Springer nature feb 1995 (14 risultati)

Buch. Condizione: Neu. Neuware - In Alcohol and Hormones, leading researchers concisely review what is known about each human hormone system and how these systems are affected by alcohol use, to a lesser extent, other drugs of abuse. The contributors show clearly just how the body is regulated and how its normal functioning can be changed by alcohol.Major topics covered range from alcohol-stress interactions and the effects of alcohol on vitamin A metabolism (fetal alcohol syndrome and neural tube development) to how alcohol blocks the release of various peptide hormones, to its effects on puberty-related events in the female. There are also articles about how alcohol affects the control of body temperature, the impact of alcohol on male sexual development during puberty, the role of TRH in alcohol use disorders, and the possibility for a neuroendocrinological component in alcoholism.Alcohol and Hormones will be of interest to biomedical and alcohol researchers, neurobiologists, endocrinologists, pharmacologists, psychiatrists, and some clinicians interested in a deeper understanding of the effects of alcohol on the body.…

Buch. Condizione: Neu. Neuware - It is recognized that formal design and verification methods are an important requirement for the attainment of high quality system designs. The field has evolved enormously during the last few years, resulting in the fact that formal design and verification methods are nowadays supported by several tools, both commercial and academic. If different tools and users are to generate and read the same language then it is necessary that the same semantics is assigned by them to all constructs and elements of the language. The current IEEE standard VHDL language reference manual (LRM) tries to define VHDL as well as possible in a descriptive way, explaining the semantics in English. But rigor and clarity are very hard to maintain in a semantics defined in this way, and that has already given rise to many misconceptions and contradictory interpretations. Formal Semantics for VHDL is the first book that puts forward a cohesive set of semantics for the VHDL language. The chapters describe several semantics each based on a different underlying formalism: two of them use Petri nets as target language, and two of them higher order logic. Two use functional concepts, and finally another uses the concept of evolving algebras. Formal Semantics for VHDL is essential reading for researchers in formal methods and can be used as a text for an advanced course on the subject.…

Buch. Condizione: Neu. Neuware - This book shows senior management how to implement TQM with clear explanations of the principles behind it. It is an indispensable guide book for senior managers in all sections of industry and commerce, at all stages of putting into practice the quality improvement process.…

Buch. Condizione: Neu. Neuware - The Office of Health and Environmental Research (OHER) has supported and continues to support development of computational approaches in biology and medicine. OHER's Radiological and Chemical Physics Program initiated development of computational approaches to determine the effects produced by radiation of different quality (such as high energy electrons, protons, helium and other heavy ions, etc. ) in a variety of materials of biological interest-such as water, polymers and DNA; these include molecular excitations and sub-excitations and the production of ionization and their spatial and temporal distribution. In the past several years, significant advances have been made in computational methods for this purpose. In particular, codes based on Monte Carlo techniques have been developed that provide a realistic description of track-structure produced by charged particles. In addition, the codes have become sufficiently sophisticated so that it is now possible to calculate the spatial and temporal distribution of energy deposition patterns in small volumes of subnanometer and nanometer dimensions. These dimensions or resolution levels are relevant for our understanding of mechanisms at the molecular level by which radiations affect biological systems. Since the Monte Carlo track structure codes for use in radiation chemistry and radiation biology are still in the developmental stage, a number of investigators have been exploring different strategies for improving these codes.…

Buch. Condizione: Neu. Neuware - EDITORS NIDI, P.O. Box 11650, 2502 AR The Hague, The Netherlands CBGS, Markiesstraat 1, 1000 Brussels, Belgium This volume is the tenth edition in the series 'Population and Family in the Low Countries'. It is published by the Netherlands Interdisciplinary Demo graphic Institute (NIDI, The Hague) together with the Flemish Population and Family Study Centre (CBGS, Brussels), with the purpose to inform an international audience on results of demographic research in Belgium and the Netherlands. The series started in 1976. From 1991 on, it is published annually. The current edition includes seven articles reflecting a selection of current research issues in the Low Countries. With permission of the Dutch and Belgian Governments the national reports submitted to the 1994 International Conference on Population and Development (Cai'ro) are also included in this volume. They provide up to date information on the official views at present of the Dutch and Belgian Government on demographic trends and population policy issues.…

Buch. Condizione: Neu. Neuware - Deryn Watson and David Tinsley The topic of the conference, integrating infonnation technology into education, is both broad and multi-facetted. In order to help focus the papers and discussion we identified 7 themes: - Current developments in society and education influencing integration; - Teachers, their roles and concerns; - Learners, their expectations of and behaviour in an integrated environment; - Developments and concerns in the curriculum; - Successes and failures in existing practice; - Organisation and management of integrated environments; - Identification of social and political influences. Each author was invited to focus on one theme, and these remained strands throughout as can be seen from the short papers and focus group reports. The first and most significant concern therefore was to be clear about our notions of integration; what do we mean and how is this relevant Our keynote paper from Cornu clearly marked out this debate by examining the notion of integration and alerting us to the fact that as long as the use of IT is still added to the curriculum, then integration has not yet begun.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Pathophysiology and Analysis.- Lipid Peroxides and Related Radicals in Clinical Medicine.- Reactive Oxygen Species in Normal Physiology, Cell Injury and Phagocytosis.- Free Radical Mechanisms for Chromosomal Instability in Bloom's Syndrome.- The Analysis of Free Radicals, Lipid Peroxides, Antioxidant Enzymes and Compounds Related to Oxidative Stress as Applied to the Clinical Chemistry Laboratory.- Organ Specific Disorders.- Free Radicals and the Pathogenesis of Neuronal Death: Cooperative Role of Excitatory Amino Acids>.- Free Radicals and Ocular Disease.- Active Oxygen Mechanisms of UV Inflammation.- Oxygen-Free Radicals at Myocardial Level: Effects of Ischaemia and Reperfusion.- Mechanisms of Atherosclerosis: Role of LDL Oxidation.- Tissue Iron Overload and Mechanisms of Iron-Catalyzed Oxidative Injury.- Free Radicals in the Pathophysiology of Pulmonary Injury and Disease.- Lipid Peroxides in Hepatic, Gastrointestinal, and Pancreatic Diseases.- Reactive Oxygen Molecules in the Kidney.- Reactive Oxygen Species (ROS) and Reproduction.- Systemic Involvement.- Autoimmune and Inflammatory Diseases.- Antioxidants and Cancer: Molecular Mechanisms.- New Directions for Free Radical Cancer Research and Medical Applications.- Shock and Multiple Organ Failure.- Role of Nutrients in the Cause and Prevention of Oxygen Radical Pathology.- Involvement of Free Radical Mechanism in the Toxic Effects of Alcohol: Implications for Fetal Alcohol Syndrome.- Therapeutic Intervention.- 21-Aminosteroids ('Lazaroids').- The Potential of Gliclazide, a Sulphonylurea to Influence the Oxidative Processes within the Pathogenesis of Diabetic Vascular Disease.- Interactions between Vitamin E, Free Radicals, and Immunity During the Aging Process.- Vitamins and Carotenoids - A Promising Approach to Reducing the Risk of Coronary Heart Disease, Cancer and Eye Diseases.- Free Radical Scavenging and Antioxidant Activity of Plant Flavonoids.- Plasma Clearance and Immunologic Properties of Long-Acting Superoxide Dismutase Prepared Using 35,000 to 120,000 Dalton Poly-Ethylene Glycol.- Clinical Trials with Dismutec(TM) (Pegorgotein; Polyethylene Glycol-Conjugated Superoxide Dismutase; PEG-SOD) in the Treatment of Severe Closed Head Injury.- Poster Presentations.- A New Method for Detecting Lipid Peroxidation by Using Dye Sensitized Chemiluminescence.- Chemiluminescence and the Challenge to Attomole Detection.- Evidence Against Malondialdehyde Bound to Cellular Consituents in Phospholipid Peroxidation.- Evaluation of In Vivo Free Radical Activity During Endotoxic Schock Using Scavengers, Electron Microscopy, Spin Traps, and Electron Paramagnetic Spectroscopy.- Involvement of Hydroxyl Radicals in Endotoxin-Evoked Shock.- The Role of Nitric Oxide in Endotoxin-Elicited Hypodynamic Circulatory Failure.- In Vivo Evaluation of the Role of Neutrophil-Derived Free Radicals in the Development of Endotoxic Shock.- Photosensitized Formation of 8-Hydroxy-2'-Deoxyguanosine by A Cationic meso-Substituted Porphyrin.- Aging Associated Declines in the Antioxidant Enzymes of Human Testis.- Lipid Peroxidation in Normal Pregnancy and Preeclampsia.- Alkylation of Purine Bases By Carbon-Centered Radicals.- Cytochrome Biochemistry in Sheep Retina Following Exposure to Oxygen.- Cytochrome Oxidase Activity in the Fetal Sheep Retina.- Age-Related Phospholipid Hydroperoxide Levels in Gerbil Brain Measured by HPLC-Chemiluminescence Assay and Their Relation to Hydroxyl Radical Stress - Clinical Implications.- Lipid Peroxidation and Diabetic Complications: Effect of Antioxidant Vitamins C and E.- Vascular Complications of Patients in Kuwait with Type 2 Diabetes Mellitus (NIDDM) and Elevated Serum Lipid Peroxides.- Vascular and Cellular Protein Changes Precede Hippocampal Pyramidal Cell Loss Following Global Ischemia in the Rat.- Dietary Antioxidants and Breast Cancer Risk: Effect Modification by Family History.- Effect of MAK-4 a.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph presents the most important results of a new branch of functional analysis: subdifferential calculus and its applications. New tools and techniques of convex and nonsmooth analysis are presented, such as Kantorovich spaces, vector duality, Boolean-valued and infinitesimal versions of nonstandard analysis, etc., covering a wide range of topics. This volume fills the gap between the theoretical core of modern functional analysis and its applicable sections, such as optimization, optimal control, mathematical programming, economics and related subjects. The material in this book will be of interest to theoretical mathematicians looking for possible new applications and applied mathematicians seeking powerful contemporary theoretical methods. 416 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Integrated Regional Modelling: Experimental and Numerical Study of High Ozone Events in the Alpine Region; J. Graf, et al. Global and Longrange Transport: A Three Dimensional Hemispheric Air Pollution Model Used for the Arctic; J. Christensen. New Developments: A Fast Lagrangian Particle Model for Use with Three-dimensional Mesoscale Models; W. Physick, P. Hurley. Accidental Release: A Mesoscale Boundary Layer Meteorological Model for Inhomogeneous Terrain; S.M. Daggupaty, et al. Model Assessment and Verification: Improving the Science of Regulatory Dispersion Models for Shortrange Applications; J.C. Weil. Video Session: Designing an Air Quality Network for Brisbane Using a Mesoscale Model; W. Physick, et al. Poster Session: Vertical Diffusion Parameter in the Atmospheric Boundary Layer; L.E. Venegas. Special Session: Athenian Photochemical Smog Intercomparison of Simulations (APSIS). Special Session: Air Pollution Transport and Diffusion over Coastal Urban Areas (Athens). 94 additional articles. Index. 724 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The first phase of transition to a market economy in Central and Eastern Europe was characterized by a sharp output decline. The fall in real GDP exceeded 20% while real industrial production decreased even by 40%. Output Decline in Eastern Europe aims at providing comprehensive, multi-factor explanations for this unique, painful experience. Various hypotheses are analyzed: credit and fiscal policies may have been too tight; the collapse of the CMEA and the USSR came as a shock; domestic producers were neither experienced, nor flexible enough to adjust the output to new patterns of demand. Output Decline in Eastern Europe contains a unique combination of authors from East and West who extensively analyze new data based on country studies. Understanding the causes of recent output decline, the subject matter of this volume may help to assess the prospects for Eastern Europe. The book is addressed to researchers and students as well as interested officials who deal with the transition of formerly centrally planned economies in Central and Eastern Europe. 402 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Decaying Two-dimensional Turbulence; W.R. Young. Experiments in 1D Turbulence; F. Daviaud. Experiments on 2D Turbulence; (Laboratory) P. Tabeling. Experiments on Spatiotemporal Chaos in Two Dimensions J.P. Gollub. Extended Self Similarity; S. Ciliberto. Hot Wire Anemometry: An Overview in Turbulence Research-Present and Future; A. Tsinober. Intermittency (Random Cascade Models, Multifractality and Large Deviations); U.Frisch. Numerical Simulations (Direct); M.E. Brachet. Numerical Simulations of Twodimensional Flows; (Turbulence and Vortices); B. Legras. Optical Turbulence; A.C. Newell, V.E. Zakharov. Phase Turbulence; H. Chaté, P. Manneville. Predictability in Turbulence; G. Paladin, et al. Probability Density Functions in 3D Turbulence; B. Castaing. Rayleigh-Bénard Turbulent Convection; A. Tilgner, et al. Scaling in Hydrodynamics; L.P. Kadanoff. Spatiotemporal Intermittency; H. Chaté, P. Manneville. Vorticity Filaments; Y. Couder, et al. 6 additional articles. Index. 164 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sir Walter Scott defined the parameters of the historical novel and illustrated his concept of the genre by writing a long series of novels dealing with medieval times, the Elizabethan Age and the 18th Century. Later novels written by his contemporaries and successors attracted smaller audiences. When Robert Louis Stevenson, in the early 1880s, enthusiastically expanded the boundaries of romantic fiction, he became a standard-bearer and an inspiration to many of his fellow-novelists: Walter Besant, Richard Doddridge Blackmore, Arthur Quiller-Couch, Arthur Conan Doyle, Stanley John Weyman, Anthony Hope, Henry Rider Haggard, and Rafael Sabatini. 189 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In an exciting and important book. The theoretical chapters are a model of elegantly styled accommodation; yet they brook no fudging of the issues, no comfortable ambiguities - Modern Fiction Studies The Transformation of the English Novel, 1890-1930: Studies in Hardy, Conrad, Joyce, Lawrence, Forster and Woolf is a provocative exploration of a crucial period in the development of the English novel, integrating critical theory, historical background and sophisticated close reading. Divided into two major sections, the first shows how historical and contextual material is essential for developing powerful readings. The second section is theoretical and speaks of the transformation in the way that we read and think about authors, readers, characters and form in the light of recent theory, offering an alternative to the deconstructive and Marxist trends in literary studies. 336 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The principal focus of this volume is to illustrate the level of accuracy currently achievable by ab initio quantum chemical calculations. While new developments in theory are discussed to some extent, the major emphasis is on a comparison of calculated properties with experiment. This focus is similar to the one taken in a book, Comparison of Ab Initio Quantum Chemistry with Experiment for Small Molecules, edited by Rodney Bartlett (Reidel, 1984). However, the phenomenal improvement in both theoretical methods and computer architecture have made it possible to obtain accurate results for rather large molecular systems. This is perhaps best illustrated in this volume by the chapter entitled `Spectroscopy of Large Organic Molecules' by Bjorn Roos and coworkers. For example, the electronic spectra of the nucleic acid base monomer structures shown on the front cover have been obtained using a fully correlated ab initio study. For researchers, teachers and students in chemistry and physics. 462 pp. Englisch.…