springer us apr 1984 (3 risultati)

Buch. Condizione: Neu. Neuware - Research on antiviral drugs and their mode of action in infected cells. in animals and in man. has led to a better understanding of the molecular pro cesses involved in virus replication. Screeninq of large numbers of natural and semisynthetic compounds resulted in the characterization of certain sub stances that had a limited efficiency as antiviral druqs. A few chemically synthesized compounds were also found to be effective as antiviral agents in the chemotherapy of human virus diseases. A major difficulty in the develop ment of effective antiviral agents has been the lack of selectivity. and toxicity for uninfected cells. of drugs that effectively inhibited virus replication in vitro. Further understanding of the molecular processes of virus replication in infected cells has resulted in the development of new antivirals directed at virus-coded enzymes or proteins. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs. The present book deals with a number of antiviral drugs effective against herpes simplex viruses and provides some insight into the molecular aspects of virus replication. It also throws light on the new approaches to the development of antiviral drugs. The molecular basis of the antiviral activity of new and known drugs and their possible use in chemotherapy of viral disease are presented in this book.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our earlier book, How We Know: An Exploration of the Scientific Process, was written to give some conception of what the scientific approach is like, how to recognize it, how to distinguish it from other approaches to understanding the world, and to give some feeling for the intellectual excitement and aesthetic satisfactions of science. These goals represented our concept of the term 'scientific literacy.' Though the book was written for the general reader, to our surprise and gratification it was also used as a text in about forty colleges, and some high schools, for courses in science for the non-scientist, in methodology of science for social and behavioral sciences, and in the philosophy of science. As a result we were encouraged to write a textbook with essentially the same purpose and basic approach, but at a level appropriate to college students. We have drawn up problems for those chapters that would benefit from them, described laboratory experiments that illustrate important points discussed in the text, and made suggestions for additional readings, term papers, and other projects. Throughout the book we have introduced a number of chapters and appendices that provide examples of the uses of quantitative thinking in the sciences: logic, math ematics, probability, statistics, and graphical representation. 428 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Our earlier book, How We Know: An Exploration of the Scientific Process, was written to give some conception of what the scientific approach is like, how to recognize it, how to distinguish it from other approaches to understanding the world, and to give some feeling for the intellectual excitement and aesthetic satisfactions of science. These goals represented our concept of the term 'scientific literacy.' Though the book was written for the general reader, to our surprise and gratification it was also used as a text in about forty colleges, and some high schools, for courses in science for the non-scientist, in methodology of science for social and behavioral sciences, and in the philosophy of science. As a result we were encouraged to write a textbook with essentially the same purpose and basic approach, but at a level appropriate to college students. We have drawn up problems for those chapters that would benefit from them, described laboratory experiments that illustrate important points discussed in the text, and made suggestions for additional readings, term papers, and other projects. Throughout the book we have introduced a number of chapters and appendices that provide examples of the uses of quantitative thinking in the sciences: logic, math ematics, probability, statistics, and graphical representation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 428 pp. Englisch.