Humana press dez 2001 (8 risultati)

Buch. Condizione: Neu. Neuware - Today, implanted artificial prosthetic devices as substitutes for damaged or poorly functioning tissue structures are no longer uncommon when treating a variety of urologic problems and disorders. In Urologic Prostheses: The Complete Practical Guide to Devices, Their Implantation, and Patient Follow Up, a team of authoritative urologic surgeons reviews the latest advances in urologic prosthetic surgery and the patient management techniques needed to successfully implement them. These highly experienced clinicians fully describe each technique and process, providing proven guidelines for patient evaluation prior to its use, its surgical implantation, and postoperative treatment of the patient. The topics expertly covered range from injectable materials used in a variety of circumstances to artificial urinary sphincters, from urethral stents, penile implants, and testicular and penile prostheses, to the newer penile rigidity systems. Comprehensive and authoritative, Urologic Prostheses: The Complete Practical Guide to Devices, Their Implantation, and Patient Follow Up offers both new and experienced practitioners of urologic prosthetic surgery a clear, concise, and practice-oriented survey of all the therapeutic options now available, as well as a guide to today's standard-of-care treatments for these patients.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leading biostatisticians and biomedical researchers describe many of the key techniques used to solve commonly occurring data analytic problems in molecular biology, and demonstrate how these methods can be used in the development of new markers for exposure to a risk factor or for disease outcomes. Major areas of application include microarray analysis, proteomic studies, image quantitation, genetic susceptibility and association, evaluation of new biomarkers, and power analysis and sample size. The use of biostatistical techniques in molecular biology has grown tremendously in recent years and is now essential for the correct interpretation of a wide variety of laboratory studies. In Biostatistical Methods, a panel of leading biostatisticians and biomedical researchers describe all the key techniques used to solve commonly occurring analytical problems in molecular biology, and demonstrate how these methods can identify new markers for exposure to a risk factor, or for determining disease outcomes. Major areas of application include microarray analysis, proteomic studies, image quantitation, determining new disease biomarkers, and designing studies with adequate levels of statistical power. In the case of genetic effects in human populations, the authors describe sophisticated statistical methods to control the overall false-positive rate when many statistical tests are used in linking particular alleles to the occurrence of disease. Other methods discussed are those used to validate statistical approaches for analyzing the E-D association, to study the associations between disease and the inheritance of particular genetic variants, and to examine real data sets. There are also useful recommendations for statistical and data management software (JAVA, Oracle, S-Plus, STATA, and SAS) . Accessible, state-of-the-art, and highly practical, Biostatistical Methods provides an excellent starting point both for statisticians just beginning work on problems in molecular biology, and for all molecular biologists who want to use biostatistics in genetics research designed to uncover the causes and treatments of disease. 228 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein-protein interactions and networks. 212 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this thoroughly revised and updated second edition, a panel of distinguished clinical researchers from around the world takes stock of the wealth of new knowledge about the human spleen and applies it to the pathology and treatment of splenic diseases. This much enriched understanding encompasses the spleen's complex role in immunological defense, the recently defined function of particulate filtration by the spleen, and the structural basis for the functions of the spleen, most particularly the microvasculature around which it is organized. Among the diseases and disorders of the spleen considered in detail are splenomegaly, the consequences and management of hyper- and hyposplenism, and 'dilutional anemia.' Recent advances in splenic surgery are also reviewed, especially those techniques intended to preserve at least partial function while removing the greater part of the organ. 356 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Daniel C. Liebler masterfully introduces the science of proteomics by spelling out the basics of how one analyzes proteins and proteomes, and just how these approaches are then employed to investigate their roles in living systems. He explains the key concepts of proteomics, how the analytical instrumentation works, what data mining and other software tools do, and how these tools can be integrated to study proteomes. Also discussed are how protein and peptide separation techniques are applied in proteomics, how mass spectrometry is used to identify proteins, and how data analysis software enables protein identification and the mapping of modifications. In addition, there are proteomic approaches for analyzing differential protein expression, characterizing proteomic diversity, and dissecting protein-protein interactions and networks. 212 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In this thoroughly revised and updated second edition, a panel of distinguished clinical researchers from around the world takes stock of the wealth of new knowledge about the human spleen and applies it to the pathology and treatment of splenic diseases. This much enriched understanding encompasses the spleen's complex role in immunological defense, the recently defined function of particulate filtration by the spleen, and the structural basis for the functions of the spleen, most particularly the microvasculature around which it is organized. Among the diseases and disorders of the spleen considered in detail are splenomegaly, the consequences and management of hyper- and hyposplenism, and 'dilutional anemia.' Recent advances in splenic surgery are also reviewed, especially those techniques intended to preserve at least partial function while removing the greater part of the organ.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To function properly, neurons must interact with other constituent elements of the brain (e.g., blood supply and myelin), and in fact most diseases of the nervous system involve these nonneuronal components. In The Neuronal Environment: Brain Homeostasis in Health and Disease, leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, ion homeostasis, and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system, which controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in blood-brain barrier function, and inflammation and the neuroimmune system. All these elements are treated in the context of their importance for neurons and the major diseases affecting them. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates for today's neuroscientists, cell biologists, and pharmacologists a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the brain's sole information processing system. 444 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Leading neuroscience researchers offer a fresh perspective on neuronal function by examining all its many components-including their pertubation during major disease states-and relate each element to neuronal demands. Topics range from the dependency of neurons on metabolic supply, as well as on both ion and transmitter homeostasis, to their close interaction with the myelin sheath. Also addressed are the astrocytic signaling system that controls synaptic transmission, the extracellular matrix and space as communication systems, the role of blood flow regulation in neuronal demand and in blood-brain barrier function, and inflammation and the neuroimmune system. Insightful and integrative, The Neuronal Environment: Brain Homeostasis in Health and Disease demonstrates a clear new understanding that neurons do not work in isolation, that they need constant interactions with other brain components to process information, and that they are not the only information processing system in the brain.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 444 pp. Englisch.…