springer us feb 2012 (369 risultati)

Taschenbuch. Condizione: Neu. Neuware -This book is for the most part made up of the invited papers presented at the International Conference on Applica tions of the Kdssbauer effect, held at Aye1eth Hashahar, Israel, in August 1972. The purpose of the conference was to review perspec tives in MHssbauer spectroscopy from the point of view of applications in various fields of science - mainly physics, chemistry, and biology. It was hoped that the bringing together of scientists who work in different disciplines but use a common tool would encourage interdisciplinary re search and widen the horizon of the individual researcher. Both these features have been an important and unique characteristic of Kdssbauer research in the past decade. Accordingly, the main papers were presented in the following areas: magnetic properties of solids, applications to in organic chemistry, biochemical studies, amorphous systems, metal alloys, advances in high-resolution studies, and the new techniques for studying recoil-free spectra from isolated atoms in inert materials. A special panel discussion was devoted to the subject of phase transitions. Recent years have witnessed a rapid growth in the use of X-ray photoelec tron spectroscopy for the study of the physics and chemistry of solids. A report on this area of research and its rela tion to Kdssbauer studies has been included.

Taschenbuch. Condizione: Neu. Neuware - This book is for the most part made up of the invited papers presented at the International Conference on Applica tions of the Kdssbauer effect, held at Aye1eth Hashahar, Israel, in August 1972. The purpose of the conference was to review perspec tives in MHssbauer spectroscopy from the point of view of applications in various fields of science - mainly physics, chemistry, and biology. It was hoped that the bringing together of scientists who work in different disciplines but use a common tool would encourage interdisciplinary re search and widen the horizon of the individual researcher. Both these features have been an important and unique characteristic of Kdssbauer research in the past decade. Accordingly, the main papers were presented in the following areas: magnetic properties of solids, applications to in organic chemistry, biochemical studies, amorphous systems, metal alloys, advances in high-resolution studies, and the new techniques for studying recoil-free spectra from isolated atoms in inert materials. A special panel discussion was devoted to the subject of phase transitions. Recent years have witnessed a rapid growth in the use of X-ray photoelec tron spectroscopy for the study of the physics and chemistry of solids. A report on this area of research and its rela tion to Kdssbauer studies has been included.

Taschenbuch. Condizione: Neu. Neuware - 1 Clinical and Molecular Genetics of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency.- Introduction: Adrenal Steroidogenesis.- The Physiology of 21-Hydroxylase Deficiency.- Genetics of the 21-Hydroxylase Locus.- Southern Blotting Studies in CAH.- Gene Defects Detectable by Southern Blotting.- Point Mutations in CAH.- Prenatal Diagnosis of CAH.- References.- 2 Genetic Aspects of Amyloidosis.- Amyloidosis: Historical Background.- Amyloidosis: Definition.- Chemical Classification of the Amyloid Syndromes.- Transthyretin-Associated Amyloidosis.- Familial Mediterranean Fever and Other Hereditary Amyloidoses of the Amyloid A (AA) Type.- ACYS (Cystatin C) Hereditary Cerebral Hemorrhage with Amyloidosis: (HCHWA)-Iceland.- Aß Amyloidosis: Dutch-Type HCHWA, Alzheimer's Disease, and Down Syndrome.- AGEL: Familial Amyloidosis of the Finnish Type.- AAPOAI: Familial Amyloid Polyneuropathy, Iowa-(Van Allen).- AC AL: Multiple Endocrine Neoplasia.- Miscellaneous Hereditary Amyloidoses.- The Treatment of Hereditary Forms of Amyloidosis.- Conclusions.- References.- 3 Huntington's Disease.- Clinical Characteristics of HD.- Neuropathology and Neurochemistry.- Epidemiology.- A Molecular Genetic Approach to Investigation of HD.- Success of the Linkage Strategy.- Defining the HD Candidate Region.- Isolation of DNA Probes from the Candidate Region.- Fine Structure Physical Mapping of the Candidate Region.- Genetic Mapping of the Candidate Region.- Positioning of the HD Gene by Apparent Crossover Events.- Linkage Disequilibrium.- What Is the HD Gene .- References.- 4 Biochemical and Molecular Genetics of Cystic Fibrosis.- Early Attempts to Identify Biochemical Markers for CF.- Epithelial Ion Transport.- CF Gene Mapping.- Identification of the CF Gene.- The CF Gene Product(CFTR).- Genotype and Phenotype.- Explanations for High CF Gene Frequency.- Genetic Diagnosis.- Concluding Remarks.- References.- 5 Molecular Genetics of von Recklinghausen Neurofibromatosis.- Clinical Features.- Genetics of NF1.- Biochemical and Neurobiological Aspects.- Molecular Genetics.- Future Directions.- References.- Addenda.

Taschenbuch. Condizione: Neu. Neuware - This volume presents the proceedings of the Second International Sym posium on Acoustical Holography, which was held at the Douglas Advanced Research Laboratories on 6 and 7 March 1969, fifteen months after the first symposium. Space was limited to about 110 seats, with representatives from nine countries attending. These countries included Canada, England, France, Japan, Mexico, Scotland, Sweden, Switzerland, and the United States. The symposium consisted of 21 formal papers. The twenty second, by Dr. U. Fehr, was not read, but is included in these proceedings. The manu script of the interesting paper on acoustic propagation in a turbulent medium which was read by Dr. O. K. Mawardi was not received in time for publication in these proceedings, and we look forward to its publication perhaps at a later date in the open literature. In addition to the formal papers there were three informal presentations at the end of the meeting which were given by Dr. A. Lohmann, by L. A. Cram and K. O. Rossiter, and by T. S. Graham, which are also included in these proceedings. At the end of the formal presentations Dr. Lewis Larmore summarized the symposium and discussed some of the highlights. For the symposium summary and a summary of these proceedings the reader is referred to Chapter 1.

Taschenbuch. Condizione: Neu. Neuware -This book is for the most part made up of the invited papers presented at the International Conference on Applica tions of the Kdssbauer effect, held at Aye1eth Hashahar, Israel, in August 1972. The purpose of the conference was to review perspec tives in MHssbauer spectroscopy from the point of view of applications in various fields of science - mainly physics, chemistry, and biology. It was hoped that the bringing together of scientists who work in different disciplines but use a common tool would encourage interdisciplinary re search and widen the horizon of the individual researcher. Both these features have been an important and unique characteristic of Kdssbauer research in the past decade. Accordingly, the main papers were presented in the following areas: magnetic properties of solids, applications to in organic chemistry, biochemical studies, amorphous systems, metal alloys, advances in high-resolution studies, and the new techniques for studying recoil-free spectra from isolated atoms in inert materials. A special panel discussion was devoted to the subject of phase transitions. Recent years have witnessed a rapid growth in the use of X-ray photoelec tron spectroscopy for the study of the physics and chemistry of solids. A report on this area of research and its rela tion to Kdssbauer studies has been included. 268 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware - Computer vision is one of the most complex and computationally intensive problem. Like any other computationally intensive problems, parallel pro cessing has been suggested as an approach to solving the problems in com puter vision. Computer vision employs algorithms from a wide range of areas such as image and signal processing, advanced mathematics, graph theory, databases and artificial intelligence. Hence, not only are the comput ing requirements for solving vision problems tremendous but they also demand computers that are efficient to solve problems exhibiting vastly dif ferent characteristics. With recent advances in VLSI design technology, Single Instruction Multiple Data (SIMD) massively parallel computers have been proposed and built. However, such architectures have been shown to be useful for solving a very limited subset of the problems in vision. Specifically, algorithms from low level vision that involve computations closely mimicking the architec ture and require simple control and computations are suitable for massively parallel SIMD computers. An Integrated Vision System (IVS) involves com putations from low to high level vision to be executed in a systematic fashion and repeatedly. The interaction between computations and information dependent nature of the computations suggests that architectural require ments for computer vision systems can not be satisfied by massively parallel SIMD computers.

Taschenbuch. Condizione: Neu. Neuware - Few advances in cardiovascular medicine have so captured the inter est of physicians and the public alike as has coronary artery bypass surgery. Cardiologists who lived through the era of false hopes and frustrations of previous' operations' for coronary artery disease can fully appreciate what this major advance offers to their patients. The number of papers on this topic presented at national meetings attest to its popularity, but also make it increasingly difficult for anyone to assimilate all the data. Practitioners who must consider coronary artery bypass surgery for their patients may thus have difficulty in coming to some rational decision regarding the indications for the operation and its consequences. Depending on the 'authority' that one reads, there is still some controversy as to which patients are candidates for coronary artery surgery. This monograph on the prac tice of coronary artery bypass surgery, therefore, comes as a welcome boon to cardiologists, surgeons, internists, and general practitioners who must consider referring their patients for such surgery. It presents a balanced and reasonable picture of the overall subject, in addition to containing important information on such topics as opera tive technique and economic impact. Dr. Miller has done an outstand ing job in bringing together in one text the important considerations related to the evaluation of patients, the natural history of coronary artery disease and the benefits and problems associated with bypass surgery.

Taschenbuch. Condizione: Neu. Neuware - What have been brought together in these volumes are works represent ing a variety of modern quantitative studies on a select group of marine organisms. Some of the species studied here represent basic biological ex perimental subjects-in some cases, marine versions of the white rat and pigeon-that are being used for a wide range of studies. Other species studied were virtually unknown as experimental animals. The authors have studied their animals in considerable depth, often in both the field and the laboratory. It is this cross reference between real life and the artificial but controlled conditions of the laboratory which gives us the necessary understanding, and ultimately the means, for improving our rapidly deteriorating environment, a must for man's survival, maintenance, and improvement of the quality of living standards. A direct outgrowth of a AAAS symposium entitled 'Recent Advances in the Behavior of Marine Organisms' held in December 1966, these vol umes include a reasonable balance between review and original unpublished research. Of the many persons who have made these volumes possible, we wish to especially thank Nancy Fish, Lois Winn, Mabel Trafford, and Deborah Brennan. The latter two accomplished most of the final editorial work. The personnel of Plenum Press were cooperative in all aspects of our rela tionship. Only the two editors are responsible for defects in the volumes. We believe the papers presented are significant and will be of importance to members of the scientific community.

Taschenbuch. Condizione: Neu. Neuware - The present volume contains the edited transcript of a Totts Gap Colloquium held May 19-21, 1980 sponsored by the Muscular Dystrophy Association. The aim of the colloquium was to bring into focus data relating to cell membranes that might contribute to understanding the pathogenic mechanism of Duchenne muscular dystrophy. A major impediment to progress in understanding the patho genesis of muscular dystrophy has been the failure, so far, to identify the basic genetic defect. Pending the identification of the genetic lesion in Duchenne dystrophy and, in view of scattered but persistent indications of a basic membrane disturbance, it seemed worthwhile to explore in open dialogue the current state of knowledge of membrane morphology and chemistry with an eye to possible leads for further investigation. The participants, drawn from a variety of interested disciplines, attempted to synthesize and reconcile their findings and to identify crucial areas of ignorance in need of exploration. For the most part they avoided specialized jargon and spoke in a language that could be understood by the rest of the group. Apart from providing a review of widely varying approaches to the study of the composition and behavior of cell membranes, the discussions brought together current think~g on strategies and approaches to the study of the pathogenesis of muscular dystrophy. Already the personal contacts made at the colloquium have led to new inter-institutional collabora tive investigations.

Taschenbuch. Condizione: Neu. Neuware - In the early 1960s, Dr. Alexander G. Karczmar, Professor of Pharmacology and Experimental Therapeutics at the Stritch School of Medicine of the Medical Center at Loyola University of Chicago, was confronted with a certain technical problem concerning his studies of synaptic transmission by means of microelectrode methods. He thought that the problem might be resolved if he could interest a microelectrode expert such as Dr. Kyozo Koketsu in his studies. Dr. Koketsu was a past member of the Faculty of the Kurume University School of Medicine who as a Research Fellow at the Australian National University had helped Sir John Eccles, subse quently a Nobel Prize winner, in developing microelectrode procedures. After further considering the matter, Dr. Karczmar was pleasantly sur prised to discover that by coincidence Dr. Koketsu was his neighbor, serving at that time as a Research Professor at the Neuropsychiatry Institute of the University of Illinois, College of Medicine of Chicago. This was the beginning of a long relationship, as Dr. Koketsu joined Dr. Karczmar at Loyola as Professor of Pharmacology and Therapeutics and Director of the Neurophysiology Laboratory at the Stritch School of Medicine. It was not long before Dr. Syogoro Nishi-Dr. Koketsu's former colleague on the Faculty of Medicine at Kurume University, and at that time a Research Fellow in Neurophysiology at the Rockefeller Institute in New York joined Drs. Koketsu and Karczmar at Loyola. Although in due time Drs.

Taschenbuch. Condizione: Neu. Neuware - To accomplish these objectives, the book is Body surface electrocardiographic mapping is not a new technique. It is one initially de divided into five sections. In Part I, the deve veloped many decades ago, but it has only lopment of electrocardiographic leads as well as recently matured into a powerful tool for surface mapping is viewed from an historical studying the cardiac electrical field. This book perspective. This is followed in Part II by a is intended to review, both critically and in review of the fundamental physiologic and detail, the applications of this unique method biophysical principles of electrocardiography in both clinical and experimental environments. and a discussion of basic mapping techniques. A comprehensive description of reported re Applications of these methods to the normal sults is, however, only a first goal. An equally and the abnormal heart are then presented in important objective is to explore the elec Parts III and IV, respectively. Finally, the trophysiologic and biophysical bases for the work concludes (Part V) with a consideration empirically observed electrocardiographic pat of possible future directions that body surface terns. It is only after considering these basic mapping may follow. The final result is, hope foundations that the values and the limitations fully, a thorough statement defining the cur of any electrocardiographic method can be rent s~atus of body surface electrocardiographic understood. This is particularly true for body mappmg.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is for the most part made up of the invited papers presented at the International Conference on Applica tions of the Kdssbauer effect, held at Aye1eth Hashahar, Israel, in August 1972. The purpose of the conference was to review perspec tives in MHssbauer spectroscopy from the point of view of applications in various fields of science - mainly physics, chemistry, and biology. It was hoped that the bringing together of scientists who work in different disciplines but use a common tool would encourage interdisciplinary re search and widen the horizon of the individual researcher. Both these features have been an important and unique characteristic of Kdssbauer research in the past decade. Accordingly, the main papers were presented in the following areas: magnetic properties of solids, applications to in organic chemistry, biochemical studies, amorphous systems, metal alloys, advances in high-resolution studies, and the new techniques for studying recoil-free spectra from isolated atoms in inert materials. A special panel discussion was devoted to the subject of phase transitions. Recent years have witnessed a rapid growth in the use of X-ray photoelec tron spectroscopy for the study of the physics and chemistry of solids. A report on this area of research and its rela tion to Kdssbauer studies has been included. 268 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux. 512 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Knowledge Services Management looks at the transformation of the traditional workplace into a quasi-internal market environment where work activities in knowledge services are organized around clusters of similar or complementary knowledge stocks to address particular types of customer-clients priorities. The book explores a new internal market structure for these service organizations and the implications this presents for managers and scholars in the 21st century workplace. By adopting an internal market perspective, the book develops new organizational forms outside the traditional hierarchical paradigm, which is ill-suited for the emerging knowledge workplace, in order to effectively manage emerging knowledge services. The indispensable role of customer/client in the operations of these organizations is examined, as is the creation of the 'Proventure Workplace', a work environment which accentuates jobs requiring rich cognitive skills for continuing innovation and creativity. 200 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -He who knows and knows that he knows is wise; follow him. -ANCIENT PROVERB During a long career of public service as a government procurement and contracting official, I am still surprised to find big, successful corporations making the same mistakes that neophytes in government contracting mak~. And this is particularly true in the matter of writing proposals, which are the crucial element in most major procurement awards. It's true enough, as many suspect, that the big, well-known company has something of an edge over the smaller, lesser-known company com peting for any given government contract-psychologically, at least: The typical government executives, whether contracting officials or program managers, tend to have a bit more faith in the ability of the large company to carry out the program successfully. All things being equal, then, the big company is more likely to get the nod. However, because the large companies are well aware of that, many tend to become 'fat, dumb, and happy'-they try to coast or rest on their laurels. That is, they get careless about making a strong enough case for themselves in writing their proposals. And when they lose, often to smaller companies, they are both puzzled and outraged. They have for gotten that all government procurement is a competition-usually both technical and cost competition-and that the 'little guy' can win against the 'big guy,' if he tries hard enough. And especially if the bigger guy is a bit careless and does not put out his best effort. 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the most well-known of all network optimization problems is the shortest path problem, where a shortest connection between two locations in a road network is to be found. This problem is the basis of route planners in vehicles and on the Internet. Networks are very common structures; they consist primarily of a nite number of locations (points, nodes), together with a number of links (edges, arcs, connections) between the locations. Very often a certain number is attached to the links, expressing the distance or the cost between the end points of that connection. Networks occur in an extremely wide range of applications, among them are: road networks; cable networks; human relations networks; project scheduling networks; production networks; distribution networks; neural networks; networks of atoms in molecules. In all these cases there are 'objects' and 'relations' between the objects. A n- work optimization problem is actually nothing else than the problem of nding a subset of the objects and the relations, such that a certain optimization objective is satis ed. 196 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -High pressure science is a rapidly growing diverse fi. e1d. The high pressure technique has become a powerful tool for both the study and preparation of materials. In spi. te of the many high pressure conferences held in recent years, I felt that there was a need for scientists within a well-defined area (not bound merely by the common experimental technique) to meet in an atmosphere conducive to frank exchange and close interaction. In this spirit, the Cleveland State University hosted such a conference from July 20 to 22, 1977, in which the physics of solids under high pressures and at low tempera tures was specifically examined. Both the original and review papers presented at the conference and the candid discussions following their presentations appear in this volume. They clearly cover a rather complete spectrum of current research in the physics of solids at high pressures and low temperatures. I wish to thank the National Aeronautics and Space Administra tion, the Office of Naval Research and the National Science Founda tion for their financial support of the conference. In addition, I wish especially to thank Steinar Huang for his unceasing assistance in arranging this conference. I also wish to thank him and Francis Stephenson for their assistance in preparing this book. C. W. Chu, Chairman, International Conference on High Pressure and Low Temperature Physics v Contents HYDROGEN AND METAL-HYDRIDES (Chairman: I. Spain) PROSPECTS FOR METALLIC HYDROGEN 1 A. L. 616 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the Proceedings of the NATO Advanced Research Workshop on 'Growth and Optical Properties of Wide Gap II-VI Low Dimensional Semiconductors', held from 2 - 6 August 1988 in Regensburg, Federal Republic of Germany, under the auspices of the NATO International Scientific Exchange Programme. Semiconducting compounds formed by combining an element from column II of the periodic table with an element from column VI (so called II-VI Semiconductors) have long promised many optoelectronic devices operating in the visible region of the spectrum. However, these materials have encountered numerous problems including: large number of defects and difficulties in obtaining p- and n-type doping. Advances in new methods of material preparation may hold the key to unlocking the unfulfilled promises. During the workshop a full session was taken up covering the prospects for wide-gap II-VI Semiconductor devices, particularly light emitting ones. The growth of bulk materials was reviewed with the view of considering II-VI substrates for the novel epitaxial techniques such as MOCVD, MBE, ALE, MOMBE and ALE-MBE. The controlled introduction of impurities during non-equilibrium growth to provide control of the doping type and conductivity was emphasized. 364 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The North Atlantic Treaty Organization (NATO) established the 'Committee on the Challenges of Modern Society' (CCMS) at the November 1969 meeting of the North Atlantic Council. The CCMS was charged with developing meaningful environmen tal and social programs that complement other international pro grams, and with showing leadership, first, in solution of exist ing problems and, second, in development of long-range goals for environmental protection in the NATO sphere of influence and in other countries as well. A first Pilot Study on Air Pollution was initiated by the CCMS at its inaugural meeting in December 1969. It resulted in documents about the definition of criteria for the effects of air pollutants as well as the development of assess ment methods for air quality in urban areas. A second Air Pollution Pilot Study (1975-1979) worked out the basics for setting up assessment methods for emissions inven tories, techniques for the practical application of meteorologi cal diffusion models as well as the development of guidelines for an Air Quality Management System (AQMS). Within this second Air Pollution Pilot Study attention to modelling concentrated on the Gaussian Plume Model. A third Pilot Study on Air Pollution Control Strategies and Impact Modelling then was initiated in 1979 and started in 1980. 292 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The contents of this book reflect a symposium held in honor of Professor Herman Kalckar's seventy-fifth birthday. His impact on the history of biochemistry is reflected by the diversity of the contributions of his former students and friends. Speakers came from Asia, Europe, and the United States to discuss both procaryotes and eukaryotes. The unifying theme was the cell membrane, both its organization and its function. Ektobiology, a topic that has held the attention of Professor Kalckar for many years, was clearly defined as a central topic in biology. This subject deals with the key structure whereby the cell interacts with the outside world and which, in a sense, defines the boundary between what is the cell and what is not. Topics discussed include the biogenesis of membrane proteins, sugars and lipids, the role of membrane components in osmoregula tion, and mechanisms of nutrient transport. Of great interest is the system for surface recognition evolved in vertebrates, exemplified by the HLA system of man. Neoplasia causes changes in the cell membrane that may be of significant future potential in the diagnosis and treatment of malignancies as well as in the understanding of the process of transformation. The changes in glycosphingolipids and carbohydrate antigens in relation to oncogenesis are detailed. I should like to recognize Doctors Kurt J. Isselbacher, Phillips W. Robbins, Victor Ginsburg, and Hiroshi Nikaido for their ,assistance in organizing the symposium. Ms. Jean Brumbaugh deserves special thanks for putting this book together. 312 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Within the tradition of meetings devoted to potential theory, a conference on potential theory took place in Prague on 19-24, July 1987. The Conference was organized by the Faculty of Mathematics and Physics, Charles University, with the collaboration of the Institute of Mathematics, Czechoslovak Academy of Sciences, the Department of Mathematics, Czech University of Technology, the Union of Czechoslovak Mathematicians and Physicists, the Czechoslovak Scientific and Technical Society, and supported by IMU. During the Conference, 69 scientific communications from different branches of potential theory were presented; the majority of them are in cluded in the present volume. (Papers based on survey lectures delivered at the Conference, its program as well as a collection of problems from potential theory will appear in a special volume of the Lecture Notes Series published by Springer-Verlag). Topics of these communications truly reflect the vast scope of contemporary potential theory. Some contributions deal with applications in physics and engineering, other concern potential theoretic aspects of function theory and complex analysis. Numerous papers are devoted to the theory of partial differential equations. Included are also many articles on axiomatic and abstract potential theory with its relations to probability theory. The present volume may thus be of intrest to mathematicians speciali zing in the above-mentioned fields and also to everybody interested in the present state of potential theory as a whole. 380 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high-resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 22 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invaluable reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts. 516 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present volume is based on the proceedings of the 12th Workshop of the INFN ELOISATRON Project, held at the 'Ettore Majorana' Centre for Scientific Culture (EMCSC), Erice (frapani), Sicily, Italy, in the period September 15-20, 1990. The proceedings deal with the presentation of 'New Technologies for Supercolliders'. Three new energy frontiers (16,40 and 200 TeV) are now opened up for the future of Subnuclear Physics. Basic problems above the Fermi-energy are crowding up: but no one knows the energy levels needed for their solution. This is why the technology for experiments with the new generation of Supercolliders needs to be pursued having in mind the problems which are of common interest in the three energy frontiers. The primary purpose of the Workshop was to contribute towards the highest energy limit in the search for new instruments and new technologies. Furthermore, the present status and performances of various detector technologies were reviewed. The possible options for a powerful apparatus whose goal would be the discovery of the top, Higgs and SUSY particles in a very high energy, high rate environment, were finally analysed. The Workshop was sponsored by the Italian National Institute for Nuclear Physics (INFN), the Italian Ministry of Education, the Italian Ministry of Scientific and Technological Research and the Sicilian Regional Government. We are thankful to the staff of EMCSC for their efficient and warm support. 404 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The ground-state of molecular oxygen, O , is essential to many 2 indispensible metabolic processes of all aerobic life forms ranging from prokaryotes, protists, plants, and fungi to animals. Research by mammalian toxicologists and clinicians has unravelled persua sive evidence that O dependence imposes universal toxicity to all 2 aerobic life processes. The basis of this paradox is that one-electron reduction of O2 generates the superoxide anion free radical, 0;-, from numerous biological sources; for example, redox-active autoxidizable molecules such as catecholamines, oxidoreductases, and subcellular organelles such as mitochondria, endoplasmic reti'C ulum (microsomes), nuclei, and chloroplasts. Oxygen is also acti vated in biologically relevant photosensitizing reactions to highly re active singlet oxygen, 10 , 2 In all biological systems, 0;- undergoes further reduction to H 0 2 2 via Fenton reaction to the hydroxyl radical, OH. These, and some other forms of activated O , constitute reactive oxygen species (ROS) 2 and/or metabolites (ROM). Both 'OH and 10 are the most reactive 2 forms of ROS known and among their deleterious reactions are ox idation of proteins, DNA, steroidal compounds, and peroxidation of the cell membrane's unsaturated lipids to form unstable hydro peroxides. Their many breakdown products include malondialde hyde and hydroxynonenals that are themselves highly reactive and threaten cellular integrity and function. More importantly, they de compose to free radicals that can continue to propagate the vicious lipid peroxidation chain reaction. This is the so-called endogenous oxidative stress with which all aerobic organisms must cope. 480 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Alzheimer's disease, stroke and Parkinson's disease are the most prevalent brain diseases in the elderly. The psychiatric and behavioural consequences of these and other brain disorders contribute greatly to the decline in function of these patients, often leading to greater suffering and a decreased quality of life, placement in institutions and increased stress on the family and other caregivers. The authors in this book discuss the psychiatric consequences of brain disease in the elderly with a particular focus on the management of these disorders. We have tried to keep the content of this book clinically relevant throughout by using a series of case examples and by emphasizing the various treatment strategies and forms of management available to the health care professional. In attempting to understand these disorders, it is important to place equal emphasis on biological, psychological and social factors. Because of the complexity and chronicity of these conditions, multidisciplinary intervention is crucial. We believe that this book will be helpful to all those working with the elderly, whether in the community or in the institution. This includes physicians, nurses, social workers, occupational therapists, psychologists and all those working with this patient population. 228 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lewis Thomas has suggested that 'Perhaps the inflammatory reaction should be regarded as a defense of an individual against all the rest of nature, symbolizing his individuality and announcing his existence as an entity. ' Provision of these symbols and announcements is the task of various mediators of inflammation and this volume has been designed to present our current understanding of their biochemistry, cellular origins, pharmacology, and role in pathology. Unlike other volumes of collected papers, this book did not result from a specific conference or symposium at which each contributor presented his own, narrowly framed research experience. Rather, each of the chapters represents, in the form of a general review, a summary of our knowledge of the mediators and the mecha nisms by which they are released to launch the inflammatory response. Much effort has been taken to insure that the often conflicting terminology in this field is defmed in detail: many synonyms (e. g. , of the properdin system or the alternate pathway of complement activation) have been repeatedly presented, in order to avoid confusion. Although each of the contributors is actively engaged in the field of inflammation, few text figures or tables of ongoing research have been included; the overall aim was to provide a volume readily accessible to workers in other areas as well as to the general reader. 220 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the last decade, the rapid growth of knowledge in the field of fluid mechanics and heat transfer has resulted in many significant ad vances of interest to students, engineers, and scientists. Accordingly, a course entitled 'Modern Developments in Fluid Mechanics and Heat Transfer' was given at the University of California to present significant recent theoretical and experimental work. The course consisted of seven parts: I-Introduction; II-Hydraulic Analogy for Gas Dynamics; 111- Turbulence and Unsteady Gas Dynamics; IV-Rarefied and Radiation Gas Dynamics; V-Biological Fluid Mechanics; VI-Hypersonic and Plasma Gas Dynamics; and VII-Heat Transfer in Hypersonic Flows. The material, presented by the undersigned as course instructor and by various guest lecturers, could easily be adapted by other universities for use as a text for a one-semester senior or graduate course on the subject. Due to the extensive notes developed during the University of California course, it was decided to publish the material in three volumes, of which the present is the first. The succeeding volumes will be entitled 'Selected Topics in Fluid and Bio-Fluid Mechanics' and 'Introduction to Steady and Unsteady Gas Dynamics.' Finally, I must express a word of appreciation to my wife Irene and to my children, Wellington Jr. and Victoria, who made it possible for me to write and edit this book in the very quiet atmosphere of our home. 404 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is a pleasure to any author to enlarge the circle of his readers. Naturally this is a pleasure to me. At the same time, however, misgivings arise: whether these pages will con vey to the circle of new readers the thoughts that excite the author. Science is advancing rapidly in our day. It is already apparent that many things in the book should have been stated differently. I have tried to make additions to the English-language edition in such a way that they do not require great alteration of the text. I ask my new readers to remember that this book was written primarily for my fellow countrymen and that, because of this, some chapters contain descriptions of regions little known to you and information on the USSR almost unknown from other publications. I hope that, despite this, geologists who read the English-language edition will find something of interest to themselves in it and that their labor will not have been in vain. Yu. M. Sheinmann Institute of Phys ics of the Earth Moscow v PREFACE The study of endogenetic processes has long pushed us into investigation of ever deeper parts of the earth. Not long ago all attention was focused on depths where ore deposits appear, where metamorphic and igneous rocks, which later become exposed at the surface, are formed, where granites originate. 184 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The literature of medicine continues to expand at a remarkable pace. The number of papers and monographs published has increased dramatically in the past five years. Nowhere has this increase been as dramatic as in the field of acute and chronic hepatitis. Why then should there be still another book Despite the sheer volume of words published, it is still difficult to find in anyone volume a compilation of all of the most significant work. Most mono graphs have considered either chronic or acute hepatitis, not both. Few works have addressed both the clinician and the basic scientist. This book addresses both of these audiences and considers both of these diseases. It was designed to provide an authoritative but concise assessment of our changing concepts of acute and chronic hepatitis. It covers what is currently known and, based on the most convincing research, believed about these diseases. To fulfill this ambitious goal, only authors with international reputations in their fields of expertise were invited to contribute. In the evolution of our current thoughts on the pathogenesis and manage ment of acute and chronic hepatitis, our ideas have changed several times. This book presents the facts as they are known today and, in areas where all the facts are not established, presents the well-founded opinions of those considered to be authorities. The authors present established and usually confirmed data and do not deal extensively with areas of speculation or unconfirmed material. 360 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In many areas of physics, such as astrophysics, solid-state physics, nuclear physics and particle physics, a major outstanding problem is a better understanding of corre lation phenomena. While in most cases the average properties of a system are rather well understood, the correlations and the resulting clustering are poorly understood. They are reflections of the force mediating the interaction among the constituents and play essential roles in determining the structure of a physical system. At the largest scales, in astrophysics, it has recently been realized that there are huge voids in space and almost all matter is concentrated on filaments, raising interesting questions concerning the origin of this clustering of matter. In nuclear physics corre lation phenomena are important in all its subfields. It has been realized that so-called fluctuations in the one-particle density, which are a manifestation of nucleon-nucleon correlations, are crucial. These are important for an understanding of heavy-ion reac tions. This is the subject of modern quantum transport theories. Correlations are also crucial in the description of the high momentum components as observed in quasi-elastic knock-out reactions. 280 pp. Englisch.