springer berlin springer international publishing springer jul 2014 (6 risultati)

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Martin Stein's thesis describes a novel methodology for natural product discovery. Due to its high degree of reproducibility, robustness and sensitivity, the technique can be utilized to detect even trace amounts of bioactive substances in heterogeneous matrices such as fermentation broths or crude organic extracts. This research is thus relevant for a large number of researchers working in natural product discovery. Applications of this novel NMR-based approach include suitable environmental triggers for the induction of biosynthetic machineries. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens. This thesis has led to a number of publications in high-impact journals. 71 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Positron Emission Tomography with Computed Tomography (PET/CT) is a nuclear medicine imaging modality using positron-emitting radiotracers and a combined PET and CT scanner in order to detect and localize high radiotracer signal abnormalities. Although PET has evolved into a diagnostic modality of prime importance in oncology (with the radiotracer (F18-FDG) it was originally envisioned to image and diagnose diseases of the brain and the heart. Lack or limited experience in PET may result in an erroneous interpretation of the findings in this sensitive imaging modality. The existence of various rare cancers has resulted in scanty if not a lack of knowledge about the usefulness of PET in these interesting albeit uncommon maladies. The author, drawing from more than ten years of experience as the chairman/director of the only PET Center in the Philippines, aims to present the most interesting cases he has encountered which may be educational to those beginning their practice or even helpful to veterans of the field whose scope of practice has been limited to the most common and reimbursable indications of an FDG-PET scan. 125 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This manual is a condensed and didactic 'how to' book, demonstrating surgical procedures in a step by step manner. It is fully comprehensive and highly illustrated (in colour, using mostly operative photographs), restricted solely to the surgical management of maxillofacial trauma, but includes most of the surfical approaches and methods of repair for all maxillofacial injuries. By including all surgical procedures (in trauma) this manual will make a useful and portable accompaniment to the Atlas of Operative Maxillofacial Trauma Surgery . It will be a good resource for all trainees, not only in maxillofacial surgery, but also in other related specialties. 170 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming. The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis is made on the emerging science of epigenetics as a potential explanation for how environmental events that occur during brief windows of development may exert effects that impact upon somatic cells through many rounds of mitosis for much of the life span of the subsequent organism. 189 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Theory of Dynamical Systems was first introduced by the great mathematician Henri Poincaré as a qualitative study of differential equations. For more than forty years, Jacob Palis has made outstanding contributions to this area of mathematics. In the 1970s, following in the wake of Stephen Smale, he became one of the major figures in developing the Theory of Hyperbolic Dynamics and Structural Stability.This volume presents a selection of Jacob Palis' mathematical contributions, starting with his PhD thesis and ending with papers on what is widely known as the Palis Conjecture. Most of the papers included in the present volume are inspired by the earlier work of Poincaré and, more recently, by Steve Smale among others. They aim at providing a description of the general structure of dynamical systems.Jacob Palis, whose work has been distinguished with numerous international prizes, is broadly recognized as the father of the Latin American School of Mathematics in Dynamical Systems and one of the most important scientific personalities on the continent. In 2010 he was awarded the Balzan Prize for his fundamental contributions in the Mathematical Theory of Dynamical Systems, which has been the basis for many applications in various scientific disciplines. 711 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book focuses on morphological and anatomical strategies developed by halophytes during evolution that allow them to survive in high-salt environments. These adaptive strategies refer to well integrated structural features, such as succulence, salt secretion (salt glands and vesicular hairs), aerenchyma, Kranz anatomy, bulliform cells, successive cambia, tracheoidioblasts and endodermis with pronounced Casparian strips. The authors present cross sections of the roots, stems and leaves of 62 halophyte species belonging to 18 families from different habitats and climates (temperate, Mediterranean). They also discuss the ecological, physiological and evolutionary aspects of the various adaptive structures in an integrative way. Beginning with the structural level, this book offers novel insights into the ecology of halophytes and opens new perspectives for the identification of salt-tolerant crop plants or halophytes that can be used for ecological purposes, such as bio-remediation and revegetation. 548 pp. Englisch.