springer chapman and hall crc feb 2012 (78 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -of McGill University of Montreal, Canada, who talks about artifi cial cells prepared from semipermeable microcapsules. Also illustrative of this method is a contribution on microencapsulated pesticides by C. B. Desavigny and E. E. Ivy of Pennwalt Corporation. Another method of polymerization in situ is micro encapsulation by vapor deposition, the subject of W. M. Jayne of Union Carbide Corporation. The more mechanical methods of microencapsulation are represented by two techniques, one involving a fluidized bed the other involving mainly a centrifugal method. The fluidized bed method is covered in a paper by H. Hall and T. M. Hinkes of the Wisconsin Alumini Research Foundation. The centrifugal and other related methods are treated by Mr. J. E. Goodwin and Mr. Sommerville of the Southwest Research Institute of San Antoni~ Texas. Dr. G. Baxter of Moore Business Forms, studied capsules made by mechanical methods as well as by chemical methods. Mr. Russell G. Arnold of the Bureau of Veteranary Medicine of the Food and Drug Administration draws our attention to the procedures to be used for securing approval of a new animal drug application for the marketing of microencapsulated products. And last but not least, we have a contribution by Mr. G. O. Fanger on 'Micro encapsulation a Brief History and Introduction, whose title speaks for itself. 192 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Fritz Haber Symposium on Methods of Laser Spectroscopy was held in Ein Bokek, Israel, on the shores of the Dead Sea, on December 16-20, 1985. The location is the lowest place on earth, 392 meters below sea level. It was hoped that 120 active laser scientists, so lowly trapped in such a place, with the nearest entertainment 100 km away, will have no choice but to discuss laser spectroscopy. On the average, the Dead Sea area receives 3-4 days of rain each year, and this year these days all occurred during the conference. This did not mean the cancellation of the hikes, although the trip to Massada was conducted in the rain. The unexpected rains also caused flash floods in the area, and Ein Bokek was completely cut-off on Thursday night. The archeologist scheduled to speak after dinner, and the belly dancer scheduled to appear afterwards, (~ould not arrive, resulting in the only serious deviation from the original plan. The scientific program consisted of invited talks and contributed posters. The emphasis in selection of invited speakers and topics was on the methods rather than specific molecular systems, and an attempt was made to allow ample time for discussion after each lecture. The same philosophy guided us in editing this book, and authors were requested to write manuscripts longer than usual for standard conference proceedings. 512 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The XXX Congress of the International Union of Physiological Sciences took place in Vancouver, Canada, in July 1986; and this Volume contains a selection of the Review Lectures which formed part of the Congress programme. They cover most of the areas of contemporary physiology and were presented by distinguished scientists from many parts of the world. An innovation at this Congress was the inclusion in the programme of a number of lectures devoted to historical subjects. These lectures attracted large audiences at the meetings, and three of them also appear in this book. Finally, the Plenary Lectures which formed part of the opening and closing ceremonies and which deal with some aspects of Canadian physiological history, find a place here as well. The Editors are grateful to all of the authors who provided the manuscripts which go to make up this book, and to John Donald for his invaluable assistance in the preparation of the final text; as well of course to all of the contributors whose participation made the Congress the success which it was. It is hoped that this Volume will provide a useful memento of the event. 516 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is devoted to the chemistry, immunology, molecular biology, and physiology of the human chorionic gonadotropin, heG. For this glycoprotein molecule the course from discovery to chemical deciphering covered about fifty years. It was in 1928 that Ascheim and Zondek reported that urine from pregnant women contains something that stimulates the ovaries of mice or rats. This provided the basis for the famous A-Z test for pregnancy and for the 'rabbit test' modification introduced by Friedman. As researchers sought to find more sensitive responses to heG, they used a wide variety of species including the South African aquatic toad, Xenopus Zaevis, the terrestrial toad of South America, Bufo arinarus, and the African weaver finch, EupZeetes afra. The weaver finch feather reaction was particularly noteworthy, for it disclosed a non-gonadal response to heG/LH. In retrospect, this may have been an important evolutionary clue to the realization that the designation of the hormone as a 'gonadotropin' may have been only partially descriptive of the molecule's physiological function--a concept that is gaining attention, as the papers in this 1980 volume divulge. 520 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There has been a significant surge of interest in the study of the physiology and biochemistry of plant host-parasite interactions in recent years, as evidenced by the number of research papers currently being published on the subject. The in creased interest is probably based on the evidence that effective management of many plant diseases is, for the most part, contingent upon a clear understanding of the nature of host-parasite interactions. This intensified research effort calls for a greater number of books, such as this one, designed to compile, synthesize, and evaluate widely scattered pieces of information on this subject. The study of host-parasite interactions concerns the struggle between plants and pathogens, which has been incessant throughout their coevolution. Such in teractions are often highly complex. Pathogens have developed sophisticated of fensive systems to parasitize plants, while plants have evolved diversified defen sive strategies to ward off potential pathogens. In certain cases, the outcome of a specific host-parasite interaction seems to depend upon the presence or efficacy of the plant's defense system. A plant may become diseased when a parasite manages to invade it, unhindered by preexisting defense systems and/or without eliciting the plant's induced resistance response(s). Absence of disease may re flect the inability of the invading pathogen to overcome the plant's defense sys tem(s). 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is intended to educate the primary health care provider about sexually transmitted and related diseases as they present in homosexually active men. But why a book discussing sexually transmitted diseases (STDs) in this population only Surely STDs are not limited to homosexual males. The relatively high rates of incidence of many of these diseases among homosexually active men, however, and the large number of associated diagnostic and treatment problems have necessitated the collection into one volume of the information that is par ticularly relevant to the primary health care of this population. A book dealing with current trends in the diagnosis and treatment of sexual diseases can, by nature of the task, be neither encyclopedic nor all-encompassing. In this volume, the choice of disease entities and the amount of material included on each are based on consideration of the amount of current information and the relative degree of uniqueness of a given problem in homosexual men, rather than the absolute frequency of the disease. There is, therefore, a considerable amount of material on hepatitis B and gonococcal infections, reflecting the recent explosion of research and clinical investigation in these two areas. In contrast, little is said about nonspecific urethritis, chancroid, and lymphogranuloma ve nereum. In the case of nonspecific urethritis, although it is extremely common in homosexual men, little progress has been made in diagnosis or therapy. 296 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The contents of this book reflect a symposium held in honor of Professor Herman Kalckar's seventy-fifth birthday. His impact on the history of biochemistry is reflected by the diversity of the contributions of his former students and friends. Speakers came from Asia, Europe, and the United States to discuss both procaryotes and eukaryotes. The unifying theme was the cell membrane, both its organization and its function. Ektobiology, a topic that has held the attention of Professor Kalckar for many years, was clearly defined as a central topic in biology. This subject deals with the key structure whereby the cell interacts with the outside world and which, in a sense, defines the boundary between what is the cell and what is not. Topics discussed include the biogenesis of membrane proteins, sugars and lipids, the role of membrane components in osmoregula tion, and mechanisms of nutrient transport. Of great interest is the system for surface recognition evolved in vertebrates, exemplified by the HLA system of man. Neoplasia causes changes in the cell membrane that may be of significant future potential in the diagnosis and treatment of malignancies as well as in the understanding of the process of transformation. The changes in glycosphingolipids and carbohydrate antigens in relation to oncogenesis are detailed. I should like to recognize Doctors Kurt J. Isselbacher, Phillips W. Robbins, Victor Ginsburg, and Hiroshi Nikaido for their ,assistance in organizing the symposium. Ms. Jean Brumbaugh deserves special thanks for putting this book together. 312 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Noncrystalline (NC) solids, as is well known, lack the long range order of crystals. Accordingly, they exhibit scattering, e.g., x-ray, electron, and neutron, but not the diffraction patterns characteristic of crystals. The intensity distributions from NC solids are usually transformed into radial distribution functions (RDF), but the interpretation of the RDF's is not unique. The lack of long-range order, and the non-uniqueness of the structural interpretation, have constituted the main obstacles to the usual solid state physics approach which has been so successful in dealing with crystals. As a corrolary, questions of local order and structure have frequently been de-emphasized. This monograph contains a collection of chapters many of which emphasize local-structure and chemical bonding as opposed to long-range order. Most of the chapters were chosen from talks given at the international symposium, 'Structure and Bonding in Noncrystalline Solids,' held in Reston, Virginia in May of 1983. Other chapters, however, were simply submitted independently of the Reston conference. Thus, this book is not a proceedings of that conference, nor was it ever intended to be. The chapters presented here range from theory of bonding and structure, to structurally oriented measurements of various kinds, e.g., ESR, Raman, to more applied chapters. Our goal was to produce a monograph that enhances understanding of the structures of NC solids. 460 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Considering the enormous progress achieved in some special areas of superconductivity during the last few years, it seemed worthwhile to discuss thoroughly a subject, which has encountered severe pro blems on the theoretical and the experimental side, namely the effects of the anisotropic electron and phonon properties of (single crystalline) materials on the characteristic features of the super conducting state. The fact that the majority of scientists actively engaged in this research field at present were brought together at the meeting, has led to an almost complete coverage of the pertinent topics in this volume. Six review papers discuss the development and the present state of theory and experiment concerning the anisotropies of the upper critical field and the magnetization as well as the flux line lattice and the superconducting energy gap. Furthermore, 18 papers present the most recent research on these properties and additional anisotropy effects associated with the intermediate state patterns or the specific heat. Concerning the magnetic properties, remarkable agreement between theory and experiment has been achieved; on the other hand, controversial views regarding the existence of anisotropy in the superconducting energy gap are presented. In both cases, how ever, theorists and experimentalists are still confronted with a number of open questions. It is the purpose of this book to draw the attention of scientists to these fascinating problems. Harald W. 324 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invaluable reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts. 516 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is addressed to all biologists seeking a review of the various transport processes of minerals and organic substances in plants from the level of cell organelles to the longer-distance movements in the largest trees. It is directed toward students having had some elementary physiol ogy, but the attempt has been made to provide information of interest on the frontiers of current research. Doing this comprehensively, we wished to consider all of the points of view that appeared to be important; on the other hand, space and time were limited. Therefore, the presentation had to strike an intermediate ground between the style of a textbook giving of selected problems and a comprehensive ref representative treatments erence book covering all ramifications. The reader will notice that the pendulum will swing more toward one and then to the other. We did not want to avoid, and we felt it was not appropriate to neglect completely our own special research interests, which led to some emphasis on certain SUbjects. The immediate origin ofthe book is the Heidelberger Taschenbuch 125 (HTB 125) Stojjtransport der Pflanzen by U. L. (1973), which in turn was preceded by an earlier work, Aktiver Transport: Kurzstreckentransport bei Pflanzen Protoplasmatologia vol. VIII17 b by U. L. (1969). At the Li verpool Workshop on Ion Transport in 1972 organized by W. Peter An derson, and while in a jovial and expansive mood, the authors agreed to produce an English version. 484 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the invited lectures presented in a symposium entitled 'Evolutionary strategies of parasitic insects and mites' at the national meeting of the Entomological Society of America in Minneapolis, Minnesota, 2-5 December, 1974. The intent was to bring together biologists who have worked on arthropods that are either plant or animal parasites in order to foster consideration of general aspects of the parasitic way of life. There seems to be a deficiency of ecological and evolutionary concepts relating to parasitism, in contrast to the burgeoning literature on predation, and it appeared that an amalgamation of studies on plant and animal parasites might help development of some generalities. Since parasities are far more numerous than predators in the world fauna, or in any particular community, emphasis on their study is justified. I freely admit that para sitoids have been usefully regarded as predators by ecologists, and many concepts on predation have been derived from their study. Also, in whichever category one places the parasitoids, that is the one which contains the most species. However, from an evolu tionary point of view they show many characteristics that must be regarded as those of a parasite. Notably, they are small, highly specific to their host, highly coevolved with it, as a result many species can coexist, and their adaptive radiation has produced the majority of the species diversity seen on Earth today. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The International Workshop on 'The Use of Super computers in Theoretical Science' took place from July 30 till August 1, 1984, at the Conference Center of the 'Priorij Corsendonk', close to the city of Antwerpen, Belgium. During the past decade computational science has developed itself to a third methodology besides the experimental and theoretical sciences. This remarkable evolution was only possible due to a drastic increase of the computational power of present day computers. Indeed, computational physics and chemistry as such is certainly not new, but it was only during the past ten years or so that realistic problems could be solved numerically to a sufficient degree of accuracy. During this workshop the state-of-the-art in high speed computation was presented by a team of lecturers who are well known for their competence in this field. It is a pleasure to thank several organizations and companies who made this workshop possible. First of all, the main sponsors: the Belgian National Science Found ation (NFWO-FNRS) and the 'Universitaire Instelling Ant werpen'. Next, the co-sponsors: Agfa-Gevaert N. V., Control Data Belgium and the Belgian Ministry of Education. Special thanks are due to Dr. P.E. Van Camp and Drs. H. Nachtegaele for the practical organization of this workshop. I would also like to thank Mrs. H. Evans for typing the manuscripts and for preparing the author and subject index. v Last but not least I express my gratitude to Mr. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The literature of medicine continues to expand at a remarkable pace. The number of papers and monographs published has increased dramatically in the past five years. Nowhere has this increase been as dramatic as in the field of acute and chronic hepatitis. Why then should there be still another book Despite the sheer volume of words published, it is still difficult to find in anyone volume a compilation of all of the most significant work. Most mono graphs have considered either chronic or acute hepatitis, not both. Few works have addressed both the clinician and the basic scientist. This book addresses both of these audiences and considers both of these diseases. It was designed to provide an authoritative but concise assessment of our changing concepts of acute and chronic hepatitis. It covers what is currently known and, based on the most convincing research, believed about these diseases. To fulfill this ambitious goal, only authors with international reputations in their fields of expertise were invited to contribute. In the evolution of our current thoughts on the pathogenesis and manage ment of acute and chronic hepatitis, our ideas have changed several times. This book presents the facts as they are known today and, in areas where all the facts are not established, presents the well-founded opinions of those considered to be authorities. The authors present established and usually confirmed data and do not deal extensively with areas of speculation or unconfirmed material. 360 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Symposium on Asymptotic Structure of Space-Time (SOASST) was held at the University of Cincinnati, June 14-18, 1976. We had been thinking of organizing a symposium on the properties of 'in finity' for several years. The subject had reached a stage of maturity and had also formed a basis for important current investi gations. It was felt that a symposium, together with a publication of the proceedings, would review, summarize, and consolidate, the more mature aspects of the field and serve as an appropriate intro duction to an expanding body of research. We had from the first the enthusiastic support and encouragement of many colleagues; with their cooperation and advice, the Symposium acquired its final form. These proceedings will attest to the value of the Symposium. The Symposium consisted of thirty lectures and had an attendance of approximately one hundred and thirty. The final impetus to our decision to go forward was the Bicen tennial Anniversary of the independence of our country. A most appropriate celebration on a University Campus surely is an intel lectual Symposium which pays honor to the histories and traditional purposes of a University. The Symposium was supported financially by the University of Cincinnatl Bicentennial Committee, the National Science Foundation, the Gravity Research Foundation, and by Armand Knoblaugh, Professor Emeritus of Physics of the University of Cincinnati. 456 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Conference on the Benthic Boundary Layer was held under the auspices of the NATO Science Committee as part of its continuing effort to promote the useful progress of science through international cooperation. Science Committee Conferences are deliberately designed to focus attention on unsolved problems, with carefully selected participants invited to provide complementary expertise from a variety of relevant disciplines. Through inten sive discussion in small groups they seek to reach a consensus on assessments and recommendations for future research emphasis, which it is hoped will be of value to the larger scientific community. The subjects treated over the past few years have been as varied as science itself-e.g., computer software engineering, chemical catalysis, and materials and energy research. The present effort evolved from informal discussions between marine geolo gists, chemists, and biologists which underlined the desirability of improved communication among those concerned with the benthic layer. In both scien tific and technological terms this is an exciting frontier, rich in promise but poorly understood at present. It is particularly striking to realize that there are at least as many definitions of the benthic layer as there are disciplines involved, and it seemed clear that there was much to be gained by a detailed exchange of views on research capabilities, trends, and priorities. The results of the meeting appear to have confirmed the hopes of the sponsors. 336 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Sherrington School of Physiology at St. Thomas' Hospital provided a natural venue for four days of enthusiastic debate on Sherrington's Final Common Path -the alpha motoneurone and related matters; Sherrington himself held a lecturership at St. Thomas' just over a century ago. The occasion was a happy one. Most participants already knew each other, the topics were familiar, the discussion was vigorous and critical but without personal rancor. The program had set out to encourage debate with 'critiques' both of the oral papers and the posters; their inclusion in the present volume helps to show where we are standing on rock rather than sand. In spite of a venerable history some surprisingly simple matters remain controversial, such as the information content of the signals from the Golgi tendon organs. To those working on alpha and gamma motoneurones and their control this volume provides an essential up-dating. Classical problems continue to be attacked on a broad front; advance is steady and continuous, a swelling tide rather than a sudden view of the summit. But in some sectors the difficulties are so great that to the outsider little might seem to change, the same battles continuing; but even here, the terms of debate change and concensus develops. Other branches of biology claim breakthrough upon breakthrough from the routine application of the new technologies, so we have to be the first to ask whether our classical approach to science can still be justified. 656 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains the lectures delivered at the NATO Advanced Study Institute on 'Physics and Applications of Quantum Wells and Superlattices', held in Erice, Italy, on April 21-May 1, 1987. This course was the fourth one of the International School of Solid-State Device Research, which is under the auspices of the Ettore Majorana Center for Scientific Culture. In the last ten years, we have seen an enormous increase in re search in the field of Semiconductor Heterostructures, as evidenced by the large percentage of papers presented in recent international conferences on semiconductor physics. Undoubtfully, this expansion has been made possible by dramatic advances in materials preparation, mostly by molecular beam epitaxy and organometallic chemical vapor deposition. The emphasis on epitaxial growth that was prevalent at the beginning of the decade (thus, the second course of the School, held in 1983, was devoted to Molecular Beam Epitaxy and Heterostructures) has given way to a strong interest in new physical phenomena and new material structures, and to practical applications that are already emerging from them. 468 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -viii beginning to understand-their action, as will be brought out in this symposium. During this same period another development took place in psychiatry, namely, social and community psychiatry, interpreted by some, incorrectly, in my opinion, as the antitheses of the biological approach. The whole area of the delivery of mental health services, which quickly became more of a political and social issue than a medical one, led to confusion, disillusionment, despair, and also soul-searching by psychiatrists and other mental health professionals. The remarkable Pablo Picasso said, 'the development of photography freed the artist to express his own creativity. ' I have paraphrased Picasso's insightful remark, namely, 'the development of biology and social and community psychiatry should free the psychiatrist to express his own creati vity as a physician. ' It should allow him to regain his basic medi cal identity. As his medical identity becomes paramount, then the pejorative classification of psychiatrists into those 'organically oriented' and those 'dynamically-oriented' will no longer be valid. The psychiatrist, like his medical colleague, must be concerned with the psychological, psychosocial, biological, and technical aspects of psychiatry. The strengthening and development of the medical identity of the psychiatrist imposes increased responsibilities on him and on psychiatry as a medical discipline. On the one hand, he will have to become more of a neuro-bi_ gist and, on the other, more of a behavioral scientist. 292 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The attractions of invertebrate nervous systems have long been appreciated by neurophysiologists. Indeed some of the milestones in our understanding of nervous systems have their foundations in experiments done on invertebrate preparations, typified by the role of the squid axon in dissect ing the events that constitute the action potential. More recently we have seen how the relatively simple nervous system of Aplysia has permitted new insights into the molecular mechanisms of memory and learning. Neurochemists, however, have not been enthusiastic about invertebrate tissues as their experimental material. Much of the biochemical information on invertebrate nervous systems that has accrued has been incidental, almost as a by-product of what were primarily physiological investigations. Fortunately the field is changing, and research groups are making a positive choice to turn to invertebrate tissues. Two important factors have contributed to this. First, the study of analogous systems in invertebrates and vertebrates can tell us much about the evolution of nervous systems. The application of the techniques of molecular genetics to the study of such molecules as receptors and ion channels can provide detailed information about their composition that, in turn, allows us to better understand their function. By extending such studies to the invertebrates we should be able to understand how such systems have developed. Secondly, invertehrate pests are responsible for enormous losses of agricultural crops and are major vectors of disease in man. 336 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is unclear, and really no longer relevant, whether the information explosion that we now contend with has been fostered by the growth of specialization and subspecialization in medicine, or vice versa. What is clear is that the two are mutually supportive and constitute what would be in endocrine parlance a short-loop positive feedback system. As a result, for most areas of medicine, even the subspecialist in that area has a problem in maintaining currency, the more general specialist has substan tial difficulty in doing so, and the generalist is tempted to abandon the effort altogether. Nevertheless, for all, both the internal pressures of conscience and self-esteem and the external pressures generated by peer review, recertifi cation, and subspecialty boards create the need for continuous self-educa tion. We are, therefore, in an era in which the means of dissemination of new information deserves as much creative attention as does its acquisition. 348 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is most appropriate that the first volume to appear in the series 'Advanced Applications in Pattern Recognition' should be this monograph by Nagao and Matsuyama. The work described here is a deep unification and synthesis of the two fundamental approaches to pat tern recognition: numerical (also known as 'statistical') and struc tural ('linguistic,' 'syntactic'). The power and unity of the meth odology flow from the apparently effortless and natural use of the knowledge-base framework illuminated by the best results of artificial intelligence research. An integral part of the work is the algorithmic solution of many hitherto incompletely or clumsily treated problems. It was on the occasion of a laboratory visit in connection with the 4th IJCPR (of ~hich Professor Nagao was the very able Program Chairman) that I saw in operation the system described here. On the spot I expressed the desire to see the work described for the inter national technical audience in this series and the authors were kind enough to agree to contribute to a new and unknown series. With the publication of this monograph on the eve of the 5th ICPR my wish is fu1fi11~d. I want to thank here the authors and Plenum Publishing Corporation for making this volume and the series a reality. 236 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The ability to 'immortalize' immunologically-useful cells by hybridization with a unique cancer cell has revolutionized serological studies and has revealed new potential applications in all fields of biological sciences. This volume presents the studies from a highly successful national symposium on Hybridomas and Cellular Immortality held November 1981 in Houston, Texas. The individual chapters exhibit the diversity of topics discussed during the meeting. These include emphasis on the origin of antibody diversity, Band T lymphocyte differentiation, applications of monoclonal antibodies in studies of histocompatibility, tumor, and viral antigens, plus the use of somatic cell hybridizations for studying T cell products. Three papers focus on the emerging methodologies of in vitro primary immunizations for both humoral and cell-mediated immunities, relevant for coupling with hybridoma technology. There is a useful mix of general (methods) and specific (applications) chapters. A unique aspect of the book is the presentation of both recent research findings with concise descriptions of the state of the art methodologies. It is anticipated that this work will be of interest to a wide audience of practioners in biomedical research. Hopefully, the information contained will foster new and imagi native ideas in hybridoma applications. Baldwin H. Tom, Ph.D. James P. Allison, Ph.D. vii CONTENTS PART L INTRODUCTION TO HYBRIDOMAS 1 Somatic Cell Hybrids and Hybridomas Baldwin H. Tom 3 1. Somatic Cell Hybrids 8 Hybridomas. - - - - - 2. 332 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On May 14-16, 1982, a group of scientists met in Viareggio, Italy to present ideas, and exchange relevant data on current approaches on immunomodulators. We felt that the embodiment of the substance of that international symposium into this volume will be beneficial in keeping both clinicians and basic scientists abreast of the latest exciting developments in this rapidly accelerating field. We hope that the publication of this series of papers by an international panel of experts will enhance the nature of future inves t igat ive stud ies with such ent it ies . Under the rubric of immunology, it is obvious that such a term as 'immunomodulation' could be construed as being all encompassing. However, it is intriguing that the immune modulators touched on in these sessions can be subcategorized into about five broad groups. Almost all substances, excepting those entities that are immuno logically inert, will have some modulating effects on immunity. From the coarse adjustment of antibody feedback inhibition upon cellular limnunity to the subtle finesse envisioned in Jerne's idiotypic network and s'lppressor T cells, immunomodulators attempt to either magnify or diminish those responses that are normally elicited by antigen. The broad groups - thymic hormones, D.L.E., Interferon, drugs, and the use of bacterial products appear to be at the forefront of much of the pioneering work on immunomodulation. 472 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One Introduction to Robotics.- Two What is a Robot .- Background.- Definitions.- Robot.- Sensing.- Programming.- Types of Automation.- Hard Automation.- Flexible Automation.- Classification of Robots.- First Generation Robots.- Second Generation Robots.- Cost Limitations.- Social Implications.- Humans Versus Robots.- Three The Mechanical Arm.- Overview.- Types of Joints.- Prismatic Joints.- Revolute Joints.- Ball and Socket Joints.- Degrees of Freedom.- Classification of Robots by Type of Joint.- Cartesian Robots.- Cylindrical Robots.- Spherical Robots.- Horizontal Articulated Robots.- Vertical Articulated Robots.- Comparison of Robot Work Envelopes.- Cartesian Robots.- Cylindrical Robots.- Spherical Robots.- Horizontal Articulated Robots.- Vertical Articulated Robots.- Suitability for Particular Tasks.- Link Construction.- Robot Arm Drive Units.- Revolute and Prismatic Drive.- Electric, Hydraulic, and Pneumatic Drive.- Electric Drive.- Hydraulic Drive.- Pneumatic Drive.- Direct and Indirect Drive.- Four The Robot Controller.- Robot Control Levels.- Actuator Control.- Closed-Loop Control.- Encoders and Tachometers.- Coordinated Control.- Path Control.- Point-to-Point Control.- Continuous Path Control.- Off-Line Programming Control and Real-Time Control.- Off-Line Programming Control.- Real-Time Control.- Controller Programming.- User Program.- Controller Software.- Five Robot Teaching Methods.- Preview.- Teaching Methods.- Teach-In.- Teach-Through.- Teach-Through Using a Force Sensor.- Teaching by Means of Other Sensors.- Programming Methods.- Definition of Coordinates by the Computer.- Shifting Coordinate Systems.- Use of Vision Sensor and Pointer.- World Modeling.- Comparison of Teaching and Programming Methods.- Six The End Effector.- Two-Finger Grippers.- Three-Finger Grippers.- Cylindrical Object Grippers.- Fragile Object Grippers.- Jointed Grippers.- Vacuum and Electromagnetic Grippers.- Automatic Gripper Changers.- Seven Integration and Operation of Robot Subsystems.- A Robot Task.- Placing block 2 on block 1.- Placing block 3 on block 2.- Implementation of the series.- Eight Industrial Applications of Robots.- Industrial Applications.- Press Loading and Unloading.- Die Casting.- Machine Tool Loading and Unloading.- Spot Welding.- Arc Welding.- Spray Painting.- Assembly.- Finishing.- Adapting Robots to Work Stations.- Requisite Robot Characteristics.- Work Envelope.- Payload.- Degrees of Freedom.- Resolution, Precision and Repeatability.- Coordination and Synchronization with Peripheral Equipment.- Non-Requisite Robot Characteristics.- Velocity of Motion.- Types of Drive.- Control and Teaching Methods.- Stages in Selecting Robots for Industrial Application.- Work Envelope.- Payload.- Degrees of Freedom.- Resolution, Precision and Repeatability 150 Coordination and Synchronization with Peripheral Equipment.- Non-Requisite Robot Characteristics.- Nine Sensors and Sensing.- Artificial Intelligence.- Human Versus Artificial Senses.- Sensor Types.- Contact Sensors.- Single-Contact Sensors.- Multiple-Contact Sensing Surfaces.- Contact Sheets.- Slipping Sensors.- Whiskers.- Force and Moment Sensors.- Force and Moment Sensor Applications.- Use of Force and Moment Sensors in Finishing Applications.- Problems in the use of Force and Moment Sensors.- Non-Contact Sensors.- Identification of a Part with a Single Detector.- Sensing Array (Line) Identification.- Sensing Matrix Camera (Surface).- Identification.- Ten Future Developments.- Preview.- Unmanned Factories.- Personal Robots.- Man-Machine Communications.- Artificial Bodies.- Conclusion. 236 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For my past sins, Leslie Ettre has given me the privilege of writing a few words to preface his excellent little book. It gives me great pleasure to do so, because of the many years of fruitful collabo ration we have had at Perkin-Elmer, because it is refreshing to see a treatise in gas chromatography in which the theoretical treatment has been bared to its essentials, without a mushrooming of formulae which, by means of an ever increasing number of parameters, account for more and more, and explain less and less, and because the author has recognized that the gas chromatographic column is a nearly passive element in its own right which deserves to have a treatise written nearly exclusively about it, just as electrical circuit theory can be discussed without elaborate references to vacuum tubes and meters. I wish this conscientiously written volume the success it deserves. M. J. E. GOLAY VII Preface Gas chromatography is a separation technique used primarily in analytical chemistry. Therefore, it is evident that special emphasis should be placed on that particular part of the apparatus in which the separation takes place. This part is the column, the heart of the gas chromatograph. The goal of researchers in the field of gas chromatography has been-from the beginning-to understand the separation process so that they might design columns with the best possible performance. Such investigation led M. J. E. 188 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -According to the classical concept of Geoffrey Harris the pituitary gland is controlled by the brain by means of blood-borne chemical messengers produced by central neurons. The recent isolation and structural characterization of several such messengers by Roger Guillemin and Andrew Schally and their collaborators brought the final proof for this hypothesis. This also meant that the extensive knowledge collected in the field of neurobiology now became highly relevant for the endocrinologists. For this reason it was felt important to organize a symposium which brought together experts in the fields of neurobiology and endocrinology. The idea was to focus the attention on neuronal mechanisms, particularly those related to chemical transmission, which may be of importance for the central regulation of hormonal secretion patterns. We would like to express our sincere gratitude to the Nobel Founda tion for supporting the organization of the Nobel Symposium 42 on 'Principles of the Central Regulation of the Endocrine System'. We would also like to express our thanks to all participants, to Professor Carl-Gustaf Bernhard, Permanent Secretary of the Royal Academy of Sciences, for making the facilities of the Academ- available to us, and to the Symposium secretaries Mrs. Gun Hultgren, Mrs. Lena Persson and Mrs. Ulla-Britt Wedin. It is a pleasure to acknowledge the generous financial support from the Nobel Foundation and its Nobel Symposium Committee through grants from the Tercentenary Foundation of the Bank of Sweden, and from the Swedish Medical Research Council, KABI AB, Stockholm, and ASTRA AB, Sodertalje. 572 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume derives from papers presented at the 4th biennial meeting of the Italian Biophysical Society, held in Parma in October 1979. It includes review lectures presented by guest scientists (R.H. Adrian, E. Neher, S. Ottolenghi, and G. Zaccai); the remaining reviews and papers present some of the problems currently under study in our country. One can see that biophysical problems are studied under differ ent academic roofs, i.e., at physiological or biochemical departments. We consider this a strength and a weakness at the same time. The 'Italian Bioenergetics Group' contributed to the success of the meeting, as much as the groups working in various laboratories of the Consiglio Nazionale delle Ricerche, in particular those of the National Group of Cybernetics and Biophysics. To them, and to the University of Parma, which contributed financial and organiza tional support, the Editors of this volume wish to express their appreciation. Particular thanks are to Drs. E. Carbone and V. Lenci, who spent time and effort for the meeting and in collecting the papers. The special care in the typing goes to the credit of Miss Rampello, to whom the Editors express their deepest gratitude. 380 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The clinical trials program of anti-tumor drugs was started by the National Cancer Institute in 1955. In the past 15 years, this national network has collected a large body of data on all of the recognized anti-tumor drugs as well as upon new, experimentally promising agents. While the most important of these studies have been published, there has remained a wealth of data not generally available to the scientific community. Drs. Carter and Livingston have not only succeeded in organ~z~ng this large corpus, they have in addition analyzed and interpreted the clinical data in a way that will be highly useful for years to come. From a perusal of this volume it becomes apparent that some drugs are more active against certain tumors than had been realized; that the evidence for the activity of certain drugs against specific tumors is sometimes tenuous; surprisingly, that some highly active agents have never been tried against some of the fairly common tumors. Their monumental work has provided not only access to the hard data, it has also shown the need for research to fill in important gaps in our knowledge. The authors and the IFI/Plenum Press are to be congratulated for this useful and important work. C. Gordon Zubrod, M. D. Scientific Director for Chemotherapy National Cancer Institute National Institutes of Health Bethesda, Maryland v Acknowledgment The authors wish to thank Dr. C. Gordon Zubrod and Dr. 420 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a work of conscience. It is the product of a long-standing feeling of obligation on my part to write something useful for a special group of people to which you probably belong-individuals who seek grants. In my years as Director of the New York library of The Foundation Center, \* each and every day I encountered numbers of individuals look ing for grant money. Although I tried to be as supportive as possible, in the face of the particular problems shared by this group of library users, my own reaction was one of relative helplessness. Simply stated, most of the fund-raising guides, printed directories, and computer files purport edly created to serve the fund-raising public are of little or no use to individuals who seek funding on their own. These resources are directed \*The Foundation Center is the independent, nonprofit organization established by foun dations to provide information for the grant-seeking public. vii viii I PREFACE toward the nonprofit, tax-exempt agency, which is the most common recipient of foundation, corporate, and government largess. They are not designed to respond to the special requirements of the individual grant seeker. In the applicant eligibility index, the Catalog of Federal Domestic Assistance defines individuals as 'homeowners, students, farmers, artists, scientists, consumers, small-business persons, minors, refugees, aliens, veterans, senior citizens, low-income persons, health and educational professionals, builders, contractors, developers, handicapped persons, the physically afflicted.' In short, practically everyone qualifies. 316 pp. Englisch.