Humana mai 2008 (23 risultati)

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While much information has been gained regarding the molecular nature of prion proteins, only recently have several research groups begun to cast light on turning the normal prion protein into its aberrant, infectious form. In this book, a team of experts provide the most up-to-date collection of current methods in this unique area of neuroscience. Comprehensive and cutting-edge, this is an ideal collection for researchers investigating the growing field of mammalian prion disease. 296 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The field of toxicogenomics has been growing quickly,yet with rapid growth comes the need to periodically reflect on the nature of the field. Essential Conceptsin Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals. Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use ofsuch data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology(TM) series format, this volumeretains the practicality and usefulness of the highly successful series.Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who mustkeep up-to-date onprogress inthis vital and importantfield. 300 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this thorough and state-of-the-art book, top experts provide cutting edge techniques which greatly expand the depth and scope of classical invasive prenatal diagnosis. The book features a totally unique focus on novel non-invasive approaches for prenatal diagnosis. Following the Methods in Molecular Biology(TM) series format, the chapters feature step-by-step laboratory protocols, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. 348 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity.- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology.- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications.- Role of Statistics in Toxicogenomics.- Predictive Toxicogenomics in Preclinical Discovery.- In Vivo Predictive Toxicogenomics.- Bioinformatics: Databasing and Gene Annotation.- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics.- Toxicogenomics in Biomarker Discovery.- From Pharmacogenomics to Translational Biomarkers.- Public Consortium Efforts in Toxicogenomics.- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Prion Protein Protocols brings together a collection of current protocols in the field of mammalian prion disease research. Since identification of the prion protein gene some 20 years ago, what were once thought to be rare, neurodegenerative diseases of humans and animals have become a major research area. The major interest in this field results from the epidemic of bovine spongiform encephalopathy and the subsequent human prion disease, variant Creutzfeldt¿Jakob disease, which still poses an unknown risk to human health. The ¿unknowns¿ in the field stem from the enigmatic nature of infectious prions, the infectious agent that can transmit these diseases between individuals. Although much information has been gained over the past two decades about the molecular nature of prion proteins, only very recently have several research groups begun to cast light on how to turn the normal prion protein into its aberrant, infectious form. Prion Protein Protocols brings together a collection of protocols from 13 diff- ent laboratories in five countries covering basic science and diagnostic areas of prion research. Together, the chapters provide an up-to-date collection of current methods in this unique area of neuroscience. The notes section at the end of each methods chapter provides useful insight into the experimental techniques, and they are no doubt a benefit to researchers wanting to use these technologies.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -With molecular biology now allowing greater accuracy in prenatal diagnosis given amounts of fetal material as small as single cells, a major current focus has grown in the development of rapid, cost-effective diagnoses. This book has a totally unique focus on novel non-invasive approaches for prenatal diagnosis. Top experts provide cutting edge applications for the rapid assessment of fetal aneuploidies and Mendelian disorders on fetal material gained by invasive approaches, as well as procedures being validated for routine, non-invasive clinical analysis of cell free fetal DNA. Following the Methods in Molecular Biology(TM) series format, the chapters feature step-by-step laboratory protocols, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. Thorough and state-of-the-art, this is an ideal volume for researchers and molecular biologists invested in ever-growing field of prenatal medicine.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Bioinformatics, leading researchers provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and 'meta-methods' for developers of bioinformatics algorithms. Over 80 authors from around the globe have contributed to the two volumes. 520 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Over 80 authors from around the globe contribute to the two volumes, including many leading experts in their respective subjects. They encompass topics from across the diverse field of bioinformatics through its broad scope, combining to provide an inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists. 576 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed. 336 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and 'meta-methods' for developers of bioinformatics algorithms. Over 80 authors from around the globe have contributed to the two volumes, including many leading experts, representing an inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 520 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In this book, leading researchers in the field of Bioinformatics provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Over 80 authors from around the globe contribute to the two volumes, including many leading experts in their respective subjects. They encompass topics from across the diverse field of bioinformatics through its broad scope, combining to provide an inter-disciplinary collaboration involving biologists, biochemists, physicists, mathematicians, statisticians and computer scientists.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 576 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the third edition of this book. In this updated and expanded edition, the reader is provided with the most contemporary information and literature supported by a close survey of the field. Several new chapters dealing with new concepts in biology and treatment of mental disorders have been added. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry. 799 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this practical book, the authors of each chapter have synthesized the currently available evidence regarding specific issues in diabetes care. The chapters have been written by an interdisciplinary team of scientists and medical professionals. Such an approach emphasizes the need for collaboration in the care of any individual with diabetes and in the effort to find new therapies for the disease. This reference provides practical guidance in a single resource. 492 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, this book provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors. This book is the first of its kind, encyclopedic and wide-ranging. 464 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a collection of methods of practical design, calculation and numerical examples that illustrate how organized, analytical reasoning can lead to the discovery of clear, direct solutions to pollution especially in the areas of biosolids management, treatment, disposal and beneficial use. The book contains an extensive collection of detailed design examples and case histories, and a distinguished panel of authors provides insight into a range of topics. 824 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. The new therapies have led to significant improvements in patient function, quality of life and survival. In this book, expert authors describe these new therapies. It will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists. 464 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, The Genetics and Molecular Biology of Neural Tumors provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. Each chapter, with a comprehensive list of references and many informative tables, contains clinical and epidemiologic information, as well as succinct but relevant patho-histologic and immunohistochemical descriptions facilitating the interpretation of the findings on tumor genetics and molecular biology. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors.As a ready and concentrated source, The Genetics and Molecular Biology of Neural Tumors is the perfect reference for busy clinicians, clinical investigators and laboratory researchers struggling through the copious and far-spread research on this subject.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 464 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Over the last 30 years, pollution and its effects on the environment have emerged as leading topics of interest. The desire for positive action to restore and protect the environment is growing worldwide. How serious are particular types of pollution Is technology currently available to abate pollution And do the costs of abatement justify the degree of abatement achieved In the series, Handbook of Environmental Engineering, these questions are answered for the three basic forms of pollution and waste: gas, solid and liquid. Volume 7 in the series, Biosolids Engineering and Management, is a collection of methods of practical design, calculation and numerical examples that illustrate how organized, analytical reasoning can lead to the discovery of clear, direct solutions, especially in the areas of biosolids management, treatment, disposal and beneficial use. The book¿s distinguished panel of authors provides insight into a range of topics, including sludge and biosolids transport, pumping and storage, sludge conversion to biosolids, chlorination, stabilization, regulatory requirements, costs, agricultural land application, landfill, ocean disposal, combustion, incineration and sludge treatment process selection. Along with its sister book - Volume 6, Biosolids Treatment Processes ¿ Volume 7 is designed to be a basic biosolids treatment textbook, as well as a comprehensive reference book for advanced undergraduate and graduate students, designers of waste treatment systems, scientists and researchers. Both insightful and illuminating, Volume 7, Biosolids Engineering and Management gives state-of-the-art illustrations of the theory and practice of individual biosolids management systems and pertinent information on physical, chemical and biological treatment technologies used today.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 824 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This timely volume addresses the areas of pathophysiology and therapy of pulmonary hypertension, which have seen exciting developments over the past decade. The discoveries of endothelin overexpression as well as prostacyclin and nitric oxide deficiency in association with pulmonary hypertension have led to important therapeutic insights. In addition, the identification of genes associated with pulmonary hypertension has just begun to open the door to new pathophysiologic insights. The new therapies have led to significant improvements in patient function, quality of life and survival. In this book, expert authors describe these new therapies. It will be of interest not only to cardiologists, pulmonary specialists and rheumatologists, but also many nurses and pharmacotherapists are becoming increasingly involved in the therapy of patients with pulmonary hypertension.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 464 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In this practical book, the authors of each chapter have synthesized the currently available evidence regarding specific issues in diabetes care. The book begins with background information on the epidemiology and pathology of disease. Following chapters address specific issues in the diagnosis and treatment of type 2 diabetes. Chapters integrating the best evidence for the evaluation and treatment of comorbidities of diabetes, including hypetension, hyperlipidemia, and vascular disease collect a wealth of information in a single resource. Finally, the book highlights related conditions, including fatty liver disease, pregnancy and polycystic ovarian syndrome. The chapters have been written by an interdisciplinary team of scientists and medical professionals. Such an approach emphasizes the need for collaboration in the care of any individual with diabetes and in the effort to find new therapies for the disease.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 492 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Biotechnology for Fuels and Chemicals: The Twenty-Ninth Symposium, leading US and international researchers from academia, industry, and government exchange cutting-edge technical information and update current trends in the development and application of biotechnology for sustainable production of fuels and chemicals. This symposium emphasizes advances in biotechnology to produce high-volume, low-price products from renewable resources, while improving the environment. The major areas of interest include advanced feedstock production and processing, enzymatic and microbial biocatalysis, bioprocess research and development, opportunities in biorefineries, and commercialization of biobased products. International and domestic progress on producing liquid biofuels, especially ethanol and biodiesel, is highlighted, and related topics, including bioseparations and optimal integration of biochemical and thermochemical conversion technologies, are featured. Forward-looking and authoritative, Biotechnology for Fuels and Chemicals: The Twenty-NInth Symposium provides an illuminating overview of current research and development in the production of commodity fuels and chemicals from renewable biomass resources via biochemical and thermochemical routes. 816 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Session 1A.- Session 1B.- Session 2.- Session 3.- Session 4.- Session 5A.- Session 5B.- Session 6.- Special Topic B.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 816 pp. Englisch.