Springer berlin heidelberg jul 2007 (111 risultati)

Buch. Condizione: Neu. Neuware -Themodernbillion-dollardrug-discoveryprocessstronglyreliesonbothhi- throughput synthesis and screening methods. Whereas the latter is based on molecular biological methods, the ef cient and reliable generation of c- pound collections often makes use of combinatorial chemistry. Discovered in the 1980s, this methodology was explored extensively in the 1990s by groups in academia and in industry. Without any doubt, combinatorial chemistry changed the whole drug-discovery process and found many applications in cropscience and the material sciences. However, since its implementation, solution- and solid-phase techniques have been competing with each other, and although many companies started theircombinatorialchemistryprogramwithsolid-phasetechniques,soluti- phase combinatorial methods have taken over and now account for appro- mately 25% of all combinatorial efforts. The syntheses of complex, non-polymeric structures, discovered in the 1960s by the late Bruce Merri eld, was largely ignored in the context of solid supports, mainly due to the fact that appropriate synthesis techniques were not available. Since solid-phase chemical methodology strongly differs from traditional solution-phase chemistry, two chapters deal with this topic. The Bräse group (Jung, Wiehn, Bräse) gives an overview of multifunctional linkers, which can beusedforthegenerationofdiversity-orientedcollections,simplybycleavage fromresins. Still in its infancy, solid-phase reactions employ simple amide chemistry in most cases due to their high-yielding, reliable protocols. Ljungdahl, Br- eld, and Kann address solid-phase organometallic chemistry, which is now one ofthe great challenges in reliable solid-phase organicsynthesis. 376 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a thorough and comprehensive treatment of irregular wavelet frames. It introduces and employs a new notion of affine density as a highly effective tool for examining the geometry of sequences of time-scale indices. Coverage includes non-existence of irregular co-affine frames, the Nyquist phenomenon for wavelet systems, and approximation properties of irregular wavelet frames. 156 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Eigenvectors of graph Laplacians have not, to date, been the subject of expository articles and thus they may seem a surprising topic for a book. The authors propose two motivations for this new LNM volume: (1) There are fascinating subtle differences between the properties of solutions of Schrödinger equations on manifolds on the one hand, and their discrete analogs on graphs. (2) 'Geometric' properties of (cost) functions defined on the vertex sets of graphs are of practical interest for heuristic optimization algorithms. The observation that the cost functions of quite a few of the well-studied combinatorial optimization problems are eigenvectors of associated graph Laplacians has prompted the investigation of such eigenvectors.The volume investigates the structure of eigenvectors and looks at the number of their sign graphs ('nodal domains'), Perron components, graphs with extremal properties with respect to eigenvectors. The Rayleigh quotient and rearrangement of graphs form the main methodology. 120 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book discusses the effects of emerging technologies on surgeons and surgical practice. The book opens with an overview of disruptive technologies, and their economic, scientific, ethical and social implications. Next comes a section describing how the Internet, virtual reality and simulation technology will change training and education. A section on Robotics covers computer-guided surgery, robotics and endoluminal therapies. Innovations in surgical instruments, including MEMS and Nanotechnology are outlined, as well. Next, the book reviews tissue engineering and artificial organs, genetic engineering, stem cells, emerging transplantation technologies and the brain-machine interface. A concluding section discusses ways of adapting to future technologies. 168 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With ever more commerce being done online, and the complexity of the world wide web growing every day, engineering the web has become a topic of growing contemporary relevance. This book constitutes the refereed proceedings of the 7th International Conference on Web Engineering, held in Como, Italy in July 2007. The 26 revised full papers and 13 revised short papers presented together with 9 demonstration papers, 4 industrial papers, and 4 papers of the doctoral symposium, were carefully reviewed and selected from 172 submissions. 596 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Statistical analysis of stock markets and foreign exchange markets has demonstrated the intermittent nature of economic time series. A nonlinear model of business cycles is able to simulate intermittency arising from order-chaos and chaos-chaos transitions. This monograph introduces new concepts of unstable periodic orbits and chaotic saddles, which are unstable structures embedded in a chaotic attractor and responsible for economic intermittency. 116 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book explains key financial concepts, mathematical tools and theories of mathematical finance. It is organized in four parts. The first brings together a number of results from discrete-time models. The second develops stochastic continuous-time models for the valuation of financial assets (the Black-Scholes formula and its extensions), for optimal portfolio and consumption choice, and for obtaining the yield curve and pricing interest rate products. The third part recalls some concepts and results of equilibrium theory and applies this in financial markets. The last part tackles market incompleteness and the valuation of exotic options. 340 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the thoroughly refereed and extended post-proceedings of the 11th Annual ERCIM International Workshop on Constraint Solving and Constraint Logic Programming, CSCLP 2006, held in Caparica, Portugal in June 2006. The papers are organized in topical sections on global constraints, search and heuristics, language and implementation issues, and modeling. 196 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications. 144 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Making networks and services dependable is, of course, extremely high on the priority list of any network manager and that makes this book a vital tool in the armory of any researcher or professional in the field. These are carefully revised texts of selected lectures given at the 13th EUNICE Open European Summer School as well as the conjoint IFIP workshop, held in the Netherlands in July 2007. The papers are organized in topical sections on middleware and supportive services and context-awareness, among other topics. 168 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The papers in this volume represent the proceedings of the 7th Industrial Conference on Data Mining. They are organized into topical sections on aspects of classification and prediction, clustering, web mining, data mining in medicine, applications of data mining, time series and frequent pattern mining, and association rule mining. Readers gain new insights into theories underlying data mining and discover state-of-the-technology applications. 368 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The refereed proceedings of the 7th International Conference on Case-Based Reasoning are presented in this volume. Fifteen full research papers and eighteen poster papers are presented along with three invited talks. The papers address all aspects of case-based reasoning, featuring original theoretical research, applied research, and applications with practical, social, environmental, and economic significance. 552 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -No fewer than 55 revised full papers are presented in this volume, all given at the 4th International Conference on Autonomic and Trusted Computing, held in Hong Kong, China in July 2007. The papers, presented together with one keynote lecture, were carefully reviewed and selected from 223 submissions. The papers are organized in topical sections on, among others, cryptography and signatures, autonomic computing and services, and secure and trusted computing. 592 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Researchers and professionals in the appropriate subject areas will find this book an essential update on where research has got to in what is, after all, a hugely important area. It constitutes the refereed proceedings of the 7th International Workshop on Systems, Architectures, Modeling, and Simulation, held in Samos, Greece, in July 2007. The 44 revised full papers presented together with 2 keynote talks were thoroughly reviewed and selected from 116 submissions 488 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Decision modeling is a key area in the developing field of AI, and this timely work connects researchers and professionals with the very latest research. It constitutes the refereed proceedings of the 4th International Conference on Modeling Decisions for Artificial Intelligence, held in Kitakyushu, Japan, in August 2007. The 42 revised full papers presented together with 4 invited lectures are devoted to theory and tools, as well as applications. 516 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A veritable one-stop-shop for anyone looking to get up to speed on what is going down in the field of automated deduction right now. This book contains the refereed proceedings of the 21st International Conference on Automated Deduction, CADE-21, held in Bremen, Germany, in July 2007. The 28 revised full papers and 6 system descriptions presented were selected from 64 submissions. All current aspects of automated deduction are addressed, ranging from theoretical and methodological issues to presentation and evaluation of theorem provers and logical reasoning systems. 536 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the thoroughly refereed post-proceedings of the International Workshop on Statistical Network Analysis: Models, Issues, and New Directions held in Pittsburgh, PA, USA in June 2006 as associated event of the 23rd International Conference on Machine Learning, ICML 2006. It covers probabilistic methods for network analysis, paying special attention to model design and computational issues of learning and inference. 208 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -OnbehalfoftheProgramCommittee,itisourpleasuretopresenttoyouthep- ceedings of the 4th GI International Conference on Detection of Intrusions and Malware, and Vulnerability Assessment (DIMVA). Each year DIMVA brings - gether internationalexperts from academia,industry andgovernmentto present and discuss novel security research. DIMVA is organized by the special interest group Security Intrusion Detection and Response of the German Informatics Society (GI). The DIMVA 2007 Program Committee received 57 submissions from 20 d- ferentcountries. Allsubmissions werecarefullyreviewedbyProgramCommittee members and external experts according to the criteria of scienti c novelty, - portance to the eld and technical quality. The nal selection took place at a Program Committee meeting held on March 31, 2007, at Universit` a Campus Bio-Medico di Roma, Italy. Twelve full papers and two extended abstracts were selectedforpresentationatthe conferenceandpublicationin theconferencep- ceedings. The conference took place during July 12 13, 2007, at the University of Applied Sciences and Arts Lucerne (HTA Lucerne) in Switzerland. The p- gram featured both theoretical and practical research results grouped into ve sessions. ThekeynotespeechwasgivenbyVern Paxson,InternationalComputer Science Institute and Lawrence Berkeley National Laboratory. Another invited talk was presented by Marcelo Masera, InstitutefortheProtection and Security of the Citizen. Peter Trachsel, Deputy Head of the Federal Strategic Unit for IT in Switzerland, gave a speech during the conference dinner. The conference programfurther included a rump sessionorganizedby Sven Dietrich of Carnegie Mellon University; and it was complemented by the third instance of the Eu- pean capture-the- ag contest CIPHER, organized by Lexi Pimenidis of RWTH Aachen. 264 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the concept of cognition in a clear, lucid and highly comprehensive style. It provides an in-depth analysis of mathematical models and algorithms, and demonstrates their application with real life experiments. 308 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the refereed proceedings of the 19th International Conference on Computer Aided Verification. Thirty-three state-of-the-technology papers are presented, together with fourteen tool papers, three invited papers, and four invited tutorials. All the current issues in computer aided verification and model checking-from foundational and methodological issues to the evaluation of major tools and systems-are addressed. 584 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There is a world beyond Turing, as more and more computer researchers are demonstrating, but where would you find out about the current leading edge in unconventional computation Here, in this fascinating work that is the refereed proceedings of the 6th International Conference on Unconventional Computation, held in Kingston, Canada, in August 2007. The 17 revised full papers presented together with 4 invited papers were carefully reviewed and selected for inclusion in the book. All current aspects of unconventional computation are addressed. 256 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the thoroughly refereed post-proceedings of the 16th International Conference on Inductive Logic Programming, ILP 2006, held in Santiago de Compostela, Spain, in August 2006. The papers address all current topics in inductive logic programming, ranging from theoretical and methodological issues to advanced applications. 476 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Running to almost 400 pages, and featuring more than 40 papers, this work on combinatorial optimization and applications will be seen as an important addition to the literature. It constitutes the refereed proceedings of the first International Conference on Combinatorial Optimization and Applications, COCOA 2007, held in Xi'an, China in August of that year. The 29 revised full papers presented together with 8 invited papers and 2 invited presentations were carefully reviewed and selected from 114 submissions and cover both theoretical issues and practical applications. 404 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Who could have predicted that the S eminaire de Probabilit es would reach the age of 40 This long life is rst due to the vitality of the French probabil- tic school, for which the S eminaire remains one of the most speci c media of exchange. Another factor is the amount of enthusiasm, energy and time invested year after year by the R edacteurs: Michel Ledoux dedicated himself tothistaskuptoVolumeXXXVIII,andMarcYormadehisnameinseparable from the S eminaire by devoting himself to it during a quarter of a century. Browsing among the past volumes can only give a faint glimpse of how much is owed to them; keeping up with the standard they have set is a challenge to the new R edaction. In a changing world where the status of paper and ink is questioned and where, alas, pressure for publishing is increasing, in particular among young mathematicians, we shall try and keep the same direction. Although most contributions are anonymously refereed, the S eminaire is not a mathema- cal journal; our rst criterion is not mathematical depth, but usefulness to the French and international probabilistic community. We do not insist that everything published in these volumes should have reached its nal form or be original, and acceptance-rejection may not be decided on purely scienti c grounds. 504 pp. Englisch, Französisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Based on more than 10 years of teaching experience, Blanken and his coeditors have assembled all the topics that should be covered in advanced undergraduate or graduate courses on multimedia retrieval and multimedia databases. The single chapters of this textbook explain the general architecture of multimedia information retrieval systems and cover various metadata languages such as Dublin Core, RDF, or MPEG. The authors emphasize high-level features and show how these are used in mathematical models to support the retrieval process. For each chapter, there's detail on further reading, and additional exercises and teaching material is available online. 392 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this comprehensive introduction to software measurement, Ebert and Dumke detail knowledge and experiences about the subject in an easily understood, hands-on presentation. The book describes software measurement in theory and practice as well as provides guidance to all relevant measurement tools and online references. In addition, it presents hands-on experience from industry leaders and provides many examples and case studies from Global 100 companies. Besides the many practical hints and checklists, readers will also appreciate the large reference list, which includes links to metrics communities where project experiences are shared. 576 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a subject that is as hot as a snake in a wagon rut, offering as it does huge potentiality in the field of computer programming. That's why this book, which constitutes the refereed proceedings of the 7th International Symposium on Abstraction, Reformulation, and Approximation, held in Whistler, Canada, in July 2007, will undoubtedly prove so popular among researchers and professionals in relevant fields. 26 revised full papers are presented, together with the abstracts of 3 invited papers and 13 research summaries. 432 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The refereed proceedings of the 12th Asia-Pacific Computer Systems Architecture Conference are presented in this volume. Twenty-six full papers are presented together with two keynote and eight invited lectures. Collectively, they represent some of the most important developments in computer systems architecture. The papers emphasize hardware and software techniques for state-of-the-art, multi-core and multi-threaded architectures. 416 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The nature and essence of Dark Matter and Dark Energy have become the central issue in modern cosmology over the past years. This extensive volume, an outgrowth of a topical and tutorial summer school, has been set up with the aim of constituting an advanced-level, multi-authored textbook which meets the needs of both postgraduate students and young researchers in the fields of modern cosmology and astrophysics. 452 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Researchers and professionals in the relevant fields will find this book a must-read, as it defines the leading edge of current research into conceptual structures. It constitutes the refereed proceedings of the 15th International Conference on Conceptual Structures, held in Sheffield, UK in July 2007. With almost 50 papers contained in its 500 pages, it includes a special focus on the application of conceptual structures in business and technological settings and is organized into topical sections for ease of reference. 532 pp. Englisch.…