Rsc publishing nov 2011 (17 risultati)

Buch. Condizione: Neu. Neuware - The ultimate aim of IUPAC nomenclature is to provide unequivocal and comprehensible names for all kinds of chemical structures. This requires a rational basis from which comprehensible names can be developed. Written by leading world authorities this second edition of Principles of Chemical Nomenclature outlines IUPAC recommendations for application in the principle branches of chemistry: organic, inorganic, organometallic, and polymer. It also includes some basic biochemical nomenclature. The book clearly explains the fundamental principles of nomenclature methods and enables the reader to apply them accurately and with confidence. New developments are described and additional nomenclature systems used in specific industries are introduced. The book is replete with examples for guidance and there are extensive tables to direct the reader to information quickly. Aimed at chemistry teachers and students at all levels, it advises on the best presentation of formulae and chemical graphics. Although rather advanced for school pupils, their teachers will find it useful.…

Taschenbuch. Condizione: Neu. Neuware - One of the most important parts of British heavy industry today is our railway system. Its constant appearances in news bulletins, its enormous appeal to fans or 'enthusiasts', its permanent role in the lives of most of us, and its economic significance today, all underline its importance. Railway historians and enthusiasts will be surprised to learn that chemists played an important part in the development of the railway industry in Britain. Chemists themselves are well aware of the many and wide-ranging applications of their discipline, but the fact that their predecessors were involved in the technological development of railways will come as a surprise to many. This book is the first detailed study of this important interaction and covers the crucial role that chemistry played in the development of the British railway industry from its beginnings in the early 19th century up to the grouping of the railways of 1923 into GWR, SR, LNER, and LMSR.The book describes the vital relationship between chemistry and the railway industry, all very recently discovered. It shows that the railway system would simply have not been possible without chemical inputs, chiefly but by no means entirely analytical. This discovery about a huge revenue-earning industry in Britain came from rare documents recently unearthed and other archival material and the book contains many rare illustrations and vast amounts of previously unpublished material. For the historian, it is a classic case of where history of science and history of technology converge. A great many engineers contributed to the enormous technological development which occurred in the railway industry between 1830 and 1923, but working alongside the engineers were the chemists, and in certain critical areas their contribution to this development was vital. It is a contribution which up until now has not been adequately recognised, and this book puts the record straight.The book has an unusually wide appeal, being of interest to practising chemists, those interested in the history of chemistry and its role in society, historians of science and technology, mechanical engineers, and not least railway enthusiasts and railway historians. The chemist will be justly proud of the extreme importance of the subject for industry and the railway enthusiast will gain a wholly new picture of the development of the industry in Britain. …

Taschenbuch. Condizione: Neu. Neuware - The sun provides solar energy which is clean and environmentally friendly and can be directly used to produce thermal as well as electrical power. It is also directly the main source of all renewable energy sources discussed in this book. Due to global industrialization and the sharp increase of CO2, there is an increasing need to develop less polluting renewable energy sources for our long term survival and to balance the ecological system. This book is a unique and complete book covering renewable energy resources and contains a detailed analysis of energy and exergy, CO2 mitigation, and CO2 credit of various renewable energy sources. It is an ideal reference for teaching renewable energy to engineering and science students, as well as a reference book for scientists and professionals doing self study on the subject.…

Taschenbuch. Condizione: Neu. Neuware - This book is a practical, easy to use guide for readers with limited experience of molecular modelling. It will provide students at the undergraduate and early postgraduate chemistry level with a similar entry to modelling. The needs of independent readers are catered for by the inclusion of instructions for acquiring and setting up a suitable computer. Unlike many other textbooks in this field, the authors avoid extensive discussion around complex mathematical foundations behind the methods, choosing instead to provide the reader with the choice of methods themselves. To further these aims of the book, compact discs are included that provide a comprehensive suite of modelling software and datasets. The continuing interest of the pharmaceutical industry in molecular modelling in early stage drug design is recognized by the inclusion of chapters Medicinal Chemistry and Drug Discovery. There is a chapter on modelling of the solid state, a subject that is also of importance for pharma, where problems due to polymorphism in the crystalline forms of drugs are often encountered in the later design stages.…

Buch. Condizione: Neu. Neuware - The proceedings of the World Conference on 'New developments in Acacia Gums Research and Products' demonstrating the latest frontiers in gum Arabic production, identification, classification and production.

Buch. Condizione: Neu. Neuware - This book contains a selection of papers discussing the state-of-the-art research in particulate materials science that were presented at the UK-China Particle Technology Forum III held at Birmingham, UK in 2011.

Buch. Condizione: Neu. Neuware - Immobilization of chiral catalysts is an important tool for improving overall efficiency of catalytic processes. However, heterogeneous catalysts often suffer from decreased activities and supported but still homogeneous catalysts can help overcome this issue. This book covers the most important concepts of homogeneous supported catalysis with an emphasis on enantioselective processes. It describes the state-of-the-art and latest developments in each area whilst critically evaluating the strengths and weaknesses of this important method. The book encompasses ionically-tagged catalysts, supported organocatalysts, supported ionic liquid phases, catalysis using soluble polymers, catalytic dendrimers, fluorous catalysts, water soluble catalysts and non-covalent immobilization methods. Potential developments and ideas for the future are also highlighted. There is a growing demand for effective and recyclable catalysts so this book, covering all the important methods in the field of supported homogeneous catalysis, will appeal to many researchers in academia and industry.…

Buch. Condizione: Neu. Neuware - In Europe the main oil-rich crops are Sunflower, Rapeseed and Olive which are grown primarily for food. The book discusses how to convert this whole crop into energy (fuels, power and heat), food and bioproducts (chemicals and/or materials), whilst making optimal uses of the side streams generated during farming/harvesting, primary processing (oil extraction and refining) and secondary processing (transesterification). This makes the process more economically competitive and improves the business margin for oil or biodiesel manufacturers. The book is of interest to the EU farming industry as the processes identified will help them with their businesses. Academia will also be interested for potential research areas in fields such as chemistry, biology, materials, engineering, economics and policy studies.…

Buch. Condizione: Neu. Neuware - In recent years, several new concepts have emerged in the field of stratospheric ozone depletion, creating a need for a concise in-depth publication covering the ozone-climate issue. This monograph fills that void in the literature and gives detailed treatment of recent advances in the field of stratospheric ozone depletion. It puts particular emphasis on the coupling between changes in the ozone layer and atmospheric change caused by a changing climate. The book, written by leading experts in the field, brings the reader the most recent research in this area and fills the gap between advanced textbooks and assessments.…

Buch. Condizione: Neu. Neuware - There are about 8 million deaths each year from neglected tropical diseases (NTDs) in the underdeveloped world, whilst drug discovery focus and practice is only recently taking on greater urgency and embracing the latest technologies. This unique book is a state of the art review of drug discovery in respect of NTDs and highlights best practice to guide ongoing drug discovery effort and also to raise debate and awareness in areas that remain highly neglected. All the major diseases such as malaria, trypanosomatids and TB are covered, with a review of each disease and established compounds, new mechanistic classes and new horizons. Each chapter highlights the key science that has led to breakthroughs, with detailed assessment of the key medicinal chemistry involved, and critical appraisal of new emerging approaches.…

Buch. Condizione: Neu. Neuware - This unique book describes newly discovered proteolytic enzymes and their biological function. In many cases, these enzymes are targets for new drug discovery in order to provide new therapeutic approaches to control human diseases and/or metabolic conditions. The chapters in this book will help other investigators to pursue drug discovery by detailing methods of production and assay of the enzymes. In addition, the latest structural studies that are described in the book will permit rapid advances in drug design. The most important elements of this book are the state-of-the-art, detailed descriptions of the properties of the proteolytic enzymes. The chapters in the book, written by leading experts in the field, collect the best work on the topics with complete bibliographies for each target enzyme. The illustrations are highly informative to aid and facilitate a new design of inhibitors that can be developed as drug candidates. Key chapters include those by Mark Gorrell and Catherine Abbott, both describing dipeptidyl peptidases, which have been implicated in a number of metabolic conditions including diabetes. The chapters are written from two very different perspectives, thus enriching the literature in this area. In addition, the chapter by Sheena McGowan focuses on aminopeptidases from the malaria parasite, Plasmodium falciparum, and the chapter by Ben Dunn deals with the aspartic peptidases from the same organism.…

Buch. Condizione: Neu. Neuware - Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. Aberrations in their function or metabolism play a role in diseases such as cancer and parasitic infection. A number of validated drug targets have been identified, including enzymes in the polyamine biosynthetic and catabolic pathways and the S-adenosylmethionine synthetic and salvage pathways. Polyamine Drug Discovery is the first comprehensive volume to cover all aspects of the design and development of potential therapeutics targeting polyamine metabolism. The book details research progress from 1975 to the present date and discusses the design and use of polyamine metabolism inhibitors as therapeutic agents. Various polyamine-containing drugs are described that can be used in chemotherapy, and as treatments for infections including trypanosomiasis, leishmaniasis and malaria. Finally, the roles of polyamine analogues in chemoprevention, polyamine-containing vectors for gene delivery, and the design of polyamine-based epigenetic modulators are detailed. Each chapter addresses a different aspect of polyamine drug discovery and all are written by medicinal and biological chemists with particular expertise in developing agents that modulate polyamine metabolism or function. The book will increase the visibility of polyamine drug discovery among pharmaceutical researchers and provide a valuable reference for everyone working in the field. …

Buch. Condizione: Neu. Neuware - Today, we are surrounded by a multitude of different chemicals that are essential components of our everyday life. As a consequence, there are various hazardous substances like dioxins, phthalates and flame-retardants circulating in the environment. These have an impact on ecosystems, wildlife and possibly human health. In recent years, the phenomenon called endocrine disruption has raised considerable concern. This book discusses the scientific basis of this issue using epidemiological and experimental in vitro and in vivo data about chemicals targeting the hormonal systems. It also provides an up-to-date review of international initiatives (including high-throughput screening, use of model organisms and in silico applications) aiming to screen, detect and functionally test these chemicals. The authors are highly experienced academics and acknowledged experts with both multidisciplinary and international expertise. The book provides an up-to-date, in-depth review of the current field of food safety research describing many of the 'hot topics' currently debated. Recent media attention concerning, for example, dioxins in meat and bisphenol A in baby bottles has created a growing interest in food safety-related issues from both consumers and authorities. In addition, European legislation REACH, which requires industry to extensively test chemicals, has led to new initiatives within this area. This book presents a comprehensive overview of the recent international initiatives formed to meet the challenges of environmental pollutants in our food.…

Buch. Condizione: Neu. Neuware - Computer-Assisted Structure Elucidation (CASE) systems are a combination of software algorithms and tools to support and enable chemists and spectroscopists engaged in the process of molecular structure elucidation via the analysis of spectroscopic data. These expert systems dramatically reduce the time associated with structure elucidation and improve the reliability of the results. Contemporary Computer-Assisted Approaches to Molecular Structure Elucidation describes the principles on which these expert systems for spectroscopic structure elucidation are based and concisely explains the algorithmic concepts behind the programs. The authors use their own personal experiences in the development of the Structure Elucidator (StrucEluc) CASE software system to discuss the present state-of-the-art in computer-assisted structure elucidation.…

Buch. Condizione: Neu. Neuware - This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion. Each chapter includes a brief review of the topic showing the historical development of quantitative approaches, a survey/summary of the current state-of-the-art, a selection of well chosen examples with some worked through and an appreciation of what problems remain to be overcome as well as an indication of how the field may develop.…

Buch. Condizione: Neu. Neuware - The discovery of caged carbon structures, in 1985, established a whole new field of carbon chemistry. Unlike graphite and diamond, these structures known as fullerenes are finite in structure and are relevant to a wide variety of fields including supramolecular assemblies, nanostructures, optoelectronic devices and a whole range of biological activities. Fullerenes: Principles and Applications discusses all aspects of this exciting field. Sections include: the basic principles for the chemical reactivity of fullerenes, electrochemistry, light induced processes, fullerenes for material sciences, fullerenes and solar cells, biological applications and multifunctional carbon nanotube materials. Written by leading experts in the field the book summarises the basic principles of fullerene chemistry but also highlights some of the most remarkable advances that have occurred in recent years. Fullerenes: Principles and Applications will appeal to researchers in both academia and industry.…

Buch. Condizione: Neu. Neuware - Toxicology continues to be a major cause of product attrition; in addition the implementation of REACH is having an impact on our need to continually improve our capabilities to predict potential safety concerns earlier. This unique book provides a comprehensive review and discussion on the status of predictive toxicology and its application. This is a critical hot topic and an area of continuing importance and the book is timely in providing a leading and expert treatise. Chapters cover the current approaches in predictive toxicology including in silico, in vitro and in vivo. In addition, examples of how these approaches can be integrated to improve the safety assessment to humans are covered. There is also discussion of current approaches for biomarker identification and application (eg omics approaches).…