Humana sep 2026 (38 risultati)

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This new edition offers a clinical guide for caring for aging patients with lung disease. Persons over the age of 65 remain the fastest growing segment of the population. According to the 2020 Census, 55.8 million people in the United States were aged 65 or older. This number is expected to increase to 66 million by the year 2050. This accounts for 16.8% of the total population and was an increase of 38.6% from 2010. There are many pulmonary conditions among the current leading causes of death in older persons, including lung cancer, chronic respiratory diseases and infections such as influenza, COVID-19, and bacterial pneumonia. With limited numbers of geriatricians caring for older persons, this will be the purview of all physicians.Since the first edition, there have been advancements in many aspects of caring for older patients with lung disease. This book presents a complete update of the field. Chapters now cover topics such as immune senescence and the lung microbiome. There have additionally been major advances in diagnosis and available treatments for patients with lung cancer, interstitial lung disease, bronchiectasis, COPD, and pulmonary hypertension. The importance of palliative care and cognitive health for aging patients are also carefully considered in this new edition.This is an ideal guide for all pulmonary medicine professionals. 467 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume covers methods to study protein modification by the Small Ubiquitin-like Modifier (SUMO) family of proteins, post-translational modifiers with essential roles in physiology and pathology. The book explores methods to detect SUMOylated proteins, identify SUMO modified sites, characterize the deposition and removal of these modifications, and explore how SUMO modifies protein-protein interactions both in vitro and in cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and practical, SUMO: Methods and Protocols serves as an ideal guide for researchers seeking the most relevant and cutting-edge technologies to dissect protein SUMOylation. 216 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides an overview of RNA-based technologies, covering their mechanisms, therapeutic applications, and challenges. Chapters explore therapeutic RNAs, RNA stability, mRNA vaccine formulation, strategies to overcome immunogenicity, delivery hurdles, mRNA-based cancer immunotherapy, CAR and TCR T cell therapies, and RNA interference. Additional chapters examine RNA delivery systems such as lipid nanoparticles, nanotubular structures and extracellular vesicles. Written in the highly successful Methods in Molecular Biology series format, the chapters include brief introductions tothe material, lists of necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and a Notes section which highlightstips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, RNA Therapeutics: From siRNA to mRNA Innovations aims to be comprehensive guide forresearchers in the field. 504 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This collection explores advances in genome sequencing and analysis tools for the understanding ofinsect genomes and hence their biology. Beginning with obtaining a high-quality genome assembly using the latest sequencing data, the book continues with the identificationof genome variability including single nucleotide polymorphisms and genomic inversions,and the annotation of insect genomes through genes, transposable elements, and piRNA clusters. Notably, chapters also delveinto downstream analyses, such as the evolution of gene families and phylogenetics,molecular biology protocols pertinent to the study of insects, as well as CRISPR-era genome editing tools to manipulate non-model insects. Written for the highly successfulMethods in Molecular Biologyseries, chapters include the kind of detailed implementation advice to ensure success in the laboratory. Authoritative and practical,Insect Genomics: Methods and Protocolsserves as an ideal source for state-of-the-art methods and comprehensive reviews to help researchers design and implement their own studies. 416 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The book details methods and protocols on fruit and vegetable waste management. Chapters include multidimensional topics on circular economy, biorefinery approach of fruit and vegetable processing wastes; bioconversion of fruit and vegetable processing wastes into biofuel, biogas, fermentable sugar, electricity, briquette, biochar, activated carbon, bioremediation for bio-solvent and byproducts processing, valorization of fruit, and vegetable processing waste to develop value-added products. Written in the format of theMethods and Protocols in Food Scienceseries, chapters list necessary materials and methods for readily reproducible protocols.Authoritative and cutting-edge,Fruit and Vegetable Processing Wastes and By-products: Utilization and Future Prospects aims to be comprehensive guide for researchers in the field. 203 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume discusses that latest cell therapy methods for neurological diseases using bone marrow-derived mononuclear cells, mesenchymal stem cells, dental pulp stem cells, adipose-derived stem cells, cord blood cells, and amnion cells. The chapters in this book also cover specific diseases such as cerebral infarction, spinal cord injury, amyotrophic lateral sclerosis, neuropathic pain, and hypoxic-ischemic encephalopathy. Each chapter includes a detailed description of the protocol for preparing the cells used, the method for producing the animals used, and the characteristics of patients with each disease, as well as an explanation of the behavioral experiments, molecular biochemical experiments, and other methods required to evaluate the effectiveness of the treatment. In theNeuromethodsseries style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and practical,Regenerative Cellular Therapies for Neurological Diseasesis a valuable resource for graduate students and postdoctoral researchers who want to learn more about this field and develop cell therapies for neurological diseases. 172 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This extensive volume explores the phenomena of chaotic genomic rearrangements, known as chromoanagenesis, their formation mechanisms, and the state-of-the-art techniques used to detect them. The book delves into the potential impact of chromoanagenesis on cancers and congenital diseases, as well as its broader implications for genomic evolution and human health through a variety of cutting-edge methodologies. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Chromoanagenesis: Methods and Protocols serves as an ideal guide to the mechanisms and consequences of chromoanagenesis and a resource for researchers and clinicians seeking to explore the cutting-edge techniques and models used to study this phenomenon.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 660 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This collection explores advances in genome sequencing and analysis tools for the understanding of insect genomes and hence their biology. Beginning with obtaining a high-quality genome assembly using the latest sequencing data, the book continues with the identification of genome variability including single nucleotide polymorphisms and genomic inversions, and the annotation of insect genomes through genes, transposable elements, and piRNA clusters. Notably, chapters also delve into downstream analyses, such as the evolution of gene families and phylogenetics, molecular biology protocols pertinent to the study of insects, as well as CRISPR-era genome editing tools to manipulate non-model insects. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice to ensure success in the laboratory. Authoritative and practical, Insect Genomics: Methods and Protocols serves as an ideal source for state-of-the-art methods and comprehensive reviews to help researchers design and implement their own studies.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 428 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume explores the practical application of quantum mechanical (QM) methods in modern drug design. Its chapters cover methodological developments, integration with molecular dynamics and artificial intelligence, applications to diverse target classes and modalities, and perspectives on automation and high-throughput deployment. The book is intended for a broad readership, including computational and medicinal chemists, structural biologists, pharmacologists, and researchers working at the interface of physics, chemistry, and drug design. Written for the highly successful Methods in Molecular Biology series, the chapters provide the detailed guidance necessary for successful implementation of these techniques.Expansive and cutting-edge, Quantum Mechanics Applications in Drug Design serves as both an authoritative reference and a practical guide for scientists seeking to harness quantum mechanical methods to accelerate and improve the design of new therapeutics.Springer Nature Customer Service Center GmbH, Europaplatz 3, 69115 Heidelberg 364 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed collection explores methods that leverage and extend the capabilities of synthetic biology, guiding the reader from foundational molecular manipulations to complex cellular applications. Beginning with chapters on engineering proteins and enzymes, the book continues by covering methods for the repurposing of viral architectures, from bacteriophages to virus-like particles, as programmable nanoscaffolds, CRISPR-driven genome engineering, directed evolution and selection, as well as the synthesis of functional genetic libraries and the groundbreaking technology of biological 'memory,' where a cell's history is permanently recorded into its DNA. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and practical, Biological Macromolecule Engineering Technologies serves as an ideal guide for researchers looking to drive the next wave of discovery in biological macromolecule engineering and address some of humanity's most pressing challenges in health, energy, and manufacturing.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 336 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The book details methods and protocols on fruit and vegetable waste management. Chapters include multidimensional topics on circular economy, biorefinery approach of fruit and vegetable processing wastes; bioconversion of fruit and vegetable processing wastes into biofuel, biogas, fermentable sugar, electricity, briquette, biochar, activated carbon, bioremediation for bio-solvent and byproducts processing, valorization of fruit, and vegetable processing waste to develop value-added products. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols.Authoritative and cutting-edge, Fruit and Vegetable Processing Wastes and By-products: Utilization and Future Prospects aims to be comprehensive guide for researchers in the field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume discusses that latest cell therapy methods for neurological diseases using bone marrow-derived mononuclear cells, mesenchymal stem cells, dental pulp stem cells, adipose-derived stem cells, cord blood cells, and amnion cells. The chapters in this book also cover specific diseases such as cerebral infarction, spinal cord injury, amyotrophic lateral sclerosis, neuropathic pain, and hypoxic-ischemic encephalopathy. Each chapter includes a detailed description of the protocol for preparing the cells used, the method for producing the animals used, and the characteristics of patients with each disease, as well as an explanation of the behavioral experiments, molecular biochemical experiments, and other methods required to evaluate the effectiveness of the treatment. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and practical, Regenerative Cellular Therapies for Neurological Diseases is a valuable resource for graduate students and postdoctoral researchers who want to learn more about this field and develop cell therapies for neurological diseases.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed volume navigates the journey from a promising chemical entity to a potential therapeutic agent in cancer research through systematic and rigorous protocols across a spectrum of increasingly sophisticated models. Beginning with foundational in vitro assays for assessing cytotoxicity and antiproliferative effects, the book continues by covering mechanisms of action studies, advanced 2D and 3D culture models for the tumor microenvironment and cellular architecture involved in modulating drug response and resistance, in vivo antitumor and efficacy models, as well as immunology and inflammation-related assays and forward-looking clinical studies for cancer research. Written for the Springer Protocols Handbooks series, chapters include the kind of precise implementation advice and methodological clarity that leads to success in advancing the current state of the research.Comprehensive and practical, Advanced Protocols in Cancer Research: Translational Models for Antitumor and Anticancer Drug Discovery serves as a valuable resource for fostering methodological precision and accelerating the translation of scientific discovery into effective cancer therapies.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 344 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume discusses the current models and latest methodologies used to explore key questions in transfusion medicine. The chapters in this book cover topics such as mouse models of platelet alloimmunization refractoriness and immune thrombocytopenia; analysis of biotinylated red cell blood cells following transfusion; impact of intravascular hemolysis on erythropoiesis in sickle cell disease; western blot detection of blood group A and B antigens; and the role of marginal zone B cells in FVIII inhibitor development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and comprehensive, Methods in Transfusion Medicine is a valuable resource for all researchers interested in learning more about this field and leading us closer to optimal transfusion practice.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 864 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This fourth edition volume builds on the strengths of previous editions, with examples of how AI is being used in innovative ways to process, interpret, and understand biochemical and related data.Chapters cover a wide range of topics, from bacteriophage genomics, bioimage analysis, and the prediction of the properties of antibodies, to biomedical prediction, disease prevention, label-free imaging, and more. Further chapters focus on some of the AI methods themselves that lie at the heart of such applications, including machine learning and ensemble learning, biological networks, probabilistic neural networks, graph neural networks, and transformers.The emphasis throughout is on powerful methods that have been shown to be of proven value. Cutting-edge and authoritative,Artificial Neural Networks, Fourth Editionprovides up-to-date information on the practical use of AI in bioscience, which and should be valuable in the planning of new bioscience projects. 480 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition provides new and up-to-date methods to study RNA chaperonesin vitro and protocols for cell-based assays. Chapter guide readers through bacterial proteins, proteins from eukaryotic cells, complex interactions between RNA chaperones, and the folding and unfolding of proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, RNA Chaperones: Methods and Protocols, Second Edition aims to be comprehensive guide for researchers in the field 336 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This detailed new edition complements the previous edition with updates and new chemistry, concepts, and applications in the study of peptide nucleic acids (PNAs). The focus is on in vivo properties, behavior, and innovative applications of PNA, while maintaining contributions on both chemistry and nucleic acid recognition. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, Peptide Nucleic Acids: Methods and Protocols, Fourth Edition aims to inspire discovery and pursuit of new exciting avenues in the broad area of artificial DNA. 360 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This second edition volume expands on the previous edition with a discussion of the latest methods used to explore collagen biology from molecular synthesis and folding to biomechanical analysis and tissue engineering applications. The chapters in this book are organized into four parts: Part One introduces strategies for manipulating collagen at the molecular level, including gene targeting, mutagenesis, and functional assays. Part Two focuses on cellular and biochemical aspects of collagen biology, featuring protocols to study the effects of hypoxia, assess triple helix stability, and investigate ECM-rich environments using proteomics and mass spectrometry. Part Three covers structural and imaging techniques such as atomic force microscopy and advanced visualization of collagen suprastructures, and Part Four looks at translational and biomedical research, providing protocols for constructing 3D ECM scaffolds, engineering collagen-based biomaterials, and modeling tumor microenvironments. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Collagen: Methods and Protocols, Second Edition is a valuable resource for researchers in cell biology, biochemistry, tissue engineering, and translational medicine, and will support the development of novel strategies to explore and manipulate the power of collagen.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 292 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides a comprehensive overview of experimental models of neuropathic pain and state-of-the-art strategies for the assessment of pain and its associated behavioral and functional outcomes. The book is organized into two complementary parts. Part One focuses on experimental models that, despite their diverse etiologies, converge on a shared neuropathic substrate, ranging from the spared nerve injury (SNI) and FRICT-ION (Foramen Rotundum Inflammatory Constriction Trigeminal InfraOrbital Nerve) models to central traumatic neuropathies and systemic conditions such as diabetic and toxin-induced neuropathies. Part Two is dedicated to pain-related manifestations, with particular emphasis on endophenotypic outcomes, ultrasonic vocalizations, burrowing behavior, anxiety- and depressive-like phenotypes and executive function. In keeping with the tradition of the Neuromethods series, chapters include the kind of detail and key advice from the specialists needed to get successful results in the researchers' laboratories.Thorough and practical, Translational Research Methods for Neuropathic Pain is a valuable resource for all researchers looking to learn more about this important and developing field.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 384 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This second edition details updated methods and protocols for detection and quantification of bacteria, viruses and protozoan in different food matrices (fresh or processed) and freshwater. Chapters introduce the topic, materials, methods, a step-by-step description, figures, graphs or tables. Tips to avoid mistakes that compromise the analytical technique performance and reduce the working time, and supplies. At the end of each chapter, the key references are listed. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols.Authoritative and cutting-edge, Detection and Quantification of Bacteria, Yeast, Viruses, and Protozoan in Foods and Freshwater, Second Edition aims to provide basic and comprehensive information about protocols and methods for detection, quantification and characterization of microorganisms in foods, without disregarding the limitations or details in each specific procedure.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, Heidelberg 220 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume details encapsulation protocols with a focus on the combination of raw materials to enable an initial laboratory production of classic particles. Chapters guide readers through modification to produce porous starches, hydrogels, dry and insoluble particles, Layer-by-Layer, fluidized bed, and encapsulation methods and the general properties of the particles obtained. Written in the format of the Methods and Protocols in Food Science series, chapters list necessary materials and methods for readily reproducible protocols and contain notes on how to avoid and solve typical problems. Authoritative and cutting-edge, Biopolymers: Encapsulation Methods provides well-established protocols used by both academics and industrials.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 176 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed volume examines techniques for better understanding mammalian preimplantation embryo development, the development and contribution of gametes, and how to manipulate such reproductive cells in the laboratory. Written by experts in their field, the book covers gamete preparation, in vitro embryo culture and cryopreservation, physiological and molecular methods for embryo assessment, and emerging methods for modeling key developmental processes encompassing gamete and embryo manipulation through implantation. As part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and practical, The Preimplantation Embryo: Methods and Protocols serves as a comprehensive and practical toolbox and will be of immense value to scientists working on the fascinating and dynamic preimplantation embryo and the gametes from which it originates.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 516 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume describes the latest developments in using Artificial Intelligence (AI) and machine learning in the field of genomics. The chapters in this book cover a variety of topics such as ways to derive the biomarker and measure biological and pathological processes from transcriptomic data sets; techniques to infer the function of epigenetics using network-based methodology; a look at how CellOracle can figure out which gene-gene interaction is important; how to find a machine learning approach to figure out how microRNA affects the cardiovascular events; protocols on ways to find how AI/ML approaches can attack somatic variant detection in normal human tissue; and a description on how gene embeddings are powerful tools for predicting unknown functions of genes and drugs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and comprehensive, AI/ML-Driven Gene Analysis: Methods and Protocols is a valuable tool for researchers interested in learning more about how cutting-edge methodology for AI/ML is applied to genomics.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 280 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides a comprehensive guide of cutting-edge technologies applied in the discovery of metabolic gene clusters across different domains of life. Chapter guide readers through cluster identification, characterization, evolutionary analyses, synthetic assembly, pathway re-constitution, cluster regulation and activation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, Metabolic Gene Clusters: Methods and Protocols aims to spur new discoveries in the field of metabolic gene clusters and bring different areas of research closer together.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, Heidelberg 232 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume details methods ranging from environmental isolation, small-scale to large-scale cell cultivation, genome sequencing, genome editing, and 'omics' studies. Chapters provide reliable and practical resources that strengthen the collective toolkit of the U. maydis community and fosters further discoveries in fungal biology, plant pathology, applied microbiology and beyond. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, Ustilago maydis: Methods and Protocols aims to be comprehensive guide for researchers in the fieldSpringer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 536 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This second edition provides new and up-to-date methods to study RNA chaperones in vitro and protocols for cell-based assays. Chapter guide readers through bacterial proteins, proteins from eukaryotic cells, complex interactions between RNA chaperones, and the folding and unfolding of proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, RNA Chaperones: Methods and Protocols, Second Edition aims to be comprehensive guide for researchers in the fieldSpringer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 336 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides comprehensive methods and protocols to detect and trace RNAs in biochemistry, molecular, cell biology, genetics, genomics of RNA biology. Chapters detail RNA labeling, RNA biology of mammalian cells, and methods on model organisms; including Zebrafish, Drosophila, C. elegans, budding yeast as well as prokaryotes including E. coli. Written for the highly successful Methods in Molecular Biology series, chapters feature introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, RNA Labeling: Methods and Protocols serves as a vital resource for researchers working in RNA labeling.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 272 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This detailed new edition presents current techniques for researching arbuscular mycorrhizal (AM) fungi. With an updated and expanded collection of protocols, this book explores molecular quantification, high¿resolution imaging, metabolite profiling, transcriptomic and proteomic analyses, functional genomics, and advanced cultivation systems. Methods for asymbiotic growth and the study of functional traits of AM fungi and techniques to describe microbial communities, including viruses, associated with AM fungal hyphae are also included. Written for the highly successful Methods in Molecular Biology series, chapters feature introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, Arbuscular Mycorrhizal Fungi: Methods and Protocols, Second Edition serves as a vital resource for researchers working in different areas of AM fungal biology.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 296 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This sixth edition volume expands on the previous editions with a discussion of the latest methods used to detect RNA or DNA species in situ, including both short and long RNAs, and coding and non-coding RNAs. The chapters in this book are organized into five parts: RNA detection techniques; RNA and protein co-detection; 3D and wholemount ISH; spatial transcriptomics approaches; and image analysis and quantification. Some of the topics covered in this volume are detection of viral pathogens using RNAscope; detection of therapeutic antisense oligonucleotides using miRNAscope assays; RNAscope HiPlex in tissue sections and wholemounts; spatial transcriptomics platforms with accompanying data processing; and various image analysis platforms for downstream quantitative assessment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, In Situ Hybridization Protocols, Sixth Edition brings together a collection of protocols, along with practical notes and recommendations, and offers researchers a comprehensive introduction to the current leading edge of in situ hybridization.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 448 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume bridges the gap between foundational principles and cutting-edge applications used in the evolving field of intrathecal drug delivery. The chapters in this book are organized into four parts: Part One explored the history of neuraxial therapy and the fundamental principles of neuroanatomy, cerebrospinal fluid physiology, and pharmacokinetics. Part Two looks at the transitions from theory to practice, detailing the established clinical applications and surgical techniques for chronic pain, spasticity, CNS infections, and oncology. Parts Three and Four delve into the application of novel therapeutics for neurodegenerative and leptomeningeal diseases, the design of advanced formulations such as nanoemulsions, and an examination of the challenges and emerging solutions that will define the next generation of intrathecal drug delivery systems. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Cutting-edge and comprehensive, Intrathecal Drug Delivery is a valuable tool for researchers at all levels, from medical and graduate students to residents and postdoctoral fellows, who are interesting in learning more about this developing and important field.Springer Nature Customer Service Center GmbH, Europaplatz 3,69115 Heidelberg, Germany, 69115 Heidelberg 272 pp. Englisch.…