Springer london nov 2011 (90 risultati)

Taschenbuch. Condizione: Neu. Neuware -This book discusses the use of the real numbers in theorem proving. Typ ically, theorem provers only support a few 'discrete' datatypes such as the natural numbers. However the availability of the real numbers opens up many interesting and important application areas, such as the verification of float ing point hardware and hybrid systems. It also allows the formalization of many more branches of classical mathematics, which is particularly relevant for attempts to inject more rigour into computer algebra systems. Our work is conducted in a version of the HOL theorem prover. We de scribe the rigorous definitional construction of the real numbers, using a new version of Cantor's method, and the formalization of a significant portion of real analysis. We also describe an advanced derived decision procedure for the 'Tarski subset' of real algebra as well as some more modest but practically useful tools for automating explicit calculations and routine linear arithmetic reasoning. Finally, we consider in more detail two interesting application areas. We discuss the desirability of combining the rigour of theorem provers with the power and convenience of computer algebra systems, and explain a method we have used in practice to achieve this. We then move on to the verification of floating point hardware. After a careful discussion of possible correctness specifications, we report on two case studies, one involving a transcendental function.…

Taschenbuch. Condizione: Neu. Neuware - This book discusses the use of the real numbers in theorem proving. Typ ically, theorem provers only support a few 'discrete' datatypes such as the natural numbers. However the availability of the real numbers opens up many interesting and important application areas, such as the verification of float ing point hardware and hybrid systems. It also allows the formalization of many more branches of classical mathematics, which is particularly relevant for attempts to inject more rigour into computer algebra systems. Our work is conducted in a version of the HOL theorem prover. We de scribe the rigorous definitional construction of the real numbers, using a new version of Cantor's method, and the formalization of a significant portion of real analysis. We also describe an advanced derived decision procedure for the 'Tarski subset' of real algebra as well as some more modest but practically useful tools for automating explicit calculations and routine linear arithmetic reasoning. Finally, we consider in more detail two interesting application areas. We discuss the desirability of combining the rigour of theorem provers with the power and convenience of computer algebra systems, and explain a method we have used in practice to achieve this. We then move on to the verification of floating point hardware. After a careful discussion of possible correctness specifications, we report on two case studies, one involving a transcendental function.…

Taschenbuch. Condizione: Neu. Neuware - The publication of Platelet-Vessel Wall Interactions, the second monograph in the Bloomsbury Series in Clinical Science, is particu larly welcome as its appearance signifies the further development of the Series and its potential for the future. The theme of this monograph is the pathophysiology of atherosclerosis, a topic that symbolises the aim of the Series, namely to highlight the important interfaces between basic medical science and clinical practice. Our congratulations to the Editors and contributors. London, December 1987 lack Tinker Preface In the Western world, atherosclerosis causes more illness and death than any other disease. Despite its devastating effects, the pathogenesis of the disease remains a matter for hypothesis and con jecture. This monograph owes its conception to a programme of work directed towards understanding the basic pathophysiology of atherosclerosis. The circulatory system is lined by vascular endothelium which has a central role in maintaining the integrity of the vessel wall and prevent ing thrombosis. The natural equilibrium existing between normal en dothelium which supports blood flow, and platelets which serve to re pair damaged endothelium, is explored in the first two chapters. Atherosclerosis developing as a response to endothelial injury is one hypothesis which has stimulated widespread interest, and re search has largely been directed towards finding the injurious agent.…

Taschenbuch. Condizione: Neu. Neuware -This book discusses the use of the real numbers in theorem proving. Typ ically, theorem provers only support a few 'discrete' datatypes such as the natural numbers. However the availability of the real numbers opens up many interesting and important application areas, such as the verification of float ing point hardware and hybrid systems. It also allows the formalization of many more branches of classical mathematics, which is particularly relevant for attempts to inject more rigour into computer algebra systems. Our work is conducted in a version of the HOL theorem prover. We de scribe the rigorous definitional construction of the real numbers, using a new version of Cantor's method, and the formalization of a significant portion of real analysis. We also describe an advanced derived decision procedure for the 'Tarski subset' of real algebra as well as some more modest but practically useful tools for automating explicit calculations and routine linear arithmetic reasoning. Finally, we consider in more detail two interesting application areas. We discuss the desirability of combining the rigour of theorem provers with the power and convenience of computer algebra systems, and explain a method we have used in practice to achieve this. We then move on to the verification of floating point hardware. After a careful discussion of possible correctness specifications, we report on two case studies, one involving a transcendental function. 200 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dr. Tuttlebee is the editor of the popular Cordless Communication in Europe, and works at Roke Manor - a division of Siemens. Here, he includes significant new material drawn from contributions by major manufacturers, consultants and research laboratories, such as Ericsson, Olivetti, Philips, Northern telecom, Hutchinson, TRT and PA Consulting.The result is a global overview of the state of the art, with a detailed look at the applications, markets and standards as they have developed and continue to do so. Provides an essential technical summary for all those considering entering this challenging field or those managing existing operations. 564 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With national trade barriers falling, causing the expansion of the com petitive global market, the question of quality control has become an essential issue for the 1990s. The time where the promise was to replace a product if it does not work seems to have passed; what is more impor tant now is not so much a reduction in what is going wrong but an increase of what is going right the first time (Feigenbaum 1990). This new trend is sometimes referred to as total quality. Among the many advantages ofthis zero-defect manufacturing policy, we can enumerate (Laurin 1990): superior marketability of wholly de pendable products, enormous gain in productivity, elimination of waste ful cost in replacing poor quality work and retrofitting rejected products from the field. Although total quality is a relatively new and attractive concept for mass products such as cars, consumer electronics and per sonal computers, in many fields, mainly aerospace and military, it has been the rule for years because of security reasons. 244 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the last decade the therapeutic approach to musculoskeletal tumors has changed dramatically, from ablative surgery with ampu tation ofthe limb to reconstructive surgery with transplantation of bone and vessels combined with radio-and chemotherapy. This has changed the demands on radiologists and pathologists to a considerable degree. At the same time there has been a manifold increase in the diagnostic possibilities offered by modern radiology, with several new modalities affording a potential for morphologic depiction and tissue character ization that was unattainable a decade ago. Today, the definitive diagnostic work-up and treatment of patients with musculoskeletal tumors is most often done in tumor centers, by groups that ideally should be composed of an orthopedic surgeon, radiotherapist, oncologist, radiologist, pathologist and cytologist. It is necessary for all the members of this team to be well versed in the surgi cal and other treatment principles, in the pathologic concepts, and in the radiologic interpretation of musculoskeletal tumors. Moreover, it is important that the modern diagnostic approach to musculoskeletal tumors is well known also at the referring center, be it a private practi tioner's office or a large hospital. This will avoid unnecessary biopsies, and repetition of radiologic and other diagnostic procedures that have already been performed at the referring center. 168 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Major epidemiologists from the UK, USA and Europe contributeto the first ever, much needed comprehensive review of theepidemiology of peripheral vascular disease in the lowerlimbs. 392 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In their preface, the authors highlight the great social and medical importance of hearing loss in the elderly, an ever-increasing prob lem. It is, therefore, most appropriate that a monograph, devoted to research in this field, features as an addition to the Bloomsbury Series in Clinical Science. Written by two leading authorities, the book reviews the past and present literature, details the clinical aspects and considers the electrophysiological and histopatho logical issues basic to the overall problem. It continues the high standard and excellence fostered by previous issues in the Series. London, August 1990 Jack Tinker Preface The number of very old people in the community is steadily increasing so the hearing loss that many of them endure has become a disorder of social and medical importance. Only by a greater scientific knowledge of old age deafness can there be any possibility for improvement in the care offered to its sufferers. 132 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A variety of new techniques that promise to revolutionize the clinical management of early pregnancy are fully detailed in this state-of-the-art book. Leading international researchers describe fast-moving topics such as embryo manipulation and the diagnosis of congenital abnormalities. The technology of assisted reproduction has made it possible to study living embryonic material for the first time, which has led to rapid advances in our understanding of the human embryo's early development. For example, study of the embryo in the test tube has pointed to early pregnancy loss as a possible cause of later infertility. Even more important, diagnostic tests using sophisticated techniques of molecular biology can be run on single cells before the embryo is replaced in the uterus. Another area of advance is the diagnosis of congenital abnormalities in the first and second trimesters of pregnancy. Great improvements have been made in the techniques of chorion villus biopsy and ultrasound imaging. A spectrum of simple biochemical tests performed on the mother's blood can greatly improve the detection of Down syndrome and other chromosome defects. Together with other developments in the fields of molecular biology and endocrinology, these new diagnostic techniques are the beginning of a new age in clinical human genetics and embryology. 280 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -What medicine lacks in an increasingly specialised world is the medical polymath (or should it be medical bimath ) - the man who is an acknowledged expert in more than one field of medicine. Superpecialisation in the professional sense is an attempt to know more and more about less and less. It can be the microscopist's view of reality and such a microcosm can become also a refuge from realities. One reality difficult for the very specialised doctor to accept is that diseases don't exist. Only people with diseases exist and people do not always conform to convenient categories and compartments. It would be nice if they did but somehow they never do. A cherished medical tradition in Britain is that specialists are not hatched straight from medical schools. Indeed, young doctors are actively discouraged from taking too narrow an interest but are plunged for at least four years into the unspecific pool of general medicine until they have developed a broad awareness of the totality of human disease. Before this they are not allowed to narrow their sights on one particular target. 268 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents an objective state-of-the-art synopsis of the sucrose literature. Of its two main sections one is monographic and covers topics such as chemical and physical data on sucrose and its two major components (glucose and fructose), production, use, occurrence, metabolism and kinetics in animals and man, biochemical, health and safety aspects. The second section contains a bibliography of virtually all the significant works relating to the nutritional and safety aspects of sucrose. 216 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -possibly neoplastic, some not. In essence, the Often enough, in diagnosing cancer the last word rests with the pathologist and his or her micro book is concerned with interpretation of the scope. Often enough, too, the pathologist is borderline or histologically equivocal case and thought to dispense absolute truth: he does his the clinical implications thereof. It is based on best, but the truth he dispenses is not absolute. so me 390 examples of which most are individu Rather, with a greater or lesser degree of con ally described in brief. No useful purpose is fidence, he is making aprediction or expressing served by giving in detail the clinical and patho a prob ability of a certain kind of biological logical circumstances of every patient with, say, behaviour, and the degree of confidence with a dubious lesion of endometrium or larynx, or which he operates is based on experience. This with a similarly borderline papilloma in bladder experience is, in turn, based on the recollection or rectum, for each of these lesions exemplifies of earlier events, counsel from his mentors, from a familiar and 'standard' problem. Problems of his studies, and from discussions with colleagues. this kind will be examined as such but not the It would be going too far to agree with those details of every patient who posed them. 488 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Manual flight control system design for fighter aircraft is one of the most demanding problems in automatic control. Fighter aircraft dynamics generally have highly coupled uncertain and nonlinear dynamics. Multivariable control design techniques offer a solution to this problem. Robust Multivariable Flight Control provides the background, theory and examples for full envelope manual flight control system design. It gives a versatile framework for the application of advanced multivariable control theory to aircraft control problems. Two design case studies are presented for the manual flight control of lateral/directional axes of the VISTA-F-16 test vehicle and an F-18 trust vectoring system. They demonstrate the interplay between theory and the physical features of the systems. 180 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -If a substance is repeatedly subdivided, the result is what are known as 'microscopic particles'. These particles are distinguished from the solid mass which they originally formed by the size of the surface area per unit weight. This simple difference holds true down to a certain lower size limit, and when this limit is exceeded, a new state of matter is reached, in which the behavior of the particles is quite different to that of the original solid. Particles in this state are termed 'superfine particles', and are distinct from ordinary particles. The size of the superfine particles, that is to say the size limit below which particle behavior is completely different from the behavior of the original solid, varies a good deal depending on the physical properties of the substance in question. Properties such as magnetism and electrical resistance are closely related to the internal structural properties of the particles themselves, such as the magnetization processes of their respective magnetic domains, and the mean free path of charged bodies. This internal structure therefore limits the size of the superfine particles. In ceramic processing, on the other hand, the surface area of the particles themselves becomes an even more important factor than their internal structure. In this case, the size of the superfine particles is determined by the interaction between water and solvents on the surface of the particles. 236 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The series Advances in Industrial Control aims to report and encourage technology transfer in control engineering. The rapid development of control technology impacts all areas of the control discipline. New theory, new controllers, actuators, sensors, new industrial processes, computing methods, applications, philosophies, . . . , new challenges. Much of this development work resides in industrial reports, feasibility study papers and the reports of advanced collaborative projects. The series offers an opportunity for researchers to present an extended exposition of such new work in all aspects of industrial control for wider and rapid dissemination. The autotune method of Astrom and Hagglund had a major impact on the hardware and structure of PID process controllers. However, despite a substantial body of theoretical analysis, progress in transferring the benefits of more general self-tuning methods to industrial devices and processes has been much slower. This volume by Dr's Stephan and Keuchel shows that this type of technology transfer can be achieved and that the more advanced adaptive controllers do give performance benefits over conventional industrial (three term) controllers. The volume also shows the requirements in hardware, the need for software skills and the engineering techniques required to achieve satisfactory results. We hope that by recording their engineering know-how more researchers and industrialists will be encouraged to tap the benefits of advanced self-tuning and adaptive control methods. July, 1993 Michael J. Grimble and M. A. Johnson, Industrial Control Centre, Glasgow, Scotland, U. K. 172 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Malignant brain tumours remain a not uncommon cause of disability and premature death, particularly in children and middle-aged adults. This is only too weIl known by those con cerned with the dinical management of such patients. Thus, not onlyare malignant cerebral gliomas very aggressive tumours, usually associated with a rapidly fatal outcome, but also it has been recognised more recently that low grade gliomas often have a poor prognosis. Furthermore, the increased application of non-invasive neuroradiological imaging to patients with other types of tumour has disdosed an even larger number of metastatic brain tumours than has been recognised previously. In the last decade, the spectrum of malignant brain tumours has been further widened by the ons et of tumours related to acquired immunodeficiency syndrome (AIDS). Nevertheless, all is not gloom, and within the community of life-science profes sionals in the neuro-oncological specialities, both scientific and dinicaI, there is some optimism that matters, albeit slowly, will change for the better. This hope is based largely on the realis ation that large amounts of pertinent information exist about the biology of these tumours at molecular and cellular levels. It is also based on the ability to image them by eT and MR methods, often at an early stage in the disease, as well as on the capacity to achieve accurate histopathological correlation with the diagnostic imaging. Thus, the necessary prerequisites for the optimum treatment of these diseases by surgery, by radiation, and by drug treatment exist. 420 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The introduction of prostaglandins into clinical practice has been one of the most important advances in obstetrics and gynaecology in recent years. During the last decade obstetricians have become familiar with these drugs for inducing labour and for terminating second-trimester pregnancy. Within the last year their use has been extended, in association with antiprogestin, to first-trimester termi nation. Although the effectiveness of prostaglandins in these pharma cological roles is clear, their full potential has still to be explored, and much remains to be learned about their physiology. Prostaglandins playa central role in the initiation of labour. Further clarification of this role could lead to improvements in preventing or treating preterm labour, which still remains the most important cause of perinatal mortality in this country. Prostaglandins are also inti mately involved in the mechanism of menstruation. More detailed understanding of this role should lead to more effective treatments for menorrhagia and dysmenorrhoea. These substances also playa part in the mechanism of implantation, and further research in this area may lead to more effective therapy for infertility. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In vitro fertilization has resulted in an estimated 4000-5000 births in the world. The procedure has been accepted in Europe, America and Australia and several hundred IVF clinics are operating successfully. The newer procedures of GIFf, embryo freezing and donor oocyte IVF have become established and are dealt with in several chapters. GIFf has become the procedure of choice for patients with infertility of unknown origin. Oocyte freezing represents an important new technology which is being developed. The routine IVF procedure has improved slightly; variation in results can be reduced by quality control of laboratory and clinical techniques. Male factor infertility has been dealt with by IVF in mild and moderate cases, but newer techniques will be required to deal with severe problems in the male. Most countries have accepted that the straightforward IVF pro cedure is ethical. Limitations concerning the use of donor oocytes and embryo experimentation exist in some religions and countries; legal control of the new reproductive technologies ranges from the passage of statutes to no control at all. Many countries are still considering the need for legislative control. The text endeavours to indicate new areas of importance and to guide those organizing services as to how to introduce newer technolo gies. 188 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Infertility, as with many aspects of medicine, is at the mercy of rapid technological advance. Many of these developments initially seem attractive to both clinicians and patients, but need to be rigorously assessed if their real value is to be understood and clinical practice is to develop. In this book issues of importance to the management of infertile patients are discussed. The gaps in our knowledge which prevent a better understanding of the condition are identified, and recent developments, both clinical and scientific, are subjected to peer review and discussion. An important feature of the book is an acceptance that training in infertility practice is a real problem. This is perceived not only by the practising clinicians, both doctors and nurses, but particularly by the clinical scientists, including embryologists, who now provide such an essential part of the service. Similarly the provision of the clinical service has been examined in detail from a variety of standpoints, in an attempt to make sensible recommendations which balance real need with limited resource. The book is based on the papers presented and discussed at the 25th RCOG Study Group held in April 1992. The discussion after each paper was civilised but uncompromising and forms an important part of this publication. The rapid processing of the written and recorded material by the staff at the RCOG, and particularly Miss Sally Barber, has ensured that the book has been produced while the issues are live, the reviews contemporary and the discussion relevant. 448 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The most important invariant of a topological space is its fundamental group. When this is trivial, the resulting homotopy theory is well researched and familiar. In the general case, however, homotopy theory over nontrivial fundamental groups is much more problematic and far less well understood. Syzygies and Homotopy Theory explores the problem of nonsimply connected homotopy in the first nontrivial cases and presents, for the first time, a systematic rehabilitation of Hilbert's method of syzygies in the context of non-simply connected homotopy theory. The first part of the book is theoretical, formulated to allow a general finitely presented group as a fundamental group. The innovation here is to regard syzygies as stable modules rather than minimal modules. Inevitably this forces a reconsideration of the problems of noncancellation; these are confronted in the second, practical, part of the book. In particular, the second part of the book considers how the theory works out in detail for the specific examples Fn F where Fn is a free group of rank n and F is finite. Another innovation is to parametrize the first syzygy in terms of the more familiar class of stably free modules. Furthermore, detailed description of these stably free modules is effected by a suitable modification of the method of Milnor squares. The theory developed within this book has potential applications in various branches of algebra, including homological algebra, ring theory and K-theory. Syzygies and Homotopy Theory will be of interest to researchers and also to graduate students with a background in algebra and algebraic topology. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The growth of uro-oncology has been one of the dramatic features of the past decade in urology. Basic science research into the immunol ogy and molecular biology of cancer is beginning to impact on clinical urology and this poses a number of problems, both for practising urologists and basic scientists. If they are going to contribute to future research in this area they will have to communicate with each other: at present there is a gap which is widening at an increasingly rapid rate. One of the aims of this book is to bridge this gap by collating the views of a group of internationally distinguished scientists and clinicians in order to make this information more easily accessible. It is intended that the book will be useful to any urologist interested in recent developments in uro-oncology both at the clinical and basic science level. I believe the book has a useful function not otherwise fulfilled by present texts. The first section of the book is directed towards bladder cancer. 312 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Ever since its discovery in 1742 the carotid body has remained an organ of mystery. Originally described as a ganglion, it was subsequently regarded as a gland, chromaffin paraganglion and non-chromaffin paraganglion. In 1928 it was shown to be a chemoreceptor with close associations with the function of baroreception in the adjacent carotid sinus and perhaps within its own substance. These discoveries led physiologists to embark on a series of elegant experimental studies on a number of animal species which have, however, so far failed to identify the transducer for detection of changes in tension of arterial blood gases or the mechanism of chemor eception. Pathologists on the other hand have largely ignored the carotid body, restricting their interest to its tumour, the chemodectoma. A remarkable disparity in knowledge of the organ has resulted, with most information being available on the physiology of chemoreceptor tissue in laboratory animals. In contrast, there has been sparse interest and awareness of the pathology in man of this nodule of tissue lying in the carotid bifurcation whose functional activity is suggested by the high blood flow it receives, and its rich content of biogenic amines and a wide variety of peptides. This book is an attempt to redress this unsatisfactory situation. During the last few years our understanding of the detailed histology and ultrastructure of the human carotid body has improved. 220 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The 1992 International Yearbook of Nephrology is the 4th in a successful series of yearly books updating practising nephrologists and nephrologists-in-training on rapidly changing areas of nephrology. We were encouraged to proceed in our editorial venture by reviews of the previous issues which have appeared in various Nephrology Journals. These reviews have pointed to the successful use of the International Editorial Board, the broad range of topics of current interest which have been covered and the comprehensive and practical nature of the reviews. The principal aim of the Yearbook remains to provide reviews which are more current than those which appear in Nephrology textbooks and which can be in the hands of the readers a few months after the authors have completed the manuscripts. The appointed authors are always experts in the field, who are asked to give an objective review of the topic, up-dating the readers on the world-wide literature and providing them with a complete, accurate and up-ta-date list of important recent references. We have decided to maintain the successful format of the first three issues. Thus, the volume will continue to be divided into sections; each section will continue to have a different primary focus every year, depending upon what is of greatest interest at the time. 376 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In few areas of medicine is progress more spectacular than in the field of prenatal diagnosis. New clinical techniques such as chorion villus sampling, detailed ultrasound scanning and cordocentesis are being evaluated by obstetricians, and refinement of biochemical testing is widening the scope of maternal serum screening. In the laboratory, dramatic advances in molecular biology are occurring: families at risk of genetic disease can be investigated with gene probes, and preimplantation diagnosis of the embryo is now becom ing a reality. These technical advances have important ethical and practical implications, among which will be a further increase in public expectations of the standards required of antenatal services. Clini cians will need a high degree of skill to inform healthy women about the options for screening normal pregnancies, and to counsel high-risk women about the benefits and limitations of prenatal diagnosis. Obstetricians, scientists and health service managers will face the difficult task of deciding how prenatal diagnosis can be made available to women in a caring and cost-effective way. Recognising the rapid progress in this field, the Royal College of Obstetricians and Gynaecologists made prenatal diagnosis the subject of its 23rd Study Group. An international panel of leading researchers, whose expertise ranged from molecular biology to philosophy, was invited to participate in a three day workshop, with time for in-depth discussion as well as the presentation of papers. 384 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable.Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training. 120 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -La pathologie vasculaire a ete tres marquee par les progres biologiques de ces vingt demieres annees. Le systeme arteriel est main tenant considere comme un organe a part entiere. Modelee au cours de l'organogenese par les facteurs hemodynamiques, Ie paroi arterielle maintient une structure hautement organisee et des proprietes mecaniques qui dependent directement des conditions de pression et de debit. La monocouche endotheliale developpe 2 une surface de plusieurs centaines de m a l'interface sang-tissu; elle est a la fois un organe endocrine complexe synthetisant de nombreuses proteines qui participent a l'hemostase, une surface thromboresistante et hemocompatible, une barriere de permeabilite contr6lant les echanges sang-tissus. Les cellules musculaires lisses constituent un tissu multifonctionnel, contractile, assurant la synthese des composants structuraux responsables des proprietes mecaniques de la paroi arterielle, la transmission de la force contractile, et une etonnante activite reparatrice en reponse aux agressions. Tout ceci est soumis a un ensemble complexe de communications cellulaires qui font de l'endothelium un veritable systeme recepteur pour la paroi vasculaire. Parallelement, ou a la suite de ces progres, l'angeiologie s'est progressivement affirmee comme une specialite clinique. Debordant Ie cadre de la chirurgie vasculaire, elle integre les concepts physiopathologiques au diagnostic et au traitement des maladies arterielles. De cet effort d'integration est ne cet ouvrage, cherchant a concilier les connaissances fondamentales es plus recentes et la demarche clinique. 728 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND. 492 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although most textbooks of neurology contain a certain amount of pathological informa tion, neuropathology has often been treated in isolation. However, neuropathology has a close relationship to clinical neurology, neurosurgery and neuroradiology. Thus, advances in the rapidity and accuracy of pathological diagnosis have often led to changes in clinical management and, recently, improvements in clinical diagnosis, particularly CT scanning, have brought about a change in emphasis in the practice of neuropathology. In this textbook we have sought to present a widely based account of neuropathology in combination with information from clinical experience. We chose this approach in order to emphasize the close interrelation between clinician and pathologist. The book grew out of a course organised jointly by two neurologists and two neuropathologists from the Depart ments of Neuropathology and Neurology of The London Hospital and The University of Southampton. It is hoped that the book will be useful not only to pathologists, neurologists, neurosurgeons, and neuroradiologists, but also to general physicians. In a period of rapid advance in knowledge it is important to recognise how changes in the clinical and laboratory disciplines overlap. In order to make the most of consultations with pathologist colleagues the clinician must know what skills and techniques are available in the laboratory, and similarly, the pathologist must keep abreast of changes in clinical practice. In the past the clinician and pathologist have often been slow to appreciate advances in each other's fields. 356 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Surgeons differ in their enthusiasm for autografts, allografts and metallic implants, nevertheless, all have their place in orthopedic surgery. For some defects in the skeleton, bone grafting may be the only solution. The pros and cons of bone grafting are thoroughly discussed by eighteen distinguished authorities in this book. Their exchange of views and experiences reflects the diversity of thinking worldwide and points to exciting possibilities for future improvements. The twenty-eight chapters describe: the natural history and immunology of auto and allografting; innovative surgical techniques together with results, whether successful or not; and bone banking and its related problems, especially HIV. 248 pp. Englisch.…