Humana mai 2010 (11 risultati)

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970's. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study. 308 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plants have evolved an amazing array of metabolic pathways leading to molecules capable of responding promptly and effectively to stress situations imposed by biotic and abiotic factors, some of which supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, food and chemical additives, biofuels, and biomass. In Plant Secondary Metabolism Engineering: Methods and Applications, expert researchers provide detailed practical information on some of the most important methods employed in the engineering of plant secondary metabolism pathways and in the acquisition of essential knowledge in performing this activity, including the significant advances and emerging strategies. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Plant Secondary Metabolism Engineering: Methods and Applications will aid scientists engaged in the challenging task of modifying some of the most intricate products of plant evolution and support their efforts directed toward the vital goal of sustainable natural chemicals. 352 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970¿s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology¿ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Plants have evolved an amazing array of metabolic pathways leading to molecules capable of responding promptly and effectively to stress situations imposed by biotic and abiotic factors, some of which supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, food and chemical additives, biofuels, and biomass. In Plant Secondary Metabolism Engineering: Methods and Applications, expert researchers provide detailed practical information on some of the most important methods employed in the engineering of plant secondary metabolism pathways and in the acquisition of essential knowledge in performing this activity, including the significant advances and emerging strategies. Written in the highly successful Methods in Molecular Biology¿ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Plant Secondary Metabolism Engineering: Methods and Applications will aid scientists engaged in the challenging task of modifying some of the most intricate products of plant evolution and support their efforts directed toward the vital goal of sustainable natural chemicals.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 352 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been 5 years since publication of the first edition of Dr. Attarian's Clinical Handbook of Insomnia which at the time was the first significant cl- ical textbook dedicated to insomnia, an often overlooked but important me- cal problem. The book was very well received. There has now been sufficient new information on the subject to warrant a second expanded edition of this very useful volume. Then, as now, the approach is to emphasize the frequent biological causes of insomnia rather than to attribute it primarily to underlying psychological and emotional factors. This new edition is an impressive major effort, having been expanded from 14 to 23 chapters including an extensive revision and updating of previous chapters with new references and the ad- tion of many new authors. An entirely new section of the book deals with insomnia in special populations including teenagers, pregnancy, menopause, and the geriatric population. Other new topics include insomnia as enco- tered in primary care practice, the role of circadian rhythms, the contribution of sleep related movement disorders to insomnia, insomnia in pain disorders, and the interesting entity of paradoxical insomnia, in which there is a large d- crepancy between the objective and subjective estimation of quantity of sleep. This collection within a single volume of practical information concerning a common but often neglected disorder remains a very useful addition to the armamentarium of the general or specialty physician who wishes to properly address insomnia in an informed and responsible manner. 364 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment provides proven approaches and suggestions for finding sources of microbiological contamination of industrially produced products.Industrial food safety professionals find themselves responsible for locating and eliminating the source(s) of food contamination. These are often complex situations for which they have not been adequately prepared. This book is written with them, the in-plant food safety/quality assurance professional, in mind. However, other professionals will also benefit including plant managers, regulatory field investigators, technical food safety policy makers, college instructors, and students of food science and microbiology.A survey of the personal and societal costs of microbial contamination of food is followed by a wide range of respected authors who describe selected bacterial pathogens, emerging pathogens, spoilage organisms and their significance to the industry and consumer. Dr. Kornacki then provides real life examples of in-plant risk areas / practices (depicted with photographs taken from a wide variety of food processing facilities). Factors influencing microbial growth, survival and death area also described. The reader will find herein a practical framework for troubleshooting and for assessing the potential for product contamination in their own facilities, as well as suggestions for conducting their own in-plant investigations. Selected tools for testing the environment and statistical approaches to testing ingredients and finished product are also described. The book provides suggestions for starting up after a processing line (or lines) have been shut down due to a contamination risk. The authors conclude with an overview of molecular subtyping and its value with regard to in-plant investigations.Numerous nationally recognized authors in the field have contributed to the book. The editor, Dr. Jeffery L. Kornacki, is President and Senior Technical Director of the consulting firm, Kornacki Microbiology Solutions in Madison, Wisconsin. He is also Adjunct Faculty with the Department of Food Science at the University of Georgia and also with the National Food Safety & Toxicology Center at Michigan State University. 208 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It has been 5 years since publication of the first edition of Dr. Attarian¿s Clinical Handbook of Insomnia which at the time was the first significant cl- ical textbook dedicated to insomnia, an often overlooked but important me- cal problem. The book was very well received. There has now been sufficient new information on the subject to warrant a second expanded edition of this very useful volume. Then, as now, the approach is to emphasize the frequent biological causes of insomnia rather than to attribute it primarily to underlying psychological and emotional factors. This new edition is an impressive major effort, having been expanded from 14 to 23 chapters including an extensive revision and updating of previous chapters with new references and the ad- tion of many new authors. An entirely new section of the book deals with insomnia in special populations including teenagers, pregnancy, menopause, and the geriatric population. Other new topics include insomnia as enco- tered in primary care practice, the role of circadian rhythms, the contribution of sleep related movement disorders to insomnia, insomnia in pain disorders, and the interesting entity of paradoxical insomnia, in which there is a large d- crepancy between the objective and subjective estimation of quantity of sleep. This collection within a single volume of practical information concerning a common but often neglected disorder remains a very useful addition to the armamentarium of the general or specialty physician who wishes to properly address insomnia in an informed and responsible manner.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This state-of-the-art book presents the forefront in the science and clinical management of myeloma bone disease. Assembling the work of the world'spremier thought leaders, this book begins with sections on clinical presentation, imaging, and biochemical markers and then goes on to discuss radiation, surgical, and medical therapies. Specific chapters are devoted to bisphosphonates and novel therapeutic agents, such as RANKL inhibitors, Wnt signaling inhibitors, and IMiDs. The mechanisms of osteoclast activation and osteoblast suppression in multiple myeloma are also explored.Myeloma Bone Disease is a valuable resource for medical, surgical, and radiation oncologists and cancer researchers. 264 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Principles of Microbiological Troubleshooting in the Industrial Food Processing Environment provides proven approaches and suggestions for finding sources of microbiological contamination of industrially produced products.Industrial food safety professionals find themselves responsible for locating and eliminating the source(s) of food contamination. These are often complex situations for which they have not been adequately prepared. This book is written with them, the in-plant food safety/quality assurance professional, in mind. However, other professionals will also benefit including plant managers, regulatory field investigators, technical food safety policy makers, college instructors, and students of food science and microbiology.A survey of the personal and societal costs of microbial contamination of food is followed by a wide range of respected authors who describe selected bacterial pathogens, emerging pathogens, spoilage organisms and their significance to the industry and consumer. Dr. Kornacki then provides real life examples of in-plant risk areas / practices (depicted with photographs taken from a wide variety of food processing facilities). Factors influencing microbial growth, survival and death area also described. The reader will find herein a practical framework for troubleshooting and for assessing the potential for product contamination in their own facilities, as well as suggestions for conducting their own in-plant investigations. Selected tools for testing the environment and statistical approaches to testing ingredients and finished product are also described. The book provides suggestions for starting up after a processing line (or lines) have been shut down due to a contamination risk. The authors conclude with an overview of molecular subtyping and its value with regard to in-plant investigations.Numerous nationally recognized authors in the field have contributed to the book. The editor, Dr. Jeffery L. Kornacki, is President and Senior Technical Director of the consulting firm, Kornacki Microbiology Solutions in Madison, Wisconsin. He is also Adjunct Faculty with the Department of Food Science at the University of Georgia and also with the National Food Safety & Toxicology Center at Michigan State University.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 208 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Clinical Presentation of Myeloma Bone Disease.- Imaging of Multiple Myeloma, Solitary Plasmacytoma, MGUS, and Other Plasma Cell Dyscrasias.- Biochemical Markers of Bone Remodeling in Multiple Myeloma.- Radiation Therapy in Multiple Myeloma.- Surgical Management of Bone Disease.- Bisphosphonates in the Treatment of Myeloma Bone Disease.- Osteonecrosis of the Jaw.- Murine Models of Myeloma Bone Disease: The Importance of Choice.- RANK Ligand Is a Therapeutic Target in Multiple Myeloma.- Osteoclast Activation in Multiple Myeloma.- Potential Role of IMiDs and Other Agents as Therapy for Myeloma Bone Disease.- Proteasome Inhibitors and the Wnt Signaling Pathway in Myeloma Bone Disease.- Mechanisms Involved in Osteoblast Suppression in Multiple Myeloma.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Ultra-wideband (UWB), short-pulse (SP) electromagnetics are now being used for an increasingly wide variety of applications, including collision avoidance radar, concealed object detection, and communications. Notable progress in UWB and SP technologies has been achieved by investigations of their theoretical bases and improvements in solid-state manufacturing, computers, and digitizers. UWB radar systems are also being used for mine clearing, oil pipeline inspections, archeology, geology, and electronic effects testing. Ultra-wideband Short-Pulse Electromagnetics 9 presents selected papers of deep technical content and high scientific quality from the UWB-SP9 Conference, which was held from July 21-25, 2008, in Lausanne, Switzerland. The wide-ranging coverage includes contributions on electromagnetic theory, time-domain computational techniques, modeling techniques, antennas, pulsed-power, UWB interactions, radar systems, UWB communications, broadband systems and components. This book serves as a state-of-the-art reference for scientists and engineers working in these applications areas.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 524 pp. Englisch. …