attended by people who mostly just wanted to make sure he was dead: Even the preacher couldn't cook up a decent eulogy! Oh, Uncle Will was a character, all right. His specialties: lyin', cheatin', gamblin', drinkin', and good livin'. And, in his own way, lovin'.The Devil and Uncle Will immortalizes many of the unforgettable adventures and stories Harold Miles heard from Uncle Will himself. Written with a special fondness for the old reprobate, The Devil and Uncle Will brings to life an extraordinary character-someone who actually claimed he'd made a pact with the devil. Latter-day Faust, good-ol'-boy gone bad-that's Uncle Will.Harold Miles' style is lively, poignant, captivating. He knew and loved-and often found it hard to love-Uncle Will. Heck, he's kinfolk. But though there's an underlying deep seriousness in The Devil and Uncle Will, it's also an extremely funny book-southern humor at its best.You'll laugh out loud, smile, maybe even shed a tear or two. But, whatever your emotions, you won't want to put this book down!

Buch. Condizione: Neu. Neuware - 'Modern Compiler Design' makes the topic of compiler design more accessible by focusing on principles and techniques of wide application. By carefully distinguishing between the essential (material that has a high chance of being useful) and the incidental (material that will be of benefit only in exceptional cases) much useful information was packed in this comprehensive volume. The student who has finished this book can expect to understand the workings of and add to a language processor for each of the modern paradigms, and be able to read the literature on how to proceed. The first provides a firm basis, the second potential for growth.

Taschenbuch. Condizione: Neu. Neuware - Clinical experts synthesize for the practicing physician all the important developments that have occurred recently in the diagnosis and treatment of acid-related diseases. They address the evaluation of patients suspected of harboring both peptic ulcers and ulcers from other causes, with emphasis on novel aspects of H. pylori infection. New information is also provided to assist clinicians in efficiently managing patients with dyspepsia and in the diagnosis and treatment of gastroesophageal reflux disease (GERD), including its extraesophageal manifestations and upper gastrointestinal bleeding. Authoritative and highly readable, Diseases of the Gastroesophageal Mucosa: The Acid-Related Disorders distills a wealth of cutting-edge clinical practice into one readable volume that will help every clinician manage patients with today's best diagnostic and treatment practice.

Taschenbuch. Condizione: Neu. Neuware - There has been a resurgence in stereotactic surgery for the treatment of Parkinson's disease, tremor, and dystonia, and with it a growing need for up-to-date information about these procedures. In Surgical Treatment of Parkinson's Disease and Other Movement Disorders, a panel of highly experienced neurosurgeons, neurophysiologists, neuropsychologists, and neuroanatomists join forces to create an integrated, cutting-edge survey of all the methodologies necessary for successful surgical treatment. On the surgical side they review a variety of techniques for Parkinson's disease, including thalamotomy, pallidotomy and bilateral pallidotomy, subthalamotomy, pallidal and thalamic deep brain stimulation, and subthalamic deep brain stimulation. Surgical therapy for tremor and dystonia is also covered. On the patient side, the authors systematically examine the key issues involved in patient selection, patient assessment before and after surgery, brain target localization, and postoperative programming of brain stimulators. Comprehensive and authoritative, Surgical Treatment of Parkinson's Disease and Other Movement Disorders integrates the diverse techniques now available in this rapidly growing field to provide a practical guide to effective treatment of patients afflicted with these disorders.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Subject bibliography.- Active sensors,.- AND/OR graphs,.- Artificial intelligence,.- Artificial vision systems,.- Bilateral servo manipulators,.- CAD,.- CAD - the geometrical elements,.- Classification of robots,.- DC and stepper motors,.- Design of ortheses - continuous path control,.- Dynamics,.- Dynamics of AMS,.- End effectors: their design and operation,.- Feedback signals to the operator by computer,.- General,.- Heuristic graph searching,.- Human operator in the teleoperation system,.- Human sensing,.- Human vision,.- Image comprehension - understanding image representation data,.- Image representation,.- Industrial applications of teleoperation,.- Kinematics of AMS,.- Knowledge-based languages,.- Knowledge-based robots,.- Legged locomotion,.- Logic and programming,.- Mammalian touch sensors,.- Mechanical master-slave telemanipulators,.- Medical applications of teleoperation,.- Modelling,.- Modelling dynamic control,.- Modelling manipulators,.- Motorized telemanipulators with open-loop control,.- Multi-armed robots,.- Nuclear applications of teleoperation,.- Operator substitution function,.- Performance of teleoperation systems,.- Pneumatic and hydraulic actuators,.- Point to point control,.- Positional control,.- Precision and repeatability,.- Production-rule expert systems,.- Program generation,.- Programming languages,.- Proximity sensors,.- Robot arm architecture,.- Robot configurations,.- Robot control,.- Robot simulation using CAD,.- Search techniques,.- Space applications of teleoperation,.- Speed control,.- Stress sensors and stress control,.- Structure of robots,.- Tactile sensors,.- Task description,.- Task performance,.- Teleoperation and computer science,.- Teleoperation systems: general,.- Training,.- Transmission devices,.- Transmissionsystems,.- Transporters and vehicles,.- Underwater applications of teleoperation,.- Author index. 108 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the book are reported the main results presented at the Third International Workshop on Data Analysis in Astronomy, held at the EUore Majorana Center for Scientific Culture, Erice, Sicily, Italy, on June 20-27,1988. The Workshop was the natural evolution of the two previous ones. The main goal of the first edition (Erice 1984) was to start a scientific interaction between Astronomers and Computer Scientists. Aim of the second (Erice 1986) was to look at the progress in data analysis methods and dedicated hardware technology. Data analysis problems become harder whenever the data are poor in statistics or the signal is weak and embedded in structured background. Experiments collecting data of such a nature require new and non-standard methodologies. Possibilistic approaches could be merged with the statistical ones, in order to formalize all the knowledge used by the scientists to reach conclusions. Moreover, the last decade has been characterized by very fast developments of Intelligent Systems for data analysis (knowledge based systems, . ) that would be useful to support astronomers in complex decision making. For these reasons, the last edition of the workshop was intended to provide an overview on the state of the art in the data analysis methodologies and tools in the new frontieres of the astrophysics (y-astronomy, neutrino astronomy, gravitational waves, background radiation and extreme cosmic ray energy spectrum). The book is organized in two sections: - Data analysis methods and tools, - New frontieres in astronomy. 428 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1. 1 Power-dissipation trends in CMOS circuits Shrinking device geometry, growing chip area and increased data-processing speed performance are technological trends in the integrated circuit industry to enlarge chip functionality. Already in 1965 Gordon Moore predicted that the total number of devices on a chip would double every year until the 1970s and every 24 months in the 1980s. This prediction is widely known as 'Moore's Law' and eventually culminated in the Semiconductor Industry Association (SIA) technology road map [1]. The SIA road map has been a guide for the in dustry leading them to continued wafer and die size growth, increased transistor density and operating frequencies, and defect density reduction. To mention a few numbers; the die size increased 7% per year, the smallest feature sizes decreased 30% and the operating frequencies doubled every two years. As a consequence of these trends both the number of transistors and the power dissi pation per unit area increase.In the near future the maximum power dissipation per unit area will be reached. Down-scaling of the supply voltage is not only the most effective way to reduce power dissipation in general it also is a necessary precondition to ensure device reliability by reducing electrical fields and device temperature, to prevent device degradation. A draw-back of this solution is an increased signal propa gation delay, which results in a lower data-processing speed performance. 172 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph is the first of a series which is designed to present in depth timely reviews of subjects related to the blood. Insofar as each subject lends itself, the clinical aspects of each topic will be presented as fully as is appropriate, in addition to the basic features. As a consequence, the various monographs should be found useful not solely by hematologists. Depending on the nature of each topic, it is expected that these monographs will be found important by physiologists and specialists in fields other than hematology, as well as by scientists of very diverse interests. The present treatise illus trates this point. Doctors Garby and Meldon have brought together in a most useful way the spectacular advances which have been made in the last decade or two in a field of fundamental biologic impor tance. They have also brought to the discussion of this subject their own observations and interpretations as well as their profound understanding of the respiratory functions of the blood. Maxwell M. Wintrobe Salt Lake City, Utah v Preface This volume is an attempt to summarize the present state of know ledge of the respiratory functions of blood in health and disease. Though it deals fairly thoroughly with physicochemical aspects of the blood's gas transport properties and with the molecular chemis try of hemoglobin, its main emphasis is the gas transport function of the blood in vivo and modes of its disturbance in disease. 304 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the results of many years of investigations of pulse gas-discharge lasers carried out at the Optical Laboratory of the Lebedev Physics Institute in Moscow. The two papers report mainly experimental results obtained in studies of pulse lasers utilizing translations in metals (Isaev and Petrash) and electronic transitions in diatomic molecules (Kaslin and Petrash). Population inversion mechanisms and the principal properties of the lasers are considered. v CONTENTS Investigation of Pulse Gas-Discharge Lasers Utilizing Atomic Transitions A. A. Isaev and G. G. Petrash Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1l. Efficiency in a Gas-Discharge Laser. - . - - - . . . . . - - - . . - - . - . . - . - . - . 12. Review of the Literature - - - - - - - . - - - - - - . . - - . . . - - - - . - - - - . - . . . - 4 Chapter I. Kinetics of Output Power Saturation in a Three-Level System. - - - - - - - - 61. Level Populations and Saturated Power in a Three-Level System. - - - - - - - - 72. Absence of Decay of Laser Levels. - - - - - - . - - - - . - . - . - - - - - - - - - - - - - 83. Decay of Laser Levels by Emission of Spontaneous Radiation. - - - - . 200 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Apparatus for Recording Neutral Particles by Reference to Decay Gamma Quanta.- Magnetic Spectrometer for Charged Particles.- Experimental Method of Determining the Efficiency Function of an Apparatus Containing a Magnetic Spectrometer.- Positive Pion Stopping Detector.- Absolute Sensitivity of a Thick-Walled Graphite Ionization Chamber for 1-GeV Photons.- Statistics of Time Measurements Made by the Scintillation Method.- A Cathode Stage with Amplified Feedback and Its Applications.- Wilson Chamber for Studying Photomeson Processes.- Relative Monitor for a Wilson Chamber. 196 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The changes which have taken place in electronics are truly astonishing. It is difficult to believe that within a single lifespan we have come from the cat's whisker diode, via the thermionic valve, to the 256K random access memory and beyond. These developments would not have come about without an increased understanding of the physics and technology of the solid state. Although the progression from Planck's quantum postulate to single chip electronic systems within eighty years has resulted in an increased level of specialisation of the fields of knowledge, solid state nevertheless continues to be a cross-disciplinary subject. The design and fabrication of solid state devices involve large elements of chemistry, physics and materials science. However, books on the subject tend to be written by specialists in one or other area. Thus a physics-based text is likely to have more details on quantum theory than is necessary for a technologist. Similarly, texts which concentrate on devices and their applications frequently ignore the fundamental background which is vital for a true understanding. 172 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph represents the eighth sponsored by the International Society for Biochemical Endocrinology. The topics should be of interest to basic research scientists, medical practitioners, and students of repro ductive biology. It complements our monograph published in 1979 on Structure and Function of the Gonadotropins. The monograph is organized in ten topic areas relative to the general theme of reproduction and contraception. There are several chapters in each area. Obviously, all aspects of each area could not be covered. An attempt was made to seek interesting basic research ideas and concepts that might in the future be applicable to fertility regulation. The topics are: interactions in gonadotropin regulation; GnRH analogues as contra ceptive agents; receptors in cellular localization of hormones; uterine and mammary receptors; germ-cell regulation and secretory proteins; control mechanisms and metabolic regulations; hCG peptides and anti sera as antifertility agents; ieutinization, oocyte maturation, and early pregnancy; steroids and cell growth; and finally, prostaglandins and cell function. The studies encompass many disciplines and techniques in anatomy, physiology, biochemistry, and endocrinology in animals and humans, both in vitro and in vivo. A conference of contributors was held in Maine at the Asticou Inn in Northeast Harbor during the week of September 9-13, 1979. The chapters as written for the monograph were presented for discussion by the participants, who were selected for their knowledge of, and contri butions to, this area of scientific investigation. 760 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plant diseases and pests are a major constraint to agricultural production despite the various measures used to control them. Chemical control, although often e~~ective, may pose environmental hazards and is relatively expensive, especially in developing countries where it may be completely uneconomic. Control through genetically mediated resistance to diseases and pests, is both cheap and environmentally sa~e and at present most diseases and pests o~ staple ~ood crops are controlled through some form of resistance. One of the basic problems in the use of resistance is its ~re quent lack of durability; very often a type of resistance is used that 'breaks down' after a certain period. The temporary nature of this resistance, due to the development of new strains of pest or pathogen able to overcome it, has seriously hindered the improvement o~ the yield potential of many crops as a continuing effort is needed to replace old cultivars who resistance has failed, with new ones. Following Vanderplank's now classical publications (1963, 1968) which differentiated horizontal and vertical resistance, studies on several host-parasite systems have shown that di~ferent types of resistance can be distinguished genetically and epidemiologically, and on the ability o~ the pests or pathogens to adapt to them. A knowledge of how resistance operates at the population level has also opened up possibilities of 'managing' relatively simple resistance types in such a way that a stable host-pathogen system can be pro duced with a minimum of crop loss. 468 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Apollo was known for its engineering triumphs, but its success also came from a disciplined management style. This excellent account of one of the most important personalities in early American human spaceflight history describes for the first time how George E. Mueller, the system manager of the human spaceflight program of the 1960s, applied the SPO methodology and other special considerations such as 'all-up'testing, resulting in the success of the Apollo Program. Wernher von Braun and others did not readily accept such testing or Mueller's approach to system management, but later acknowledged that without them NASA would not have landed astronauts on the Moon by 1969. While Apollo remained Mueller's priority, from his earliest days at the agency, he promoted a robust post-Apollo Program which resulted in Skylab, the Space Shuttle and the International Space Station. As a result of these efforts, Mueller earned the sobriquet: 'the father of the space shuttle.' Following his success at NASA, Mueller returned to industry. Although he did not play a leading role in human spaceflight again, in 2011 the National Air and Space Museum awarded him their lifetime achievement trophy for his contributions. Following the contributions of George E. Mueller, in this unique book Arthur L. Slotkin answers such questions as: exactly how did the methods developed for use in the Air Force ballistic missile programs get modified and used in the Apollo Program How did George E. Mueller, with the help of others, manage the Apollo Program How did NASA centers, coming from federal agencies with cultures of their own, adapt to the new structured approach imposed from Washington George E. Mueller is the ideal central character for this book. He was instrumental in the creation of Apollo extension systems leading to Apollo, the Shuttle, and today's ISS and thus was a pivotal figure in early American human spaceflight history. 336 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book serves as an introduction to calculus on normed vector spaces at a higher undergraduate or beginning graduate level. The prerequisites include basic calculus and linear algebra, as well as a certain mathematical maturity. All the important topology and functional analysis topics are introduced where necessary.In its attempt to show how calculus on normed vector spaces extends the basic calculus of functions of several variables, this book is one of the few textbooks to bridge the gap between the available elementary texts and high level texts. The inclusion of many non-trivial applications of the theory and interesting exercises provides motivation for the reader. 264 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -¿Epistemic governance¿ refers to the cognitive and knowledge-related paradigms that underlie a social system. In this volume, the authors apply the concept to higher education. In a comprehensive review of recent literature, they define key terms and concepts, arguing that a good, effective and sustainable governance of higher education is not possible unless the epistemic structure and knowledge paradigms of higher education are addressed directly. Effective governance of academic institutions is particularly important, given their essential role in generating and disseminating knowledge. The authors consider the practical and policy implications of the epistemic approach for promoting quality assurance, quality enhancement, and quality management of higher education, and their impact on university administration and academic career development.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 92 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mark W. Schwartz Soon after we came into extensive meadows: and I was assured that those meadows continue for a hundred and fifty miles. being in winter drowned lands and marshes. By the dryness of the season they were now beautiful pastures, and here presented itself one of the most delightful prospects I have ever beheld; all low grounds being meadow, and without wood, and all of the high grounds being covered with trees and appearing like islands: the whole scene seemed an elysium. Capt. Thomas Morris. 1791 I am sitting in a 60-mile-an-hour bus sailing over a highway originally laid out for horse and buggy. The ribbon of concrete has been widened and widened until the field fences threaten to topple into the road cuts. In the narrow thread of sod between the shaved banks and the toppling fences grow the relics of what once was Illinois: the prairie.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 456 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The 1976 Cargese Summer Institute was devoted to the study of certain exciting developments in quantum field theory and critical phenomena. Its genesis occurred in 1974 as an outgrowth of many scientific discussions amongst the undersigned, who decided to form a scientific committee for the organization of the school. On the one hand, various workers in quantum field theory were continuing to make startling progress in different directions. On the other hand, many new problems were arising from these various domains. Thus we feIt that 1976 might be an appropriate occasion both to review recent developments and to encourage interactions between researchers from different backgrounds working on a common set of unsolved problems. An important aspect of the school, as it took place, was the participation of and stimulating interaction between such a broad spectrum of theorists. The central topics of the school were chosen from the areas of solitons, phase transitions, critical behavior, the renormalization group, gauge fields and the analysis of nonrenormalizable field theories. A noteworthy feature of these topics is the interpene tration of ideas from quantum field theory and statistical mechanics whose inherent unity is seen in the functional integral formulation of quantum field theory. The actual lectures were partly in the form of tutorials designed to familiarize the participants with re cent progress on the main topics of the school. Others were in the form of more specialized seminars reporting on recent research.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 488 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume contains the proceedings of the NATO Advanced Research Workshop on Band Structure Engineering in Semiconductor Microstructures held at Il Ciocco, Castelvecchio Pascali in Tuscany between 10th and 15th April 1988. Research on semiconductor microstructures has expanded rapidly in recent years as a result of developments in the semiconductor growth and device fabrication technologies. The emergence of new semiconductor structures has facilitated a number of approaches to producing systems with certain features in their electronic structure which can lead to useful or interesting properties. The interest in band structure engineering has stimd ated a variety of physical investigations and nove 1 device concepts and the field now exhibits a fascinating interplay betwepn pure physics and device technology. Devices based on microstruc tures are useful vehicles for fundamental studies but also new device ideas require a thorough understanding of the basic physics. Around forty researchers gathered at I1 Ciocco in the Spring of 1988 to discuss band structure engineering in semiconductor microstructures.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 404 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -'Ecobehavioral analysis', the merging of social ecological studies and J.R. Kantor's theory of interbehavioral psychology, was termed just over a decade ago. Since then, innovative trends emerging in the field of developmental disabilities warrant a comprehensive update. Ecobehavioral Analysis and Developmental Disabilities: The Twenty-First Century offers such an update of current research, as Dr. Stephen Schroeder compiles the work of twenty-one noted authorities in this volume. Each contributor discusses his/her research on a personal level, providing fresh insights into various aspects of the field. Experiential research ranging from the naturalistic observations of behavior-environment interactions in the classroom to ecobehavioral studies in pharmacotherapy is also presented.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 272 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -For many years ergonomists and human engineering specialists have made significant contributions to the solution of problems faced in the area of human labour and to the introduction of their research results and field experience into the process of equipment design. However, the rapid increase in complexity of equipment in use as well as in development demonstrates the necessity of broaden ing the point of view continuously. The workshop held in Munich from March 22nd to March 26th, 1982, was an excellent opportunity for the participants to discuss their respective interests and their interpretation of needs for future research. The workshop was sponsored by the Human Factors Special Programme Panel of the Scientific Affairs Division of NATO. This sponsorship, together with the helpful assistance rendered by Drs. Bayraktar, Kroemer, and Sanders, is gratefully acknowledged. This volume contains the papers presented during the workshop. All these papers are directly related to the general aim: the ex change of experience collected in the field of ergonomic data for equipment design on the one hand and the definition of unexplored areas on the other. It is hoped that this presentation will help to define future research methods in the area of ergonomic data and set into motion fruitful discussions on the validity of the data in use today.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 296 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In contrast to the pattern of long-standing occidental street gangs modelled in the North American paradigm, new-age gangs have appeared as loosely organized, with a high degree of interchangeability of their membership. Associated with this structural fluidity is an equally significant geographic mobility, which paradoxically does not appear to diminish the intensity of personal bonds formed within and between ¿new-age¿ gangs. The dimensions of fluidity of gang membership and geographic mobility across police jurisdictions is increasingly seen as the organizational pattern of emerging gangs, in large part shaped by worldwide patterns of human migration and globalization. While the structure of new-age gangs appears as loose-knit, what must be emphasized is that this characteristic is reflective of a criminal network of economic commodity-based ¿turf¿ as opposed to a close-knit geographically anchored ¿turf¿ that has characterized the prevailing North American (occidental) gang model. This volume illuminates the structure and organization of increasingly emergent, fluid and mobile, new-age gangs within the context of transnational networks. The implications for law enforcement agencies is two-fold: i) the fluidity of new-age gang players challenges investigative techniques that remain predicated on suspect recognition through modus operandi repetition by those involved, and; ii) the movement of new-age gang players across police jurisdictions challenges the sharing of police information. This innovative work will be of interest to researchers in Criminology and Criminal Justice, as well as related disciplines including Sociology and Anthropology studying gangs and group-organization. It has strong implications for practitioners and professionals working in law enforcement, public policy, or with at-risk youth/young adults.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 68 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mapping of Chemical Data Bases Using a Relational Data Base Structure.- Computer Aided Design of Experiments and Automatic Data Processing.- Computer Based Teaching of Chemistry.- Computer Enhanced Chemical Education: Any Computer Can Be Used.- The Effective Use of Non-Tutorial Computer Methods in Chemistry Education.- The Computer's Role in Undergraduate Chemistry Education: Report on a Study for UNESCO.- Automation in an Industrial Research Laboratory.- Current Research and Development in Computer-Aided Process Design.- Theoretical Studies of Metal Clusters as Models for Surface Phenomena.- Semi-Empirical Molecular Orbital Calculations Relevant to Adsorption and Catalysis On Metal Surfaces.- Comparison of Different Theoretical Approaches in the Study of Chemisorption On Metal Sources.- Cluster Method Multiple Scattering Calculations of Electronic Density of States for Amorphous and Liquid Metallic Alloys.- Description of Rapid Rearrangements With the Aid of Longuet-Higgins Group Theory. Spectroscopy and Reaction Mechanisms.- The Study of Chemical Structure and Reactivity By Means of Computations.- Computer Determination of Molecular Properties for Diatomics.- Computers as an Aid in Organic Synthesis Design.- Chemistry of Large Molecular Systems Using Molecular Quantum Mechanics.- Computer Planning of Research in Organic Chemistry.- Computer Aided Interpretation for the Structure Elucidation of Organic Compounds.- Computer Assisted Chemical Reasoning.- Dynamics of Chemisorption and Heterogeneous Reactions.- Quantum Chemistry and Small Molecule Dynamics.- List of Contributors.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 492 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This Brief reports on the interplay of an amino-acid mutation towards substrate which could lead to enhanced effects on mutant. These effects need to be given consideration in the engineering processes of protein stability and further exploration of such learning are required to provide novel indication for selection of an enzymes. There are very few reports showing such stable, energy efficient model towards improved protein function prediction screening in-silico structure based mutagenesis of xylanases from Thermomyces lanuginosus¿Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 52 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume contains the texts of the nineteen lectures presented at the NATO-ASI - FEBS Course on 'DNA - ligand interactions: from drugs to proteins.' The Advanced Study Institute (ASIl was held from August 30th to September 11th. 1986 in the Abbey of Fontevraud (France). The ASI was attended by 112 participants from a wide scientific horizon and from twentyone different countries. It was in some way a follow-up of the ASI held in Maratea. Italy in May 1981 and which was published in the NATO ASI Life Science series as volume 45. While much has been learned about the way the cellular machinery maintains and transmits the genetic heritage. as well as how these processes are regulated. little is Known about how the interactions between the various partners involved are taKing place. The interactions of drugs and proteins with nucleic acids are of evident importance in the understanding of these problems. The spectacular advances in recombinant DNA technology and the increased sophistication of biophysical techniques. in particular >:-ray diffraction and nuclear magnetic resonance. have created a scientific environment which is highly promising for the future of research in molecular biology. These advances permH the serious hope that biology on the molecular level may become a r-eality. Some of the contributions at the ASI presented the most recent advances in this e>:citing field.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 304 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Investment and risk management problems are fundamental problems for financial institutions and involve both speculative and hedging decisions. A structured approach to these problems naturally leads one to the field of applied mathematics in order to translate subjective probability beliefs and attitudes towards risk and reward into actual decisions.In Risk and Portfolio Analysis the authors present sound principles and useful methods for making investment and risk management decisions in the presence of hedgeable and non-hedgeable risks using the simplest possible principles, methods, and models that still capture the essential features of the real-world problems. They use rigorous, yet elementary mathematics, avoiding technically advanced approaches which have no clear methodological purpose and are practically irrelevant. The material progresses systematically and topics such as the pricing and hedging of derivative contracts, investment and hedging principles from portfolio theory, and risk measurement and multivariate models from risk management are covered appropriately. The theory is combined with numerous real-world examples that illustrate how the principles, methods, and models can be combined to approach concrete problems and to draw useful conclusions. Exercises are included at the end of the chapters to help reinforce the text and provide insight.This book will serve advanced undergraduate and graduate students, and practitioners in insurance, finance as well as regulators. Prerequisites include undergraduate level courses in linear algebra, analysis, statistics and probability. 352 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Apollo was known for its engineering triumphs, but its success also came from a disciplined management style. This excellent account of one of the most important personalities in early American human spaceflight history describes for the first time how George E. Mueller, the system manager of the human spaceflight program of the 1960s, applied the SPO methodology and other special considerations such as ¿all-up¿testing, resulting in the success of the Apollo Program. Wernher von Braun and others did not readily accept such testing or Mueller¿s approach to system management, but later acknowledged that without them NASA would not have landed astronauts on the Moon by 1969. While Apollo remained Mueller¿s priority, from his earliest days at the agency, he promoted a robust post-Apollo Program which resulted in Skylab, the Space Shuttle and the International Space Station. As a result of these efforts, Mueller earned the sobriquet: ¿the father of the space shuttle.¿ Following his success at NASA, Mueller returned to industry. Although he did not play a leading role in human spaceflight again, in 2011 the National Air and Space Museum awarded him their lifetime achievement trophy for his contributions.Following the contributions of George E. Mueller, in this unique book Arthur L. Slotkin answers such questions as: exactly how did the methods developed for use in the Air Force ballistic missile programs get modified and used in the Apollo Program How did George E. Mueller, with the help of others, manage the Apollo Program How did NASA centers, coming from federal agencies with cultures of their own, adapt to the new structured approach imposed from Washington George E. Mueller is the ideal central character for this book. He was instrumental in the creation of Apollo extension systems leading to Apollo, the Shuttle, and today¿s ISS and thus was a pivotal figure in early American human spaceflight history.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 336 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sexually transmitted infections (STI) continue to be a major cause of morbidity and mortality, both in developed industrial countries as well as in the developing world. Human immunodeficiency virus infections and the ensuing opportunistic infections are a major drain on the human and financial resources of many countries in the developing world and even with the availability of effective treatment the epidemic is not yet contained. Screening in developing worlds is difficult and there is a need for simple reliable cheap diagnostic methods that can be performed at the point of care, on the same day and by staff with limited training. Molecular biological methods are very attractive for the diagnosis of STI since a well defined range of pathogens is responsible for the infection. Diagnosis of Sexually Transmitted Diseases: Methods and Protocols strives to cover the full range of molecular testing for STI. Chapters cover a variety of topics such as aspects of DNA extraction from small volume samples or difficult tissues, simple, nested or multiplex PCR, use of duplex primers or other modifications of primers and PCR conditions, sequence analysis for genotyping, denaturing gel analysis, microarrays using liquid beads or microspheres and silicon nanoparticle-enhanced microcantilever detection of DNA. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Diagnosis of Sexually Transmitted Diseases: Methods and Protocols will be a valuable reference for the scientist looking to establish molecular methodologies for the diagnosis of STI tests in their own lab. 456 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers. 612 pp. Englisch.