springer japan springer japan aug 2014 (71 risultati)

Taschenbuch. Condizione: Neu. Neuware -This book focuses on the fundamental concept of and current endeavors in ¿urban mining¿ among those who are interested in both metal resources and ecology. Systems for recycling and reusing precious metals and rare-earth minerals contained in used and discarded electronics are introduced in this book. The target audience is not academic researchers in the resource management and ecology fields but, rather, citizens who are concerned about our future environment and want to do something for the future.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 60 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Magnetic resonance cholangiopancreatography (MRCP) is a newly developed noninvasive diagnostic technique for sectional and projectional imaging of the pancreatobiliary tree. Requiring no contrast materials, MRCP provides high-quality 2-D and 3-D images that facilitate early diagnosis and treatment of pancreatobiliary diseases. The authors draw upon their experience of more than 3000 MRCP studies as they illustrate the usefulness of this important new diagnostic modality. This volume is a valuable resource with state-of-the-art information for practitioners, researchers, and others in the fields of gastroenterology, radiology, and surgery.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 168 pp. Englisch.

Buch. Condizione: Neu. Neuware -Applied data-centric social sciences aim to develop both methodology and practical applications of various fields of social sciences and businesses with rich data. Specifically, in the social sciences, a vast amount of data on human activities may be useful for understanding collective human nature. In this book, the author introduces several mathematical techniques for handling a huge volume of data and analysing collective human behaviour. The book is constructed from data-oriented investigation, with mathematical methods and expressions used for dealing with data for several specific problems. The fundamental philosophy underlying the book is that both mathematical and physical concepts are determined by the purposes of data analysis. This philosophy is shown throughout exemplar studies of several fields in socio-economic systems. From a data-centric point of view, the author proposes a concept that may change people¿s minds and cause them to start thinking from the basis of data. Several goals underlie the chapters of the book. The first is to describe mathematical and statistical methods for data analysis, and toward that end the author delineates methods with actual data in each chapter. The second is to find a cyber-physical link between data and data-generating mechanisms, as data are always provided by some kind of data-generating process in the real world. The third goal is to provide an impetus for the concepts and methodology set forth in this book to be applied to socio-economic systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book is a pedagogical introduction to supergravity, a gravitational field theory that includes supersymmetry (symmetry between bosons and fermions) and is a generalization of Einstein's general relativity. Supergravity provides a low-energy effective theory of superstring theory, which has attracted much attention as a candidate for the unified theory of fundamental particles, and it is a useful tool for studying non-perturbative properties of superstring theory such as D-branes and string duality.This work considers classical supergravities in four and higher spacetime dimensions with their applications to superstring theory in mind. More concretely, it discusses classical Lagrangians (or field equations) and symmetry properties of supergravities. Besides local symmetries, supergravities often have global non-compact symmetries, which play a crucial role in their applications to superstring theory. One of the main features of this book is its detailed discussion of these non-compact symmetries.The aim of the book is twofold. One is to explain the basic ideas of supergravity to those who are not familiar with it. Toward that end, the discussions are made both pedagogical and concrete by stating equations explicitly. The other is to collect relevant formulae in one place so as to be useful for applications to string theory.The subjects discussed in this book include the vielbein formulation of gravity, supergravities in four dimensions, possible types of spinors in various dimensions, superalgebras and supermultiplets, non-linear sigma models for non-compact Lie groups, electric-magnetic duality symmetries, supergravities in higher dimensions, dimensional reductions, and gauged and massive supergravities.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 140 pp. Englisch.

Buch. Condizione: Neu. Neuware -By providing a comprehensive overview of policy proposals for the international monetary system from an Asian perspective, this book aims to identify what innovations are needed to reform the international monetary and financial system to promote financial stability and sustainable economic growth for emerging economies. The book is organized into four parts. Part 1 discusses major theoretical and empirical issues related to reform of the international monetary system. Part 2 includes two chapters that present the recent developments and challenges for managing capital flows. Part 3 presents different perspectives on regional currency cooperation in Asia and Europe by assessing the evidence supporting increased currency coordination in Asia and by review issues of policy cooperation in the Euro area after the global financial crisis and their implications for Asia. Part 4 discusses emerging issues for regional/global cooperation and financial safety nets. The main inference of the book is that, in light of the drawbacks of the existing international monetary system exposed in the global financial crisis, along with other countries, Asian emerging economies should work cooperatively to reform and strengthen international monetary and financial policy. To do so, regional and global monetary cooperation is needed and financial safety nets should be strengthened to alleviate the impact of possible global financial crises. This will be one of the first books written about the global financial crisis and the on going the European sovereign debt crisis to comprehensively address the issues related to currency cooperation, based on the Euro area experience, with the specific implications for Asia.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book focuses on the development of liquid crystal displays (LCDs) and liquid crystal materials (LCs) in Japan. The Committee of Organic Materials Research for Information Sciences of the Japan Society for the Promotion of Science (JSPS) planned the book to document essential LCD innovations and developments since the beginnings of the field-effect LCD technology in 1970. The book illustrates the remarkable effort and progress behind those flat, lightweight, and high-information-content LCDs that have become the indispensable human¿machine interface for virtually all electronic devices. In contrast to other publications on this topic, the book illustrates the interdisciplinary character of the LCD technology and its crucial importance for technological progress of the field far beyond displays. It also gives insights into breakthrough innovations not revealed in other publications. Moreover, prospects for the development of LC research toward new fields of applications are provided. In line with its interdisciplinary character, the book targets researchers in basic science as well as engineers and researchers in industry.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 432 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book presents an overview of current knowledge about social¿ecological systems (SESs), a productive new field dedicated to understanding the relationships between human society and nature. To make the reader aware of how SESs are necessary to maintain our society, the book begins with a broad perspective about what social¿ecological systems are and what the related research issues in this field are as well. The second part discusses how human activities have changed ecosystems from temperate grasslands to tropical areas. The third part focuses on the adaptability of societies to unpredictable fluctuation in ecosystems, while the last part summarizes factors for the resilience of society against social and ecological shocks. Human activities have severely degraded most natural ecosystems, which are now in critical condition. Various approaches have been developed to improve the SESs, to understand environmental problems and explore better ways to increase the sustainability both of ecosystems and of human societies. However, a clear perspective on how to address such problems is still lacking. Part of the difficulty arises because of the diversity and complexity of ecosystems and human societies. Another important factor is the effect of extremely rapid changes in the social and economic characteristics of social¿ecological systems. Consequently, adaptability and resilience clearly are essential for the sustainability of SESs. Although there is no one, direct method to achieve high adaptability and resilience, a possible way is to compare and understand the diverse problems associated with differing social¿ecological systems. This published work makes a useful contribution to a greater understanding of the way that essential social responses linked to changes in ecosystems can potentially stimulate further research on this important and interesting subject. The book will attract the attention of scholars in environmental sciences, ecology, andsociology, and indeed of anyone interested in the concept of social¿ecological systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 212 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book examines social and natural environmental changes in present-day Laos and presents a new research framework for environmental studies from an interdisciplinary point of view. In Laos, after the Lao version of perestroika, Chintanakaan Mai, in 1986, for better or worse, rural development and urbanization have progressed, and people¿s livelihoods are about to change significantly. Compared to those of the neighboring countries of mainland Southeast Asia, however, many traditional livelihoods such as region-specific/ethnic-specific livelihood complexes, which combined traditional rice farming with a variety of subsistence activities, have been carried over into the present in Laos. The biggest challenge this book presents is to elucidate livelihood strategies of people who cope successfully with both social and environmental changes and to illustrate how to maintain this rich social and natural environment of Laos in the future. The book includes chapters on social, cultural, and natural concerns and on ethnicity, urbanization, and regional development in Laos. All chapters are based on original data from field surveys. These data will greatly contribute not only to local studies in Laos but also to environmental studies in developing countries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book covers an approach to conversational informatics which encompasses science and technology for understanding and augmenting conversation in the network age. A major challenge in engineering is to develop a technology for conveying not just messages but also underlying wisdom. Relevant theories and practices in cognitive linguistics and communication science, as well as techniques developed in computational linguistics and artificial intelligence, are discussed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book will be of interest to scholars and students of Asian studies, cultural industries, economic geography, and related areas of study. It discusses the results of a microscopic survey focusing on topics such as how animation studios form business relationships and how workers gain skills in the industry. The methodology was based on traditional Japanese economic geographical methods. The study also examines macroscopic issues such as why industrial agglomerations are formed in metropolises, why metropolises develop mutual networks, and how a type of cultural product is created in the metropolises. The methodology uses case studies of the animation industries in Japan, South Korea, and China. The detailed analysis covers the process of the industry¿s agglomeration within the East Asian metropolises of Tokyo, Seoul, and Shanghai as well as the division of labor among them. In addition, the transaction relationships among animation studios are examined, together with the promotion of the industry in the peripheral region of Okinawa, Japan. Differences in work styles and output among these cities are also examined. The research presented in this book contributes to understanding the spatial structure and reality of creativity inan innovative industry, particularly the East Asian content industry.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 164 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book highlights recent advances in natural computing, including biology and its theory, bio-inspired computing, computational aesthetics, computational models and theories, computing with natural media, philosophy of natural computing and educational technology. It presents extended versions of the best papers selected from the symposium ¿7th International Workshop on Natural Computing¿ (IWNC7), held in Tokyo, Japan, in 2013.The target audience is not limited to researchers working in natural computing but also those active in biological engineering, fine/media art design, aesthetics and philosophy.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 140 pp. Englisch.

Buch. Condizione: Neu. Neuware -Education for Sustainable Development (ESD) and Disaster Risk Reduction Education (DRRE) have overlapping areas of concern focusing on strengthening the link to local communities. In reality, there is significant synergy in ESD and disaster risk reduction (DRR). Both concepts urge looking at the communities, both focus on behavior changes and both call for linking knowledge to action. The Decade of Education for Sustainable Development (DESD) ends in 2014 and the Hyogo Framework for Action (HFA) ends in 2015. Therefore, at this junction, it is important to review the progress made over the past 10 years and to suggest future synergy options. This book is the first attempt to review these two emerging fields and to provide input to the future direction of education.The book has 11 chapters, drawing lessons mainly from Japan and discussing their implications for the world. The first four chapters provide an overview of the ESD¿DRR linkage, ESD and its evolution, DRRE and Climate Change Education. These are followed by case studies from ESD practices in Japan, in schools, universities and communities.The primary target groups for this book are students and researchers in the fields of environment, disaster risk reduction and climate change studies. The book provides them with a good idea of the current research trends in the field and furnishes basic knowledge about these vital topics. Another target group comprises practitioners and policy makers, who will be able to apply the knowledge collected here to establishing policy and making decisions.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 200 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -More than seven years have passed since the dramatic breakthrough in the critical temperature for superconductors. During this period, a host of new materials have been discovered, and efforts have been stepped up in a variety of domains including device and systems applications, commercialization, and basic research on the properties of superconductive materials. Recent progress in areas such as bulk single crystal production, long-scale wire and tape produc tion, flywheel and bearing applications, and electronic device applications for thin films indicate that science and technology have been working hand in hand in this field, as has been the case in the research and development of semi conductors. This interdisciplinary 'resonance' will be certain to lead to further outstanding advances in the years to come. It goes without saying that worldwide information exchange is the key to accelerating progress in superconductivity science and technology. As in previous years, the ISS '93 served as a venue where visions of future develop ments were shared in addition to presentations and extensive discussions on the most up-to-date research results. I hope that the Proceedings contained in this volume will be consulted not only as a summary of the current 'state of the art' in high-Tc superconductivity but also as a stimulating source of ideas regarding future applications of superconductivity research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1448 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -'Phonosurgery: theory and practice' is a book that makes an impor tant contribution to the literature in laryngology. Professor Isshiki has been a driving force in the investigation and correction of certain conditions of the voice. His leadership in this field over two decades has proved to be an inspiration to those interested in the diagnosis and correction of the abnormal voice. His unique background and training in both otolaryngology and plastic surgery has provided him with fundamental knowledge and experience in the study of the voice and larynx and has given him an opportunity to utilize innovative surgical techniques in the correction of some of these problems. Professor Isshiki's name is indelibly linked with laryngeal framework surgery, and those who read this book will not be dis appointed. The book provides very adequate information on the phy siology and pathology of the voice. Emphasis is given to diagnostic aspects of abnormalities of the voice which have been made easier with the development of high technology, such as the use of the com puter and improved laryngoscopes, which include brighter lights, higher resolution lenses, and, when combined with stroboscopy and high-speed filming videolaryngoscopy, provide a valuable tool in faci litating communication between the patient, the physician, and the voice therapist.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book examines current trends and developments in the methods and applications of geospatial analysis and highlights future development prospects. It provides a comprehensive discussion of remote sensing- and geographical information system (GIS)-based data processing techniques, current practices, theories, models, and applications of geospatial analysis. Data acquisition and processing techniques such as remote sensing image selections, classifications, accuracy assessments, models of GIS data, and spatial modeling processes are the focus of the first part of the book. In the second part, theories and methods related to fuzzy sets, spatial weights and prominence, geographically weighted regression, weight of evidence, Markov-cellular automata, artificial neural network, agent-based simulation, multi-criteria evaluation, analytic hierarchy process, and a GIS network model are included. Part three presents selected best practices in geospatial analysis. The chapters, all by expert authors, are arranged so that readers who are new to the field will gain an overview and important insights. Those readers who are already practitioners will gain from the advanced and updated materials and state-of-the-art developments in geospatial analysis.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The 11th International Symposium on Superconductivity was held November 16-19, 1998, in Fukuoka, Japan. Convened annually since 1988, the symposium covers the whole field of superconductivity from fundamental physics and chemistry to new applications. At the 11th Symposium, there was increased interest reported in the development of trial devices using bismuth wires and yttrium-based bulk materials. Among the presentations were those that clearly defined the development targets for next-generation yttrium-based wires and bulk materials and single-flux quantum (SFQ) circuits. Other popular topics were high-temperature superconductivity applications such as SQUIDs, microwave filters, and cryocooler-cooled magnets. With more than 600 participants from 18 countries, the symposium provided an excellent forum for exchanges of the most recent information in the field of superconductivity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1624 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book is a collection of papers presented at the Forum ¿The Impact of Applications on Mathematics¿ in October 2013. It describes an appropriate framework in which to highlight how real-world problems, over the centuries and today, have influenced and are influencing the development of mathematics and thereby, how mathematics is reshaped, in order to advance mathematics and its application. The contents of this book address productive and successful interaction between industry and mathematicians, as well as the cross-fertilization and collaboration that result when mathematics is involved with the advancement of science and technology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 388 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book focuses on the two psychological factors of naturalness and ease of viewing of three-dimensional high-definition television (3D HDTV) images. It has been said that distortions peculiar to stereoscopic images, such as the ¿puppet theater¿ effect or the ¿cardboard¿ effect, spoil the sense of presence. Whereas many earlier studies have focused on geometrical calculations about these distortions, this book instead describes the relationship between the naturalness of reproduced 3D HDTV images and the nonlinearity of depthwise reproduction. The ease of viewing of each scene is regarded as one of the causal factors of visual fatigue. Many of the earlier studies have been concerned with the accurate extraction of local parallax; however, this book describes the typical spatiotemporal distribution of parallax in 3D images. The purpose of the book is to examine the correlations between the psychological factors and amount of characteristics of parallax distribution in order to understand the characteristics of easy- and difficult-to-view images and then to seek to create a new 3D HDTV system that minimizes visual fatigue for the viewer. The book is an important resource for researchers who wish to investigate and better understand various psychological effects caused by stereoscopic images.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 136 pp. Englisch.

Buch. Condizione: Neu. Neuware -The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments. The book depicts the mechanisms that underlie inner ear diseases, their experimental models, and proposals for new strategies to treat their symptoms. As well, the exciting future prospects for dealing with the very common problem of inner ear diseases are explained. These disorders occur among many people and include sensorineural hearing loss (SNHL), sudden deafness, senile deafness, noise-induced deafness, tinnitus, dizziness¿vertigo, and Ménière¿s disease. In Japan alone, there are more than 6 million deaf patients including those with middle-range deafness. There is currently no effective treatment, and regardless of the underlying cause, the damage has been considered irreversible. However, the results of recent research show that these patients actually can recover. The study of hair cells, spiral ganglion neurons, and stem cells for inner ear diseases such as SNHL, tinnitus, dizziness, and vertigo is at the forefront of regenerative medicine and may provide solutions to some of these problems. The information presented here makes this book a valuable professional reference work for all doctors and researchers in the field of otolaryngology who focus on regenerative treatments for inner ear diseases.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book reviews a variety of methods for wave-based acoustic simulation and recent applications to architectural and environmental acoustic problems.Following an introduction providing an overview of computational simulation of sound environment, the book is in two parts: four chapters on methods and four chapters on applications. The first part explains the fundamentals and advanced techniques for three popular methods, namely, the finite-difference time-domain method, the finite element method, and the boundary element method, as well as alternative time-domain methods. The second part demonstrates various applications to room acoustics simulation, noise propagation simulation, acoustic property simulation for building components, and auralization.This book is a valuable reference that covers the state of the art in computational simulation for architectural and environmental acoustics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 340 pp. Englisch.

Buch. Condizione: Neu. Neuware -Endometriosis is one of the most common gynecological diseases, causingpelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it.This book provides a clear insight intothe pathogenesis and pathophysiology of endometriosis¿essentialinformation forcliniciansintending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 488 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The selected papers included in this proceedings on Malaysia-Japan Academic Scholar Conference (MJASC) 2013, are related to nano-science engineering, mechanical engineering, electrical and electronic engineering, computer science, information technology etc. This proceedings will be a source of research findings for Malaysia and Japan specifically, and other countries in general, especially among researchers, industry sectors and government policy makers. Itwill be served as a resourceful reference and platform to reflect the significant of the Look East Policy outcomes and products.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve.With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells.This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 368 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The International Symposium on Superconductivity, which has been held annu ally since 1988, is a forum for presenting the most up-to-date information about a broad range of research and development in superconductivity, from funda mental aspects to applications. More than 10 years have passed since the discovery of oxide superconductors and since various developments of applications began. It may be said that the prospects for application of oxide superconductors recently have opened up. Great progress has been made toward practical use, for example, of the flywheel, which uses bulk materials, and the high-performance cryo-cooled magnet made of bismuth wire. These were the results of persistent efforts to develop materials from the viewpoint of materials science and engineering. Also important is the progress in comprehensive understanding of high temperature superconductivity. Unique electronic properties of cuprates such as the non-Fermi liquid normal state, spin-charge separation, spin gap, and d-wave symmetry were discussed at the symposium, as were the unique electromagnetic properties resulting from the low dimensionality of cuprates. In the field of new superconductors, many exotic materials have been discovered since 1986. A decade of work with cuprate superconductors is reviewed in this proceedings, and several of the newest materials are presented. These papers will be instructive for many researchers and for students who are to enter this field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1540 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Since the discovery of superconductivity with trans1tton temperatures above 77 K, concentrated research activities toward the exploration of practical applica tions of these materials have been carried out. Currently, a remarkable improve ment in superconducting properties has been achieved due to the fine optimization of fabrication processes, and this has attracted industrial interest for future applications. In the case of NdBa Cu 0 materials, a new pinning mecha 2 3 7 nism was found which enhances the critical current under applied magnetic fields. In single crystals of these materials, oxygen control results in an increase in the growth rate. The metalorganic chemical vapor deposition (MOCVD) film quality has been improved by using a new liquid raw material. Simultaneously, real demands from the viewpoint of the market start to be a motivation force, es pecially in electronics application where some products are already being sold. At the same time, interesting physical properlies have been obtained from a new superconducting single crystal which has a layered perovskite structure without copper. In addition, various precision measurement techniques have confirmed the d-wave mechanism and the existence of intrinsicJosephson junctions in single crystals. These new phenomena challenge the existing theoretical models but also open the way for new applications. These significant areas of progress in materials science have led high-Tc super conductivity research into the next phase of activity, while fundamental research continues to be very important. I sincerely hope that this volume will give further impetus to this development.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 1452 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -At the Fifth International Neuromuscular Meeting held in Tokyo in 1994, leading experts in the field came together to discuss the physiology and pharmacology of neuromuscular receptor sites and neuromuscular blocking agents (NBAs). The proceedings of the meeting present a review of the history of muscle relaxants and a comprehensive examination of recent research, with a primary focus on clinical considerations. Among the topics covered by specific chapters are aspects of the neuromuscular junction (NMJ), pharmacokinetics, metabolism and metabolites of neuromuscular blocking agents, and drug interaction. Presenting the most up-to-date knowledge of the physiology and pharmacology of the NMJ and NBAs, this volume will be highly valuable to clinicians and researchers in anesthesiology, physiology, and pharmacology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In macro-econometrics more attention needs to be paid to the relationships among deterministic trends of different variables, or co-trending, especially when economic growth is of concern. The number of relationships, i.e., the co-trending rank, plays an important role in evaluating the veracity of propositions, particularly relating to the Japanese economic growth in view of the structural changes involved within it. This book demonstrates how to determine the co-trending rank from a given set of time series data for different variables. At the same time, the method determines how many of the co-trending relations also represent cointegrations. This enables us to perform statistical inference on the parameters of relations among the deterministic trends. Co-trending is an important contribution to the fields of econometric methods, macroeconomics, and time series analyses. 128 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This thesis presents the first report of the comprehensive and quantitative analysis of the effects of tumor-derived mutations on the tetrameric structure of tumor suppressor protein p53, which plays a central role in maintaining genomic integrity. Inactivation of p53 via mutation of its gene is a key step in tumorigenesis. Biophysical analyses revealed that the stability of the mutant peptides varied widely. Formation of a tetrameric structure is to be critical for protein-protein interactions, DNA binding, and the post-translational modification of p53. A small destabilization of the tetrameric structure therefore could result in dysfunction of tumor suppressor activity. This work suggests that the threshold for loss of tumor suppressor activity, in terms of the disruption of p53's tetrameric structure, could be extremely low. Furthermore, functional control of p53 via tetramer formation was demonstrated, based on the structure-function analysis of mutant p53. The results disclosed that relatively small changes in tetramer formation, induced by the stabilization or inhibition of homo-tetramerization, could control p53 function. 88 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A lot of economic problems can be formulated as constrained optimizations and equilibration of their solutions. Various mathematical theories have been supplying economists with indispensable machineries for these problems arising in economic theory. Conversely, mathematicians have been stimulated by various mathematical difficulties raised by economic theories. The series is designed to bring together those mathematicians who are seriously interested in getting new challenging stimuli from economic theories with those economists who are seeking effective mathematical tools for their research. 144 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Hepatocellular carcinoma is one of the most common fatal malignan cies of mankind. Up to a few decades ago it was looked upon as a cancer which aroused mainly academic concern but relatively little clinical interest, because its therapy and prognosis had a most un favorable outlook. Indeed, it was mostly recognized only at autopsy. Recently this pessimism has radically changed and is disappearing to a rapidly accelerating degree. Many of the scientific contributions at this change in outlook are the result of research in the Far East, first, Japan and then gradually extending to its neighbors. The introduction of experimental hepatocarcinogens by Yoshida more than 50 years ago may have been one of the first important steps. Hepatocellular car cinoma shows a characteristic geographical distribution. With the highest incidence in China, Taiwan, Southeast Asia and sub-Saharan Africa, followed by southern and eastern Europe, while generally the incidence is rather low in western and northern Europe and North and South America.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 280 pp. Englisch.