springer us feb 1987 (15 risultati)

Buch. Condizione: Neu. Neuware - This book is derived from a Symposium held at the 190th National American Chemical Society Meeting, which was held in the Fall of 1985, in Chicago, and was sponsored by the Division of Polymeric Materials: Science & Engineering. This Symposium was, in turn, a follow-up on an earlier one held in Houston, TX, in the Spring of 1980, which was pub lished as the book Biomedical and Dental Applications of Polymers [Plenum Press, New York, 1981]. In that earlier book, our opening Preface passage quoted King David, 1 will praise Thee; for I am fearfully and made . -- - (Psalm 139:14). As we noted five years ago, sickness wonderfully of many types does occur in our wonderfully made bodies, but much human suffering can be aided by biomedical polymers. That earlier book con sidered much of the fantastic progress that had been made in biomedical polymers during the previous quarter century and brought many of these topics up to date. That Symposium, and book, noted that much help was available for the varied afflictions and problems that sometimes beset, and upset, our God-given bodies, and the promise of new and important advances was held out as a shining ray of hope amidst the gloom of sickness and affliction. The present volume is an update on the advances that have occurred since the 1981 book and sets the stage for even greater advances in the future.

Buch. Condizione: Neu. Neuware - It is indeed ironical that in the absence of a complete knowledge of Pathophysiology, clinical cardiologists are left with no choice but to do the best they can to help the patient with the armamentarium of drugs at their disposal. But nothing could be further from truth than to treat the diagnosed end point of a disease process without a full understanding of its patho physiology. This point was eloquently made by Dr. Arnold Katz in his Presidential Address (Chapter 1) at the 8th Annual Meeting of the American Section of the International Society for Heart Research held in Winnipeg, Canada, July 8-11, 1986. This volume represents a part of the scientific proceedings of this Meeting. From a reading of this treatise it will become evident that discoveries of newer scientific facts as well as a better understanding of pathophysiology are continuously influencing/ improving our therapeutic approaches in modern medicine. In this book, latest biochemical, physiological and pharmacological findings on different experimental models such as Myocaridal hypertrophy, Hypertension and heart failure, Diabetes, Cardio myopathies and Cardiac function in shock are described by internationally recognised experts. Hopefully information presented here will provide another building block to the edifice of Science of Cardiology which we all are trying to create. Acknowledgements We are grateful to the following Agencies and Foundations for their generous financial support of the Symposium, which formed the basis of this book. A. Major Contributors: 1. Manitoba Heart Foundation 2. Sterling-Winthrop Research Institute 3. Squibb Canada, Inc.

Buch. Condizione: Neu. Neuware - The importance of heart and artery disease as a cause of death and disability is difficult to exaggerate: it causes over half of all deaths in the western world and now accounts for one-quarter of deaths in the entire world. This appalling incidence persists in spite of commendable progress in treatment and prevention, particularly in the last two or three decades. Deaths from coronary disease have decreased by a third in the past twenty years and stroke has decreased by a half in the same period. This remarkable improvement, saving thousands of lives per year, has come about due to changes in life style (low fat diet, control of high blood pressure, less smoking and more exercise) and progress in treatment (more effective drugs, coronary care units, pacemakers, and cardiac surgery). Progress in understanding the pathophysiologic and pharn,acologic mechanisms operative in heart disease have been paramount in the development of more rational and more effective therapy. Dramatic and spectacular surgical treatments have fired the public imagination. Bypass surgery is commonplace and results in complete or considerable relief of symptoms in the majority of patients operated upon.

Buch. Condizione: Neu. Neuware - In the course of the last two decades, it has become increasingly evident that the sarcolemmal, sarcoplasmic reticular and mitochondrial membrane systems play an important role in determining the status of heart funotion in health and disease. These organelles have been shown to be intimately involved in the regulation of cation movements during the contraotion-relaxation cycle. Various proteins imbedded in the phospholipid 2+ + - + + bilayers of these membranes control Ca ,Na, Cl ,K and H concentrations within the oytoplasm by indirect or direct means. Cationic channels, Na+, + 2+ 2+ 2+ + 2+ + + K -ATPase, Ca IMg ATPase, Ca pump, Na -Ca exchanger, Na -II exchanger and adenylate cyclase affect myocardial funotion and viability through their role as regulators of specific ion movements. However, proteins are not the only important constituents of the membrane. Any disturbance in the interaction between proteins and phospholipids in the membrane has been suggested to alter the funotion of the organelles, upset ionic homeostasis and precipitate the development of abnormalities in oardiac performance. It is, therefore, orucial to understand the faotors whioh regulate membrane funotion in their totality if we are to oomprehend the nature of heart performanoe in healthy subjects. Similarly, the study of membrane dysfunotion in a wide variety of experimental models of heart disease at various stages of failure is essential if we are to fully understand the pathogenesis of heart dysfunotion and improve its treatment.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I am indebted to my thesis advisor, Michael Genesereth, for his guidance, inspiration, and support which has made this research possible. As a teacher and a sounding board for new ideas, Mike was extremely helpful in pointing out Haws, and suggesting new directions to explore. I would also like to thank Harold Brown for introducing me to the application of artificial intelligence to reasoning about designs, and his many valuable comments as a reader of this thesis. Significant contribu tions by the other members of my reading committee, Mark Horowitz, and Allen Peterson have greatly improved the content and organization of this thesis by forcing me to communicate my ideas more clearly. I am extremely grateful to the other members of the Logic Group at the Heuristic Programming Project for being a sounding board for my ideas, and providing useful comments. In particular, I would like to thank Matt Ginsberg, Vineet Singh, Devika Subramanian, Richard Trietel, Dave Smith, Jock Mackinlay, and Glenn Kramer for their pointed criticisms. This research was supported by Schlumberger Palo Alto Research (previously Fairchild Laboratory for Artificial Intelligence). I am grateful to Peter Hart, the former head of the AI lab, and his successor Marty Tenenbaum for providing an excellent environment for performing this research. 212 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume addresses key issues in the sociology of education concerning how schools are organized for instruction and what processes link school organization and instruction to educa tional achievement. The content of the chapters represents a shift in focus from traditional and even recent themes in soci ology of education, including the study of school effects and of classroom processes, to a concern with the social organization of schools and its consequences for student outcomes. Rather than reviewing or evaluating existing research, the chapters present new and developing conceptualizations of the school ing process and provide theoretical models to guide future empirical work on schools. A unique feature of this book is its heavy emphasis on theory. Each chapter presents a theoretical model or argument concerning an issue of central importance in sociology of edu cation. The empirical analyses and simulations that are included are often more for illustrative purposes than for rigorous hypothesis testing, and some chapters have no data analysis at all. The major strength of the volume, therefore, lies in the new conceptualizations and reconceptualizations it provides of fundamental processes relating school organization to student learning. Theoretical work such as this is exactly what is needed in an area that has traditionally been, for the most part, empir ical and atheoretical. Another important feature of this volume is the various approaches it presents to the study of school organization. 252 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Linear algebra and matrix theory are essentially synonymous terms for an area of mathematics that has become one of the most useful and pervasive tools in a wide range of disciplines. It is also a subject of great mathematical beauty. In consequence of both of these facts, linear algebra has increasingly been brought into lower levels of the curriculum, either in conjunction with the calculus or separate from it but at the same level. A large and still growing number of textbooks has been written to satisfy this need, aimed at students at the junior, sophomore, or even freshman levels. Thus, most students now obtaining a bachelor's degree in the sciences or engineering have had some exposure to linear algebra. But rarely, even when solid courses are taken at the junior or senior levels, do these students have an adequate working knowledge of the subject to be useful in graduate work or in research and development activities in government and industry. In particular, most elementary courses stop at the point of canonical forms, so that while the student may have 'seen' the Jordan and other canonical forms, there is usually little appreciation of their usefulness. And there is almost never time in the elementary courses to deal with more specialized topics like nonnegative matrices, inertia theorems, and so on. In consequence, many graduate courses in mathematics, applied mathe matics, or applications develop certain parts of matrix theory as needed. 280 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume addresses key issues in the sociology of education concerning how schools are organized for instruction and what processes link school organization and instruction to educa tional achievement. The content of the chapters represents a shift in focus from traditional and even recent themes in soci ology of education, including the study of school effects and of classroom processes, to a concern with the social organization of schools and its consequences for student outcomes. Rather than reviewing or evaluating existing research, the chapters present new and developing conceptualizations of the school ing process and provide theoretical models to guide future empirical work on schools. A unique feature of this book is its heavy emphasis on theory. Each chapter presents a theoretical model or argument concerning an issue of central importance in sociology of edu cation. The empirical analyses and simulations that are included are often more for illustrative purposes than for rigorous hypothesis testing, and some chapters have no data analysis at all. The major strength of the volume, therefore, lies in the new conceptualizations and reconceptualizations it provides of fundamental processes relating school organization to student learning. Theoretical work such as this is exactly what is needed in an area that has traditionally been, for the most part, empir ical and atheoretical. Another important feature of this volume is the various approaches it presents to the study of school organization.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Technology Assessment and Nova Scotian Tidal Power Projects.- Scientific Issues in the Assessment of the Transboundary Effects of Fundy Tidal Power.- Legal Decisionmaking Frameworks for Fundy Tidal Power.- Effectiveness of Canadian and U.S. Environmental Assessment Processes in Evaluating Transboundary Impacts.- Seeking Legal Redress for Transboundary Environmental Injury.- Decisionmaking Improvements and Alternatives.- Summary of Conclusions and Recommendations.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Endocrinology, as a discipline, was a late arrival in the corpus of established subjects. Its growth in recent years has been prodigious, extending from mor phology to molecular levels. Most of the major endocrine glands were noted by the early anatomists, although the adrenal glands were not described until 1563 by Bartholomaeus Eustachius (1520-1574). On the other hand, elucidation of the function of these glands was extremely slow. Key work by A. A. Berthold (1849), although overlooked at the time, showed that comb atrophy in castrated fowl was prevented by testis transplantation. The idea that glands produced substances reach ing the bloodstream directly and not via excretory ducts stemmed from Claude Bernard, who first used the term internal secretion in 1855. The clinical observa tions of Thomas Addison at Guy's Hospital-published as a monograph in 1855 entitled The Constitutional and Local Effects of Disease of the Suprarenal Capsules -were seminal. However, the stimulus of this early research did not bring imme diate widespread further investigations. Upon the discovery of secretin in 1902, Bayliss and Starling considered the term 'internal secretion' to be clumsy, and the term 'hormone' was coined (from OQ[!UW-1 excite or arouse) and it was first used by Starling in his Croonian of 1905. 686 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From the President of the Research Society on Alcoholism In recent years, increasingly convincing evidence in support of a biobehavioral conceptual model of the etiology of alcoholism has emerged. In this model, the disorder is perceived as arising from the interaction of geneticlbiological vulnerability and psychosocial risk. Drinking, or alcohol-seeking, is a metric trait. Alcoholism, which is a state of abnormally intense alcohol-seeking be havior that, over time, leads to the alcohol dependence syndrome, lies at the extreme, high end of this quantitative measure. Metric traits are influenced by multiple genes; the extent of genetic loading of biological risk for alcoholism would be different in different individuals. Added to this kind of variability is the wide range of options for exposure to the psychosocial risk factors of heavy drinking provided by modern society. Further, environmental prov ocation also changes when life events change. It is not surprising, therefore, from the combination of the kinds of genetic and environmental variability described above that there is a wide array of patterns of expression of the disorder alcoholism, referred to by some as 'alcoholisms. ' In the search for understanding of underlying mechanisms and rational bases for potential therapy, it is important to focus our attention on the final common pathway of this disorder, alcohol-seeking behavior. This series, ever since its beginning in 1983, has been sensitive to the complexities of the interaction between biological and psychosocial risk factors in alcoholism. 492 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Endocrinology, as a discipline, was a late arrival in the corpus of established subjects. Its growth in recent years has been prodigious, extending from mor phology to molecular levels. Most of the major endocrine glands were noted by the early anatomists, although the adrenal glands were not described until 1563 by Bartholomaeus Eustachius (1520-1574). On the other hand, elucidation of the function of these glands was extremely slow. Key work by A. A. Berthold (1849), although overlooked at the time, showed that comb atrophy in castrated fowl was prevented by testis transplantation. The idea that glands produced substances reach ing the bloodstream directly and not via excretory ducts stemmed from Claude Bernard, who first used the term internal secretion in 1855. The clinical observa tions of Thomas Addison at Guy's Hospital-published as a monograph in 1855 entitled The Constitutional and Local Effects of Disease of the Suprarenal Capsules -were seminal. However, the stimulus of this early research did not bring imme diate widespread further investigations. Upon the discovery of secretin in 1902, Bayliss and Starling considered the term 'internal secretion' to be clumsy, and the term 'hormone' was coined (from OQ[!UW-1 excite or arouse) and it was first used by Starling in his Croonian of 1905.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 686 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -From the President of the Research Society on Alcoholism In recent years, increasingly convincing evidence in support of a biobehavioral conceptual model of the etiology of alcoholism has emerged. In this model, the disorder is perceived as arising from the interaction of geneticlbiological vulnerability and psychosocial risk. Drinking, or alcohol-seeking, is a metric trait. Alcoholism, which is a state of abnormally intense alcohol-seeking be havior that, over time, leads to the alcohol dependence syndrome, lies at the extreme, high end of this quantitative measure. Metric traits are influenced by multiple genes; the extent of genetic loading of biological risk for alcoholism would be different in different individuals. Added to this kind of variability is the wide range of options for exposure to the psychosocial risk factors of heavy drinking provided by modern society. Further, environmental prov ocation also changes when life events change. It is not surprising, therefore, from the combination of the kinds of genetic and environmental variability described above that there is a wide array of patterns of expression of the disorder alcoholism, referred to by some as 'alcoholisms. ' In the search for understanding of underlying mechanisms and rational bases for potential therapy, it is important to focus our attention on the final common pathway of this disorder, alcohol-seeking behavior. This series, ever since its beginning in 1983, has been sensitive to the complexities of the interaction between biological and psychosocial risk factors in alcoholism.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 492 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The current volume covers electron transfer reactions, substitution and relation reactions, and reactions of organometallic compounds.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 560 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The current volume covers electron transfer reactions, substitution and relation reactions, and reactions of organometallic compounds. 560 pp. Englisch.