Humana sep 2013 (112 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Proceedings of the 1991 Cryogenic Engineering Conference held in Huntsville, Alabama, June 11-14, 1991. 772 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -e1ectr0ph0re515 (PF6E) wa51nvented 6are1y 10 year5 a90, 6ut ha5 a1ready 6ec0me a maj0r techn14ue m01ecu- 610109y, 1ar w1th hundred5 0f 0ften the ca5e w1th new techn14ue5 the1r 5ta9e5, m05t pu611cat10n5 are 0- dated 6y the t1me they reach pr1nt. F0r rea50n, a num6er 0fthe auth0r5 0f 600k have effect1ve1y 5erved ph0ne c0n5u1tant5 0n PF6E app11cat10n5 f0r 5evera1 year5. 8y n0w, many 0f the maj0r meth0d5 have 6een te5ted and 1mpr0ved that we fee1 a 600k 0f techn14ue5 W0ve Dur1n9 the prepara- Meth0d5, and 7~, tw0 0ther 600k5 rev1ew1n9 PF6E were pu6115hed. H0wever, the pre5ent w0rk the f1r5t t0 1nc0rp0rate the pr0t0c01 5ty1e, the ha11mark 0f the Meth0d51n that ha5 made that appr0ach the pa5t. 1n add1t10n, many 0f the chapter51nc1ude 0n he1pfu11n 5trate91e5 p1ann1n9 exper1ment5. 7he part 0f the 600k c0nta1n5 the0r1e5 and 065ervat10n5 e1uc1dat1n9 the c0mp1ex 6ehav10r 0f DNA dur1n9 PF6E. F0r any 91ven app11cat10n 0f PF6E, the reader p- ceed 6y a a55em611n9 pr0t0c01 fr0m m0re than 0ne chapter (e. 9. , CHEF, preparat10n 0f a9ar05e 610ck5, and mapp1n9 5trate91e5). 70 he1p pr0ce55, th15 we have tr1ed hard t0 pr0v1de an 1ndex and cr055-reference5 that ea5y acce55 t0 the meth0d5. 1t may 6e u5efu1 t0 read chapter5 n0t 1mmed1ate1y re1ated t0 the cat10n m1nd. F0r examp1e, a u5er 0f CHEF may f1nd he1pfu1 h1nt51n the chapter5 0n F16E, 0FA6E, 0r 7AFE. Certa1n meth0d5, 5uch a5 the preparat10n 0f yea5t marker5, are d0ne 50mewhat d1fferent1y d1fferent 1a65, and the reader f1nd 5evera1 pr0- fr0m wh1ch t0 ch005e. 496 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Integral transforms are among the main mathematical methods for the solution of equations describing physical systems, because, quite generally, the coupling between the elements which constitute such a system-these can be the mass points in a finite spring lattice or the continuum of a diffusive or elastic medium-prevents a straightforward 'single-particle' solution. By describing the same system in an appropriate reference frame, one can often bring about a mathematical uncoupling of the equations in such a way that the solution becomes that of noninteracting constituents. The 'tilt' in the reference frame is a finite or integral transform, according to whether the system has a finite or infinite number of elements. The types of coupling which yield to the integral transform method include diffusive and elastic interactions in 'classical' systems as well as the more common quantum-mechanical potentials. The purpose of this volume is to present an orderly exposition of the theory and some of the applications of the finite and integral transforms associated with the names of Fourier, Bessel, Laplace, Hankel, Gauss, Bargmann, and several others in the same vein. The volume is divided into four parts dealing, respectively, with finite, series, integral, and canonical transforms. They are intended to serve as independent units. The reader is assumed to have greater mathematical sophistication in the later parts, though. 504 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 332 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 320 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Despite the urbanization of the United States, the rural population exceeds 60 million, and the provision of health services to these people remains a difficult problem. This volume addresses one crucial aspect of that problem-the task of attracting physicians to rural medical practice. It does this by carefully analyzing the special health problems and the general features of rural society in which the young doctor would be working. Rural health needs have been recognized in America for wen over a century. In response, many organized health programs have, in fact, improved the situation. Compared to 1930, the present coverage of rural counties by public health agencies has been greatly extended. Thanks to the Hill-Burton Act of 1946, the availability of general hospital beds has become virtually equalized among the states with varying degrees of rurality. Federally subsidized and locally organized health programs are serving migratory workers, American Indians, the people of Appalachia, and other rural groups. Voluntary health insurance covers millions of rural families, even though the extent of this economic protection is less than among urban families. Medicare helps to protect the rural aged, as it does the urban. Medicaid finances health services for the rural poor far more effectively than the purely local welfare programs of 1930. There is no question, then, about the improvement in rural health resources and services in America over the last 50 years. 172 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 276 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 132 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Advanced Study Institute on 'Path Integrals and Their Applications in Quantum, Statistical, and Solid State Physics' was held at the University of Antwerpen (R.U.C.A.), July 17-30, 1977. The Institute was sponsored by NATO. Co-sponsors were: A.C.E.C. (Belgium), Agfa-Gevaert (Belgium), l'Air Li~uide BeIge (Belgium), Be1gonucleaire (Belgium), Bell Telephone Mfg. Co. (Belgium), Boelwerf (Belgium), Generale BankmaatschappiJ (Belgium), I.B.M. (Belgium), Kredietbank (Belgium), National Science Foundation (U.S.A.), Siemens (Belgium). A total of 100 lecturers and partici pants attended the Institute. The development of path (or functional) integrals in relation to problems of stochastic nature dates back to the early 20's. At that time, Wiener succeeded in obtaining the fundamental solution of the diffusion e~uation using Einstein's joint probability of finding a Brownian particle in a succession of space intervals during a corresponding succession of time intervals. Dirac in the early 30's sowed the seeds of the path integral formulation of ~uantum mecha nics. However, the major and decisive step in this direction was taken with Feynman's works in ~uantum and statistical physics, and quantum electrodynamicso The applications now extend to areas such as continuous mechanics, and recently functional integration methods have been employed by Edwards for the study of polymerized matter. 528 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The extensive development of electronics and automation equip ment defines the scientific and technical significance of all types of high-density energy converters that are used in electronic and automatic equipment. A powerful pulsed discharge in gas is one type of conversion of electrical energy into extremely intense optical radiation. In order to characterize the possibilities inherent in such a discharge, it suffices to recall that high-power lasers were first developed by using flashlamps based on precisely this kind of discharge. The correct use of existing types of flashlamps, work toward developing new types of flashlamps, and the solution of new problems by using such flashlamps require a knowledge of the physical processes that occur in them and the relationship between their technical characteristics and their design data and power-supply parameters. An acquaintance with the variety of existing flashlamps and the cir cuits used in the equipment employing them also is needed. 476 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I Neo-Kraepelinian Approach to Classification.- 1 Kraepelin and His Influence On Modern Classification.- 2 The Neo-Kraepelinian Movement In American Psychiatry.- 3 The Neo-Kraepelinian Movement and the Medical Model.- 4 Diagnostic Reliability.- 5 DMS-III.- II Quantitative Approaches to Classification.- 6 An Overview of Multivariate Models and Methods.- 7 Factor Analysis and Psychopathology.- 8 Cluster Analysis and the Classification of Patients.- Epilogue.- Appendix I. Classifications of Psychopathology.- Appendix II. Cluster-Analytic Studies of Psychopathology.- References.- Author Index. 348 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -ADHD as a Model of Brain-Behavior RelationshipsLeonard F. Koziol, Deborah Ely Budding, and Dana Chidekel Series Title: Springer Briefs in NeuroscienceSubseries: The Vertically Organized Brain in Theory and PracticeIt's been a basic neurological given: the brain does our thinking, and has evolved to do the thinking, as controlled by the neocortex. In this schema, all dysfunction can be traced to problems in the brain's lateral interactions. But in scientific reality, is this really true Challenging this traditional cortico-centric view is a body of research emphasizing the role of the structures that control movement-the brain's vertical organization-in behavioral symptoms. Using a well-known, widely studied disorder as a test case, ADHD as a Model of Brain-Behavior Relationships offers an innovative framework for integrating neuroscience and behavioral research to refine diagnostic process and advance the understanding of disorders. Identifying a profound disconnect between current neuropsychological testing and the way the brain actually functions, this revision of the paradigm critiques the DSM and ICD in terms of the connectedness of brain structures regarding cognition and behavior. The authors argue for a large-scale brain network approach to pathology instead of the localizing that is so common historically, and for an alternate set of diagnostic criteria proposed by the NIMH. Included in the coverage:The diagnosis of ADHD: history and context.ADHD and neuropsychological nomenclatureResearch Domain Criteria: a dimensional approach to evaluating disorderThe development of motor skills, executive function, and a relation to ADHDThe role of the cerebellum in cognition, emotion, motivation, and dysfunctionHow large-scale brain networks interactHeralding a more accurate future of assessment, diagnosis, and treatment of neurodevelopmentaldisorders, ADHD as a Model of Brain-Behavior Relationships represents a major step forward for neuropsychologists, child psychologists, and psychiatrists, or any related profession interested in a neuroscientific understanding of brain function. 104 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -By focusing on quadratic numbers, this advanced undergraduate or master's level textbook on algebraic number theory is accessible even to students who have yet to learn Galois theory. The techniques of elementary arithmetic, ring theory and linear algebra are shown working together to prove important theorems, such as the unique factorization of ideals and the finiteness of the ideal class group. The book concludes with two topics particular to quadratic fields: continued fractions and quadratic forms. The treatment of quadratic forms is somewhat more advanced than usual, with an emphasis on their connection with ideal classes and a discussion of Bhargava cubes.The numerous exercises in the text offer the reader hands-on computational experience with elements and ideals in quadratic number fields. The reader is also asked to fill in the details of proofs and develop extra topics, like the theory of orders. Prerequisites include elementary number theory and a basic familiarity with ring theory. 212 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There have been many important advances in our understanding of biological membrane structure and function over the last decade. Much of this progress has been driven by the development of new techniques for studying membrane components and their interactions. Tradition ally, the investigation of membranes has largely occurred within the domains of biochemistry, physical chemistry, and cell biology; but many of the most significant advances have resulted from an expansion into other disciplines, such as molecular biology, immunology, and the clinical sciences. In these two volumes we have attempted to bring together some of these techniques-to combine the old and the new. Biomembrane Protocols: II. Architecture and Function is concerned exclusively with the architecture and activities of membranes, whereas the companion volume, Biomembrane Protocols: I. Isolation and Analysis, deals with their isolation and compositional analysis. The aim of each chapter is to provide detailed technical and meth odological information that will allow the reader to perform the tech nique successfully, without the need to consult other texts. Detailed reviews of membrane structure and function are not included, except where they are relevant to the choice or efficacy of a particular proce dure. In addition to Materials and Methods sections, each chapter has a Notes section that explains the reasons for taking certain steps and pro vides practical tips for applying the techniques to other systems. 380 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Distributions in the Physical and Engineering Sciences is a comprehensive exposition on analytic methods for solving science and engineering problems. It is written from the unifying viewpoint of distribution theory and enriched with many modern topics which are important for practitioners and researchers. The goal of the books is to give the reader, specialist and non-specialist, useable and modern mathematical tools in their research and analysis.Volume 2: Linear and Nonlinear Dynamics of Continuous Media continues the multivolume project which endeavors to show how the theory of distributions, also called the theory of generalized functions, can be used by graduate students and researchers in applied mathematics, physical sciences, and engineering. It contains an analysis of the three basic types of linear partial differential equations--elliptic, parabolic, and hyperbolic--as well as chapters on first-order nonlinear partial differential equations and conservation laws, and generalized solutions of first-order nonlinear PDEs. Nonlinear wave, growing interface, and Burger¿s equations, KdV equations, and the equations of gas dynamics and porous media are also covered.The careful explanations, accessible writing style, many illustrations/examples and solutions also make it suitable for use as a self-study reference by anyone seeking greater understanding and proficiency in the problem solving methods presented. The book is ideal for a general scientific and engineering audience, yet it is mathematically precise.Features Application oriented exposition of distributional (Dirac delta) methods in the theory of partial differential equations. Abstract formalism is keep to a minimum. Careful and rich selection of examples and problems arising in real-life situations. Complete solutions to all exercises appear at the end of the book. Clear explanations, motivations, and illustration of all necessary mathematical concepts.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 436 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Engineering Viscoelasticity covers all aspects of the thermo- mechanical response of viscoelastic substances that a practitioner in the field of viscoelasticity would need to design experiments, interpret test data, develop stress-strain models, perform stress analyses, design structural components, and carry out research work. The material in each chapter is developed from the elementary to the esoteric, providing the background in mathematics and mechanics that are central to understanding the subject matter being presented. This book also examines how viscoelastic materials respond to the application of loads, and provides practical guidelines to use them in the design of commercial, military and industrial applications.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 392 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Dropwise Condensation on Textured Surfaces presents a holistic framework for understanding dropwise condensation through mathematical modeling and meaningful experiments. The book presents a review of the subject required to build up models as well as to design experiments. Emphasis is placed on the effect of physical and chemical texturing and their effect on the bulk transport phenomena. Application of the model to metal vapor condensation is of special interest. The unique behavior of liquid metals, with their low Prandtl number and high surface tension, is also discussed. The model predicts instantaneous drop size distribution for a given level of substrate subcooling and derives local as well as spatio-temporally averaged heat transfer rates and wall shear stress.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 160 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -From September 19-29, a NATO Advanced Study Institute on Non destructive Evaluation of Semiconductor Materials and Devices was held at the Villa Tuscolano in Frascati, Italy. A total of 80 attendees and lecturers participated in the program which covered many of the important topics in this field. The subject matter was divided to emphasize the following different types of problems: electrical measurements; acoustic measurements; scanning techniques; optical methods; backscatter methods; x-ray observations; accele rated life tests. It would be difficult to give a full discussion of such an Institute without going through the major points of each speaker. Clearly this is the proper task of the eventual readers of these Proceedings. Instead, it would be preferable to stress some general issues. What came through very clearly is that the measurements of the basic scientists in materials and device phenomena are of sub stantial immediate concern to the device technologies and end users.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 796 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Industrial Crystallization Symposia have been organized by the Crystallization Research Group at the Czechoslovak Research Institute for Inorganic Chemistry, Usti nad Labem, since 1960. Over the years, the increasing popularity of the unit operation of crystallization has been clearly demonstrated by the steady increase in numbers of both the papers presented and the attendances at the meetings. The 6th Symposium (1-3 September 1975) was organized jointly with the European Federation of Chemical Engineering Working Party on Crystallization, and the 44 papers presented were arranged into four sessions - A: Secondary Nucleation, B: Crystal Growth Kinetics, C: Crystal Habit Modification, D: Crystallizer Design, E: Indus trial Crystallizer Operation and Case Studies. The same groupings are preserved in this edited version of the proceedings. This is the first time that the Industrial Crystallization Symposium papers have appeared in one volume. After the 5th (1972) Symposium, authors we.re encouraged to submit their papers to an international journal specializing in crystallization. However, the results were not altogether satisfactory in that less than one third of the papers presented at the meeting were offered for consideration. This time, therefore, the organizing committee decided to attempt to keep the papers together by making arrangements for their pUblication by Plenum Press.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 488 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Electrophoretic Techniques.- Field-Inversion Gel Electrophoresis.- Resolving Multimegabase DNA Molecules Using Contour-Clamped Homogeneous Electric Fields (CHEF).- Separation and Size Determination of DNA over a 10-,200 kbp Range.- PFGE Using Double-Inhomogeneous Fields or Orthogonal Field-Alternating Gel Electrophoresis (OFAGE).- Transverse Alternating-Field Electrophoresis.- Rotating Field Gel Electrophoresis (ROFE).- Preparation, Manipulation, and Pulse Strategy for One-Dimensional Pulsed-Field Gel Electrophoresis (ODPFGE).- Auxiliary Methods.- Preparation, Restriction, and Hybridization Analysis of Mammalian Genomic DNA for Pulsed-Field Gel Electrophoresis.- Encapsulation of Cells in Agarose Beads.- Preparation and Separation of Intact Chromosomes of Vertebrates by One-Dimensional Pulsed-Field Gel Electrophoresis (ODPFGE).- Isolation of Plant DNA for Pulsed-Field Gel Electrophoresis.- Methyltransferases as Tools to Alter the Specificity of Restriction Endonucleases.- Desktop Digital Imaging.- Biological Applications.- Bacterial Genome Mapping by Two-Dimensional Pulsed-Field Gel Electrophoresis (2D-PFGE).- Protozoan Genomes.- Construction of Yeast Artificial Chromosome Libraries by Pulsed-Field Gel Electrophoresis.- Analysis of Yeast Artificial Chromosome Clones.- Strategies for Mapping Large Regions of Mammalian Genomes.- Two-Dimensional DNA Electrophoresis (2D-DE) for Mammalian DNA.- Pulsed-Field and Two-Dimensional Gel Electrophoresis of Long Arrays of Tandemly Repeated DNA.- Construction of Lambda Libraries from Large PFGE Fragments.- In-Gel Detection of DNA.- Theories and Observations.- Theories of Pulsed-Field Gel Electrophoresis.- The Dynamics of DNA Gel Electrophoresis.- Orientation of the Agarose Matrix by Pulsed Electric Fields.- Reptation Theory ofPulsed Electrophoresis and Trapping Electrophoresis.- Elastic Bag Model of One-Dimensional Pulsed-Field Gel Electrophoresis (ODPFGE).Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 496 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The original motivation for the development of digital computers was to make it possible to perform calculations that were too large to be attempted by a human being without serious likelihood of error. Once the users found that they could achieve their initial aims, they then wanted to go into greater detail, and to solve still bigger problems, so that the demand for extra computing power has continued unabated, and shows no sign of slackening. This book is an attempt to describe some of the more important techniques used today, or likely to be used in the near future, to perform arithmetic within the computing machine. There are, at present, few books in this field. Most books on computer design cover the more elementary methods, and some go into detail on one or two more ambitious units. Space does not allow more. In this text the aim has been to fill this gap in the literature. In selecting the topics to be covered, there have been two main aims: first, to deal with the basic procedures of arithmetic, and then to carry on to the design of more powerful units; second, to maintain a strictly practical approach. The number of mathematical formulae has been kept to a minimum, and the more complex ones have been eliminated, since they merely serve to obscure the essential principles.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 152 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Whereas conventional maps can be expressed as outward-expanding formulae with well-defined central features and relatively poorly defined edges, Constant Scale Natural Boundary (CSNB) maps have well-defined boundaries that result from natural processes and thus allow spatial and dynamic relationships to be observed in a new way useful to understanding these processes. CSNB mapping presents a new approach to visualization that produces maps markedly different from those produced by conventional cartographic methods.In this approach, any body can be represented by a 3D coordinate system. For a regular body, with its surface relatively smooth on the scale of its size, locations of features can be represented by definite geographic grid (latitude and longitude) and elevation, or deviation from the triaxial ellipsoid defined surface. A continuous surface on this body can be segmented, its distinctive regional terranes enclosed, and their inter-relationships defined, by using selected morphologically identifiable relief features (e.g., continental divides, plate boundaries, river or current systems). In this way, regions of distinction on a large, essentially spherical body can be mapped as two-dimensional ¿facets¿ with their boundaries representing regional to global-scale asymmetries (e.g., continental crust, continental and oceanic crust on the Earth, farside original thicker crust and nearside thinner impact punctuated crust on the Moon). In an analogous manner, an irregular object such as an asteroid, with a surface that is rough on the scale of its size, would be logically segmented along edges of its impact-generated faces.Bounded faces are imagined with hinges at occasional points along boundaries, resulting in a foldable ¿shape model.¿ Thus, bounded faces grow organically out of the most compelling natural features. Obvious boundaries control the map¿s extremities, and peripheral regions are not dismembered or grosslydistorted as in conventional map projections. 2D maps and 3D models grow out of an object¿s most obvious face or terrane ¿edges,¿ instead of arbitrarily by imposing a regular grid system or using regularly shaped facets to represent an irregular surface.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 128 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Underlying the design of the Handbook of Psychopharmacology is a prejudice that the study of drug influences on the mind has advanced to a stage where basic research and clinical application truly mesh. These later volumes of the Handbook are structured according to this conception. In certain volumes, groups of drugs are treated as classes with chapters ranging from basic chemistry to clinical application. Other volumes are assembled around topic areas such as anxiety or affective disorders. Thus, besides chapters on individual drug classes, we have included essays addressing broad areas such as 'The Limbic-Hypothalamic-Pituitary-Adrenal System and Human Be havior' and 'Peptides and the Central Nervous System. ' Surveying these diverse contributions, one comes away with a sentiment that, far from being an 'applied' science borrowing from fundamental brain chemistry and physiology, psychopharmacology has instead provided basic researchers with the tools and conceptual approaches which now are advancing neurobiology to a central role in modern biology. Especially gratifying is the sense that, while contributing to an understanding of how the brain functions, psychopharmacology is a discipline whose fruits offer genuine help to the mentally ill with promises of escalating benefits in the future. L. L. 1. S. D. I. S. H. S. VII CONTENTS CHAPTER 1 Drug Self-Administration: An Analysis of the Reinforcing Effects of Drugs Roy PICKENS, RICHARD A. MEISCH, and TRAVIS THOMPSON 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I 2. Methods of Self-Administration . . . . . . . . . . . . . . . . . . . . . . . 3 3. Establishing Drugs as Reinforcers. . . . . . . . . . . . . . . . . . . . . . 4 4. Characteristics of Self-Administration . . . . . . . . . . . . . . . . . 7 4. 1. Ethanol. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 440 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book is the report of a collaborative effort. Frank Porporino and I arrived at the starting point for our work together by very different routes. Originally trained as an experimental psychologist, I had become in creasingly restive within the confines of the laboratory, and spent a sab batical year in the equivalent of a clinical internship. I then spent some time as a part-time consultant in a local penitentiary. Most of my time in the institution was spent with inmates with a variety of problems, probably about 50 individuals over the course of a year. Although this was far fewer than a full-time psychologist in the system might encounter, it served as a quick cram course on problem prisoners and prisoner problems. Very quickly my stereotypes about convicts were shown to be virtually useless. I learned that the criminal classes included all levels of society, and that the behavior of prisoners was the same as that of other human beings in a difficult environment.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 224 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text provides a masterful and systematic treatment of all the basic analytic and geometric aspects of Bergman's classic theory of the kernel and its invariance properties. These include calculation, invariance properties, boundary asymptotics, and asymptotic expansion of the Bergman kernel and metric. Moreover, it presents a unique compendium of results with applications to function theory, geometry, partial differential equations, and interpretations in the language of functional analysis, with emphasis on the several complex variables context. Several of these topics appear here for the first time in book form. Each chapter includes illustrative examples and a collection of exercises which will be of interest to both graduate students and experienced mathematicians.Graduate students who have taken courses in complex variablesand have a basic background in real and functional analysis will find this textbook appealing. Applicable courses for either main or supplementary usage include those in complex variables, several complex variables, complex differential geometry, and partial differential equations. Researchers in complex analysis, harmonic analysis, PDEs, and complex differential geometry will also benefit from the thorough treatment of the many exciting aspects of Bergman's theory. 308 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The majority of all proteins undergo posttranslational modifications that significantly alter their physical and chemical properties, including their folding and conformation distribution, their stability, and, consequently, their activity and function. In Posttranslational Modifications of Proteins: Tools for Functional Proteomics, Christoph Kannicht and a panel of highly experienced researchers describe readily reproducible methods for detecting and analyzing the most important of these modifications, particularly with regard to protein function, proteome research, and the characterization of pharmaceutical proteins. Among the methods presented are those for analyzing the assignment of disulfide bond sites in proteins, protein N-glycosylation and protein O-glycosylation, and oligosaccharides present at specific single glycosylation sites in a protein. Additional powerful techniques facilitate the analysis of glycosylphosphatidylinositols, lipid modifications, protein phosphorylation and sulfation, protein methylation and acetylation, a-amidation, g-glutamate, isoaspartate, and lysine hydroxylation. Comprehensive and state-of-the-art, Posttranslational Modifications of Proteins: Tools for Functional Proteomics serves as a highly practical guide for all investigators of protein structure-function relationships not only in chemical and pharmaceutical research, but also throughout the rapidly growing field of functional proteomics. 336 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of Hematologic Malignancies: Methods and Techniques is to review those methods most useful for the diagnosis and subsequent mana- ment of hematologic malignancies. The scope of coverage is intentionally broad, ranging from routine procedures to highly sophisticated methods not currently offered by most clinical laboratories. The latter methods were selected especially to bring into focus recent advances in molecular biology that, since they provide us with strong tools for assessing the outcome of upcoming therapeutic modalities intent on disease eradication, are expected to impact the future diagnosis and management of these diseases. Thus, the c- mon thread among all chapters is clinical relevance, whether sanctioned by past experience or by the expectation that seemingly esoteric research techniques of today will prove clinically valuable in the future. Hematologic Malignancies: Methods and Techniques is primarily a compilation of methods presented in sufficient detail-by authors with extensive expertise in their field-to serve not only as a reference for seasoned research and clinical laboratory pers- nel, but also as a guide for the less experienced. Moreover, the contributing authors also discuss the pathophysiologic bases and the diagnostic usefulness that underscore each method's clinical relevance. Thus, this volume should be also valuable to clinicians-especially hematologists, oncologists, and path- ogists-often bewildered by an ever increasing flow of new scientific inf- mation, the practical application of which is often either not clearly disclosed or difficult to discern. 380 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Colin Graham and a team of leading investigators and expert clinical scientists update the acclaimed first edition with a collection of powerful, up-to-date PCR-based methods for DNA sequencing, many suitable for human genome sequencing and mutation detection in human disease. This second edition offers new material on automated DNA sequencers, capillary DNA sequencers, heterozygote mutation detection, web-based sequencing databases and genome sequencing sites, and the human genome project. State-of-the-art and highly practical, DNA Sequencing Protocols, 2nd Edn. constitutes an essential laboratory handbook for geneticists and molecular biologists, offering concise, easy-to-follow methods that will work and impact today's genome sequencing projects. 260 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Membrane proteins and membrane lipids form complex interactive systems that are highly dynamic and able to be studied only by combinations of different in vivo and in vitro techniques. In Membrane Biogenesis: Methods and Protocols, experts in the field present a broad collection of methods to study the biogenesis and function of cellular membranes. Beginning with how membrane lipids or membrane proteins can be studied, this detailed volume continues with sections covering different procedures to investigate the interaction of membrane proteins among each other or with membrane lipids, methods to study the biogenesis of membrane proteins and the dynamics of organelles, as well as protocols for the analyses of the functions or complex organization of membrane proteins. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Extensive and easily applicable, Membrane Biogenesis: Methods and Protocols provides readers with a comprehensive but still concise collection including both basic protocols of rather general application and more specialized methods for specific and novel techniques. 420 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Wound Regeneration and Repair: Methods and Protocols, expert researchers in the field detail classical and cutting-edge methods for studying wound healing and regeneration. These techniques include cellular and molecular methods, genetic approaches, surgical procedures, clinical advances, drug discovery and delivery modalities, animal and humanized models and new applications in the treatment of pathological wounds in a variety of organs and tissues. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, a detailed list of the necessary materials and reagents for each procedure, step-by-step, reproducible laboratory protocols, and a set notes, developed by the authors, for troubleshooting and avoiding known pitfalls. Authoritative and practical, Wound Regeneration and Repair: Methods and Protocols seeks to aid scientists and entrepreneurs in their further study of technologies, models, techniques, and critical new areas and approaches to clinical and commercial translation of research. 608 pp. Englisch.…