springer new york jun 2007 (24 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book charts the history of manned space stations in a logical, chronological order. It tells the story of the two major space powers starting out on their very separate programs, but slowly coming together. It describes rarely mentioned development programs, most of which never flew, including the US Manned Orbiting Laboratory, the Soviet Almaz station, and the Soviet Polyus battlestation. The Mir space station was one of the greatest human achievements in modern history, and a thorough telling of its story is essential to this book. This book is the first of its kind to tell the whole story of the manned space stations from the USA and Russia. 200 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This interdisciplinary book probes the subject of extraterrestrial intelligent life, offering scientific and technological implications, discussing the philosophical and religious connotations and rebuffing pseudo-scientific assertions such as 'rare earth'. The author discusses such philosophical questions as: What is intelligence What is consciousness Should we expect ETIs to be conscious beings Also discussed is the viability of future astronautics which would enable closer human contact with ETI. 316 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents a visionary concept for future development of space travel. It describes the enabling technology for future propulsion concepts and demonstrates how mankind will 'live off the land in space' in migration from Earth. For the next few millennia at least (barring breakthroughs), the human frontier will include the solar system and the nearest stars. Will it be better to settle the Moon, Mars, or a nearby asteroid and what environments can we expect to find in the vicinity of nearby stars These are questions that need to be answered if mankind is to migrate into space. 272 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 272 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -XI ACKNOWLEDGMENTS xiii INTRODUCTION XV CHAPTER 1: THE HISTORICAL AND PHILOSOPHICAL PERSPECTIVES 1 The Magical Vision of the Nonhuman 1 Ancient Philosophy 2 Medieval Philosophy 6 The Renaissance 8 The Birth of Modern Science 10 First Attempts at Contact 16 Cosmism 17 From Enthusiasm to Disenchantment 18 CHAPTER 2: THE RELIGIOUS PERSPECTIVE 23 Is Extraterrestrial Life a Threat to Religion 23 A Finite Universe and an Infinite God 25 Hinduism, Buddhism, and Other Oriental Religions 26 Judaism 27 Islam 28 Christianity 29 The Problem of Original Sin 30 The Problem of Redemption 34 Biocosmic Theology 36 Vll Contents CHAPTER 3: THE ASTROBIOLOGICAL PERSPECTIVE 41 A New Science: Astrobiology 41 Times of the Universe 43 The Anthropic Principle 47 Chemical Evolution 50 The Formation of the Solar System 51 The Formation of Extrasolar Planets 57 The Birth of Life on Earth 64 Panspermia 73 Evolution and Creationism 76 Toward a Great Complexity 81 Catastrophes and Mass Extinctions 86 Conditions Needed for the Development of Life 96 Life on Mars 107 Life in the Solar System 117 The Search for Life Outside the Solar System 123 CHAPTER 4: THE SEARCH FOR EXTRATERRESTRIAL INTELLIGENCE 129 Intelligence and Consciousness 129 Consciousness 133 The Development of Intelligence on Earth 137 From Intelligence to Technology 147 Evolution Beyond Humans 154 The Expansion of Intelligent Life 156 The Search for Intelligent Signals 164 The Pdo Scale 176 The Problem of the Answer 177 The San Marino Scale 180 Which Message 182 Extraterrestrials, How 187Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Human civilization has evolved to the point at which we can consider tapping space resources and expanding beyond Earth¿s atmosphere. The Introduction surveys possible motivations for large-scale human emigration to space. Since our early ancestors began to move out of Africa, humans have constantly expanded their range. Today, the pattern of human settlement extends from pole to pole. Humans regularly visit the upper troposphere and ocean floor and technology has enabled a few to even reside above the atmosphere in space stations.For the next few millennia at least (barring breakthroughs), the human frontier will include the solar system and the nearest stars. Will it better to settle the Moon, Mars, or a nearby asteroid and what environments can we expect to find in the vicinity of nearby stars are questions that need to be answered if mankind is to migrate into space.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intended for nonspecialists with some knowledge of physics or engineering, The Quantum Beat covers a wide range of salient topics relevant to atomic clocks, treated in a broad intuitive manner with a minimum of mathematical formalism. Detailed descriptions are given of the design principles of the rubidium, cesium, hydrogen maser, and mercury ion standards; the revolutionary changes that the advent of the laser has made possible, such as laser cooling, optical pumping, the formation of 'optical molasses,' and the cesium 'fountain' standard; and the time-based global navigation systems, Loran-C and the Global Positioning System. Also included are topics that bear on the precision and absolute accuracy of standards, such as noise, resonance line shape, the relativistic Doppler effect as well as more general relativistic notions of time relevant to synchronization of remote clocks, and time reversal symmetry.This edition retains the essentially didactic approach to the treatment of the development of atomic clocks in the first edition, but brings up to date the extraordinary developments in recent years, culminating in clocks based on quantum resonance at optical frequency in individual ions confined in miniature electromagnetic traps. These, together with advances in the generation of wide-band coherent frequency combs spanning the spectrum as far as the optical range, has made possible the direct measurement of phenomena occurring at optical frequencies! As a result of these recent advances, in addition to the time-based GPS and LORAN C navigation systems treated in the first edition, other important applications of a fundamental scientific interest have become feasible. These include satellite-borne tests of the theory of general relativity and the equivalence principle on which it is based. 492 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease, transplantation rejection, insulin resistance, multiple organ failure and cancer. TNF Receptor Associated Factors is the only literature that is entirely devoted to TRAFs. Almost every aspect of TRAF signaling is covered, including the different TRAF family members, their distinct biological functions, the TRAF structures, their modes of receptor recognition, the signaling mechanisms, and the roles of TRAFs in normal cellular functions and in viral infection. TNF Receptor Associated Factors is intended for a wide audience, including researchers in the field of TRAF signaling and students and postdoctoral fellows learning cell biology and cell signal transduction. This exciting new volume is up to date on the most recent advances in TRAF signal transduction. 206 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Environmental issues are growing in importance to the most important political, social, legal, and economic decisions. The book presents chemical analyses of our most pressing waste, pollution, and resource problems for the undergraduate or graduate student. The distinctive holistic approach provides both a solid ground in theory, as well as a laboratory manual detailing introductory and advanced experimental applications. The laboratory procedures are presented at microscale conditions, for minimum waste and maximum economy. This work fulfills an urgent need for an introductory text in environmental chemistry combining theory and practice, and is a valuable tool for preparing the next generation of environmental scientists. 334 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In their preface to the second edition of Test Equating, Scaling, and Linking, Mike Kolen and Bob Brennan (2004) made the following observation: 'Prior to 1980, the subject of equating was ignored by most people in the measurement community except for psychometricians, who had responsibility for equating' (p. vii). The authors went on to say that considerably more attention is now paid to equating, indeed to all forms of linkages between tests, and that this increased attention can be attributed to several factors: 1. An increase in the number and variety of testing programs that use multiple forms and the recognition among professionals that these multiple forms need to be linked. 2. Test developers and publishers, in response to critics, often refer to the role of linking in reporting scores. 3. The accountability movement and fairness issues related to assessment have become much more visible. Those of us who work in this field know that ensuring comparability of scores is not an easy thing to do. Nonetheless, our customers-the te- takers and score users-either assume that scores on different forms of an assessment can be used interchangeably or, like the critics above, ask us to justify our comparability assumptions. And they are right to do this. After all, the test scores that we provide have an impact on decisions that affect people's choices and their future plans. From an ethical point of view, we are obligated to get it right. 396 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the first English translation of Thomas Harriot's seminal Artis Analyticae Praxis, first published in Latin in 1631. It has recently become clear that Harriot's editor substantially rearranged the work, and omitted sections beyond his comprehension. Commentary included with this translation relates to corresponding pages in the manuscript papers, enabling exploration of Harriot's novel and advanced mathematics. This publication provides the basis for a reassessment of the development of algebra. 312 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Perturbation theory and in particular normal form theory has shown strong growth in recent decades. This book is a drastic revision of the first edition of the averaging book. The updated chapters represent new insights in averaging, in particular its relation with dynamical systems and the theory of normal forms. Also new are survey appendices on invariant manifolds. One of the most striking features of the book is the collection of examples, which range from the very simple to some that are elaborate, realistic, and of considerable practical importance. Most of them are presented in careful detail and are illustrated with illuminating diagrams. 460 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Probabilistic graphical models and decision graphs are powerful modeling tools for reasoning and decision making under uncertainty. As modeling languages they allow a natural specification of problem domains with inherent uncertainty, and from a computational perspective they support efficient algorithms for automatic construction and query answering. This includes belief updating, finding the most probable explanation for the observed evidence, detecting conflicts in the evidence entered into the network, determining optimal strategies, analyzing for relevance, and performing sensitivity analysis.The book introduces probabilistic graphical models and decision graphs, including Bayesian networks and influence diagrams. The reader is introduced to the two types of frameworks through examples and exercises, which also instruct the reader on how to build these models. The book is a new edition of Bayesian Networks and Decision Graphs by Finn V. Jensen. The new edition is structured into two parts. The first part focuses on probabilistic graphical models. Compared with the previous book, the new edition also includes a thorough description of recent extensions to the Bayesian network modeling language, advances in exact and approximate belief updating algorithms, and methods for learning both the structure and the parameters of a Bayesian network. The second part deals with decision graphs, and in addition to the frameworks described in the previous edition, it also introduces Markov decision processes and partially ordered decision problems. The authors also provide a well-founded practical introduction to Bayesian networks, object-oriented Bayesian networks, decision trees, influence diagrams (and variants hereof), and Markov decision processes.give practical advice on the construction of Bayesian networks, decision trees, and influence diagrams from domain knowledge.give several examples and exercises exploiting computer systems for dealing with Bayesian networks and decision graphs.present a thorough introduction to state-of-the-art solution and analysis algorithms.The book is intended as a textbook, but it can also be used for self-study and as a reference book. 447 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Intended for nonspecialists with some knowledge of physics or engineering, The Quantum Beat covers a wide range of salient topics relevant to atomic clocks, treated in a broad intuitive manner with a minimum of mathematical formalism. Detailed descriptions are given of the design principles of the rubidium, cesium, hydrogen maser, and mercury ion standards; the revolutionary changes that the advent of the laser has made possible, such as laser cooling, optical pumping, the formation of 'optical molasses,' and the cesium 'fountain' standard; and the time-based global navigation systems, Loran-C and the Global Positioning System. Also included are topics that bear on the precision and absolute accuracy of standards, such as noise, resonance line shape, the relativistic Doppler effect as well as more general relativistic notions of time relevant to synchronization of remote clocks, and time reversal symmetry.This edition retains the essentially didactic approach to the treatment of the development of atomic clocks in the first edition, but brings up to date the extraordinary developments in recent years, culminating in clocks based on quantum resonance at optical frequency in individual ions confined in miniature electromagnetic traps. These, together with advances in the generation of wide-band coherent frequency combs spanning the spectrum as far as the optical range, has made possible the direct measurement of phenomena occurring at optical frequencies! As a result of these recent advances, in addition to the time-based GPS and LORAN C navigation systems treated in the first edition, other important applications of a fundamental scientific interest have become feasible. These include satellite-borne tests of the theory of general relativity and the equivalence principle on which it is based.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 492 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the term 'random eld'' has a variety of different connotations, ranging from agriculture to statistical mechanics, let us start by clarifying that, in this book, a random eld is a stochastic process, usually taking values in a Euclidean space, and de ned over a parameter space of dimensionality at least 1. Consequently, random processes de ned on countable parameter spaces will not 1 appear here. Indeed, even processes on R will make only rare appearances and, from the point of view of this book, are almost trivial. The parameter spaces we like best are manifolds, although for much of the time we shall require no more than that they be pseudometric spaces. With this clari cation in hand, the next thing that you should know is that this book will have a sequel dealing primarily with applications. In fact, as we complete this book, we have already started, together with KW (Keith Worsley), on a companion volume [8] tentatively entitled RFG-A,or Random Fields and Geometry: Applications. The current volume-RFG-concentrates on the theory and mathematical background of random elds, while RFG-A is intended to do precisely what its title promises. Once the companion volume is published, you will nd there not only applications of the theory of this book, but of (smooth) random elds in general. 472 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. This book attempts to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. It explores insulin action at the most basic levels, through complex systems. 232 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. It covers the entire semaphorin field from neurosciences to cardiovascular research and beyond, detailing all the latest techniques and results. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems. 147 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -More than 18 million people in the United States have diabetes mellitus, and about 90% of these have the type 2 form of the disease. In addition, between 17 and 40 million people have insulin resistance, impaired glucose tolerance, or the cluster of abnormalities referred to variably as the metabolic syndrome, the dysmetabolic syndrome, syndrome X, or the insulin resistance syndrome. In all of these disorders, a central component of the pathophysiology is insulin resistance, i.e., reduced responsiveness to insulin in tissues such as muscle, fat and liver. Insulin resistance is also closely linked to other common health problems, including obesity, polycystic ovarian disease, hyperlipidemia, hypertension, and atherosclerosis. In this book, we will attempt to dissect the complexity of the molecular mechanisms of insulin action with a special emphasis on those features of the system that are subject to alteration in type 2 diabetes and other insulin resistant states. We explore insulin action at the most basic levels, through complex systems. The book will be appealing to basic and clinical scientists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 232 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text provides an overview of the processes of brain death, exploring the concepts and historical approach of human death, clinical examinations of brain-dead patients, ancillary tests in coma and brain death, bioethical discussions of brain death and its relationship with some consciousness disturbances, and the legal considerations of human death. Unlike other, narrow-focus reference this book encompasses a wide spectrum of issues including medical, legal, bioethical and historical aspects. 248 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration. The chapters are organized such that useful decision trees are included together with the scientific underpinning for their application. In addition, trends in the use of solvent systems and a balance of current views make this monograph useful to both the novice and experienced researcher and to scientists at all developmental stages from early discovery to late pharmaceutical operations. 480 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Recent developments in regional and systemic anticancer therapies have improved the grim outlook of patients with peritoneal carcinomatosis (PC) from ovarian or gastrointestinal origin, leading to a renewed interest in both the underlying mechanisms at the origin of PC and the various therapeutic options.This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Peritoneal Carcinomatosis: A Multidisciplinary Approach will be of interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC, as well as for basic and translational scientists active in the field of locoregional cancer spread. Numerous illustrations aid the reader throughout in the many facets of this disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 568 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This text is intended to provide an overview of brain death. The topics explored in this book are the concept and historical approach of human death, clinical examinations of brain-dead patients, ancillary tests in coma and brain death, bioethical discussions of brain death and its relationship with some consciousness disturbances, and the legal considerations of human death.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration. The chapters are organized such that useful decision trees are included together with the scientific underpinning for their application. In addition, trends in the use of solvent systems and a balance of current views make this monograph useful to both the novice and experienced researcher and to scientists at all developmental stages from early discovery to late pharmaceutical operations.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 480 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The last three decades have witnessed enormous progress in the care of patients with congenital heart disease. Treatment of congenital heart disease is highly dependent on technology and much of the progress we have witnessed is attrib utable to technological advances we take almost for granted today. It would be difficult to overestimate the impact of these advances; noteworthy examples include the development of 2-D Doppler echocardiography resulting in increased diagnostic accuracy, improvements in preoperative management including the use of prostaglandins for maintaining ductal patency, better intraoperative support such as the development of cardiopulmonary bypass circuits specifically designed for neonates and infants and improvements in postoperative care too numerous to delineate. As the spectrum of congenital heart disease we can treat successfully has broadened and the results have improved much of the focus has shifted, properly, to long-term issues such as neurodevelopmental outcome and quality of life. Despite the current focus on long-term outcomes we must not forget that surgery is central to our treatment strategy. The word technology is derived from the Greek word 'techne' meaning craft and before any late out comes can be measured the 'craft' of surgery must be performed with excellence. Dr. Litwin's career has spanned these last three decades and he has witnessed and participated in the evolution of congenital heart surgery. The second edition of a 'Color Atlas of Congenital Heart Surgery' is an outstanding contribution to the field by a master of the craft of congenital heart surgery. 479 pp. Englisch.