Humana jul 2013 (80 risultati)

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing… better methods of diagnosis and treatment. In the pres ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by product of the host immune surveillance mechanism. Unstable mem brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer. 288 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The fifth Advanced Study Institute (ASI) on Techniques and Concepts of High Energy Physics was held again at the Hotel on the Cay, in the scenic harbor of Christiansted, St. Croix, U. S. Virgin Islands. The ASI brought together a t…otal of 71 participants, from 17 different countries. It was another great success, due to the dedication of the inspiring lecturers, the exceptional study body, and, of course, the beautiful setting. The primary support for the meeting was again provided by the Scientific Affairs Division of NATO. The ASI was cosponsored by the U.S. Department of Energy, by Fermilab, by the National Science Foundation, and by the University of Rochester. A special contribution from the Oliver S. and Jennie R. Donaldson Charitable Trust provided an important degree of flexibility, as well as support for worthy students from developing nations. As in the ca se of the previous ASI's, the scientific program was designed for advanced graduate students and recent PhD recipients in experimental particle physics. The present volume of lectures should complement the material published in the first four ASI's, and prove to be of value to a wider audience of physicists. 516 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present book contains three articles: 'Systems of Linear Differential Equations,' by V. P. Palamodov; 'Fredholm Operators and Their Generalizations,' by S. N. Krachkovskii and A. S. Di kanskii; and 'Representations of Groups an…d Algebras in Spaces with an Indefinite Metric' by M. A. Naimark and R. S. Ismagilov. In the fi.rst article the accent is on those characteristics of systems of differential equations which distinguish the systems from the scalar case. Considerable space is devoted in particular to 'nonquadratic systems,' a topic that has very recently stimulated interest. The second article is devoted to the algebraic aspects of the theory of operators (determinant theory in particular) in Banach and linear topological spaces. The third article reflects the present state of the art in the given area of the theory of representations, which has been re ceiving considerable attention in connection with its applications in physics (particularly in quantum field theory) and in the theory of differential equations. 120 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a result of a Workshop held at the Institute of Virology of the Univer sity of Würzburg, Germany in March of 1975. The Workshop was organized to bring together investigators of slow virus infections and other scientist…s, who have not engaged in such research, but who were Ieaders in the field of biologic investi gations. The conveners hoped that these latter would be more objective critics, who would express their views freely and who would offer recommendations for new directions and new approaches to the investigations of slow virus infections. These expectations were fulfilled as the organization of the Workshop permitted much free time for discussion as weil as time for directed critiques. This volume repre sents an extensive summary of the proceedings and the discussions that followed. We believe it will be of interest to all investigators of slow virus infections and to the students of host-parasite relationships. Volker ter Meulen Michael Katz V Contents Preface v List of Gontributars xi PART I I UNCONVENTIONAL AGENTS Chapter 1 Scrapie: Pathogenesis in lnbred Mice: An Assessment of Host Control and Response lnvolving Many Strains of Agent 3 A. G. Dickinsan and H. Fraser Chapter 2 Kuru, Creutzfeldt-Jakob Disease, and Transmissible Presenile Dementias 15 D. Garteton Gajdusek and Glarence J. Gibbs, Jr. Discussion I Chapters 1-2 50 Comment I Chapters 1-2 by G. A. Mims 52 Chapter 3 Sheep Progressive Pneumonia Viruses 54 Donald H. 276 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The first International Conference on Thermoelectric Properties of Metallic Conductors was held at Michigan State University on August 10-12, 1977. The conference was sponsored and supported by the National Science Foundation, the…Office of Naval Research and the Ford Motor Company. Although the topic may appear, at first glance, rather narrow and of limited interest, it impacts significantly on numerous fields of research, in each instance providing a unique and fru- ful technique for securing important data that is frequently difficult to obtain by other means. Thus, though thermoelectricity is the thread that binds these pages together, the papers constitute a patchwork quilt that includes critical phenomena, superconductivity, many-body theory, quasi one-dimensional systems, liquid metals, to mention only a few. This volume contains the 12 invited and 31 contributed papers, arranged in the order in which they were presented, as well as much of the frequently spirited and always illuminating discussion that followed these papers. Regrettably, not all of the discussion is included. Difficulties with the recording system during the first session (Wednesday morning) did not become apparent before the end of that session, and, consequently, none of the discussion--some of it fairly heated--appears in the proceedings; other remarks were lost to posterity through occasional malfunctioning of the record ing facilities and/or failure of speakers to come near a microphone. 436 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Conference on the Science and Technology of Thin Film Superconductors was conceived in the early part of 1988 as a forum for the specialist in thin film superconductivity. The conference was held on November 14-18, 1988, in Co…lorado Springs, Co lorado. Al though many excellent superconductivity conferences had been convened in the wake of the 1986-1987 discoveries in high temperature superconductivity, thin film topics were often dispersed among the sessions of a more general conference agenda. The response to the Conference on the Science and Technology of Thin Film Superconductors confirmed the need for an extended conference devoted to thin film superconductors. These proceedings are a major contribution to the technnology of thin film superconductivity because of the breadth and quality of the articles provided by leaders in the field. The proceedings are divided into articles on laser deposition, sputtering, evaporation, metal organic chemical vapor deposition, thick film, substrate studies, characterization, patterning and applications, and general properties. Most of the articles discuss scientific issues for high temperature thin film superconductors, although the conference was to be a forum for technology and scientific questions for both low and high temperature superconductivity. For the first day of the 5 day conference, Lawrence Berkeley Laboratory had organized an excellent set of short courses in superconduc t ing thin film devices. 576 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Follow-up studies of persons exposed to medical radiation have long shown that radiation induces cancer in man. This, coupled with increasing exposure from other sources including occupational and environmental radiations, has resu…lted in greater recognition of the importance of research on radiation-induced carcinogenesis and risk assessment with a view to radiation protection. One of the well-known late effects of radiation is the increased incidence of leukemia that occurred among atomic bomb survivors beginning two or three years after expo sure. A remarkable increase of solid tumors including cancers of the thyroid, breast and lung was also observed 10 to 20 years after exposure. Thus, many pathological, clinical and epidemiological studies have been made on radiation carcinogenesis in atomic bomb survivors by investigators at the Atomic Bomb Casualty Commission (ABCC), now known as the Radiation Effects Research Foundation (RERF), as well as by the staff of universities in Hiroshima and Nagasaki. Some of the mechanisms involved in radia tion carcinogenesis in man and associated modifying factors, such as age at time of ex posure and sex, have been elucidated by these studies. The results obtained are being used by such agencies as the International Commission on Radiation Protection (ICRP) for risk estimations of radiation exposure. This monograph presents the results realized thus far in these epidemiological and The incidence of radiation-induced cancer among atomic bomb pathological studies. 208 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Coding theory, system theory, and symbolic dynamics have much in common. Among the central themes in each of these subjects are the construction of state space representations, understanding of fundamental structural properties of…sequence spaces, construction of input/output systems, and understanding the special role played by algebraic structure. A major new theme in this area of research is that of codes and systems based on graphical models.This volume contains survey and research articles from leading researchers at the interface of these subjects. 540 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Motivation addresses a central problem in psychology: Why does an animal's behavior fluctuate in the face of an unaltered environment In a sense this is the opposite of the question from which work on motivation began, and for whic…h Claude Bernard invented the concept of the fixity of the internal milieu: How does an animal maintain constancy in the face of a fluctuating environment Dealing with motivation has become extremely complex as new experiments, phenomena, and theories have extended the concept. This book embodies some of the ways in which work on motivation is currently proceeding. One of the major changes has been the recognition that motivation cannot be explained without an understanding of the biological rhythms and activational systems that underlie behavior. Another is that ecological and evolutionary perspectives add enormously to answering the central problem of why an animal does what it does when it does. The book suffers from several omissions. There is no chapter on the devel opment of motivated behavior. There is none on reward systems in the brain, owing to the untimely death of James Olds, whose contribution would have enriched this book appreciably, and to whom we dedicate it. EVELYN SATINOFF PHILIP TEITELBAUM Vll Contents PART I UNDERLYING ACTIVATIONAL SYSTEMS CHAPTER 1 Motivation, Biological Clocks, and Temporal Organization of Behavior 3 Irving Zucker Reactivity to External Stimuli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Reactivity to Interoceptive Stimuli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Sources of Biological Rhythmicity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 Rhythm Generation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 . . . . . . . . . . Rhythm Synchronization. . . . . . . . . . . . . . . . . . . . . . . . . 10 . . . . . . . . . . Consequences of Rhythm Desynchronization . . . . . . . . . . . . . . 11 . . . . . 612 pp. Englisch.

Lingua: Inglese
Editore: Springer New York, Humana Jul 2013, 2013
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Policing and Punishing the Drinking Driver is at one level about the impact of specific drinking-driving countermeasures (punishments imposed by courts on convicted offenders and random breath testing) in a particular place (New So…uth Wales, Australia) in two particular years (1972 and 1983). At another level, however, the research reported herein is concerned with general questions of deterrence, and with the impact of the criminal justice system on the perception and behavior of a broad cross-section of the population. In contrast to much of the research in the drink-drive field, the research questions concentrate on the psychological and sociological processes whereby behavior is altered in the short-term as the result of a massive legal intervention or as the result of the routine imposition of legal punishments. 344 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The rapidly expanding fields of molecular and cellular neurobiology are the newest frontiers of neuroscience. This book represents the continuing efforts of the Institute of Developmental Neuroscience and Aging (IDNA) to disseminat…e the most recent advances on the developing and aging nervous system at the molecular and cellular levels. A group of neuroscientists presented and discussed their findings at a recent IDNA conference held in Athens, Greece, June 15-18, 1988. This meeting was sponsored by the National Hellenic Research Foundation, FIDIA, the Ministry of Research and Technology, the Tourism Organization of Greece, and the National Institute of Child Health and Human Development, NIH. The Directors of the IDNA are grateful to the local committee, Drs. Eleni Fleischer, Costas Sekeris, Michael Alexis, Theony Valcana, and Elias Kouvelas, for their efforts in organizing this meeting and for their successful integration of science and culture for the participants. This volume provides a comprehensive overview of the information presented at this conference, including in-depth discussions of each topic by the participants. The chapters are grouped into five general categories which correspond to the subject areas covered during the meeting. These include: Gene and Phenotypic Expression, Growth Factors and Oncogenes, Cytoskeletal and Extracellular Molecules, Neurotransmitters and Hormones, and Molecular Aspects of Aging and Alzheimer's Disease. The section on Gene and Phenotypic Expression includes discussions of transient gene expression in the nervous system (Herschman), developmental regulation of myelin-associated genes (Gordon et al. 340 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Collections of this sort are a regular publication feature of the Laboratory of Mathemati cal Geology of the Order of Lenin V. A. Steklov Mathematical Institute of the Academy of Sci ences of the USSR. In the future it is intended…that further collections and monographs reflect ing the activity of the Laboratory be issued. In this present collection, in addition to workers of the Laboratory of Mathematical Geology, specialists of both Russia and many foreign countries participated. This has permit ted us to display the general level of mathematization of geology in 1966. In order to enhance the overall view, the editors have included a section 'Chronicle and Bibliography' in which in formation is given on the most important actions relating to mathematization of geology taking place in 1965 and the first half of 1966, and which includes a bibliography on two-dimensional regressions having great practical value in geology but little known to us in the Soviet Union. 292 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Critical Points and Multicritical Points (Abstract).- Series Expansion Approximants for Singular Functions of Many Variables.- Structure and Thermodynamics of Interfaces.- A Van Der Waals Fixed Point.- Spin-Spin Correlation Functio…ns for the Two-Dimensional Ising Model.- Scaled Particle Theory of Hard Sphere Fluids to 1976.- Statistical Mechanics of Lattice Boson Field Theory.- On The Use of Determinants and their Expansions for Various Physical Problems.- Ring Diagram Contribution to Electron Correlations.- Fluctuations Near and Far from Equilibrium.- Stochastic Equations for Classical and Quantum Distribution Functions.- Stationary States and Noise in the Ballast Resistor, an Electro-Thermal Instability in a Conducting Wire.- Speculations on the Intrinsic Significance of Random Interactions.- A Dilation Problem in Non-Equilibrium Statistical Mechanics.- The Fractal Geometry of Percolation, Polymers and almost Everything Else.- On the Iterative Solution of a Stochastic Mapping.- Theory of the Surface Contribution to the Low Temperature Specific Heat of a Semi-Infinite Solid.- Optical Spectra Line Shape for Mixed Crystals.- Nonadiabatic Approach to Vibronically Assisted Radiationless Transitions.- The Generalized Master Equation and its Applications.- Two-Dimensional Anisotropic Random Walks.- Random Walks and Gamma Functions.- Steady-State Kinetics of a Linear Array of Interlocking Reactions.- Monte Carlo Models of Self Replicating Macromolecules I.- Combinatorial Aspects of Dynamics in Biological Systems.- The Transition of Two Stranded DNA to Single Strands.- Effective Behavior of Heterogeneous Media.- Unstable Brownian Motion of a Bus Trip.- Integration Errors in Image Reconstruction of Circularly Symmetric Objects in Computer Assisted Tomography.- The 'InternalReferencing' Structural Instability in an Environment Characterized by Random Variation: The Example of the N.Y.C. Banks in the Crisis of 1857.- The Theory of the Glory.- Exotic Matter in the Universe.- Some Statistical Observations from a 75 Year Run of Sears Roebuck Catalogues. 828 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1 Introduction: Disease, Disability, and Psychodiagnostic Concepts in Childhood.- 2 Childhood Psychosis: A Historical Review.- 3 Specific Language Dysfunctioning in Children: A Historical Overview.- 4 Deviant and Normal Social Deve…lopment.- 5 Normal Social Development.- 6 Psycholinguistic Development: Functioning and Dysfunctioning.- 7 Disordered Thinking.- 8 Diagnosis and Evaluation of Disordered Thought and Language.- 9 The Psychological Testing of Dysphasic and Psychotic Children.- Epilogue.- References and Bibliography. 216 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -At the close of the year 1900, motor vehicle registrations throughout the United States totaled 8000. These vehicles rode on unpaved and often dusty country roads. The only problem of traffic was an occasional pedestrian or a frigh…tened horse or cow frenzied by the roar of this new creature. Today more than 82,000,000 registrations, representing 50% of the world's automobiles, are recorded in this country. In 1963 these vehicles traveled 798 billion miles over newly constructed modern highways, expressways, freeways, quickways, and thru ways, as well as improved rural and urban roads and streets. Out of all this has sprung the traffic engineer. Today's modern roadway is an engineering structure which has been developed through sound principles of design with provisions for safety and efficiency. An example of this safety factor can be found by the exacting specifications for cross sections, grades, roadside control, medians, and other design features. For many years, the responsi bility for controlling traffic fell naturally into the domain of the police. However, as traffic increased, many problems developed which were beyond the scope of normal police work. Since the highway system is an engineering structure which requires an engi neering approach to appraise operating problems and engineering techniques to solve them, the traffic engineer came into being. 236 pp. Englisch.

Lingua: Inglese
Editore: Springer, Humana Jul 2013, 2013
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aimed at mathematicians and computer scientists who will only be exposed to one course in this area, Computability: A Mathematical Sketchbook provides a brief but rigorous introduction to the abstract theory of computation, sometim…es also referred to as recursion theory. It develops major themes in computability theory, such as Rice's theorem and the recursion theorem, and provides a systematic account of Blum's complexity theory as well as an introduction to the theory of computable real numbers and functions. The book is intended as a university text, but it may also be used for self-study; appropriate exercises and solutions are included. 196 pp. Englisch.

Lingua: Inglese
Editore: Birkhäuser, Humana Jul 2013, 2013
Serie: Libro 11 di 23 - Birkhäuser Advanced Texts Basler Lehrbücher
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intended as a self-contained introduction to measure theory, this textbook also includes a comprehensive treatment of integration on locally compact Hausdorff spaces, the analytic and Borel subsets of Polish spaces, and Haar measures on l…ocally compact groups. This second edition includes a chapter on measure-theoretic probability theory, plus brief treatments of the Banach-Tarski paradox, the Henstock-Kurzweil integral, the Daniell integral, and the existence of liftings. Measure Theory provides a solid background for study in both functional analysis and probability theory and is an excellent resource for advanced undergraduate and graduate students in mathematics. The prerequisites for this book are basic courses in point-set topology and in analysis, and the appendices present a thorough review of essential background material. 480 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Operative Gynecologic Endoscopy, Second Edition is completely revised and expanded with 17 new chapters that provide, step-by-step, the latest operative techniques for both laparoscopic AND hysteroscopic procedures. New and updated cha…pters include: laparoscopic assisted vaginal hysterectomy; vaginal prolapse and bladder suspension; ectopic pregnancy; tubal reconstructive surgery; assisted reproductive technologies; lymphadenectomy and urologic procedures; operative hysteroscopy. In addition, this volume includes comprehensive chapters on instrumentation, photo documentation, anesthesia, operating room personnel, credentialing, and legal issues. More than 350 superb illustrations - with many in full color - complement and clarify the operative techniques. For every surgeon and resident performing gynecologic procedures, this is the definitive, most up-to-date text on gynecologic endoscopy.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 568 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The recent generation in the laboratory of phase squeezed and intensity squeezed light beams has brought to fruition the theoretical predictions of such non-classical phenomena which have been made and developed in recent years by a nu…mber of workers in the field of quantum optics. A vigorous development is now underway of both theory and experiment and the first measurements have been coi:Jfirmed and extended already in some half dozen laboratories. Although the fields of application of these novellight sources are as yet somewhat hazy in our minds and some inspired thinking is required along these lines, the pace and excitement of the research is very clear. It is to he hoped that the new possibilities of: making measurements below the quantum shot noise lirnit which is made possible by these squeezed states of light willlead to further fundamental advances in the near future. In this NATO ARW a number of the leaders in the field met in the extremely pleasant surroundings of Cortina d'Ampezzo and their contributions are recorded in this volume. The meeting was held at the Istituto d'Arte which was enjoying its lOOth anniversary celebrations. This ARW was preceeded by an ONR Special Seminar on 'Photons and Quantum Fluctuations', the proceedings of which will be published by Adam Hilger Ltd. The timeliness of the meeting was acknowledged by the support of the NATO Scientific Affairs Division which we would like to acknowledge on behalf of all the participants.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 348 pp. Englisch.

Lingua: Inglese
Editore: Springer, Humana Jul 2013, 2013
Serie: Libro 20 di 42 - The Springer Series on Demographic Methods and Population Analysis
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Oscar Harkavy offers a unique insider's view of the fascinating world of population politics. Chapters trace the growth of the movement as well as the various foundations, governments, and intergovernmental organizations which were an…integral part of it from its beginning in the 1950s, through its growth during the 60s and 70s, to the present. Topics include the role of social science in understanding the causes and effects of population growth; reproductive research and contraceptive development; and the politics of family planning, sex education, and abortion in the United States.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 296 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -During the past 20 years there have been amazing developments in low temperature physics, engineering, and biology. They form part of the very rapid post-war growth in pure and applied sciences of every kind. During this period several… branches of biology including immunology, molecular biology and, of course, cryobiology, have split off from their parent disciplines. One result of this splintering has been the development of separate jargons used by the specialists and sometimes incomprehensible to those working in closely allied fields. The pure physicists, chemists, and the applied scientists, including physicians, surgeons, and pathologists, find the new jargons particularly baffling. We have attempted in this monograph to present to cryogenic engineers a picture of cryobiologists and their problems using as few strange technical words as possible. We hope that this book will help to bridge the gap which has already formed between them in spite of the opportunities for collaboration in many projects. We hope that it may also be useful to scientific research workers and postgraduate students of many kinds united only by curiosity about cryobiology. We are very much indebted to Dr. K. Mendelssohn, who insti gated us to produce a monograph and who reassured us that cryogenic engineers are as keen to understand the current trends in biology, and particularly in cryobiology, as we are to enlist their help. We have had much help in preparing this book.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 268 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -of Volume 8.- 71 Allergic reactions in acute bacterial and viral infectious diseases and active immunization procedures.- 72 Allergy and immunity in tuberculosis.- 73 Immunoallergologic aspects of syphilis.- 74 Allergy and immunity in…leprosy.- 75 Mycotic allergy.- 76 Immunoallergologic aspects of gonorrhoea.- 77 Immunoallergologic aspects of chancroid.- 78 Immunoallergologic aspects of lymphogranuloma venereum.- 79 Immunoallergic manifestations of human protozoan and helminth diseases.- 80 Insects, mites and other venomous arthropods causing allergic or immunologic reactions in man.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 376 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing bet…ter methods of diagnosis and treatment. In the pres ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by product of the host immune surveillance mechanism. Unstable mem brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 288 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Ninth Biennial Polymer Symposium, sponsored by the Division of Polymer Chemistry of the American Chemical Society, was convened during November 18-22, 1978 at Key Biscayne, Florida. The symposium also marks the occasion when the Se…cond Division of Polymer Chemistry Award was presented to Professor C. S. Marvel for his outstanding achievements in polymer chemistry. The proceedings of this Symposium are recorded in this volume. Carl Shipp Marvel, more popularly known as Speed Marvel, was born in Waynesville, Illinois in 1894. He received his A.B. and M.S. degrees at Illinois Wesleyan University, and M.A. and Ph.D. degrees at the University of Illinois. After having completed his graduate education, Professor Harvel remained at the University as a member of the Chem istry faculty. He 'retired' from Illinois in 1961, and moved to the University of Arizona where he continued his research in polymer chemistry. Out of the more than 500 publications, over 100 were from Arizona during his active retirement. Speed has so far trained 176 Ph.D. students and 128 postdoctoral fellows, and inspired countless young chemists to the science of macromolecules. No doubt these numbers will increase along with his scientific productivity. Professor Harvel has been honored on numerous ocasions prior to receiving the Division of Polymer Chemistry Award.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 356 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Justbefore the preliminary programof Orbis Scientiae 1998 went to press the news in physics was suddenly dominated by the discovery that neutrinos are, after all, massive particles. This was predicted by some physicists including Dr. B…ehram Kusunoglu, who had apaper published on this subject in 1976 in the Physical Review. Massive neutrinos do not necessarily simplify the physics of elementary particles but they do give elementary particle physics a new direction. If the dark matter content ofthe universe turns out to consist ofneutrinos, the fact that they are massive should make an impact on cosmology. Some of the papers in this volume have attempted to provide answers to these questions. We have a long way to go before we find the real reasons for nature¿s creation of neutrinos. Another neutrino-related event was the passing of their discoverer, Fredrick Reines: The trustees of the Global Foundation, members of the Orbis Scientiae 1998, dedicate this conference to Fredrick Reines of the University of California at Irvine. The late Professor Reines was a loyal and active member of these series of conferences on the frontiers of physics and cosmology since 1964. He also sewed as one of the trustees of the Global Foundation for the past three years. Professor Reines discovered the most elusive particle, the neutrino, in 1954. We are proud to say that we recognized the importance of this discovery by awarding him the J.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 264 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -1 Introduction: Disease, Disability, and Psychodiagnostic Concepts in Childhood.- 2 Childhood Psychosis: A Historical Review.- 3 Specific Language Dysfunctioning in Children: A Historical Overview.- 4 Deviant and Normal Social Developm…ent.- 5 Normal Social Development.- 6 Psycholinguistic Development: Functioning and Dysfunctioning.- 7 Disordered Thinking.- 8 Diagnosis and Evaluation of Disordered Thought and Language.- 9 The Psychological Testing of Dysphasic and Psychotic Children.- Epilogue.- References and Bibliography.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 216 pp. Englisch.

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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The innate immune system represents a critical arm of the immune response by providing immediate and robust host defense; however, human studies of its function are often limited by ethical, logistical, and technical obstacles. In Mouse M…odels of Innate Immunity: Methods and Protocols, experts in the field explore the design and execution of experiments used to thoroughly evaluate critical elements associated with the host innate immune response. The volume opens with methods that are essential for collecting and assessing various primary cells that are highly relevant to innate immunity, and it continues with in vivo protocols commonly used to evaluate the innate immune response in the mouse, including mouse models of respiratory infection, gastrointestinal inflammation, fungal and parasitic diseases, sepsis, and HIV-1 infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Mouse Models of Innate Immunity: Methods and Protocols will serve the research community by providing expert advice and protocols that allow both experienced and novice investigators to successfully plan, implement, and assess disease processes associated with the innate immune response. 240 pp. Englisch.

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cellular adhesion is a fundamental process that influences numerous biological activities such as morphogenesis, cell motility and division, as well as signalling. In addition, adhesion is a process important not only in normal physiology… and development, but also in disease states such as tumourigenesis, cardiovascular disease, inflammation and infection. There are a plethora of proteins involved in adhesion-related events with a huge diversity in function. As a result, a wide variety of techniques exist to study adhesion related proteins and processes. In Adhesion Protein Protocols, Third Edition, chapters cover techniques to gain insight into the complex and incompletely understood processes that are involved in cellular adhesion. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Adhesion Protein Protocols, Third Edition will be useful for both those new to the field of adhesion protein research as well as the more experienced scientist. 420 pp. Englisch.

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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one 'how to' manual for basic scientists interested in initiating a drug discovery effort. Wh…ile this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making 'go/no-go' decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Step-by-step and practical, Phosphatase Modulators offers a path to understanding many of the facets and complexities associated with undertaking a drug discovery effort and will serve as a roadmap to initiating those efforts. 328 pp. Englisch.

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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although antiviral drugs have been successfully developed for some viral diseases, there remains a clear, unmet medical need to develop novel antiviral agents for the control and management of many viruses that currently have no or limite…d treatment options as well as a need to overcome the limitations associated with the existing antiviral drugs, such as adverse effects and emergence of drug-resistant mutations. The second edition of Antiviral Methods and Protocols features: All chapters are new and written by experts in the field, reflecting the major recent technical advances in antiviral research and discovery. This edition focuses on many important human viruses, such as human immunodeficiency virus type 1 (HIV-1), hepatitis viruses (hepatitis B and C viruses), herpes viruses, human respiratory syncytial virus (RSV), and influenza virus, while also featuring some important emerging viruses, such as dengue virus, West Nile virus, and chikungunya virus. As a volume in the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Antiviral Methods and Protocols, Second Edition will serve as an excellent laboratory reference for pharmaceutical and academic biologists, medicinal chemists, and pharmacologists as well as for virologists in the field of antiviral research and drug discovery. 468 pp. Englisch.