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Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0306463377ISBN 13: 9780306463372
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a thoroughgoing revision of the first edition of this classic text and reference, published by Plenum in 1992. The authors convey the general principles that underlie this applied subdiscipline and demonstrate how the merging of demography and health care impacts on the planning processes of a range of health care organizations. 384 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792365992ISBN 13: 9780792365990
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A trustworthy record is one that is both an accurate statement of facts and a genuine manifestation of those facts. Record trustworthiness thus has two qualitative dimensions: reliability and authenticity. Reliability means that the record is capable of standing for the facts to which it attests, while authenticity means that the record is what it claims to be. This study explores the evolution of the principles and methods for determining record trustworthiness from antiquity to the digital age, and from the perspectives of law and history. It also examines recent efforts undertaken by researchers in the field of archival science to develop methods for ensuring the trustworthiness of records created and maintained in electronic systems. Audience: The target audience for this study is legal scholars working in the field of evidence law, historians working in the field of historical methodology, and recordkeeping professionals (records managers, information technology specialists, archivists) working on the design and implementation of contemporary organizational recordkeeping systems. 184 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366425ISBN 13: 9780792366423
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I want to thank R. L. Fosdick, M. E. Gurtin and W. O. Williams for their detailed criticism of the manuscript. I also thank F. Davi, M. Lembo, P. Nardinocchi and M. Vianello for valuable remarks prompted by their reading of one or another of the many previous drafts, from 1988 to date. Since it has taken me so long to bring this writing to its present form, many other colleagues and students have episodically offered useful comments and caught mistakes: a list would risk to be incomplete, but I am heartily grateful to them all. Finally, I thank V. Nicotra for skillfully transforming my hand sketches into book-quality figures. P. PODIO-GUIDUGLI Roma, April 2000 Journal of Elasticity 58: 1-104,2000. 1 P. Podio-Guidugli, A Primer in Elasticity. 2000 Kluwer Academic Publishers. CHAPTER I Strain 1. Deformation. Displacement Let 8 be a 3-dimensional Euclidean space, and let V be the vector space associated with 8. We distinguish a point p E 8 both from its position vector p(p):= (p-o) E V with respect to a chosen origin 0 E 8 and from any triplet (~1, ~2, ~3) E R3 of coordinates that we may use to label p. Moreover, we endow V with the usual inner product structure, and orient it in one of the two possible manners. It then makes sense to consider the inner product a . 124 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366301ISBN 13: 9780792366300
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the most important issues in the construction of future magnetic confinement fusion machines is that of the materials of which they are constructed, and one of the key points of proper material choice is the recycle of hydrogen isotopes with materials at the plasma face. Tritium machines demand high safety and economy, which in turn requires the lowest possible T inventory and smallest possible permeation through the plasma facing materials. The recycle behaviour of the in-vessel components must also be known if the plasma reaction is to predictable and controllable, and finally, the fuel cycle and plasma operating regimes may be actively controlled by special materials and methods. The book discusses both laboratory experiments exploring the basic properties of non-equilibrium hydrogen-solid systems (diffusion, absorption, boundary processes) and experimental results obtained from existing fusion machines under conditions simulating future situations to some extent. Contributions are from experts in the fields of nuclear fusion, materials science, surface science, vacuum science and technology, and solid state physics. 376 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792365186ISBN 13: 9780792365181
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Modern approaches to microbial classification and identification, particularly those based on nucleic acid analysis, have raised the awareness and interest of microbiologists in systematics during the past decade. The extended scope of the subject has revolutionized microbial ecology with the demonstration of uncultivable microorganisms as a major component of the biosphere and evolution, with the ribosomal RNA phylogenetic tree as the basis of current classifications. However, advances in microbial systematics have also had enormous impact on other, diverse aspects of microbiology such as animal pathogenicity, plant-microbe interactions and relationships with food. In this book, we survey and discuss in depth the contribution of modern taxonomic approaches to our understanding of the microbiology of these various systems. The book does not concentrate on methods - these have been well reported elsewhere - instead it provides a unique insight into the application and value of modern systematics in diverse branches of microbiology. It will be of value to microbiologists at both research and technical levels who need to appreciate the range of organisms with which they work and the diversity within them. It will also be of value to teachers and students of microbiology courses who want to understand how systematics can enhance microbiology beyond the routine of classification, nomenclature, and identification. 496 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792367723ISBN 13: 9780792367727
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Models and modelling play a central role in the nature of science, in its conduct, in the accreditation and dissemination of its outcomes, as well as forming a bridge to technology. They therefore have an important place in both the formal and informal science education provision made for people of all ages. This book is a product of five years collaborative work by eighteen researchers from four countries. It addresses four key issues: the roles of models in science and their implications for science education; the place of models in curricula for major science subjects; the ways that models can be presented to, are learned about, and can be produced by, individuals; the implications of all these for research and for science teacher education. The work draws on insights from the history and philosophy of science, cognitive psychology, sociology, linguistics, and classroom research, to establish what may be done and what is done. The book will be of interest to researchers in science education and to those taking courses of advanced study throughout the world. 404 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366328ISBN 13: 9780792366324
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers an original and distinct analysis of NATO's post-Cold War evolution. Unlike so much of the available literature, it is not focused on what in the author's opinion NATO should be doing now that the Cold War is over. Rather, the author offers a comprehensive analysis and overview of the extent to which NATO can undertake new roles, tasks and missions in light of the extent to which it has retained significance and vitality as an international institution. The book's originality also lies in the way in which the author discusses NATO's adaptation within a framework provided by international relations theory, and in particular concepts which stress the role and importance of transnational political processes and international regimes. So far these have been little used in the analysis of military security relations and institutions. The book will be of interest to those researching and teaching international relations, European politics and security studies, as well as all those seeking a better understanding of the post-Cold War survival and development of a key international security institution. 196 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366352ISBN 13: 9780792366355
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -he present book and its companion volume The Tensed Theory of Time: a T Critical Examination are an attempt to adjudicate what one recent discussant has called 'the most fundamental question in the philosophy of time,' namely, 'whether a static or a dynamic conception ofthe world is correct. '] I had originally intended to treat this question in the space of a single volume; but the study swelled into two. I found that an adequate appraisal of these two competing theories of time requires a wide-ranging discussion of issues in metaphysics, philosophy of language, phenomenology, philosophy of science, philosophy of space and time, and even philosophy of religion, and that this simply could not be done in one volume. If these volumes succeed in making a contribution to the debate, it will be precisely because of the synoptic nature of the discussion therein. Too often the question of the nature of time has been prematurely answered by some philosopher or physicist simply because he is largely ignorant of relevant discussions outside his chosen field of expertise. In these two complementary but independent volumes I have attempted to appraise what I take to be the most important arguments drawn from a variety of fields for and against each theory of time. 276 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792367235ISBN 13: 9780792367239
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -ANTONIS BOTINIS 1. 1 Background This introduction provides essential information about the structure and the objects of study of this volume. Following the introduction, fourteen papers which represent current research on intonation are organised into five thematic sections: (I) Overview of Intonation, (II) Prominence and Focus, (III) Boundaries and Discourse, (IV) Intonation Modelling, and (V) Intonation Technology. Within the sections the papers are arranged thematically, although several papers which deal with various aspects of intonation and prosody are basically intersectional. As the title indicates, 'Intonation: Analysis, Modelling and Technology' is a contribution to the study of prosody, with major emphasis on intonation. Intonation and tonal themes are thus the central object of the volume, although temporal and dynamic aspects are also taken into consideration by a good number of papers. Although tonal and prosodic distinctions have been dealt with throughout man's literate history with reference to the study of language, for example by classical philosophers such as Plato and Aristotle, it is in recent decades that we have witnessed the most fertile growth in intonation studies, as with experimental phonetics and speech technology in general. As Rossi (this volume) points out, intonation research really began to blossom in the sixties with a multi fold increase in prosodic studies, reflected in contributions to the International Congress of Phonetic Sciences (ICPhS), and in the international literature. 412 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792367138ISBN 13: 9780792367130
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -John Maynard Keynes wrote to his grandchildren more than fifty years ago about their economic possibilities, and thus about our own: 'I see us free, there fore, to return to some of the most sure and certain principles of religion and traditional virtue - that avarice is a vice, that the exaction of usury is a misde meanour. . . . We shall once more value ends above means and prefer the good to the useful' ('Economic Possibilities for Our Grandchildren,' pp. 371-72). In the year 1930 Keynes regarded these prospects as realizable only after a time span ofone hundred years, ofwhich we have now achieved more than half. The pres ent book does not share Keynes's view that the possibility of an integration of ethics and economics is dependent exclusively on the state of economic devel opment, though this integration is certainly made easier by an advantageous total economic situation. The conditions of an economy that is becoming post of ethics, cultural industrial and post-modern are favorable for the unification theory, and economics. Economic development makes a new establishment of economic ethics and a theory ofethical economy necessary. Herdecke and Hanover, October 1987 P. K. TABLE OF CONTENTS Foreword v Introduction . 0. 1. Ethical Economy and Political Economy . . 0. 1. 1. Ethical Economy as Theory ofthe Ethical Presuppositions of the Economy and Economic Ethics 3 0. 1. 2. 300 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792364090ISBN 13: 9780792364092
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Predicates and their Subjects is an in-depth study of the syntax-semantics interface focusing on the structure of the subject-predicate relation. Starting from where the author's 1983 dissertation left off, the book argues that there is syntactic constraint that clauses (small and tensed) are constructed out of a one-place unsaturated expression, the predicate, which must be applied to a syntactic argument, its subject. The author shows that this predication relation cannot be reduced to a thematic relation or a projection of argument structure, but must be a purely syntactic constraint. Chapters in the book show how the syntactic predication relation is semantically interpreted, and how the predication relation explains constraints on DP-raising and on the distribution of pleonastics in English. The second half of the book extends the theory of predication to cover copular constructions; it includes an account of the structure of small clauses in Hebrew, of the use of `be' in predicative and identity sentences in English, and concludes with a study of the meaning of the verb `be'. 372 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792363604ISBN 13: 9780792363606
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants. 300 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366387ISBN 13: 9780792366386
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our views and understanding of variations in climate, geomorphological processes and the interrelationships that exist between climatic changes and land surface changes, both now and in the past, have developed greatly over the last decade. This book aims to encapsulate some of these recent advances and focuses on the integration of research that has been conducted by geomorphologists and climatologists on linking climate and land surface changes. This book is divided into two main parts: Section A incorporates research that has concentrated on short-term variations in climate, whilst Section B looks at some of the work on long-term climate variability. The volume concludes with a summary chapter that brings together the various ideas that have been presented in this work and other recent research in this general field. This text will be of interest to upper level students of geomorphology, Quaternary studies, climatology, earth sciences, and environmental studies. It will also be of use to researchers in these fields. 284 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792364449ISBN 13: 9780792364443
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent years have brought an upsurge of interest in the study of arbuscular mycorrhizal (AM) fungi, partly due to the realization that the effective utilization of these symbiotic soil fungi is likely to be essential in sustainable agriculture. Impressive progress has been made during the last decade in the study of this symbiosis largely as a result of increasing exploitation of molecular tools. Although early emphasis was placed on the use of molecular tools to study physiological processes triggered by the symbiosis, such as expression of symbiosis-specific polypeptides and modulation of host defences, other applications await. It was obvious to us that gathering leaders in the field to summarize these topics and point out research needs was necessary if we were to understand the physiology and function of AM fungi at a molecular level. In addition, we have taken the opportunity to present these reviews in a logical sequence of topics ranging from the initiation of the life cycle of the fungus to its functions in plant growth and in the below ground ecosystem. It was a challenge to limit this flood of information to the confines of one text. This is a very exciting time for mycorrhiza biologists and it is our hope that some of this excitement is conveyed to our readers. 382 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0412842807ISBN 13: 9780412842801
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As well as examining successful biological control programmes this book analyses why the majority of attempts fail. Off-target and other negative effects of biological control are also dealt with. Chapters contributed by leading international researchers and practitioners in all areas of biological control afford the book a breadth of coverage and depth of analysis not possible with a single author volume. Combined with the use of other experts to review chapters and editorial oversight to ensure thematic integrity of the volume, this book provides the most authoritative analysis of biological control published. Key aspects addressed include how success may be measured, how successful biological control has been to date and how may it be made more successful in the future. With extensive use of contemporary examples, photographs, figures and tables this book will be invaluable to advanced undergraduate and postgraduate students as well as being a `must' for all involved in making biological control successful. 444 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366719ISBN 13: 9780792366713
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research and publications in the field of Astronomy have undergone dramatic changes in the last half-century. While activities just slowed down during World War II in the US and in Latin America, they were very strongly affected by the difficult conditions prevailing among the European belligerent nations. Half a century ago, re search activities were mostly confined to observatories (linked or not to universities) and usually separated from the teaching of physical sciences. Hence, directors of observatories played an important role in the choice of the research fields, and 'schools' of research appeared at various places, de veloping specific instrumentation, reduction techniques and mathematical methods to achieve their scientific goals. Reorganising the research activities after the war was no minor under taking, specially because communications were interrupted for over five years and isolated continental Europe from overseas activities. Scarcity of observing instruments (some of them being requisitioned by occupy ing armies) , enormous gaps in the available litterature led to local research activities, conducted independently of similar efforts undertaken elsewhere. 236 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366484ISBN 13: 9780792366485
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The earliest experimental data on an oxygen-free glass have been published by Schulz-Sellack in 1870 [1]. Later on, in 1902, Wood [2], as well as Meier in 1910 [3], carried out the first researches on the optical properties of vitreous selenium. The interest in the glasses that exhibit transparency in the infrared region of the optical spectrum rose at the beginning of the twentieth century. Firstly were investigated the heavy metal oxides and the transparency limit was extended from (the case of the classical oxide glasses) up to wavelength. In order to extend this limit above the scientists tried the chemical compositions based on the elements of the sixth group of the Periodic Table, the chalcogens: sulphur, selenium and tellurium. The systematic research in the field of glasses based on chalcogens, called chalcogenide glasses, started at the middle of our century. In 1950 Frerichs [4] investigated the glass and published the paper: 'New optical glasses transparent in infrared up to 12 . Several years later he started the study of the selenium glass and prepared several binary glasses with sulphur [5]. Glaze and co-workers [6] developed in 1957 the first method for the preparation of the glass at the industrial scale, while Winter-Klein [7] published reports on numerous chalcogenides prepared in the vitreous state. 392 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792367286ISBN 13: 9780792367284
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the last decade, the role of computational simulations in all aspects of aerospace design has steadily increased. However, despite the many advances, the time required for computations is far too long. This book examines new ideas and methodologies that may, in the next twenty years, revolutionize scientific computing. The book specifically looks at trends in algorithm research, human computer interface, network-based computing, surface modeling and grid generation and computer hardware and architecture. The book provides a good overview of the current state-of-the-art and provides guidelines for future research directions. The book is intended for computational scientists active in the field and program managers making strategic research decisions. 308 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792364716ISBN 13: 9780792364719
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -D. Hilbert, in his famous program, formulated many open mathematical problems which were stimulating for the development of mathematics and a fruitful source of very deep and fundamental ideas. During the whole 20th century, mathematicians and specialists in other fields have been solving problems which can be traced back to Hilbert's program, and today there are many basic results stimulated by this program. It is sure that even at the beginning of the third millennium, mathematicians will still have much to do. One of his most interesting ideas, lying between mathematics and physics, is his sixth problem: To find a few physical axioms which, similar to the axioms of geometry, can describe a theory for a class of physical events that is as large as possible. We try to present some ideas inspired by Hilbert's sixth problem and give some partial results which may contribute to its solution. In the Thirties the situation in both physics and mathematics was very interesting. A.N. Kolmogorov published his fundamental work Grundbegriffe der Wahrschein lichkeitsrechnung in which he, for the first time, axiomatized modern probability theory. From the mathematical point of view, in Kolmogorov's model, the set L of ex perimentally verifiable events forms a Boolean a-algebra and, by the Loomis-Sikorski theorem, roughly speaking can be represented by a a-algebra S of subsets of some non-void set n. 564 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792365941ISBN 13: 9780792365945
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We are facing global issues concerning environmental pollution and shortages of food, feed, phytomass (plant biomass) and natural resources, which will become more serious in the forthcoming decades. To solve these issues, immeasurable numbers of various plants and huge amounts of phytomass are required every year for food, feed and for the improvement of amenities, the environment and our quality of life. Increased phytomass is also required as alternative raw material for producing bio-energy, biodegradable plastics and many other plant-originated industrial products. Only by using phytomass as a reproducible energy source and raw material, instead of fossil fuels and atomic power, we can save natural resources and minimize environmental pollution. To increase phytomass globally, we need billions of quality transplants (small plants) to be grown yearly, in the field or in the greenhouse, under various environmental conditions. However, these high quality transplants can be produced only under carefully controlled, rather than variable environment al conditions. Recent research has shown that the closed transplant production system requires considerably small amounts of electricity, water, fertilizer, CO) and pesticide to produce value-added transplants as scheduled with minimum release of environmental pollutants and minimum loss of transplants. The closed or closed-type transplant production system is defined as a transplant production system covered with opaque walls with minimized or controlled ventilation rates, using artificial lighting. With this system, photoperiod, light intensity and quality, air temperature, humidity, CO) concentration and air current speed can be controlled as desired. 304 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 079236693XISBN 13: 9780792366935
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the last years, it was observed an increasing interest of computer scientists in the structure of biological molecules and the way how they can be manipulated in vitro in order to define theoretical models of computation based on genetic engineering tools. Along the same lines, a parallel interest is growing regarding the process of evolution of living organisms. Much of the current data for genomes are expressed in the form of maps which are now becoming available and permit the study of the evolution of organisms at the scale of genome for the first time. On the other hand, there is an active trend nowadays throughout the field of computational biology toward abstracted, hierarchical views of biological sequences, which is very much in the spirit of computational linguistics. In the last decades, results and methods in the field of formal language theory that might be applied to the description of biological sequences were pointed out. 468 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366336ISBN 13: 9780792366331
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the next couple of years the human genome will be fully sequenced. This will provide us with the sequence and overall function of all human genes as well as the complete genome for many micro-organisms. Subsequently it is hoped, by means of powerful bioinformatic tools, to determine the gene variants that contribute to various multifactorial diseases and genes that exist in certain infectious agents but not humans. As a consequence, this will allow us to define the most appropriate levels for drug intervention. It can be expected that the number of potential drug targets will increase, possibly by a factor of 10 or more. Nevertheless, sequencing the human genome or, for that matter, the genome of other species will only be the starting point for the understanding of their biological function. Structural genomics is a likely follow-up, combined with new techniques to validate the therapeutic relevance of such newly discovered targets. Accordingly, it can be expected that in the near future we will witness a substantial increase in novel putative targets for drugs. To address these new targets effectively, we require new approaches and innovative tools. At present, two alternative, yet complementary, techniques are employed: experimental high-throughput screening (HTS) of large compound libraries, increasingly provided by combinatorial chemistry, and computational methods for virtual screening and de novo design. As kind of status report on the maturity of virtual screening as a technique in drug design, the first workshop on new approaches in drug design and discovery was held in March 1999, at Schloß Rauischholzhausen, near Marburg in Germany. More than 80 scientists gathered and discussed their experience with the different techniques. The speakers were invited to summarize their contributions together with their impressions on the present applicability of their approach. Several of the speakers followed this request which is summarized in this publication. 312 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 079236533XISBN 13: 9780792365334
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Before Machiavelli, political freedom was approached as a problem of the best distribution of the functions of ruler and ruled. Machiavelli changed the terms of freedom, requiring that its discourse address the demand for no-rule or non-domination. Political freedom would then develop only through a strategy of antagonism to every form of legitimate domination. This leads to the emergence of modern political life: any institution that wishes to rule legitimately must simultaneously be inscribed with its immanent critique and imminent subversion. For Machiavelli, the possibility of instituting the political form is conditioned by the possibility of changing it in an event of political revolution. This book shows Machiavelli as a philosopher of the modern condition. For him, politics exists in the absence of those absolute moral standards that are called upon to legitimate the domination of man over man. If this understanding lies open to relativism and historicism, it does so in order to render effective the project of reinventing the sense of human freedom. Machiavelli's legacy to modernity is the recognition of an irreconcilable tension between the demands of freedom and the imperatives of morality. 372 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366050ISBN 13: 9780792366058
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -ANTONIS BOTINIS 1. 1 Background This introduction provides essential information about the structure and the objects of study of this volume. Following the introduction, fourteen papers which represent current research on intonation are organised into five thematic sections: (I) Overview of Intonation, (II) Prominence and Focus, (III) Boundaries and Discourse, (IV) Intonation Modelling, and (V) Intonation Technology. Within the sections the papers are arranged thematically, although several papers which deal with various aspects of intonation and prosody are basically intersectional. As the title indicates, 'Intonation: Analysis, Modelling and Technology' is a contribution to the study of prosody, with major emphasis on intonation. Intonation and tonal themes are thus the central object of the volume, although temporal and dynamic aspects are also taken into consideration by a good number of papers. Although tonal and prosodic distinctions have been dealt with throughout man's literate history with reference to the study of language, for example by classical philosophers such as Plato and Aristotle, it is in recent decades that we have witnessed the most fertile growth in intonation studies, as with experimental phonetics and speech technology in general. As Rossi (this volume) points out, intonation research really began to blossom in the sixties with a multi fold increase in prosodic studies, reflected in contributions to the International Congress of Phonetic Sciences (ICPhS), and in the international literature. 412 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366522ISBN 13: 9780792366522
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Models and modelling play a central role in the nature of science, in its conduct, in the accreditation and dissemination of its outcomes, as well as forming a bridge to technology. They therefore have an important place in both the formal and informal science education provision made for people of all ages. This book is a product of five years collaborative work by eighteen researchers from four countries. It addresses four key issues: the roles of models in science and their implications for science education; the place of models in curricula for major science subjects; the ways that models can be presented to, are learned about, and can be produced by, individuals; the implications of all these for research and for science teacher education. The work draws on insights from the history and philosophy of science, cognitive psychology, sociology, linguistics, and classroom research, to establish what may be done and what is done. The book will be of interest to researchers in science education and to those taking courses of advanced study throughout the world. 404 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366298ISBN 13: 9780792366294
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the most important issues in the construction of future magnetic confinement fusion machines is that of the materials of which they are constructed, and one of the key points of proper material choice is the recycle of hydrogen isotopes with materials at the plasma face. Tritium machines demand high safety and economy, which in turn requires the lowest possible T inventory and smallest possible permeation through the plasma facing materials. The recycle behaviour of the in-vessel components must also be known if the plasma reaction is to predictable and controllable, and finally, the fuel cycle and plasma operating regimes may be actively controlled by special materials and methods. The book discusses both laboratory experiments exploring the basic properties of non-equilibrium hydrogen-solid systems (diffusion, absorption, boundary processes) and experimental results obtained from existing fusion machines under conditions simulating future situations to some extent. Contributions are from experts in the fields of nuclear fusion, materials science, surface science, vacuum science and technology, and solid state physics. 380 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792378849ISBN 13: 9780792378846
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is an up-to-date revision of the classic text first published in 1983. It includes a historical perspective on the growth of evaluation theory and practice and two comparative analyses of the various alternative perspectives on evaluation. It also includes articles representing the major schools of thought about evaluation written by the leaders who have developed these schools and models. The final section describes and discusses the Standards for Program Evaluation and the reformation of program evaluation. 524 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792365828ISBN 13: 9780792365822
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Coffee Biotechnology and Quality is a comprehensive volume containing 45 specialised chapters by internationally recognised experts. The book aims to provide a guide for those wishing to learn about recent advances in coffee cultivation and post-harvest technology. It provides a quantitative and rational approach to the major areas of coffee research, including breeding and cloning, tissue culture and genetics, pest control, post-harvest technology and bioconversion of coffee industry residues into commercially valuable products. The chapters review recent experimental work, allowing a conceptual framework for future research to be identified and developed. The book will be of interest to researchers and students involved in any area of coffee research. Consequently, plant breeders, microbiologists, biotechnologists and biochemical engineers will find the book to be a unique and invaluable guide. 564 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792366786ISBN 13: 9780792366782
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In recent years, the study of the plant cell cycle has become of major interest, not only to scientists working on cell division sensu strictu , but also to scientists dealing with plant hormones, development and environmental effects on growth. The book The Plant Cell Cycle is a very timely contribution to this exploding field. Outstanding contributors reviewed, not only knowledge on the most important classes of cell cycle regulators, but also summarized the various processes in which cell cycle control plays a pivotal role. The central role of the cell cycle makes this book an absolute must for plant molecular biologists. 256 pp. Englisch.
Editore: Springer Netherlands Nov 2000, 2000
ISBN 10: 0792387589ISBN 13: 9780792387589
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Libro Print on Demand
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The gastrointestinal tract has a number of unique features. Its extensive surface is formed by a single layer of rapidly renewing cells, the intestinal epithelial cells. These cells are in contact with a number of other cell populations, including the largest part of the immune system, and with an excessive luminal antigen load, including vast numbers of bacteria. Furthermore two more organs, namely liver and pancreas, are part of the system. The rapid renewal of the epithelial layer, the interactions of different cell types, and the balance between cell proliferation and death, have been fascinating subjects of studies in recent years. Much has been learned, and cytokines have emerged as important mediators for all these interactions and homeostatic systems. This book, the proceedings of the Falk Symposium 113 on `Cytokines and Cell Homeostasis in the Gastrointestinal Tract', held in Regensburg, Germany, 16-18 September 1999, provides a forum for basic scientists and interested clinicians to exchange ideas, to discuss concepts and to plan further studies. 432 pp. Englisch.