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  • Frank Yiannas

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493924885 ISBN 13: 9781493924882

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This book helps in Achieving food safety success which requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of the human dimensions of food safety. In the field of food safety today, much is documented about specific microbes, time/temperature processes, post-process contamination, and HACCP¿things often called the hard sciences. There is not much published or discussed related to human behavior¿often referred to as the ¿soft stuff.¿ However, looking at foodborne disease trends over the past few decades and published regulatory out-of-compliance rates of food safety risk factors, it¿s clear that the soft stuff is still the hard stuff. Despite the fact that thousands of employees have been trained in food safety around the world, millions have been spent globally on food safety research, and countless inspections and tests have been performed at home and abroad, food safety remains a significant public health challenge. Why is that Because to improve food safety, we must realize that it¿s more than just food science; it¿s the behavioral sciences, too. In fact, simply put, food safety equals behavior. This is the fundamental principle of this book. If you are trying to improve the food safety performance of a retail or food service establishment, an organization with thousands of employees, or a local community, what you are really trying to do is change people¿s behavior. The ability to influence human behavior is well documented in the behavioral and social sciences. However, significant contributions to the scientific literature in the field of food safety are noticeably absent. This book will help advance the science by being the first significant collection of 50 proven behavioral science techniques, and be the first to show how these techniques can be applied to enhance employee compliance with desired food safety behaviors and make food safety the socialnorm in any organization.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 132 pp. Englisch.

  • Andrew Cochrane

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493926543 ISBN 13: 9781493926541

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -This volume presents a collection of interdisciplinary collaborations between contemporary art, heritage, anthropological, and archaeological practitioners. Departing from the proceedings of the Sixth World Archaeological Congress¿s ¿Archaeologies of Art¿ theme and Ábhar agus Meon exhibitions, it includes papers by seminal figures as well as experimental work by those who are exploring the application of artistic methods and theory to the practice of archaeology. Art and archaeology: collaborations, conversations, criticisms encourages the creative interplay of various approaches to ¿art¿ and ¿archaeology¿ so these new modes of expression can contribute to how we understand the world. Established topics such as cave art, monumental architecture and land art will be discussed alongside contemporary video art, performance art and relational arts practices. Here, the parallel roles of artists as makers of new worlds and archaeologists as makers of pasts worlds are brought together to understand the influences of human creativity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.

  • Guangpu Li

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493925687 ISBN 13: 9781493925681

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This volume covers the latest technological advances in the characterization of the biosynthesis and functions of Rab GTPases and their regulation by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The book consists of 28 chapters and starts with an overview of the Rab GTPase family. The next few chapters describe systematic approaches to the identification and classification of Rabs and Rab GAPs, as well as the detection of Rab isoprenylation and membrane distribution. The last few chapters examine the biochemical and functional properties of individual Rabs in the order of exocytic, recycling and endocytic Rabs. Written in the highly successfulMethods of Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls.Instructive and practical,Rab GTPases: Methods and Protocolsapproaches each topic with great detail and is a valuable resource for researchers and students interested in the field of Rab GTPases.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 376 pp. Englisch.

  • Donna L. Gillette

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493926799 ISBN 13: 9781493926794

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -Social and behavioral scientists study religion or spirituality in various ways and have defined and approached the subject from different perspectives. In cultural anthropology and archaeology the understanding of what constitutes religion involves beliefs, oral traditions, practices and rituals, as well as the related material culture including artifacts, landscapes, structural features and visual representations like rock art. Researchers work to understand religious thoughts and actions that prompted their creation distinct from those created for economic, political, or social purposes. Rock art landscapes convey knowledge about sacred and spiritual ecology from generation to generation.Contributors to this global view detail how rock art can be employed to address issues regarding past dynamic interplays of religions and spiritual elements. Studies from a number of different cultural areas and time periods explore how rock art engages the emotions, materializes thoughts and actions and reflects religious organization as it intersects with sociopolitical cultural systems.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

  • Diane Dallal

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489997512 ISBN 13: 9781489997517

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -Historical Archaeology of New York City is a collection of narratives about people who lived in New York City during the seventeenth, eighteenth, and nineteenth centuries, people whose lives archaeologists have encountered during excavations at sites where these people lived or worked. The stories are ethnohistorical or microhistorical studies created using archaeological and documentary data. As microhistories, they are concerned with particular people living at particular times in the past within the framework of world events. The world events framework will be provided in short introductions to chapters grouped by time periods and themes. The foreword by Mary Beaudry and the afterword by LuAnne DeCunzo bookend the individual case studies and add theoretical weight to the volume. Historical Archaeology of New York City focuses on specific individual life stories, or stories of groups of people, as a way to present archaeological theory and research. Archaeologists work with material culture¿artifacts¿to recreate daily lives and study how culture works; this book is an example of how to do this in a way that can attract people interested in history as well as in anthropological theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

  • Michael J. Rathbone

    Editore: Springer US, Springer New York Mär 2015, 2015

    ISBN 10: 1489975578 ISBN 13: 9781489975577

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This volume provides a comprehensive overview of the current issues facing scientists working on delivering drugs locally and systemically via the membranes that line the mouth. The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems. It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods.In 11 authoritative chapters, the book affords an in-depth evaluation of the major issues associated with this route of administration, namely the retention of the drug/product at the site of administration and increasing drug permeability through the oral mucosa. The book provides insights into the in vitro and in vivo methods available to assess drug permeability and retention, offers solutions on how to improve the permeation of the drugs through the oral mucosa, and explores approaches to prolong drug/product retention at the site of administration. It also indicates future directions in research and product development. Oral Mucosal Drug Delivery and Therapy is a key resource for those wishing to extend their knowledge of this field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.

  • Nurcan Yalman

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493926535 ISBN 13: 9781493926534

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -Contesting Ethnoarchaeologiesprovides a systematic overview of major non-American traditions of ethnoarchaeology, with a particular focus on Europe and Asia. It explores all stages of their research agenda. These ethnoarchaeologies were embedded in theoretical traditions of local archaeologies. Moreover, ethnoarchaeological studies carried out in these different settings targeted a wide range of different issues and addressed numerous questions of covering all sorts of different issues. Consequently, achieved results and data have been largely idiosyncratic and hardly compatible. Hence, this volume aims not only to conceptualize characteristics of these diverse ethnoarchaeologies but more importantly put them in a broader context of the development of archaeology in different parts ofEurope and Asia.The contributors to the volume express their own diverse views on the cognitive and interpretative value of ethnoarchaeology for studying prehistoric past, based on particular cases of experience and research. As such, the volume is not only a valuable overview of numerous ethnoarchaeological practices in different parts of the region, but also a significant contribution to the history of archaeological thought. This perspective shall make the book of wider applicability and make possible to put up ethnoarchaeology as an immanent and important element of archaeological theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.

  • Ashish Tewari

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1493923676 ISBN 13: 9781493923670

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This monograph presents the state of the art in aeroservoelastic (ASE) modeling and analysis and develops a systematic theoretical and computational framework for use by researchers and practicing engineers. It is the first book to focus on the mathematical modeling of structural dynamics, unsteady aerodynamics, and control systems to evolve a generic procedure to be applied for ASE synthesis. Existing robust, nonlinear, and adaptive control methodology is applied and extended to some interesting ASE problems, such as transonic flutter and buffet, post-stall buffet and maneuvers, and flapping flexible wing.The author derives a general aeroservoelastic plant via the finite-element structural dynamic model, unsteady aerodynamic models for various regimes in the frequency domain, and the associated state-space model by rational function approximations. For more advanced models, the full-potential, Euler, and Navier-Stokes methods for treating transonic and separated flows are also briefly addressed. Essential ASE controller design and analysis techniques are introduced to the reader, and an introduction to robust control-law design methods of LQG/LTR and H2/H¿ synthesis is followed by a brief coverage of nonlinear control techniques of describing functions and Lyapunov functions. Practical and realistic aeroservoelastic application examples derived from actual experiments are included throughout.Aeroservoelasiticity fills an important gap in the aerospace engineering literature and will be a valuable guide for graduate students and advanced researchers in aerospace engineering, as well as professional engineers, technicians, and test pilots in the aircraft industry and laboratories.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.

  • Dmitry Panchenko

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489993738 ISBN 13: 9781489993731

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -The celebrated Parisi solution of the Sherrington-Kirkpatrick model for spin glasses is one of the most important achievements in the field of disordered systems. Over the last three decades, through the efforts of theoretical physicists and mathematicians, the essential aspects of the Parisi solution were clarified and proved mathematically. The core ideas of the theory that emerged are the subject of this book, including the recent solution of the Parisi ultrametricity conjecture and a conceptually simple proof of the Parisi formula for the free energy. The treatment is self-contained and should be accessible to graduate students with a background in probability theory, with no prior knowledge of spin glasses. The methods involved in the analysis of the Sherrington-Kirkpatrick model also serve as a good illustration of such classical topics in probability as the Gaussian interpolation and concentration of measure, Poisson processes, and representation results for exchangeable arrays.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 168 pp. Englisch.

  • L A Stefanski

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489987932 ISBN 13: 9781489987938

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -¿This book is for students and researchers who have had a first year graduate level mathematicalstatistics course. It covers classical likelihood, Bayesian, and permutation inference;an introduction to basic asymptotic distribution theory; and modern topics like M-estimation,the jackknife, and the bootstrap. R code is woven throughout the text, and there are a large numberof examples and problems.An important goal has been to make the topics accessible to a wide audience, with little overt relianceon measure theory. A typical semester course consists of Chapters 1-6 (likelihood-based estimationand testing, Bayesian inference, basic asymptotic results) plus selections from M-estimation and related testing and resampling methodology.Dennis Boos and Len Stefanski are professors in the Department of Statistics at North Carolina State.Their research has been eclectic, often with a robustness angle, although Stefanski is also known forresearch concentrated on measurement error, including a co-authored book on non-linear measurementerror models. In recent years the authors have jointly worked on variable selection methods.¿Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 588 pp. Englisch.


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  • Joe Zhu

    Editore: Springer US, Springer New York Mär 2015, 2015

    ISBN 10: 1489975527 ISBN 13: 9781489975522

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This handbook represents a milestone in the progression of Data Envelopment Analysis (DEA). Written by experts who are often major contributors to DEA theory, it includes a collection of chapters that represent the current state-of-the-art in DEA research. Topics include distance functions and their value duals, cross-efficiency measures in DEA, integer DEA, weight restrictions and production trade-offs, facet analysis in DEA, scale elasticity, benchmarking and context-dependent DEA, fuzzy DEA, non-homogenous units, partial input-output relations, super efficiency, treatment of undesirable measures, translation invariance, stochastic nonparametric envelopment of data, and global frontier index.Focusing only on new models/approaches of DEA, the book includes contributions from Juan Aparicio, Mette Asmild, Yao Chen, Wade D. Cook, Juan Du, Rolf Färe, Julie Harrison, Raha Imanirad, Andrew Johnson, Chiang Kao, Abolfazl Keshvari, Timo Kuosmanen, Sungmook Lim, Wenbin Liu, Dimitri Margaritis, Reza Kazemi Matin, Ole B. Olesen, Jesus T. Pastor, Niels Chr. Petersen, Victor V. Podinovski, Paul Rouse, Antti Saastamoinen, Biresh K. Sahoo, Kaoru Tone, and Zhongbao Zhou.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 480 pp. Englisch.

  • Joseph J Degeorge

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489994076 ISBN 13: 9781489994073

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -Thisvolume will consider one of ICH¿s major categories, Safety i.e. topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but even after ICH6 no explanations have been given during a formal Congress about the background of the ICH Guidance documents. Even more important than what has been written, might have been those thoughts of the experts that are not included in the Guidance documents. Why has the guideline been written as it is written, and why have some aspects been deleted. These and other related questions are the contents of this book, written by experts who were involved in the ICH process. Furthermore, the chapters will contain discussions on the ¿lessons learnt¿ and ¿future developments¿.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 328 pp. Englisch.

  • Linda O. Narhi

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489992464 ISBN 13: 9781489992468

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 304 pp. Englisch.

  • Barry S. Cooper

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489990496 ISBN 13: 9781489990495

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -Contingent on funding being available, a Festschrift will be held in honor of Dr. John Yuille¿s career as a Forensic Psychologist. He has become one of the most visible and respected Canadian psychologists worldwide. In light of his upcoming retirement in December 2006, the Festschrift will recognize Dr. Yuille¿s achievements in the areas of eyewitness memory research (i.e., pioneering a new research paradigm that grants better validity), investigative interviewing (i.e., the development and use of the Step Wise Interview Protocol), and credibility assessment (i.e., introducing Statement Validity Analysis to North America). New directions for future work will be explored at the workshop. The focus of this Festschrift will be three-fold:1. International. Dr. Yuille¿s work has influenced law enforcement practices and stimulated research in and outside of Canada. The international and multicultural aspects of the work that Dr. Yuille has inspired will be reflected and promoted by this workshop.2. Interdisciplinary. Dr. Yuille is internationally known as an expert, consultant and trainer to law enforcement. As such, Dr. Yuille¿s work has also influenced other disciplines, e.g., the law, social work, oral history. The participants of this Festschrift will gain insight into other professionals¿ perspectives and foster potential collaborations on future projects.3. Emphasis on applied research. A hallmark of Dr. Yuille¿s research has been the application of field and archival methods, which made his work directly applicable to forensically relevant contexts. The potential future directions of applied forensic research will be discussed at this Festschrift.The importance of the subject at this time: A lack of integrative models in the literatures of eyewitness memory and the assessment of truthfulness and deception. Presenters of the Festschrift have recently developed such models and will discuss them at theFestschrift. Publishing these models and their discussions will spark further research to validate or modify them. New, pioneering field research based on such integrative models has recently been conducted. This book would be one of the first publications of the results.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 372 pp. Englisch.

  • Maria Jose Alcaraz

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489988823 ISBN 13: 9781489988829

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -This next volume in our established series proposes to systematically review the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as ¿oxidative stress¿, in the pathology of arthritis and other joint diseases. It will describe the most current diagnostic tools , laboratory methods and technology, to suggest ways of prevention and treatment and to emphasize the concept of the bench-to-bedside approach. The book will also provide specific coverage on emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents and several more relevant aspects. In addition, the book will promote the concept of using biomarkers representative of oxidative stress reactions and free radical damage , as well as describe the effect of antioxidants in treating disease in clinical trials. The content will be valuable to researchers studying the development of arthritis/joint disease, and clinicians treating patients with these diagnoses.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 428 pp. Englisch.

  • Irena Peeva

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489999078 ISBN 13: 9781489999078

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -This contributed volume brings together the highest quality expository papers written by leaders and talented junior mathematicians in the field of Commutative Algebra. Contributions cover a very wide range of topics, including core areas in Commutative Algebra and also relations to Algebraic Geometry, Algebraic Combinatorics, Hyperplane Arrangements, Homological Algebra, and String Theory. The book aims to showcase the area, especially for the benefit of junior mathematicians and researchers who are new to the field; it will aid them in broadening their background and to gain a deeper understanding of the current research in this area. Exciting developments are surveyed and many open problems are discussed with the aspiration to inspire the readers and foster further research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 716 pp. Englisch.


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  • Nikos Paragios

    Editore: Springer US, Springer New York Mär 2015, 2015

    ISBN 10: 0387097481 ISBN 13: 9780387097480

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Buch. Condizione: Neu. Neuware -This book explains the process of computer assisted biomedical image analysis diagnosis through mathematical modeling and inference of image-based bio-markers. It covers five crucial thematic areas: methodologies, statistical and physiological models, biomedical perception, clinical biomarkers, and emerging modalities and domains.The dominant state-of-the-art methodologies for content extraction and interpretation of medical images include fuzzy methods, level set methods, kernel methods, and geometric deformable models. The models and techniques discussed are used in the diagnosis, planning, control and follow-up of medical procedures. Throughout the book, challenges and limitations are explored along with new research directions.Handbook of Biomedical Imaging offers a unique guide to the entire chain of biomedical imaging, explaining how image formation is done and how the most appropriate techniques are used to address demands and diagnoses. Radiologists, research scientists, senior undergraduate and graduate students in health sciences and engineering, and university professors will find this to be an exceptional reference.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 520 pp. Englisch.


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  • Brian T. Denton

    Editore: Springer US, Springer New York Mär 2015, 2015

    ISBN 10: 1489995501 ISBN 13: 9781489995506

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. Neuware -From the Preface:Collectively, the chapters in this book address application domains including inpatient and outpatient services, public health networks, supply chain management, and resource constrained settings in developing countries. Many of the chapters provide specific examples or case studies illustrating the applications of operations research methods across the globe, including Africa, Australia, Belgium, Canada, the United Kingdom, and the United States.Chapters 1-4 review operations research methods that are most commonly applied to health care operations management including: queuing, simulation, and mathematical programming. Chapters 5-7 address challenges related to inpatient services in hospitals such as surgery, intensive care units, and hospital wards. Chapters 8-10 cover outpatient services, the fastest growing part of many health systems, and describe operations research models for primary and specialty care services, and how to plan for patient no-shows. Chapters 12 ¿ 16 cover topics related to the broader integration of health services in the context of public health, including optimizing the location of emergency vehicles, planning for mass vaccination events, and the coordination among different parts of a health system. Chapters 17-18 address supply chain management within hospitals, with a focus on pharmaceutical supply management, and the challenges of managing inventory for nursing units. Finally, Chapters 19-20 provide examples of important and emerging research in the realm of humanitarian logistics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 548 pp. Englisch.

  • Tomasz Burzykowski

    Editore: Springer New York, Springer US Mär 2015, 2015

    ISBN 10: 1489996672 ISBN 13: 9781489996671

    Lingua: Inglese

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania

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    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Linear mixed-effects models (LMMs) are an important class of statistical models that can be used to analyze correlated data. Such data are encountered in a variety of fields including biostatistics, public health, psychometrics, educational measurement, and sociology. This book aims to support a wide range of uses for the models by applied researchers in those and other fields by providing state-of-the-art descriptions of the implementation of LMMs in R. To help readers to get familiar with the features of the models and the details of carrying them out in R, the book includes a review of the most important theoretical concepts of the models. The presentation connects theory, software and applications. It is built up incrementally, starting with a summary of the concepts underlying simpler classes of linear models like the classical regression model, and carrying them forward to LMMs. A similar step-by-step approach is used to describe the R tools for LMMs. All the classes of linearmodels presented in the book are illustrated using real-life data. The book also introduces several novel R tools for LMMs, including new class of variance-covariance structure for random-effects, methods for influence diagnostics and for power calculations. They are included into an R package that should assist the readers in applying these and other methods presented in this text.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 576 pp. Englisch.