Humana okt 2016 (156 risultati)

Lingua: Inglese
Editore: Springer, Humana Okt 2016, 2016
Serie: Undergraduate Texts in Mathematics, Libro 143 di 170. Libro 143 di 170 - Undergraduate Texts in Mathematics
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 58,84
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text gives a rigorous treatment of the foundations of calculus. In contrast to more traditional approaches, infinite sequences and series are placed at the forefront. The approach taken has not only the merit of simplicity, bu…t students are well placed to understand and appreciate more sophisticated concepts in advanced mathematics. The authors mitigate potential difficulties in mastering the material by motivating definitions, results and proofs. Simple examples are provided to illustrate new material and exercises are included at the end of most sections. Noteworthy topics include: an extensive discussion of convergence tests for infinite series, Wallis's formula and Stirling's formula, proofs of the irrationality of pi and e and a treatment of Newton's method as a special instance of finding fixed points of iterated functions. 488 pp. Englisch.

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 58,84
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This innovative volume details counseling interventions for secondary students with ADHD and its associated academic and conduct problems, particularly focusing on youth at risk for developing serious disruptive behaviors. It addre…sses the continuing debate over counseling for youths with ADHD by identifying key elements common to reputable therapies and suggesting a framework for their successful implementation. The core of the book discusses the Challenging Horizons Program (CHP), a behavior- and solutions-focused approach to counseling adolescents with ADHD that has been studied extensively for more than 15 years. Based on the quality of research, the CHP has been included in the National Registry of Evidence-based Programs and Practices maintained by the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA). Excerpts from actual sessions illustrate typical therapist-client interactions in the CHP, and sample modules from the program's treatment literature expand the book's descriptions of effective hands-on interventions. Counseling skills featured in this book include:Bridging the research-into-practice divide.Establishing a therapeutic alliance with students with ADHD.Developing and implementing interventions for memory, organization, and planning.Enhancing young clients' social skills.Enlisting family members in the intervention process.Working directly with teachers to improve student behaviors.A Practical Guide to Implementing School-Based Interventions for Adolescents with ADHD is an essential resource for researchers, clinicians and related professionals, and graduate students in such disciplines as school and clinical child psychology, social work, educational psychology, psychotherapy and counseling, and learning and instruction. 228 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 53,49
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The second edition of this volume provides novel protocols for the study of newly discovered function and modifications of components of the Hh pathways. The first few chapters discuss methods for stable delivery of soluble Hh proteins… in cell cultures that can be adapted for in vivo studies, and mathematical models for studying Hh proteins gradient formation in tissues. The next few chapters explore studies in cell culture using fibroblasts that respond readily to Hh proteins. The book goes on to present protocols for evaluation of transcriptional activity of the Gli transcription factors in cell cultures and determine the expression level of endogenous Gli proteins. The final chapters talk about metabolic effects of noncanonical Hh signaling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, Hedgehog Signaling Protocols, Second Edition presents researchers with a comprehensive understanding of the Hh pathway and its function in development and diseases.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 216 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume is the most up-to-date text available on diffuse malignant mesothelioma and includes all the newest imaging modalities, immunohistochemical features, and ever-expanding information on the molecular characteristics of the ca…ncer. In-depth chapters contain fully referenced text as well as detailed tables and images. While the primary audiences for this book are pathologists and pathology residents, the broad examination of diffuse malignant mesothelioma, including its epidemiology, makes this book valuable to radiologists, surgeons, oncologists, and other clinical physicians and their residents as well.Written by experts in the field, Diffuse Malignant Mesothelioma is a concise yet comprehensive resource for clinicians involved in the management of one of the most widely recognized and feared cancers in the world.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 156 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 53,49
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The textprovides the general pathologist, clinician and pulmonary pathologist with a framework on how to work up a case of either non neoplastic or neoplastic lung disease and provide clinically relevant information to all involved in…patient care. The basic understanding of radiologic findings and what they mean or how they are related to clinical and pathologic findings is addressed in detail. The implications of descriptive and diagnostic termsas well as the criteria for diagnosis and limitations of small biopsies is explained. The new entities in lung pathology whether neoplastic or non neoplastic are defined and characterized. The special techniques of pulmonary cytopathology, immunohistochemistry and molecular testingare outlinedand specific algorithms for using them defined.Diagnosis of Small Lung Biopsy: An Integrated Approach will serve as a very useful resource for practicing pathologists, clinicians and those in training with interest in pulmonary pathology and pulmonary medicine.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 120 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 53,49
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Includes specially selected articles that previously appeared in The Chemical Intelligencer magazine published (1995-2000). Excerpts of these Editor's choice chapters chronicle the culture and history of chemistry, featuring great chem…ists and discoverers. Contributors from among the best-known authors of the chemistry community, including numerous Nobel laureates. Features behind the scenes stories about pivotal discoveries, intricacies of laboratory life and interactions among scientists, favorite recipes of renowned researchers, life histories and anecdotes. Chapters detail the human side of science but also present scientific information communicated in an easy-to-perceive and entertaining way. This unique book is not only aimed at chemists but individuals who are interested in the cultural aspects of our science.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 344 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 53,49
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume focuses on cytological, biochemical, and molecular biological methods to identify and examine the function of each nuclear body, with an emphasis on the analysis of long non-coding RNAs. Chapters focus on exploring recent s…tudies that reveal how certain long non protein-coding RNAs accumulate in specific nuclear bodies and regulate the function of the bodies by serving as architectural components or controlling the dynamics of associating protein components. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Nuclear Bodies and Noncoding RNAs: Methods and Protocols serves as a guideline for further study into the sophisticated regulation of gene expression.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 364 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 58,84
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This innovative volume details counseling interventions for secondary students with ADHD and its associated academic and conduct problems, particularly focusing on youth at risk for developing serious disruptive behaviors. It addresses… the continuing debate over counseling for youths with ADHD by identifying key elements common to reputable therapies and suggesting a framework for their successful implementation. The core of the book discusses the Challenging Horizons Program (CHP), a behavior- and solutions-focused approach to counseling adolescents with ADHD that has been studied extensively for more than 15 years. Based on the quality of research, the CHP has been included in the National Registry of Evidence-based Programs and Practices maintained by the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA). Excerpts from actual sessions illustrate typical therapist-client interactions in the CHP, and sample modules from the program's treatment literature expand the book's descriptions of effective hands-on interventions.Counseling skills featured in this book include:Bridging the research-into-practice divide.Establishing a therapeutic alliance with students with ADHD.Developing and implementing interventions for memory, organization, and planning.Enhancing young clients' social skills.Enlisting family members in the intervention process.Working directly with teachers to improve student behaviors.A Practical Guide to Implementing School-Based Interventions for Adolescents with ADHD is an essential resource for researchers, clinicians and related professionals, and graduate students in such disciplines as school and clinical child psychology, social work, educational psychology, psychotherapy and counseling, and learning and instruction.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 228 pp. Englisch.

Lingua: Inglese
Editore: Springer, Humana Okt 2016, 2016
Serie: Undergraduate Texts in Mathematics, Libro 143 di 170. Libro 143 di 170 - Undergraduate Texts in Mathematics
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 58,84
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This text gives a rigorous treatment of the foundations of calculus. In contrast to more traditional approaches, infinite sequences and series are placed at the forefront. The approach taken has not only the merit of simplicity, but st…udents are well placed to understand and appreciate more sophisticated concepts in advanced mathematics. The authors mitigate potential difficulties in mastering the material by motivatingdefinitions, results and proofs. Simple examplesare provided toillustrate new material and exercises are included at the end of most sections. Noteworthy topics include: an extensive discussion of convergence tests for infinite series, Wallis¿s formula and Stirling¿s formula, proofs of the irrationality of ¿ and e and a treatment of Newton¿s method as a special instance of finding fixed points of iterated functions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 488 pp. Englisch.

Lingua: Inglese
Editore: Springer, Humana Okt 2016, 2016
Serie: International Series on Consumer Science, Libro 8 di 11. Libro 8 di 11 - International Series on Consumer Science
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 74,89
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This timely text overviews theories, concepts, and contexts relating to the emerging field of behavioral economics. Research theories and data gathered across psychology, sociology, marketing, finance, and other relevant disciplines ar…e synthesized to identify and elaborate on the defining aspects of consumer economic wellbeing. Against a background of consumer rights and responsibilities, the book discusses consumer phenomena of earning, spending, saving, and borrowing and their contributions to improving (and in some cases to worsening) economic wellness. In addition, the author presents effective ways consumers can be encouraged to navigate key economic environments such as the media, advertising, and the internet, and to change negative financial behaviors.Among the featured topics:Historical perspective on consumer economic wellbeing.Consumer financial capability and economic wellbeing.The role of government in promoting consumer economic wellbeing.Corporate social responsibility.Theories of online shopping and e-banking.Desirable and undesirable consumption behavior.Consumer Economic Wellbeing clarifies issues and provides insights for researchers in the fields of consumer psychology and economics, psychologists and mental health professionals, and policy analysts. It is also useful as a text for college courses in related subjects.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 240 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 74,89
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populati…ons in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 180 pp. Englisch.

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 117,69
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference… for practicing pathologists and may also be used as a reference text by other experts from related fields. The atlas is organised into different chapters based on systemic pathology. Each chapter has illustrations with legends, and the atlas includes some rare examples of unique lesions found during toxicity studies over many years. 300 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume summarizes current cutting-edge methods related to carbohydrate-based vaccines, from the identification of a suitable carbohydrate antigen via the preparation of glycoconjugate vaccines to the characterization of vaccine ca…ndidates for their use in pre-clinical and clinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Carbohydrate-Based Vaccines: Methods and Protocols aims to be a valuable manual that will facilitate research in the field of carbohydrate-based vaccines.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 268 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides a comprehensive overview of quality metrics and methods used to improve quality for all major modalities of CRC screening. It introduces the readers to the evidence of effectiveness behind various CRC screening mod…alities: stool-based tests (Fecal Occult Blood, Fecal Immunochemical and Fecal DNA tests), flexible sigmoidoscopy, colonoscopy and CT colonography. In-depth chapters review the latest guidelines for CRC screening, compare differences among the five major national guidelines, and highlight the need for valid quality and cost indicators. While the main focus of this volume is on colonoscopy, since most quality indicators and analyses have focused on this modality of screening and surveillance, one chapter is devoted to quality indicators of other screening modalities. Differences between process and outcome measures are also highlighted and a small but valid set of recommended national measures are listed.Written by experts in the field, Colorectal Cancer Screening: Quality and Benchmarks is an important and useful resource written for gastroenterologists, primary care physicians, general and colorectal surgeons, family physicians, and investigators with research focus in screening and quality metrics.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 220 pp. Englisch.

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 128,39
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book focuses on the practical aspects of clinical electrophysiology of cardiac arrhythmias in the young. It represents a compilation of the clinical course, electrophysiologic studies, pharmacological management, and transcath…eter ablation therapy in patients from infancy through young adulthood. Topics include the mechanism, ECG characteristics, electrophysiologic findings, treatment, and prognosis of tachyarrhythmias and bradyarrhythmias; specialized subjects including syncope, cardiac pacemakers, and implantable cardiac defibrillators; pharmacology of antiarrhythmic agents; and the roles of allied healthcare professionals in the management of arrhythmias in the young. This revised edition includes new or expanded chapters on the molecular biology mechanisms that underlie the structure and function of the cardiac conduction system; new navigation technologies for detecting cardiac arrhythmias while minimizing radiation exposure; genetic disorders of the cardiac impulse; andsudden cardiac death in the young, particularly athletes. Featuring contributions from practicing clinical cardiac electrophysiologists affiliated with the Michigan Congenital Heart Center at the University of Michigan, Clinical Cardiac Electrophysiology in the Young, Second Edition, is a premier reference for cardiologists, residents, and medical students. 420 pp. Englisch.

Lingua: Inglese
Editore: Humana Okt 2016, 2016
Serie: Respiratory Medicine, Libro 26 di 61. Libro 26 di 61 - Respiratory Medicine
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 128,39
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these dis…orders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care. 492 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 96,29
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book describes the basic principles underlying the generation, coding, transmission and enhancement of speech and audio signals, including advanced statistical and machine learning techniques for speech and speaker recognition wit…h an overview of the key innovations in these areas. Key research undertaken in speech coding, speech enhancement, speech recognition, emotion recognition and speaker diarization are also presented, along with recent advances and new paradigms in these areas.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 356 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume details protocols on detection and analysis of fusion events in various cell types in vitro and in vivo. Additional, protocols aim to facilitate the future highly relevant process of engineering cells for specific purposes,… such as generation of transgenic embryos and development of hybrid cells, in order to tackle specific tasks in cell biology and medicine. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Practical and authoritative, Cell Fusion: Overviews and Methods, Second Edition serves as an ideal reference on cell fusion and laboratory protocols.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 260 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume focuses on detecting different cellular stresses, measuring pathological consequences within the cell, and investigating the role of cellular stresses in select diseases. In addition,this book reviews the crosstalk between…different stress pathways, stress responses during ageing, and targeting stress for regenerative medicine.Written in the highly successfulMethods of Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and instructive,Stress Responses: Methods and Protocolsseeks to aid scientists to further study multiple stress pathways and outcomes triggered by such stresses. In depth knowledge of cellular stress will eventually lead to the development of novel therapeutics to prevent or treat related diseases.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 260 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed volume addresses recent developments in phosphoproteomic techniques with a particular focus on the plant system. Over the recent decades, proteomic methods were refined to study the significance and dynamics of protein ph…osphorylation in various biological contexts. However, working with plant tissue imposes particular challenges to the biologist which are attributed to the rigid cell wall making protein extraction more difficult, the skewed protein abundance with Rubisco as a highly abundant protein and a large central vacuole leading to low protein yield and increased degradative enzyme activity. The methodologies in this book seek to move beyond these issues.Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Practical and authoritative, Plant Phosphoproteomics: Methods and Protocols serves as an ideal reference for researchers investigating this vital area of plant science.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 244 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In this volume expert researchers in the field detail the operations of microchip capillary electrophoresis. Chapters focus on small molecule, biomolecule applications, various detection modes, and sample preparation approaches are des…cribed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Microchip Capillary Electrophoresis Protocol aids scientists in continuing to study microchip capillary electrophoresis.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 212 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume is designed to be a resource of proven techniques and approaches for probing the activities of bacterial, eukaryotic, and archaeal RNA polymerases. This book features a collection of in vitro and in vivo technologies that w…ill permit researchers to purify and probe the position and stability of RNA polymerase complexes at different points of the transcription cycle, analyze the various translocations and intermolecular movements associated with catalysis, define recruitment strategies, probe the roles of transcription factors in each stage of the cycle, highlight conserved and disparate fidelity mechanisms, analyze the resultant transcripts, and study coordination of the nascent mRNA synthesis by the RNA polymerase and mRNA translation by the ribosome. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubles troubleshooting and avoiding known pitfalls.Practical and timely, Bacterial Transcriptional Controls: Methods and Protocols highlights the breadth and depth of techniques that are likely to continue shaping the transcription community in the future.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 356 pp. Englisch.

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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3¿,5¿-monophosphate (cAMP) compartmentalization, that probe relevant protein-protein interactions, that increase t…he spatial and temporal resolution of cAMP signal detection, and that can facilitate integration of the mounting complexity of the information that is becoming available on this signaling system. cAMP, the prototypical intracellular second messenger, regulates a large variety of cellular functions and biological processes, including gene transcription, cell metabolism, proliferation, development, as well as more specialized functions depending on the cell type, so the realization of its extremely complex spatial organization and local regulation is providing novel mechanistic insight into cell physiology and is producing a novel framework for the identification of disease mechanisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Practical and authoritative, cAMP Signaling: Methods and Protocols serves as a vital resource for researchers working in this expanding, complex field.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 232 pp. Englisch.

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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 139,09
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides an overview on design PCR primers for successful DNA amplification. Chapters focus on primer design strategies for quantitative PCR, in silico PCR primer design, and primer design using software. Written in the… highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, PCR Primer Design, Second Edition seeks to aid molecular biology students, researchers, professors and PCR enthusiasts. 228 pp. Englisch.

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EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume contains a collection of relevant information for drug discovery in cell cycle research. Protocols to develop screening assays or to identify novel CDK inhibitors are discussed in the first part of the book. The second part… of the book describes elaborate procedures to evaluate activity and mechanism of action of new and already identified CDK inhibitors. The third part of the book talks about protocols to evaluate metabolomics changes associated to inhibitor treatment. Drug delivery strategies focused on nanoparticle development to provide alternative internalization systems for increasing inhibitor efficacy are also described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, Cyclin-Dependent Kinase (CDK) Inhibitors: Methods and Protocols is a useful tool for scientists interested in this research field.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 240 pp. Englisch.

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EUR 101,64
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume contains a compilation of techniques and laboratory protocols directly related to RNA nano technology and its applications in nano biotechnology and nano medicine. The chapters in this book cover a wide range of research me…thods that can be easily comprehended and carried out in a step-by-step manner by graduate students and postdoctoral fellows from diverse scientific disciplines. Some of the covered topics include various biochemical, biophysical and bioinformatics approaches for analyzing RNA structures and properties; methods to analyze the multi-step assembly process of RNA nano architectures; purification of multifunctional RNA nanoparticles by ultracentrifugation and HPLC; real-time detection of RNA nano constructs in vivo; conjugation of imaging, targeting and therapeutic modules to RNA scaffold; and design and characterization of RNA-protein nanostructures. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubles troubleshooting and avoiding known pitfalls.Cutting-edge and practical, RNA Nanotechnology and Therapeutics: Methods and Protocols propels the field toward new heights by engaging researchers working in the diverse fields of physical, engineering, and life sciences.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 252 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides readers with a comprehensive review of various gene silencing methodologies and its applications. It provides ahistorical overview of gene silencing mechanisms in plants, vectors, and strategies available for plant… gene silencing, practical applications of gene silencing, bioinformatics tools, and other resources. In addition to these review chapters, this book includes methodology for virus-induced gene silencing (VIGS) in various different plant species, understanding plant stress responses using VIGS, miRNA identification, DNA interference, host-induced gene silencing, use of artificial miRNAs for gene silencing, high throughput RNAi, and more. Written in the highly successfulMethods of Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Thorough and practical,Plant Gene Silencing: Methods and Protocolsseeks to aid scientists to further understand functional relevance of target genes using gene silencing methods and use these technologies in commercial plant varieties.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 320 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume covers the techniques necessary for a successful fragment-based drug design project, beginning from defining the problem in terms of preparing the protein model, identifying potential binding sites, and the consideration of… various candidate fragments for simulation. The second part discusses the technical aspects that various methods have used to simulate fragment binding to a target protein by using Monte Carlo, molecular dynamics, and docking algorithms. After simulations, fragments are assembled into molecules using a variety of approaches, which are explored next. A discussion of design strategies and consideration of drug-like properties is included as part of the design process at this stage. Finally, several examples of successful fragment-based drug design projects are presented. Written for the Methods in Molecular Biology series, this work contains the kind of detailed description and implementation advice to encourage success in the lab.Practical and cutting-edge, Fragment-Based Methodsin Drug Discovery takes into account the great accomplishments in the field to provide an ideal guide for researchers continuing to investigate this exciting area of pharmacological study.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 240 pp. Englisch.

Lingua: Inglese
Editore: Humana Press Okt 2016, 2016
Serie: Contemporary Endocrinology, Libro 67 di 84. Libro 67 di 84 - Contemporary Endocrinology
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common…through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, internists, and geneticists. For the last twenty years, there has been a growing recognition worldwide of the importance of managing dyslipidemia for the primary and secondary prevention of atherosclerotic vascular disease, especially coronary heart disease. This has been mainly due to the publication of the guidelines of National Cholesterol Education Program's Adult Treatment Panel and Pediatric Panel from the United States. These guidelines have stimulated generation of similar recommendations from all over the world, particularly Europe, Canada, Australia and Asia. Developed by a renowned group of leading international experts, the book offers state-of-the-art chapters that are peer-reviewed and represent a comprehensive assessment of the field. A major addition to the literature, Dyslipidemias: Pathophysiology, Evaluation and Management is a gold-standard level reference for all clinicians who are challenged to provide the best care and new opportunities for patients with dyslipidemias. 544 pp. Englisch.

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EUR 106,99
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This guide provides a comprehensive review of the full spectrum of hypertension in chronic kidney disease (CKD). Targeted towards the busy practitioner, the focus of this volume is on various therapies and how to lower blood pressure through…lifestyle changes. Specialist patient populations and hypertension and causes of hypertension are also covered in detail. Clinically-focused and authoritative, this resource offers a rationalized approach to diagnosing and treating hypertension in CKD.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 360 pp. Englisch.