Springer nature okt 2001 (31 risultati)

Buch. Condizione: Neu. Neuware - 76 2. Short Oligonucleotide Mass Analysis 76 2. 1. Method Outline 76 2. 2. Design of PCR Primers and Fragments for Analysis 78 2. 3. Typical PCR Reaction Conditions 79 3. Electrospray Ionisation Mass Spectrometry 79 Formation of Ions 3. 1. 79 3. 2. Tandem Mass Spectrometry 79 3. 3. Typical ESI-MS Settings for SOMA 80 4. Purification Procedures 80 4. 1. Phenol/Chloroform Extraction and Ethanol Precipitation 80 4. 2. In-line HPLC Purification 81 5. Genotyping Using SOMA 81 5. 1. APC Genotyping in Human Subjects 81 5. 2. APC Genotyping in Min Mice 85 5. Mutation Detection Using SOMA 86 6. 1. Analysis of p53 Mutations in Liver Cancer Patients 86 6. 1. 1. p53 Mutations in Liver Tumours 87 6. 1. 2. p53 Mutations in Plasma Samples 88 7. Advantages and Disadvantages of SOMA 89 8. Future Perspectives 90 9. Acknowledgements 91 10. References 91 CHAPTER 7 WV. Bienvenut, M. Müller, PM. Palagi, E. Gasteiger, M. Heller, E. Jung, M. Giron, R. Gras, S. Gay, PA. Binz, G J. Hughes, JC. Sanchez, RD. Appel, DF. Hochstrasser Proteomics and Mass Spectrometry: Some Aspects and Recent Developments 1. Introduction to Proteomics 93 2. Protein Biochemical and Chemical Processing Followed by Mass Spectrometric Analysis 94 2. 1. 2-DE Gel Protein Separation 95 Protein Identification Using Peptide Mass Fingerprinting and Robots 96 2. 2. 2. 2. 1. MALDI-MS Analysis 98 2. 2. 2. MS/MS Analysis 102 Improvement of the Identification by Chemical Modification of Peptides 106 2. 2. 3.…

Buch. Condizione: Neu. Neuware - One morning in 1969, out of the blue, I received a letter which both distressed and astonished me. It was from a Prof. S. R. Das in Calcutta, who requested me to accept, for eventual analysis, a mountain of anthropometric data he had accumulated, as he was ill and did not expect to survive to analyse it himself. The data provided the astonishment; twenty-two anthropometric characters recorded every six months or a year, over a period of 14 years, in a mixed longitudinal study of some 560 children, aged six months to twenty years. Most were in families with siblings also in the study, and every child was measured every time by S. R. Das himself. The archive was unique, combining the personal anthropometry of R. H. Whitehouse in the Harpenden Growth Study and the family approach of the Fels Growth Study. This was a study of which neither I, nor anyone of my acquaintance, had heard. Even in India, Prof. Das' work was scarcely known. It turned out Das was a scholarly man, quiet and unassuming, absolutely committed to his Sarsuna-Barisha Growth Study,just the obverse of the professional showman. Clearly this was not a request I could refuse, although I already had in hand enough projects to occupy Siva himself.…

Buch. Condizione: Neu. Neuware - Hollywood films of the 1930s are frequently treated as if they all conformed to one cinematographic style. This book shows that this was not the case and describes the various stylistic changes in the use of the camera and lighting which took place during the decade. These changes did not, of course, occur in a vacuum and the ideological conditions in which the films were made is shown to be a crucial factor in explaining these changes. …

Buch. Condizione: Neu. Neuware - Sizes of electronic and photonic devices are decreasing drastically in order to increase the degree of integration for large-capacity and ultrahigh speed signal transmission and information processing. This miniaturization must be rapidly progressed from now onward. For this progress, the sizes of materials for composing these devices will be also decreased to several nanometers. If such a nanometer-sized material is combined with the photons and/or some other fields, it can exhibit specific characters, which are considerably different from those ofbulky macroscopic systems. This combined system has been called as a mesoscopic system. The first purpose of this book is to study the physics of the mesoscopic system. For this study, it is essential to diagnose the characteristics of miniaturized devices and materials with the spatial resolution as high as several nanometers or even higher. Therefore, novel methods, e.g., scanning probe microscopy, should be developed for such the high-resolution diagnostics. The second purpose of this book is to explore the possibility of developing new methods for these diagnostics by utilizing local interaction between materials and electron, photon, atomic force, and so on. Conformation and structure of the materials of the mesoscopic system can be modified by enhancing the local interaction between the materials and electromagnetic field. This modification can suggest the possibility of novel nano-fabrication methods. The third purpose of this book is to explore the methods for such nano-fabrication. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Why has Russian democracy apparently survived and even strengthened under a presidential system, when so many other presidential regimes have decayed into authoritarian rule And what are the origins of presidential power in modern Russia Thomas M. Nichols argues that the answer lies in the relationship between political institutions and trust: where society, and consequently politics, is fractious and divided, structural safeguards inherent in presidentialism actually serve to strengthen democratic behavior. The Russian presidency is not the cause of social turmoil in Russia, but rather a successful response to it. This book's emphasis on the social origins of Russian politics explains not only the unexpected survival of Russian democracy, but encourages a reconsideration of the relationship between institutions, social conditions, and democracy. 235 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As the end of the century draws closer, one of the most pressing challenges facing educators in the United States is the specter of an 'ethnic and cultural war' - a code phrase that engenders our society's licentiousness toward racism. In Dancing With Bigotry, Macedo and Bartolomé use examples from the mass media, popular culture, and politics to illustrate the larger situations facing educators and how this type of argument is both ignored in much of the academic research and rhetoric. They also examine why it is essential to take on the sources of 'mass public education.' Academia needs to understand that the popular press and mass media educate more people about issues regarding ethnicity and race than all other sources of education available to U.S. citizens. By shunning the mass media, educators are missing the obvious - more public education is done by the media than by teachers, professors, or anyone else. Dancing with Bigotry sheds light on the ideological mechanisms that shape and maintain the racist social order, while moving the discussion beyond the reductionist binarism of White versus Black racism. Discussing social complexities, including ethnic cleansing, culture wars, hegemony, human sufferings, and intensified xenophobia, Macedo and Bartolomé explain why it is essential that we gain a nuanced understanding of how ideology underlies all social, cultural, and political discourse and actions. This book shows that it is imperative that we appreciate what it means to educate for critical citizenry in the ever-increasing multiracial and multicultural world of the twentieth century. 175 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dialogue on the conflict between religious fundamentalism and women's rights is often stymied by an 'all or nothing' approach: fundamentalists claim of absolute religious freedom, while some feminists dismiss religion entirely as being so imbued with patriarchy as to be eternally opposed to women's rights. This ignores, though, the experiences of religious women who suffer under fundamentalism and fight to resist it, perceiving themselves to be at once religious and feminist. In Religious Fundamentalisms and the Human Rights of Women , Howland provides a forum for these different scholars, both religious and nonreligious, to meet and seek common ground in their fight against fundamentalism. Through an examination of international human rights, national law, grass roots activism, and theology, this volume explores the acute problems that contemporary fundamentalist movements pose for women's equality and liberty rights. 326 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides practical advice from the Chief Executive of one of the biggest PR firms in the world on how to manage your personal PR. Explaining how to develop your career, promote your business or carry out campaigns for change he focuses upon reputation as the key to world class individuals, companies and great brands. Including many compelling examples and cases the book includes a toolkit and practical plans for doing this for yourself. 192 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leadership is currently one of the most hotly discussed topics in business. This is the first book to not only identify the characteristics of successful leadership but to show how these qualities can be developed. The Reflecting Glass surveys the field of executive coaching, including its origins, the theoretical framework underpinning it, the forms it can take and the value it adds. Based on the experience of two leading practitioners and with contributions from other key players it provides a detailed methodology for working one-to-one with people at the top of organisations in order to help them become fully effective. Executive coaching has experienced exponential growth over the last five years but as yet there has been little critical appraisal of the activity. This book provides that critique. By describing and benchmarking good practice, The Reflecting Glass will be a valuable tool for those in leadership positions considering executive coaching for themselves, as well as the HR professional. 209 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Bible serves Wordsworth as a basis for his poetry and poetics, providing language, images, figures, and importantly, a paradigm of poetic genres. Working from three interrelated critical approaches - intertextuality, poetics, and metaphysics - Westbrook first analyzes Wordsworth's theory and practice as these reflect the New Testament doctrine of the Incarnation. Subsequent chapters consider Wordsworth's adaptation of biblical narrative forms - etymological tales, parables, and mystical allegories. Closing chapters examine some extraordinary linguistic innovations in Wordsworth's revisions of biblical apocalypse, techniques that permit the poet to express the ineffable and to reveal nothing. 244 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Imagining Columbus is Stavans's contribution to the literature on Columbus. 'My purpose,' says Stavans, 'is to revisit, to investigate, to play with the asymmetrical geometries of the admiral's literary adventures in the human imagination.' Arguing that writers have portrayed Columbus in three ways-as prophet or messiah, as ambitious gold-seeker, and as a conventional, rather unremarkable man-Stavans examines numerous poems, novels, short stories, dramas, and other works on Columbus in this provocative book. In Part 1, 'Mapmaking,' Stavans explores the two opposing views of the celebration of the quincentennial, and discusses the most notable biographies of Columbus, including those by Washington Irving and Samuel Eliot Morison. In Part 2, 'Lives of a Literary Character,' Stavans takes up the geographic and historical development of Columbus as a narrative figure in literature, and devotes a chapter to each of the three literary views of the admiral. Stavans includes portrayals of other writers' views on Columbus like Walt Whitman, Alejo Carpentier, James Fenimore Cooper, Friedrich Nietzsche, Nikos Kazantzakis, Rubén Darío, Michael Dorris, Louise Erdrich, among others. 169 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -UNICEF, the UN Children's Fund, is renowned for its efficiency in both rich and poor countries. Created as a humanitarian agency, it is now one of the international development institutions concerned with children and mothers. The book relates the creation of UNICEF, the evolution of its programmes, its structure and finances, its work in health, nutrition, education and sanitation and in emergencies. The 1989 Convention on the Rights of the Child now serves as a framework for all UNICEF programmes and a basis for its advocacy. Current challenges include UNICEF's nature and identity, its relationship with other international organizations, reduced funding and its need to refocus some of its programmes. 225 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is designed to help the reader better understand the conduct of war by focusing on the 'how' not the 'why' of warfare. It examines a number of crucial dimensions of contemporary armed conflict such as: the strategies, operations, tactics, doctrines and weapons of conventional and low-intensity war; military geography; the cultural underpinnings of strategies and tactics; arms resupply, security assistance, and foreign intervention. 413 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Eero Palmujoki examines the regionalist debate in Southeast Asia from the end of the Cold War up to the beginning of the new millennium. He focuses on the organization of the ASEAN (Association of Southeast Asian Nations) and covers the political, economic and security issues characterizing its development. The book compares the theoretical debate with political developments in the region, from the beginning of the post-Cold War period with its rapid economic growth through the Asian economic crisis of 1997 and the resulting restructuring of Southeast-Asian regional systems. 226 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -An inspiring collection that uses case studies and theoretical reflection to contextualise the linkages between collective action theories, social movement practices and the phenomenon of globalisation. All of the perspectives presented will force a rethink of the exact meaning of globalisation and the way in which such insights can be used to advance understanding of basic transformations occurring in the diverse world of the twenty-first century. 258 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Despite the regional currency crisis of 1997-1998, Asia-Pacific economies continue to be among the most attractive markets in the world. Although Japanese and American firms have invested heavily in the past decades, European firms are poised to take advantage of the post-Asian recovery, phenomenal Chinese growth rates, and deepening economic liberalization. This volume focuses on understanding the market and nonmarket strategies employed by European firms to boost their share of the Asian market and to rally European governments and the European Union in support of their initiatives. In addition to a novel theoretical framework to analyze strategy, three chapters focus on investment trends in Asia, lobbying in Asia and the EU, the book includes original case studies of the air transport, automobile, software, and finance sectors. 290 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The involvement of non-state actors in world politics can hardly be characterised as novel, but intensifying economic and social exchange and the emergence of new modes of international governance have given them much greater visibility and, many would argue, a more central role. Non-state Actors in World Politics offers analyses of a diverse range of economic, social, legal (and illegal), old and new actors, such as the Catholic Church, trade unions, diasporas, religious movements, transnational corporations and organised crime. 294 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many of the deep-rooted human conflicts that seize our attention today are not ready for formal mediation and negotiation. People do not negotiate about identity, fear, historic grievance, and injustice. Sustained dialogue provides a space where citizens outside government can change their conflictual relationships. Governments can negotiate binding agreements and enforce and implement them, but only citizens can change human relationships. Governments have long had their tools of diplomacy - mediation, negotiation, force, and allocation of resources. Harold H. Saunders' A Public Peace Process provides citizens outside government with their own instrument for transforming conflict. Saunders outlines a systematic approach for citizens to use in reducing racial, ethnic, and other deep-rooted tensions in their countries, communities, and organizations. 328 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Same-Sex Love in India presents a stunning array of writings on same-sex love from over 2000 years of Indian literature. Translated from more than a dozen languages and drawn from Hindu, Buddhist, Muslim, and modern fictional traditions, these writings testify to the presence of same-sex love in various forms since ancient times, without overt persecution. This collection defies both stereotypes of Indian culture and Foucault's definition of homosexuality as a nineteenth-century invention, uncovering instead complex discourses of Indian homosexuality, rich metaphorical traditions to represent it, and the use of names and terms as early as medieval times to distinguish same-sex from cross-sex love. An eminent group of scholars have translated these writings for the first time or have re-translated well-known texts to correctly make evident previously underplayed homoerotic content. Selections range from religious books, legal and erotic treatises, story cycles, medieval histories and biographies, modern novels, short stories, letters, memoirs, plays and poems. From the Rigveda to Vikram Seth, this anthology will become a staple in courses on gender and queer studies, Asian studies, and world literature. 370 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our poorest urban neighbourhoods experience economic and social difficulties that uniquely affect the lives of those who live there. This volume examines the policies and initiatives now underway on both sides of the Atlantic to revitalize those areas. With contributors from the US, France and the UK the volume explains the nature of specific community building programmes and explores critical issues such as the role of partnerships and the importance of race and gender in urban regeneration. 234 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Operational risk is one of the oldest risks in the banking sector, and yet regulatory bodies including the Basle Committee are still working on a regulatory framework. Damage control measures introduced by banks have often proved ineffective. The successful management of operational risk requires preventative action and will be a significant competitive advantage for banks in the future. This book is a practical guide to achieving control of operational risk. Using qualitative analysis, the author suggests risk identification procedures and provides tools for the analysis, quantification and management of risk. He goes on to discuss future developments in both the regulatory and insurance sectors, including the most recent Basle Committee proposals. 156 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Globalization means that today, more than ever before, growth in developing countries and the reduction of poverty depend on world trade and a well functioning trading system. This volume reviews developing countries trade policies and institutions, and the challenges they face in the World Trade Organization - where the rules that govern the international trading system are set. 278 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On the eve of the Pacific war (1941-45), there were 198,000 Japanese in Brazil, the largest expatriate body outside East Asia. Yet the origins of this community have been obscured. The English-language library is threadbare while Japanese scholars routinely insist that life outside of Japan was filled with shock and hardship so that, as one historian asserted, 'their bodies were in Brazil but their minds were always in Japan'. This study redraws the world of the overseas Japanese. Using the Japanese-language press of Brazil, it explains the development of a community with its own, often aggressively independent or ironic views of identity, institutions, education, leisure, and on Japan itself. Emphasising the success of Japanese migrants and the openness of Brazilian society, it challenges the perceived wisdom that contact between Japanese and other peoples was always marked by hostility and racism. 209 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The United Nations and Human Security highlights and analyzes the changing peace and security challenges faced by the United Nations in an evolving international environment that is no longer solely characterized by states and inter-state security. The authors, who comprise both scholars and UN practitioners, cover a wide range of pressing current issues - including refugees, international tribunals, the promotion of democracy, ethics, regional organizations, humanitarian intervention, conflict prevention and peacekeeping - that form a cutting-edge and controversial security agenda. 231 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Ivan IV, the sixteenth-century Russian tsar notorious for his reign of terror, became an unlikely national hero in the Soviet Union during the 1940s. This book traces the development of Ivan's positive image, placing it in the context of Stalin's campaign for patriotism. In addition to historians' images of Ivan, the author examines literary and artistic representations, including Sergei Eisenstein's famous film, banned for its depiction of the tsar which was interpreted as an allegorical criticism of Stalin. 255 pp. Englisch. …

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -David Martin Jones examines how China has been portrayed in European and subsequently North American social and political thought and what, if anything, this depiction tells us about the character of this thought. Such a question immediately evokes the spectre of orientalism and subsequent chapters explore whether the identification of an orientalist project invalidates the knowledge claims of European and North American social and political thought as it evolved from the eighteenth to the twentieth century. 238 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The twentieth century posed great challenges for British foreign policymakers. How effectively did they cope with decline and change Were they as pragmatic as they claimed Are there identifiable patterns of success and failure These are the questions Peter Mangold answers in the first thematic account of British foreign policy between 1900 and 2000. Issues covered include Imperial overstretch, the reluctance to engage politically or militarily with Europe, alliance management, force, loss of Great Power status, Britain's impact on the international system and future prospect. 243 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mohamad Tavakoli-Targhi offers a corrective to recent works on Orientalism that focus solely on European scholarly productions without exploring the significance of native scholars and vernacular scholarship to the making of Oriental studies. He brings to light a wealth of eighteenth- and nineteenth-century Indo-Persian texts, made 'homeless' by subsequent nationalist histories and shows how they relate to Indo-Iranian modernity. In doing so, he argues for a radical rewriting of Iranian history with profound implications for Islamic debates on gender. 216 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This highly accessible, lively and informative study gives a clear and comprehensive overview of recent trends in American crime fiction. Building on a discussion of the immediate predecessors, Bertens and D'haen focus on the work of popular and award-winning authors of the last fifteen years. Particular attention is given to writers who have reworked established conventions and explored new directions, especially women and those from ethnic minorities. 233 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers the rare opportunity to assess, within a single volume, the leading schools of thought in contemporary philosophy of religion. Their exponents seek to meet objections made to their point of view and to relate it to the other schools represented. Further discussions between adherents of the different schools make it an ideal text for assessing the deep proximities and divisions which characterize contemporary philosophy of religion. The schools of thought represented are: Philosophical Theism, Reformed Epistemology, Wittgensteinianism, Postmodernism, Critical Theory and Process Thought. 308 pp. Englisch.…