springer chapman and hall crc okt 2012 (79 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -membrane contamination and thus could then be used to study transport function when pre pared as membrane vesicles. These approaches defined a number of transport functions in the plasma membranes of hepatocyres and ultimately led to the recognition that bile salts and 3 25 other solutes were transported into bile largely by ATP dependent transport mechanisms.2 - The advent ofmolecular cloning techniques and cellular expression systems rapidly acceler ated progress in this field and led to the molecular characterization ofmost ofthe major mem brane transport proteins that determine both the hepatic uptake of organic solutes as well as bile salt dependent and bile salt independent canalicular excretion. Overview of the Molecular Mechanisms of Bile Formation The major transporters that determine bile formation are illustrated in Figure 1 and are discussed in greater detail in the subsequent chapters. The enrerohepatic circulation ofbile salts maintains bile salt dependent bile flow. Bile salts are excreted into bile and are largely absorbed in the terminal ileum and then efficiently removed from the portal circulation at the basolateral plasma membrane of the heparocyte. Each of these steps is dependent on the function of bile salt transport proteins. 384 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the period of about five years since the first edition of this book appeared, many changes have occurred in the fruit juice and beverage markets. The growth of markets has continued, blunted to some extent, no doubt, by the recession that has featured prominently in the economies of the major consuming nations. But perhaps the most significant area that has affected juices in particular is the issue of authenticity. Commercial scandals of substantial proportions have been seen on both sides of the Atlantic because of fraudulent practice. Major strides have been made in the development of techniques to detect and measure adulterants in the major juices. A contri bution to Chapter 1 describes one of the more important scientific techniques to have been developed as a routine test method to detect the addition of carbohydrates to juices. Another, and perhaps more welcome, development in non-carbonated beverages during the past few years is the rapid growth of sports drinks. Beverages based on glucose syrup have been popular for many years, and in some parts of the world isotonic products have long featured in the sports arena. A combination of benefits is now available from a wide range of preparations formulated and marketed as sports drinks and featuring widely in beverage markets world-wide. A new chapter reviews their formulation and performance characteristics. Another major trend in the area offruit-containing non-carbonated bever ages is the highly successful marketing of ready-to-drink products. 448 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Human reproduction is the most dynamic of processes. The events which lead to the birth of a normal healthy infant have their origin long before actual fertilization. Indeed, the whole process can be looked upon as a continuum. Human fertilization and early development, once sequestered in the protective environment of the fallopian tubes and uterus, have now been exposed in the laboratory. These events have, over time, been extensively observed and catalogued in animal models. The tools of modem morphology and molecular biology have reopened issues long since considered settled as facets of early reproduction are reexplored. This volume, consisting of the proceedings of a workshop on uterine and embryonic factors in early pregnancy, has been designed to enhance that effort. Attention is focused largely on early embryonal development with special attention to the interrelationship between the embryo and the uterus in early pregnancy. Each of the contributing scientists brings with him or her the perspective of one specific discipline or another. The common denominator is the application of emerging techniques in modem molecular biology to problems pertaining to embryonal-uterine interaction. The goal is to consider specific areas of concern in a multidisciplinary way and to reexplore the factors behind early development and implantation. Uterine complement, the function of uterine macrophages immunoregulatory loops in the peri-implantation period, colony stimulating factors and interferon-like factors are reviewed and their interrelationship explored. Uterine angiogenesis factors as well as embryonic growth factors are also considered. 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologists, identify missing links, and catalyze new ideas. (2) To relate basic microscale phenomena to the global, clinically manifested cardiac function. (3) To relate conceptual modeling and quantitative analysis to experimental and clinical data. (4) To encourage international cooperation so as to disperse medical and technological knowhow and lead to better understanding of the cardiac system. The first Henry Goldberg Workshop, held in Haifa in 1984, introduced the concept of interaction between cardiac mechanics, electrical activation, perfusion, and metabolism, emphasizing imaging in the clinical environment. The second Workshop, in 1985, discussed the same parameters with a slant towards the control aspects. The third Goldberg Workshop, held in the USA at Rutgers University in 1986, highlighted the transformation of the microscale activation phenomena to macroscale activity and performance, relating electrophysiology, energy metabolism, and cardiac mechanics. The fourth Goldberg Workshop, in 1987, continued the effort to elucidate the interactions among the various parameters affecting cardiac performance, with emphasis on the ischemic heart. The fifth Workshop, held in Cambridge, UK, in 1988, dwelt on the effects of inhomogeneity of the cardiac muscle on its performance in health and disease. The sixth Workshop highlighted the role of new modem imaging techniques, that allow us to gain more insight into local and global cardiac performance in cardiac research and clinical practice. 376 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism. It will provide a deeper understanding of the pathogen to physicians and surgeons caring for patients infected, or at risk of becoming infected, with Pseudomonas Aeruginosa. 444 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -InhaltsangabeThe future of behavioral pharmacology.- Session I Environmental Influences Affecting the Voluntary Intake of Drugs.- Environmental influences affecting the voluntary intake of drugs: an overview.- An experimental analysis of behavioral factors in drug dependence.- Second-order schedules of drug injection.- Behavioral functions of narcotic antagonists: response-drug contingencies.- Experimental models for the modification of human drug self-administration: Methodological developments in the study of ethanol self-administration by alcoholics.- Session II Interactions of Behavioral and Neurochemical Processes.- On neurochemistry and behavior.- Behavioral correlates of serotonin depletion.- Neurochemical changes associated with schedule-controlled behavior.- Serotonergic and cholinergic mechanisms during disruption of approach and avoidance behavior.- Catecholamines and drug-behavior interactions.- Session III Behavioral Toxicology.- Behavioral toxicology: A developing discipline.- Assessing the impact of low level chemicals on development: behavioral and latent effects.- Amphetamine toxicity: behavioral and neuropathological indexes.- Psychophysical evaluation of toxic effects on sensory systems.- Behavioral effects of mercury and methylmercury.- Session IV Contingencies of Reinforcement as Determinants of Drug Response.- Schedule-controlled behaviors as determinants of drug response.- Determinants of drug effects on punished responding.- The role of discriminative stimuli in modulating drug action.- Reinforcement schedules and extrapolations to humans from animals in behavioral pharmacology.- Discrete trial analysis of drug action. 316 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Environmental Systems Engineering and Economics emphasizes the application of optimization, economics, and systems engineering to problems in environmental resources management. This senior level/graduate textbook introduces optimization theory and algorithms that have been successful in resolving water quality and groundwater management problems. Both linear programming and nonlinear optimization are presented. Multiobjective optimization and the linked simulation-optimization (LSO) methodology are also introduced. The basic principles of economics and engineering economics are also discussed to provide a framework for economic decision making. This text contains numerous example problems. Case studies are presented that address water resources management issues in the north China plain, the control of saltwater intrusion in Jakarta, Indonesia, and groundwater resources management in the Yun Lin basin, Taiwan. 488 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Milk has played a major contribution to the human diet in many different countries across the world since the dawn of time. The dairy cow was domesticated over 6000 years ago, she was the object of worship in the Middle East 2000 years before Christ, and milk and milk products are mentioned more than 50 times in the Bible. Milk and dairy products have become a major part of the human diet in many countries. It is not surprising therefore, that over many years considerable attention has been paid to improving the quality of milk. We have worked to improve the yield, the compositional quality and the hygienic quality, and have striven to minimise the level of contaminants which can find access to this, perhaps our most natural, unrefined and highly nutritious foodstuff. The chain of people involved in the milk industry extends from milk production-farmers, veterinarians and farm advisors-through transport to processing-quality controllers, manufacturers-and on to retailers, legislators,nutritionists, dairy educators and consumers. All will be interested in the quality parameters of milk which are reg ularly measured for commercial reasons, for trade, for legal requirements and for reasons of nutrition. 184 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present book contains a comparison of existing theoretical models developed in order to describe membrane separation processes. In general, the permeation equations resulting from these models give inaccurate predictions of the mutual effects of the permeants involved, due to the simplifications adopted in their derivation. It is concluded that an optimum description of transport phenomena in tight (diffusion-type) membranes is achieved with the 'solution-diffusion' model. According to this model each component of a fluid mixture to be separated dissolves in the membrane and passes through by diffusion in response to its gradient in the chemical potential. A modified Flory-Huggins equation has been derived to calculate the solubility of the permeants in the membrane material. Contrary to the original Flory-Huggins equation, the modified equation accounts for the large effect on solubility of crystallinity and elastic strain of the polymer chains by swelling. The equilibrium sorption of liquids computed with this equation was found to be in good agreement with experimental results. Also, the sorption of gases in both rubbery and glassy polymers could be described quan titatively with the modified Flory-Huggins equation without any need of the arbitrary Langmuir term, as required in the conventional 'dual-mode' sorption model. Furthermore, fewer parameters are required than with the at least identical accuracy. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From the 19-29 May 1991 the NATO ASI Course PAsthma Treatment: A P Multidisciplinary Approach was held in Erice, on the rocky North West Coast of Sicily, facing the ancient Phoenician shore of the African Continent. Sixty NATO sponsored participants arriving from many different European Countries - Nato members and non - attended the course. Qualified researchers from Europe and the United States held extensive lectures, short meetings and small informal group discussions. Erice is a magical place which draws together people from different backgrounds and cultures under her Mediterrean charm, recreating the ancient Greek openair discussion atmosphere. And so, during the 10 days gathering, the extensive willingness of the senior investigators and the laudable enthusiasm of the younger participants was stimulated. All of the most recent findings in the biology and the pharmacology of Asthma were discussed, initially behind closed doors, to be unhurriedly continued along the alley ways of the 'Cittadella della Scienza' , in Erice's small restaurants, and on her deserted beaches. The texts collected here are testimony to the high quality of the investigators contributions as well as their far reaching interests. I think that a Director of such a Course would be adequatly satisfied by merely considering the enthusiasm and high level involvement of every participant. He could not have been more satisfied after having considered the proceedings summerizing the scientific content of the meeting. 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Covering both the theoretical and applied aspects of electrochemistry, this well-known monograph series presents a review of the latest advances in the field. 568 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The idea of the workshop on Functional Integration, Theory and Applications, held in Louvain-Ia-Neuve from November 6 to 9 1979, was to put in close and informal contact, during a few days, active workers in the field. There is no doubt now that functional integration is a tool that is being applied in all branches of modern physics. Since the earlier works of Dirac and Feynman enormous progress has been made, but unfortunately we lack still a unifying and rigo rous mathematical framework to account for all the situations in which one is interested. We are then in presence of a rapid ly changing field in which new achievements, proposals, and points of view are the normal pattern. Considering this state of affairs we have decided to order the articles starting from the more fundamental and ambitious from the point of view of mathematical rigour, followed by ar ticles in which the main interest is the application to con crete physical situations. It is obvious that this ordering should not be taken too seriously since in many cases there will be an interplay of both objects. 368 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A decade ago, for most scientists investigating various issues in life sciences the word 'NO' was used in a negative context. It is astounding to observe how recently researchers are addressing the issue of NO, namely, nitric oxide, in over fifty publications weekly. Science journal, while naming nitric oxide: 'Molecule of the Year' (December 1992), said it all: 'NO news is good news. ' For a long period of time NO was considered as a pollutant and every ecology minded person tried to eliminate it. It was the discovery of NO involvement in the process of host killing by macrophages and several years later the finding that EDRF is none else but NO, that promoted this field. Nitric oxide's major role in the control of blood pressure is merely one factor of an extensive list of effects and functions attributed to it. NO is implicated in long-term potentiation (LPT), a principal process involved in memory consolidation and it is considered as the main biochemical substance responsible for penile erection. It should be noted that additional roles for NO are discovered continuously as many laboratories join the quest for the mystery of this small molecule. The observation that NO is involved in various biological processes is not unique, as other second messengers (i. e. , cyclic AMP), participate in a diverse set of functions. 264 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The principles of fluorescence spectroscopy are by now well established, and, after a rather lengthy gestation period, the technique is now routinely applied to a broad spectrum of problems, ranging from mechanistic photo chemistry to chemical analyses in biomedical and environmental systems to probes of structure and function in biological macromolecules. Phosphor escence spectrometry and chemiluminescence are also well-known tech niques; they are somewhat less well established than fluorescence (at least in analytical chemistry), but they too are receiving greatly increased appli cation to both laboratory and 'real' problems. This is not to imply that luminescence spectroscopy, viewed in its broadest sense, is a static field. In fact, recent advances in instrumentation make it feasible to apply fluorescence to problem areas in which its use five years ago would have been unthinkable. Advances in hardware generate advances in application, and very significant progress is being recorded in the application of fluorescence (and its close relatives, phosphorescence and chemiluminescence) in the biochemical, biomedical, and environmental spheres. 480 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The enormous impact of both clinical and basic research on the field of breast cancer can now be readily appreciated. It is the purpose of this new series of books to bring together the recent major advances in our understanding of the disease. The first volume is devoted exclusively to treatment. It is written by scholars who are actually investigating the biological principles which underlie our current approaches to therapy. For example, countless articles have appeared proposing some ad vantage for one surgical approach to primary breast cancer compared with another. The new message is that these arguments for the superior ity of one surgical approach over a.nother are valid only in that minority of patients whose disease is absolutely confined to the primary tumor site. It is far less important which surgical approach is selected for the larger group of patients who present with occult distant metastases. The whole subject of adjuvant therapy is still in its infancy. We have progressed from single-agent adjuvant chemotherapy to combined modality regimens consisting of combination chemotherapy plus im munotherapy, plus radiotherapy, plus endocrine therapy. It will un doubtedly take many years to sort out the proper use of these agents. 400 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aging process, like most (all ) things in the universe, is a puzzle. It is such a fundamental occurrence, common to all living things, that it ironically may be the most complicated and perplexing puzzle to solve. There are, of course, puzzles sufficient in number to occupy all the scientists and philosophers who have ever lived a thousand times over. Yet what other phenomenon affects everyone of us as much as growing old Curiosity about the ubiquity of aging as a phenomenon, boosted perhaps by an only natural fear of that same phenomenon as an undeniable manifes tation of our own mortality, has led to the compilation of data on the aging process, which have accumulated as rapidly as the elderly who might benefit from those data. Most of the scientific data on the biology of aging are at the biochemical and physiological levels, while comparatively little information has been avail able at the anatomical level. Because of this, a two-volume set called Aging and Cell Structure was conceived, the first volume having been published in 1981 and the second volume being published concurrently with the present one on cell function. The emphasis on training of scientists and other individuals in advanced education has, during past decades, been one of increased specialization. Not merely do we specialize in physiology, anatomy, zoology, or literature, but in glomerular filtration, synaptic junctions, tree frogs of Brazil, or English poetry of the nineteenth century. 300 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The NATO . Advanced Research Insti tute on Nonequilibrium Processes in Partially Ionized Gases was held at Acquafredda di Maratea during 4-17 June 1989. The Institute considered the interconnections between scattering and transport theories and modeling of nonequilibrium systems generated by electrical discharges, emphasizing the importance of microscopic processes in affecting the bulk properties of plasmas. The book tries to reproduce these lines. In particular several contributions describe scattering cross sections involving electrons interacting with atoms and molecules in both ground and excited states (from theoretical and experimental point of view), of energy transfer processes as well as reactive ones involving excited molecules colliding with atoms and molecules as well as with metallic surfaces. Other contributions deal with the basis of transport theories (Boltzmann and Monte Carlo methods) for describing the bulk properties of non equilibrium plasmas as well as with the modeling of complicated systems emphasizing in particular the strong coupling between the Boltzmann equation and excited state kinetics. Finally the book contains several contributions describing applications in different fields such as Excimer Lasers, Negative Ion Production, RF Discharges, Plasma Chemistry, Atmospheric Processes and Physics of Lamps. The Organizing Committee gratefully acknowledges the generous financial support provided by the NATO Science Committee as well as by Azienda Autonoma di Soggiorno e Turismo of Maratea, by University of Bari, by C. N. R. (Centro di Studio per la Chimica dei Plasmi and Comitato per la Chimica), by ENEA, by Lawrence Livermore Laboratory and by US Army Research Office. 712 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The exponential growth of Internet brings to focus the need to control such large scale networks so that they appear as coherent, almost intelligent, organ isms. It is a challenge to regulate such a complex network of heterogeneous elements with dynamically changing traffic conditions. To make such a sys tem reliable and manageable, the decision making should be decentralized. It is desirable to find simple local rules and strategies that can produce coherent and purposeful global behavior. Furthermore, these control mechanisms must be adaptive to effectively respond to continually varying network conditions. Such adaptive, distributed, localized mechanisms would provide a scalable so lution for controlling large networks. The need for such schemes arises in a variety of settings. In this monograph, we focus on localized approach to quality of service routing. Routing in the current Internet focuses primarily on connectivity and typi cally supports only the 'best-effort' datagram service. The routing protocols deployed such as OSPF use the shortest path only routing paradigm, where routing is optimized for a single metric such as hop count or administrative weight. While these protocols are well suited for traditional data applications such as ftp and telnet, they are not adequate for many emerging applications such as IP telephony, video on demand and teleconferencing, which require stringent delay and bandwidth guarantees. The 'shortest paths' chosen for the 'best effort' service may not have sufficient resources to provide the requisite service for these applications. 128 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Analyzing the findings of 20 studies, involving more than 5,000 people, this book explores the decision making process of the crime victim in the immediate aftermath of victimization. Using a broad range of innovative research techniques, the authors assess the effects of rape, robbery, burglary, and theft on individuals from diverse nationalities and ethnic backgrounds. This work will be of value to people who work directly with crime victims, and to researchers who are interested in the process of decision making under stressful circumstances. 312 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume chronicles the proceedings of the Third Symposium on Metallized Plastics: Fundamental and Applied Aspects held under the auspices of the Dielectric Science and Technology Division of the Electrochemical Society in Phoenix, Arizona, October 13-18, 1991. This series of symposia to address the subject of metallized plastics was initiated in 1988 and the premier symposium was held in Chicago, October 10-12, 1988, followed by the second event in Montreal, Canada, May 7-10, 1990. The rroceedings of these two symposia have been properly documented ,2. The third symposium was a huge success like the previous two events, and all this is testimonial to the brisk interest and high tempo of R&D activity in the fie14 of metallized plastics. This further bolsters our earlier thinking that there was a conspicuous need to hold symposia on this topic on a regular basis and the fourth is planned for May 16-21, 1993 in Honolulu, Hawaii. The study of metallized plastics constitutes an important human endeavor l and as pointed out earlier there are myriad applications of metallized plastics ranging from very commonplace to exotic. Also a survey of the recent literature will reveal that both the fundamental and applied aspects of metallized plastics are being pursued with great vigor. 416 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is based on contributions to the NATO Advanced Research Workshop on Recombination of Atomic Ions. This was held at the Slieve Donard Hotel in Newcastle, Northern Ireland, between 6 and 9 October 1991 and attracted 35 participants from 5 countries. The book is inter.~ed to serve as an in-depth review of work to this date on the subject of recombination of atomic ions both in collision with free electrons and with atoms. It contains contributions from almost all groups which have made significant contributions in this area during the last decade. In addition, a synopsis of the discussion session following each of the main subject areas is presented. The material is organized into several themes; an overview of the subject area, theoretical aspects of recombination, experimental measurements of electron-ion recombination and experimental measurement.s of recombination in ion-atom collisions. We would like to acknowledge the sponsorship of the NATO Scientific Affairs Division. We would like to thank the Northern Ireland Tourist Board and the Queen's University of Belfast for providing some additional funding. Finally we would like to thank all the contributors to these proceedings for their efforts in preparing the manuscripts and their assistance in the editing process. 356 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One criterion for classifying books is whether they are written for a single purpose or for multiple purposes. This book belongs to the category of multipurpose books, but one of its roles is predominant-it is primarily a textbook. As such, it can be used for a variety of courses at the first-year graduate or upper-division undergraduate level. A common characteristic of these courses is that they cover fundamental systems concepts, major categories of systems problems, and some selected methods for dealing with these problems at a rather general level. A unique feature of the book is that the concepts, problems, and methods are introduced in the context of an architectural formulation of an expert system referred to as the general systems problem solver or GSPS-whose aim is to provide users of all kinds with computer-based systems knowledge and methodology. The GSPS architecture, which is developed throughout the book, facilitates a framework that is conducive to a coherent, comprehensive, and pragmatic coverage of systems fundamentals--concepts, problems, and methods. A course that covers systems fundamentals is now offered not only in systems ~cience, information science, or systems engineering programs, but in many programs in other disciplines as well. Although the level of coverage for systems science or engineering students is surely different from that used for students in other disciplines, this book is designed to serve both of these needs. 560 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The eleventh monograph and meeting of the Foundation on 'Hormon al Control of the Hypothalamo-Pituitary-Gonadal Axis' was held in October 1983 at the Weizmann Institute of Science. This monograph honors the memory of Professor Hans R. Lindner, a productive and innovative scientist greatly respected and admired by his col leagues. When addressing the opening session I remarked that my impres sion of the Weizmann Institute was one or two large buildings hous ing the various departments. This was my first visit to Israel and I was overwhelmed by the beautiful semi-tropical gardens of the in stitute, in a setting of shrubs and trees, orange groves and flow ers. Sited among this seventy-five acres are over fifty buildings and residential areas for the staff and visiting scientists. I saw pictures of this area when Dr. Chaim Weizmann founded in 1934, the Daniel Sieff Research Institute, the forerunner of the Weizmann In stitute. The site was sand dunes without a blade of grass. That the desert shall bloom is illustrative of the progress made in Is rael. The topics of the monograph are grouped into twelve sections. 640 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the first half of a text for a two semester course in mathematical statistics at the senior/graduate level for those who need a strong background in statistics as an essential tool in their career. To study this text, the reader needs a thorough familiarity with calculus including such things as Jacobians and series but somewhat less intense familiarity with matrices including quadratic forms and eigenvalues. For convenience, these lecture notes were divided into two parts: Volume I, Probability for Statistics, for the first semester, and Volume II, Statistical Inference, for the second. We suggest that the following distinguish this text from other introductions to mathematical statistics. 1. The most obvious thing is the layout. We have designed each lesson for the (U.S.) 50 minute class; those who study independently probably need the traditional three hours for each lesson. Since we have more than (the U.S. again) 90 lessons, some choices have to be made. In the table of contents, we have used a \* to designate those lessons which are 'interesting but not essential' (INE) and may be omitted from a general course; some exercises and proofs in other lessons are also 'INE'. We have made lessons of some material which other writers might stuff into appendices. Incorporating this freedom of choice has led to some redundancy, mostly in definitions, which may be beneficial. 448 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the proceedings of the NATO Advanced Study Institute held in Porto Conte (Alghero), Sardinia, September 15-27, 1991. The A. S. 1. was attended by 86 graduate and postgraduate students from 18 different countries, and was hosted by the newly founded International Laboratory of Molecular Genetics of Porto Conte, directed by Prof. Marcello Siniscalco. The A. S. I. was funded by NATO Scientific Affairs Division, the International Union of Immunological Societies, the European Community (Directorate General for Science, Research and Development), the Italian Research Council, and the San Raffaele Institute of Milano. In addition, a number of students who reside in the U. S. received travel funds from the U. S. National Science Foundation, and the Turkish National Fund provided financial assistance to several students from Turkey. When we decided to organize a course on T lymphocytes, our concern was to reach a balance between the teaching of both the hard core principles and the latest experimental findings of cellular immunology, and the recently expanded interfaces with the not-yet known: hypotheses, speCUlations, new projections to be born from the discussions. 272 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These volumes, 9 and 10, of Fracture Mechanics of Ceramics constitute the proceedings of an international symposium on the fracture mechanics of ceramic materials held at the Japan Fine Ceramics Center, Nagoya, Japan on July 15, 16, 17, 1991. These proceedings constitute the fifth pair of volumes of a continuing series of conferences. Volumes 1 and 2 were from the 1973 symposium, volumes 3 and 4 from a 1977 symposium, and volumes 5 and 6 from a 1981 symposium all of which were held at The Pennsylvania State University. Volumes 7 and 8 are from the 1985 symposium which was held at the Virginia Polytechnic Institute and State University. The theme ofthis conference, as for the previous four, focused on the mechanical behavior ofceramic materials in terms of the characteristics of cracks, particularly the roles which they assume in the fracture processes and mechanisms. The 82 contributed papers by over 150 authors and co-authors represent the current state of that field. They address many of the theoretical and practical problems ofinterest to those scientists and engineers concerned with brittle fracture. 620 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The volumes 11 and 12 of Fracture Mechanics of Ceramics constitute the proceedings of the 6th International Symposium on Fracture Mechanics of Ceramics held at the Research Center Karlsruhe, Germany, July 18,19,20,1995. As in previous conferences the state of the art of the failure behaviour of monolithic engineering ceramics and of reinforced ceramics was discussed. The 90 papers by over 200 authors and co-authors address the recent devel opments in the understanding and the modelling of the fracture processes in brittle materi als. The main topics are R-curve behaviour, toughness determination, surface effects, com posite materials, high temperature behaviour, ceramic-metal joints, fatigue. The program chairmen gratefully acknowledge the financial support of the Deutsche Forschungsgemeinschaft (German Science Foundation) which made possible the participa tion of scientists from East Europe. We also thank Mrs. Eva Schroder from the Research Cen ter Karlsruhe, the local organization committee (Dirk Hertel, Claus Petersen, Dr. Franz Porz, Rainer Weif3) and the conference secretary Mrs. Lucia Borchardt for their conscientious and efficient organization of all details of the conference, Mrs. Isabella Daubenthaler and Mrs. Natascha Rothweiler for preparing the booklet of abstracts and Dr. Theo Fett for his help in editing the proceedings. 608 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume continues the development of the Modern Aspects series in the electrochemical field. The series is now 18 years old, and it is relevant to note the degree of evolution that electro chemistry has undergone during this time, for it affects the character of the articles chosen. The trend is towards development of inter disciplinary areas of electrochemical science, with full stress upon the many directions of applications of knowledge of electrode processes. The degree of import which should be attached to electro chemical science arises from the changes in technology which must be made during the next few decades. These clearly involve a massive electrification and the gradual elimination of the present fossil fuel economy, for both ecological and economic reasons. Research on the fundamental aspects of the field-slow in development to a standard-must be promulgated, but its justification is the modern provisionofa basis for the needed future electrochemical technology. One vast area of potential application of electrochemical concepts is omitted by the present attitude. It is, of course, the electro biological aspect, perhaps, finally, the largest area of all for fruitful applications. These concepts are reflected in the editors' choice of chapters. Quantum mechanical descriptions of surfaces must be bravely faced. Oscillatory aspects of electrochemical systems are often met in nature and demand attention at a fundamental level. Organic electrochemistry is in an ascending phase. With the electro biological v Preface vi article, we hope to stimulate a beginning of electrodic applications in this area. 360 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The seventh Annual Pezcoller Symposium entitled, Cancer Genes: Functional As pects, was held in Trento, Italy, June 14-16, 1995 and was focused on oncogenes func tion, tumor suppressor gene function, transcription regulation, cell cycle progression regulation and apoptosis, and the clinical implications of oncogene function and regula tion for prevention and therapy of cancer. With presentations at the cutting edge of pro gress and stimulating discussions, this Symposium addressed issues related to the mechanisms of control of cell growth and death by certain genes such as c-myc, src, fyns, bcl2, the function of cdk inhibitors, the functions of p53 and WTI, the mechanisms of transcriptional activation of specific oncogenes, the genetic characterization of certain he matological malignancies, the interference with specific sites along signal transduction and the genetic alterations of tumor immunity. We wish to thank the participants in the Symposium for their substantial contribu tions and their participation in the spirited discussions which followed. We would also like to thank Drs. Jane Azizkhan, Paolo Comoglio, Giulio Draetta~ David M. Livingston and Alex Matter for their essential input as members of the Program Committee, and Ms. A. Toscani for her invaluable assistance. The aid of the Bank Cassa di Risparmio di Trento and Rovereto, and the Municipal, Provincial and Regional Administrations in sup porting this Symposium through the Pezcoller Foundation are also acknowledged with deep appreciation. Finally, we wish to thank the staff of Plenum Publishing Corporation for their efficient cooperation in the production of these Proceedings. 300 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of this Advanced Research Workshop was to bring together Physicists, Applied Mathematicians and Fluid Dynamicists, including very specially experimentalists, to review the available knowledge on the global structural aspects of turbulent flows, with an especial emphasis on open systems, and to try to reach a consensus on their possible relationship to recent advances in the understanding of the behaviour of low dimensional dynamical systems and amplitude equations. A lot has been learned during recent years on the non-equilibrium behaviour of low dimen sional dynamical systems, including some fluid flows (Rayleigh-Benard, Taylor-Couette, etc. ). These are mostly closed flows and many of the global structural features of the low dimensional systems have been observed in them, including chaotic behaviour, period doubling, intermit tency, etc. . It has also been shown that some of these flows are intrinsically low dimensional, which accounts for much of the observed similarities. Open flows seem to be different, and experimental observations point to an intrinsic high dimensionality. However, some of the tran sitional features of the low dimensional systems have been observed in them, specially in the intermittent behaviour of subcritical flows (pipes, channels, boundary layers with suction, etc. ), and in the large scale geometry of coherent structures of free shear flows (mixing layers, jets and wakes). 392 pp. Englisch.