Springer new york okt 2016 (243 risultati)

Taschenbuch. Condizione: Neu. Neuware -Hunter-gatherer research has played a historically central role in the development of anthropological and evolutionary theory. Today, research in this traditional and enduringly vital field blurs lines of distinction between archaeology and ethnology, and seeks instead to develop perspectives and theories broadly applicable to anthropology and its many sub disciplines.In the groundbreaking first edition of Hunter-Gatherers: Archaeological and Evolutionary Theory (1991), Robert Bettinger presented an integrative perspective on hunter-gatherer research and advanced a theoretical approach compatible with both traditional anthropological and contemporary evolutionary theories.Hunter-Gatherers remains a well-respected and much-cited text, now over 20 years since initial publication. Yet, as in other vibrant fields of study, the last two decades have seen important empirical and theoretical advances.In this second edition of Hunter-Gatherers, co-authors Robert Bettinger, Raven Garvey, and Shannon Tushingham offer a revised and expanded version of the classic text, which includes a succinct and provocative critical synthesis of hunter-gatherer and evolutionary theory, from the Enlightenment to the present. New and expanded sections relate and react to recent developments¿some of them the authors¿ own¿particularly in the realms of optimal foraging and cultural transmission theories.An exceptionally informative and ambitious volume on cultural evolutionary theory, Hunter-Gatherers, second edition, is an essential addition to the libraries of anthropologists, archaeologists, and human ecologists alike.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book recounts the epic saga of how we as human beings have come to understand the Solar System. The story of our exploration of the heavens, Peter Bond reminds us, began thousands of years ago, with the naked-eye observations of the earliest scientists and philosophers. Over the centuries, as our knowledge and understanding inexorably broadened and deepened, we faltered many times, frequently labored under misconceptions, and faced seemingly insurmountable obstacles to understanding. Yet, despite overwhelming obstacles, a combination of determined observers, brilliant thinkers, courageous explorers, scientists and engineers has brought us, particularly over the last five decades, into a second great age of human discovery.At our present level of understanding, some fifty years into the Space Age, the sheer volume of images and other data being returned to us from space has only increased our appetite for more and more detailed information about the planets, moons, asteroids, and comets of the Solar System. Taking a much-needed overview of how we now understand these 'distant worlds' in our cosmic neighborhood, Bond not only celebrates the extraordinary successes of planetary exploration, but reaffirms an important truth: For seekers of knowledge, there will always be more to explore.An astonishing saga of exploration.In this much-needed overview of 'where we stand today,' Peter Bond describes the achievements of the astronomers, space scientists, and engineers who have made the exploration of our Solar System possible. A clearly written and compelling account of the Space Age, the book includes:- Dramatic accounts of the daring, resourcefulness, and ferocious competitive zeal of renowned as well as almost-forgotten space pioneers.- Clear explanations of the precursors to modern astronomy, including how ancient natural philosophers and observers first took the measure of the heavens.- More than a hundred informative photographs, maps, simulated scenarios, and technical illustrations--many of them in full color.- Information-dense appendices on the physical properties of our Solar System, as well as a comprehensive list of 50 years of Solar System missions.Organized into twelve chapters focused on the objects of our exploration (the individual planets, our Moon, the asteroids and comets), Bond's text shows how the great human enterprise of space exploration may on occasion have faltered or wandered off the path, but taken as a whole amounts to one of the great triumphs of human civilization. 340 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Newspaper columns blare the news daily. There is no doubt that we are struggling through a worldwide economic and financial crisis of a magnitude not witnessed since the Great Depression.In this environment, fraught with danger, no company can afford to take a wait-and-see attitude. One hesitation or misstep can result in the rapid demise of a once stalwart enterprise. Even small miscalculations can topple mighty empires; consider the U.S. auto industry, for example. The severity of the crisis demands that your company understand its causes, diagnose carefully, implement decisively and monitor constantly.However, the crisis also creates chances for companies that learn to assess risk, recognize opportunity and take action quickly. This book is an antidote to the chorus of doom-and-gloom, a manual for business leaders and employees who are ready to fight. In Beat the Crisis, international strategy guru, Hermann Simon, offers 33 practical actions that any company can take immediately. Organized into broad categories-'Changing Customer Needs,' 'Sales and the Sales Force,' 'Managing Offers and Prices' and 'Services'-Simon shows companies how to focus on the areas where emphatic action can have quick and maximum impact on corporate performance. Drawing from dozens of successful cases around the world, Simon helps readers learn to read the market signals, develop quick solutions, and stay a step ahead of their competitors, while avoiding the pitfalls looming in the crisis. A concluding chapter looks beyond the crisis and considers the longer-term socio-political and business consequences, in which Simon foresees a new era of restraint. 172 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This lively introductory text exposes the student to the rewards of a rigorous study of functions of a real variable. In each chapter, informal discussions of questions that give analysis its inherent fascination are followed by precise, but not overly formal, developments of the techniques needed to make sense of them. By focusing on the unifying themes of approximation and the resolution of paradoxes that arise in the transition from the finite to the infinite, the text turns what could be a daunting cascade of definitions and theorems into a coherent and engaging progression of ideas. Acutely aware of the need for rigor, the student is much better prepared to understand what constitutes a proper mathematical proof and how to write one.Fifteen years of classroom experience with the first edition of Understanding Analysis have solidified and refined the central narrative of the second edition. Roughly 150 new exercises join a selection of the best exercises fromthe first edition, and three more project-style sections have been added. Investigations of Euler's computation of zeta(2), the Weierstrass Approximation Theorem, and the gamma function are now among the book's cohort of seminal results serving as motivation and payoff for the beginning student to master the methods of analysis. 324 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents applications of geometric optimal control to real life biomedical problems with an emphasis on cancer treatments. A number of mathematical models for both classical and novel cancer treatments are presented as optimal control problems with the goal of constructing optimal protocols. The power of geometric methods is illustrated with fully worked out complete global solutions to these mathematically challenging problems. Elaborate constructions of optimal controls and corresponding system responses provide great examples of applications of the tools of geometric optimal control and the outcomes aid the design of simpler, practically realizable suboptimal protocols. The book blends mathematical rigor with practically important topics in an easily readable tutorial style. Graduate students and researchers in science and engineering, particularly biomathematics and more mathematical aspects of biomedical engineering, would find this book particularly useful. 516 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a collection of chapters covering the latest developments in applications of financial mathematics and statistics to topics in energy, commodity financial markets and environmental economics. The research presented is based on the presentations and discussions that took place during the Fields Institute Focus Program on Commodities, Energy and Environmental Finance in August 2013. The authors include applied mathematicians, economists and industry practitioners, providing for a multi-disciplinary spectrum of perspectives on the subject. The volume consists of four sections: Electricity Markets; Real Options; Trading in Commodity Markets; and Oligopolistic Models for Energy Production. Taken together, the chapters give a comprehensive summary of the current state of the art in quantitative analysis of commodities and energy finance. The topics covered include structural models of electricity markets, financialization of commodities, valuation of commodity real options, game-theory analysis of exhaustible resource management and analysis of commodity ETFs. The volume also includes two survey articles that provide a source for new researchers interested in getting into these topics. 444 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph treats the classical theory of quadratic Diophantine equations and guides the reader through the last two decades of computational techniques and progress in the area. These new techniques combined with the latest increases in computational power shed new light on important open problems. The authors motivate the study of quadratic Diophantine equations with excellent examples, open problems and applications. Moreover, the exposition aptly demonstrates many applications of results and techniques from the study of Pell-type equations to other problems in number theory.The book is intended for advanced undergraduate and graduate students as well as researchers. It challenges the reader to apply not only specific techniques and strategies, but also to employ methods and tools from other areas of mathematics, such as algebra and analysis. 232 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book explores the unique relationships between professional baseball teams and the unique ways professional baseball leagues are organized in North America with a primary focus on how proximity can and does impact consumer demand. Perhaps more than any other matter that arises in the business of baseball, proximity to other professional baseball teams is a concern that has uniquely shaped professional baseball leagues in North America. It is this particular component in how professional baseball leagues are organized that suggests building a proximity-based approach to studying the economics of minor league baseball. This book opens up new ways to study minor league baseball, specifically, and sports leagues more generally. So even as advanced technology has eliminated some of the need for fans to be in close proximity to the teams they love to follow, there is still a need to understand more completely how proximity matters can impact the way professional baseball leagues are structured and how that structure can ultimately impact the quality of the games that entertain sports fans everywhere. This book will be of interest to both sports economists and practitioners. 144 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book examines hybrid tribunals created in Sierra Leone, Kosovo, Cambodia, East Timor, and Lebanon, in terms of their origins (the political and social forces that led to their creation), the legal regimes that they used, their various institutional structures, and the challenges that they faced during their operations. Through this study, the author looks at both their successes and their shortcomings, and presents recommendations for the formation of future hybrid tribunals.Hybrid tribunals are a form of the international justice where the judicial responsibility is shared between the international community and the local state where they function. These tribunals represent an important bridge between traditional international courts like the International Criminal Court (ICC), the International Criminal Tribunal for the Former Yugoslavia (ICTY), the International Criminal Tribunal for Rwanda (ICTR) and various local justice systems. Because hybrid tribunals are developed in response to large-scale atrocities, these courts are properly considered part of the international criminal justice system. This feature gives hybrid tribunals the accountability and legitimacy often lost in local justice systems; however, by including regional courtroom procedures and personnel, they are integrated into the local justice system in a way that allows a society to deal with its criminals on its own terms, at least in part.This unique volume combines historical and legal analyses of these hybrid tribunals, placing them within a larger historical, political, and legal context. It will be of interest to researchers in Criminal Justice, International Studies, International Law, and related fields. 224 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is a concise yet comprehensive resource for physicians dealing with, and interested in, the field of molecular pathology in dermatopathology. The book includes descriptions of the techniques and their application to cutaneous diseases and describes possible future techniques and their use in dermatopathology. Special emphasis is also given to the practical application of these techniques to particular situations illustrated by demonstrative cases.Written by experts in their fields, Precision Molecular Pathology of Dermatologic Diseases is of great value to pathologists, dermatologists, resident and fellows, internists, and general practitioners who deal with dermatologic diseases. 144 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a unique selection of work by world-class experts exploring the latest developments in Hamiltonian partial differential equations and their applications. Topics covered within are representative of the field's wide scope, including KAM and normal form theories, perturbation and variational methods, integrable systems, stability of nonlinear solutions as well as applications to cosmology, fluid mechanics and water waves.The volume contains both surveys and original research papers and gives a concise overview of the above topics, with results ranging from mathematical modeling to rigorous analysis and numerical simulation. It will be of particular interest to graduate students as well as researchers in mathematics and physics, who wish to learn more about the powerful and elegant analytical techniques for Hamiltonian partial differential equations. 464 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The second edition of this volume provides novel protocols for the study of newly discovered function and modifications of components of the Hh pathways. The first few chapters discuss methods for stable delivery of soluble Hh proteins in cell cultures that can be adapted for in vivo studies, and mathematical models for studying Hh proteins gradient formation in tissues. The next few chapters explore studies in cell culture using fibroblasts that respond readily to Hh proteins. The book goes on to present protocols for evaluation of transcriptional activity of the Gli transcription factors in cell cultures and determine the expression level of endogenous Gli proteins. The final chapters talk about metabolic effects of noncanonical Hh signaling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, Hedgehog Signaling Protocols, Second Edition presents researchers with a comprehensive understanding of the Hh pathway and its function in development and diseases. 216 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a systematic presentation of the principles and practices behind the synthesis and functionalization of graphene and grapheme oxide (GO), as well as the fabrication techniques for transparent conductors from these materials.Transparent conductors are used in a wide variety of photoelectronic and photovoltaic devices, such as liquid crystal displays (LCDs), solar cells, optical communication devices, and solid-state lighting. Thin films made from indium tin oxide (ITO) have thus far been the dominant source of transparent conductors, and now account for 50% of indium consumption. However, the price of Indium has increased 1000% in the last 10 years. Graphene, a two-dimensional monolayer of sp2-bonded carbon atoms, has attracted significant interest because of its unique transport properties. Because of their high optical transmittance and electrical conductivity, thin film electrodes made from graphene nanosheets have been considered an ideal candidate to replace expensive ITO films.Graphene for Transparent Conductors offers a systematic presentation of the principles, theories and technical practices behind the structure-property relationship of the thin films, which are the key to the successful development of high-performance transparent conductors. At the same time, the unique perspectives provided in the applications of graphene and GO as transparent conductors will serve as a general guide to the design and fabrication of thin film materials for specific applications. 236 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume focuses on cytological, biochemical, and molecular biological methods to identify and examine the function of each nuclear body, with an emphasis on the analysis of long non-coding RNAs. Chapters focus on exploring recent studies that reveal how certain long non protein-coding RNAs accumulate in specific nuclear bodies and regulate the function of the bodies by serving as architectural components or controlling the dynamics of associating protein components. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Nuclear Bodies and Noncoding RNAs: Methods and Protocols serves as a guideline for further study into the sophisticated regulation of gene expression. 364 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is the most up-to-date text available on diffuse malignant mesothelioma and includes all the newest imaging modalities, immunohistochemical features, and ever-expanding information on the molecular characteristics of the cancer. In-depth chapters contain fully referenced text as well as detailed tables and images. While the primary audiences for this book are pathologists and pathology residents, the broad examination of diffuse malignant mesothelioma, including its epidemiology, makes this book valuable to radiologists, surgeons, oncologists, and other clinical physicians and their residents as well.Written by experts in the field, Diffuse Malignant Mesothelioma is a concise yet comprehensive resource for clinicians involved in the management of one of the most widely recognized and feared cancers in the world. 156 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a theoretical background of branching processes and discusses their biological applications. Branching processes are a well-developed and powerful set of tools in the field of applied probability. The range of applications considered includes molecular biology, cellular biology, human evolution and medicine. The branching processes discussed include Galton-Watson, Markov, Bellman-Harris, Multitype, and General Processes. As an aid to understanding specific examples, two introductory chapters, and two glossaries are included that provide background material in mathematics and in biology. The book will be of interest to scientists who work in quantitative modeling of biological systems, particularly probabilists, mathematical biologists, biostatisticians, cell biologists, molecular biologists, and bioinformaticians. The authors are a mathematician and cell biologist who have collaborated for more than a decade in the field of branching processes in biology for this new edition.This second expanded edition adds new material published during the last decade, with nearly 200 new references. More material has been added on infinitely-dimensional multitype processes, including the infinitely-dimensional linear-fractional case. Hypergeometric function treatment of the special case of the Griffiths-Pakes infinite allele branching process has also been added. There are additional applications of recent molecular processes and connections with systems biology are explored, and a new chapter on genealogies of branching processes and their applications.Reviews of First Edition:'This is a significant book on applications of branching processes in biology, and it is highly recommended for those readers who are interested in the application and development of stochastic models, particularly those with interests in cellular and molecular biology.' (Siam Review, Vol. 45 (2), 2003)'This book will be very interesting and useful for mathematicians, statisticians and biologists as well, and especially for researchers developing mathematical methods in biology, medicine and other natural sciences.' (Short Book Reviews of the ISI, Vol. 23 (2), 2003) 300 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware - The text provides the general pathologist, clinician and pulmonary pathologist with a framework on how to work up a case of either non neoplastic or neoplastic lung disease and provide clinically relevant information to all involved in patient care. The basic understanding of radiologic findings and what they mean or how they are related to clinical and pathologic findings is addressed in detail. The implications of descriptive and diagnostic terms as well as the criteria for diagnosis and limitations of small biopsies is explained. The new entities in lung pathology whether neoplastic or non neoplastic are defined and characterized. The special techniques of pulmonary cytopathology, immunohistochemistry and molecular testing are outlined and specific algorithms for using them defined. Diagnosis of Small Lung Biopsy: An Integrated Approach will serve as a very useful resource for practicing pathologists, clinicians and those in training with interest in pulmonary pathology and pulmonary medicine. 120 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Agreat deal is known about how infants form attachments, and how these processes carry over into adolescence. But after that, the trail grows cold: the study of adult attachment emphasizes individual variations, paying little attention to the normative mechanisms of adult bonding.A much-needed corrective, Bases of Adult Attachment examines this under-investigated topic with an eye toward creating a robust theoretical model. The first volume of its kind, its multilevel approach integrates current findings from neuroscience and psychology to analyze the processes by which adult relationships develop, mature, function and dissolve. Here in relevant detail are factors contributing to initial attraction, possible scenarios in the evolution from friendship to attachment and the changes that occur on both sides of a relationship as partners mutually influence each other's behavior, emotions, cognition and even physiology. And expert contributors address long-neglected questions in the field with stimulating topics such as:The distress-relief dynamic in attachment bonding.An expectancy-value approach to attachment.The biobehavioral legacy of early attachment relationships for adult emotional and interpersonal functioning.How early experiences shape attraction, partner preferences, and attachment dynamics.How mental representations change as attachments form.Insights into the formation of attachment bonds from a social network perspective.Bases of Adult Attachment will interest scholars approaching adult attachment at multiple levels of analysis (neural, physiological, affective, cognitive and behavioral) and from multiple perspectives. This wide audience includes developmental, social and cognitive psychologists as well as neuroscientists, neuropsychologists, clinicians, sociologists, family researchers and professionals in public health and medicine. 212 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intriguing new findings on how genes and environments work together through different stages of life take the spotlight in this significant collection. Studies from infancy to late adulthood show both forces as shaping individuals' relationships within family and non-family contexts, and examine how these relationships, in turn, continue to shape the individual. Transitional periods, in which individuals become more autonomous and relationships and personal identities become more complicated, receive special emphasis. In addition, chapters shed light on the extent to which the quantity and quality of genetic and environmental influence may shift across and even within life stages.Included in the coverage:Gene-environment interplay in parenting young children.The sibling relationship as a source of shared environment.Gene-environment transactions in childhood and adolescent problematic peer relationships.Toward a developmentally sensitive and genetically informed perspective on popularity.Spouse, parent, and co-worker: roles and relationships in adulthood.The family system as a unit of clinical care: the role of genetic systems.Behavioral geneticists, clinical psychologists, and family therapists will find in Gene-Environment Interplay in Interpersonal Relationships across the Lifespan a window into current thinking on the subject, new perspectives for understanding clients and cases, and ideas for further study. 296 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This timely text overviews theories, concepts, and contexts relating to the emerging field of behavioral economics. Research theories and data gathered across psychology, sociology, marketing, finance, and other relevant disciplines are synthesized to identify and elaborate on the defining aspects of consumer economic wellbeing. Against a background of consumer rights and responsibilities, the book discusses consumer phenomena of earning, spending, saving, and borrowing and their contributions to improving (and in some cases to worsening) economic wellness. In addition, the author presents effective ways consumers can be encouraged to navigate key economic environments such as the media, advertising, and the internet, and to change negative financial behaviors.Among the featured topics:Historical perspective on consumer economic wellbeing.Consumer financial capability and economic wellbeing.The role of government in promoting consumer economic wellbeing.Corporate social responsibility.Theories of online shopping and e-banking.Desirable and undesirable consumption behavior.Consumer Economic Wellbeingclarifies issues and provides insights for researchers in the fields of consumer psychology and economics, psychologists and mental health professionals, and policy analysts. It is also useful as a text for college courses in related subjects. 240 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Hunter-gatherer research has played a historically central role in the development of anthropological and evolutionary theory. Today, research in this traditional and enduringly vital field blurs lines of distinction between archaeology and ethnology, and seeks instead to develop perspectives and theories broadly applicable to anthropology and its many sub disciplines. In the groundbreaking first edition of Hunter-Gatherers: Archaeological and Evolutionary Theory (1991), Robert Bettinger presented an integrative perspective on hunter-gatherer research and advanced a theoretical approach compatible with both traditional anthropological and contemporary evolutionary theories.Hunter-Gatherers remains a well-respected and much-cited text, now over 20 years since initial publication. Yet, as in other vibrant fields of study, the last two decades have seen important empirical and theoretical advances. In this second edition of Hunter-Gatherers, co-authors Robert Bettinger, Raven Garvey, and Shannon Tushingham offer a revised and expanded version of the classic text, which includes a succinct and provocative critical synthesis of hunter-gatherer and evolutionary theory, from the Enlightenment to the present. New and expanded sections relate and react to recent developments-some of them the authors' own-particularly in the realms of optimal foraging and cultural transmission theories.An exceptionally informative and ambitious volume on cultural evolutionary theory, Hunter-Gatherers, second edition, is an essential addition to the libraries of anthropologists, archaeologists, and human ecologists alike. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Hunter-gatherer research has played a historically central role in the development of anthropological and evolutionary theory. Today, research in this traditional and enduringly vital field blurs lines of distinction between archaeology and ethnology, and seeks instead to develop perspectives and theories broadly applicable to anthropology and its many sub disciplines. In the groundbreaking first edition of Hunter-Gatherers: Archaeological and Evolutionary Theory (1991), Robert Bettinger presented an integrative perspective on hunter-gatherer research and advanced a theoretical approach compatible with both traditional anthropological and contemporary evolutionary theories.Hunter-Gatherers remains a well-respected and much-cited text, now over 20 years since initial publication. Yet, as in other vibrant fields of study, the last two decades have seen important empirical and theoretical advances. In this second edition of Hunter-Gatherers, co-authors Robert Bettinger, Raven Garvey, and Shannon Tushingham offer a revised and expanded version of the classic text, which includes a succinct and provocative critical synthesis of hunter-gatherer and evolutionary theory, from the Enlightenment to the present. New and expanded sections relate and react to recent developments-some of them the authors' own-particularly in the realms of optimal foraging and cultural transmission theories.An exceptionally informative and ambitious volume on cultural evolutionary theory, Hunter-Gatherers, second edition, is an essential addition to the libraries of anthropologists, archaeologists, and human ecologists alike. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, Designer Receptors Exclusively Activated by Designer Drugs aims to ensure successful results in the further study of this vital field. 180 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues. With sections covering the role of radiation therapy in the various pelvic malignancies, the pathophysiology of radiation related injury and the risk factors that increase the possibility of such an injury, and the latest in medical, endoscopic and surgical therapies for these radiation related complications the text offers a concise yet comprehensive overview of radiation therapy in the human pelvis, its role and the adverse effects on the pelvic organs. Written by experts in the field with readers in mind, Radiation Therapy for Pelvic Malignancy and its Consequences is the first of its kind standalone reference on the subject. Radiation Therapy for Pelvic Malignancy and its Consequences is of great value to urologists, medical radiation and gynecological oncologists, and gastroenterologists. 244 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This direct, accessible guide uses a human rights perspective to define effectiveness in aid delivery and offer a robust framework for creating sustainable health programs and projects and assessing their progress. Geared toward hands-on professionals in such critical areas as food aid, maternal health, and disease control, it lays out challenges and solutions related to funding, planning, and complexity as individual projects feed into and impact larger health and development systems. Contributors clarify optimum roles of government, academia, NGOs, community organizations, and the private sector in aid delivery to inspire readers' broader and deeper uses of teamwork, communication, and imagination. Throughout, the guiding principles of justice, equity, and respect that underlie foundational documents such as the Millennium Declaration inform this visionary work. Included in the coverage: Assessing the effectiveness of health projects.Scaling-up of high-impact interventions.Aid effectiveness and private sector health organizations.When charity destroys dignity and sustainability.Effective conversations in global health projects.Lessons from the field on sustainability and effectiveness. For professionals in global health and development, Aid Effectiveness in Global Health is a trusted and encouraging mentor. This volume gives its readers the necessary logistical and attitudinal tools to bring about lasting change, and shows how to use them meaningfully in both the short term and the long run. 388 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature.Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice. 280 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents cutting-edge techniques to design, fabricate and use compartmentalized microfluidic devices. Chapters encompass axon guidance and manipulation, compartmentalized devices for synapse manipulation, cell populations interaction either in physiological or pathological condition and compartmentalized devices for pharmacological research and drug discovery. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.Authoritative and practical, Microfluidic and Compartmentalized Platforms for Neurobiological Research provides practical skills needed to fabricate, use microfluidics and compartmentalized platforms with neuronal cell cultures as well as the strengths of these exciting devices and their precious contribution in the field of Neuroscience. 264 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume summarizes current cutting-edge methods related to carbohydrate-based vaccines, from the identification of a suitable carbohydrate antigen via the preparation of glycoconjugate vaccines to the characterization of vaccine candidates for their use in pre-clinical and clinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Carbohydrate-Based Vaccines: Methods and Protocols aims to be a valuable manual that will facilitate research in the field of carbohydrate-based vaccines. 268 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The new edition of this influential textbook, geared towards graduate or advanced undergraduate students, teaches the statistics necessary for financial engineering. In doing so, it illustrates concepts using financial markets and economic data, R Labs with real-data exercises, and graphical and analytic methods for modeling and diagnosing modeling errors. These methods are critical because financial engineers now have access to enormous quantities of data. To make use of this data, the powerful methods in this book for working with quantitative information, particularly about volatility and risks, are essential. Strengths of this fully-revised edition include major additions to the R code and the advanced topics covered. Individual chapters cover, among other topics, multivariate distributions, copulas, Bayesian computations, risk management, and cointegration. Suggested prerequisites are basic knowledge of statistics and probability, matrices and linear algebra, and calculus. There is an appendix on probability, statistics and linear algebra. Practicing financial engineers will also find this book of interest. 748 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides a comprehensive overview of quality metrics and methods used to improve quality for all major modalities of CRC screening. It introduces the readers to the evidence of effectiveness behind various CRC screening modalities: stool-based tests (Fecal Occult Blood, Fecal Immunochemical and Fecal DNA tests), flexible sigmoidoscopy, colonoscopy and CT colonography. In-depth chapters review the latest guidelines for CRC screening, compare differences among the five major national guidelines, and highlight the need for valid quality and cost indicators. While the main focus of this volume is on colonoscopy, since most quality indicators and analyses have focused on this modality of screening and surveillance, one chapter is devoted to quality indicators of other screening modalities. Differences between process and outcome measures are also highlighted and a small but valid set of recommended national measures are listed.Written by experts in the field, Colorectal Cancer Screening: Quality and Benchmarks is an important and useful resource written for gastroenterologists, primary care physicians, general and colorectal surgeons, family physicians, and investigators with research focus in screening and quality metrics. 220 pp. Englisch.…