Springer us mai 1990 (15 risultati)
Lingua: Inglese
Editore: Springer Us Mai 1990, 1990
Serie: Libro 63 di 253 - Developments in Cardiovascular Medicine
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Buch. Condizione: Neu. Neuware - The Symposium on New Drugs provides for an annual forum for academic investigators, research and development personnel from the pharmaceutical and related health care industries, and members of the Food and Drug Administration to discuss important clinical research issues. The Tenth Annual Sympos…ium on New Drugs addressed the problem of whether it was still appropriate to approve antihypertensive agents soley on the endpoint of lowering cuff blood pressure. The initial discussions at this symposium related to the approaches and methods to studying antihypertensive agents. Dr. William Frishman provided a detailed list of the new approaches to the treatment of hypertension and pointed out the many new concepts that are currently active in the development of many new antihypertensive agents. Dr. William White detailed the growing importance of ambulatory blood pressure monitoring to define hypertension and to determine the change in blood pressure due to pharmacologically active agents. Dr. Jay Cohn pointed out the flaws in using cuff blood pressure and detailed the potential virtues of using vascular compliance to identify patients requiring treatment for hypertension. Dr. Thomas Pickering also discussed the potential value of evaluating changes in left ventricular hypertrophy a finding which identifies high risk patients who need to be included in clinical trials. Dr. Michael Weber detailed the issues and suggested refinements in the approaches to clinical trial designs for antihypertensive agents and Dr. Raymond Lipicky discussed the definition of dose-duration and the role of non-Mem and Peak/Through measurements in defining an antihypertensive drug effect.
Lingua: Inglese
Editore: Springer Us Mai 1990, 1990
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 314,64
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Buch. Condizione: Neu. Neuware - Bone marrow transplantation has emerged as a major form of treatment for a broad range of human diseases. Marrow transplantation has many unique biologic features and its principles differ markedly from the transplantation of solid organs. This volume overviews the present status of bone marrow t…ransplantation and summarizes recent progress and controversies. Ad vances in defining the underlying biology of marrow transplantation are discussed. The current status of several major clinical problem areas are reviewed, including engraftment, acute and chronic graft-versus-host dis ease, immunodeficiency, and opportunistic infections. The therapeutic role of allogeneic and autologous bone marrow transplantation is discussed, and results are compared with alternative therapies. lX List of contributors ANASETII, CLAUDIO, M. D. , Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, Washington 98104 APPELBAUM, FRED, M. D. , Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, Washington 98104 ARMITAGE, JAMES 0. , M. D. , Department of Internal Medicine, Univer sity of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska 68105 BEATIY, PATRICK G. , M. D. , Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, Washington 98104 BIERMAN, PHILIP J. , M. D. , Department of Internal Medicine, Univer sity of Nebraska Medical Center, 42nd and Dewey Avenue, Omaha, Nebraska 68105 BUTTURINI, ANNA, M. D. , Department of Pediatrics, University of Parma School of Medicine, Parma, Italy CHAMPLIN, RICHARD, M. D.
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Buch. Condizione: Neu. Neuware - The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, is an im portant responsibility of physicians. The history of medicine is characterized by the authoritarianisms of teachers and of organizations gi…ving way to the clinical experience of physicians; authoritarian dictum was replaced by case report and then by case series. As physicians learned to substitute the analysis of data for the inconsistencies of dictums and anecdotes, the problems of the case series as an investigative tool became more evident: patient selection criteria, measurements of outcome, significance of results, and extrapolation of conclusions to the community of patients. In response to these issues, the methodology of the controlled clinical trial has evolved and with it the instru ments of study design and of biostatistics as aids to study design and data analysis. The medical - surgical armamentarium has evolved from being dependent solely upon the observations and conclusions of a skilled clinician to being constructed upon the systematic collection and evaluation of data by a team of skilled clinicians and their statistical colleagues: this is the controlled clinical trial. During the past two decades, the evaluation of clinical approaches to pre vention and therapy has become particularly important to clinicians concerned with nervous system dysfunction. There has been and continues to be an explosion of information from the basic neurosciences and from the applica tion of biotechnology to the nervous system.
Lingua: Inglese
Editore: Springer Us Mai 1990, 1990
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 432,18
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Buch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary…reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many times there are subjects which demand further explanations and guid ance written about them. Such is the case with SGML, the Standard Generalized Markup Language; and ISO Standard published in October, 1986 under the number 88…79. There have been many conferences given on this topic, world-wide, as the interest in SGML exists in Europe, the US, Australia and Japan. This book is the first which contains information not only on ISO 8879 itself, but many helpful hints and ideas on developing SGML, applications and discussions of the current software written to be conforming to the ISO standard. 'Ibis book is critical for any end-user and application developer to understand the many issues neccessary to develop SGML implementations (software selection is one of the topics discussed) and SGML applications. A number of examples of the applications of SGML in various situations are discussed and one can expect that the book will stimulate further discussion of these. This book is a practical guide to various components of the language and the author's experience in development and worldng with SGML in his position as leader of the text processing section at CERN ensures that the guidance is based on practical first-hand experience at an installation with a large number of end-users of very varied experience. 328 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Philosophy and psychopathology have more in common than philosophers, psychiatrists and clinical psychologists might think. Three fields of inquiry come to mind: (1) Questions about the scientific status of psychopatho logical stat…ements and claims, (2) ethical questions, and (3) problems regarding the question of how to account for something like a disordered mind. While the first two domains have frequently been addressed in articles and debates (think of the mind-body problem and the problem of institutionalization versus self-determination as examples of issues in the two fields), the question of how the mind should be conceived in order for psychopathology to work best has seldom been discussed. The present volume focuses on this question. Perception, thought, affect, will, and the like are terms which made their way from philosophy into psychology, and into present psychiatry, where disturbances of these 'faculties' or 'functions' are believed to form the most basic part of symptomatology. While these terms and many others that are used to refer to symptoms of mental disorder (such as 'self', 'consciousness', 'drive', and 'identity') may seem to be purely descriptive and theoretically 'innocent', they are packed with implicit assumptions, theoretical concepts, and sometimes dogmatic postulates. 260 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Rarely if ever have the political, economic, and military foundations of the Western Alliance been in such a state of flux. Walter Laqueur and Leon Sloss, therefore, deserve credit not just for the quality of the analysis in this superb book…but also for the timeliness of its appearance. As Laqueur says in his chapter 'Touring the Western European Defense Hori zon,' if the likely development of European defense policies is not particularly reassuring, at least it gives no grounds for despair. The list of problems we face is a daunting one. First there is the spiralling cost of defense expenditures, particularly in the absence of significant NATO or inter-European cooperation. This is particu larly serious in light of the reluctance to increase, or even maintain, current expen ditures in the midst of Mikhail Gorbachev's 'peace offensive' and the extraordinary changes in Eastern Europe, both of which have had a dramatic impact on Western public opinion. There is also a problem in the perceived relative economic decline of the United States vis-a-vis Western Europe and Japan, which only exacerbates calls to reduce the number of American troops in Europe. Other dangers to the political cohesion and military credibility of the alliance include demographic trends that threaten current manpower levels, transatlantic acrimony over the burden-sharing issue, and political pressures (particularly in West Germany) toward denucleariza tion and even neutralism.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 234 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Rarely if ever have the political, economic, and military foundations of the Western Alliance been in such a state of flux. Walter Laqueur and Leon Sloss, therefore, deserve credit not just for the quality of the analysis in this superb b…ook but also for the timeliness of its appearance. As Laqueur says in his chapter 'Touring the Western European Defense Hori zon,' if the likely development of European defense policies is not particularly reassuring, at least it gives no grounds for despair. The list of problems we face is a daunting one. First there is the spiralling cost of defense expenditures, particularly in the absence of significant NATO or inter-European cooperation. This is particu larly serious in light of the reluctance to increase, or even maintain, current expen ditures in the midst of Mikhail Gorbachev's 'peace offensive' and the extraordinary changes in Eastern Europe, both of which have had a dramatic impact on Western public opinion. There is also a problem in the perceived relative economic decline of the United States vis-a-vis Western Europe and Japan, which only exacerbates calls to reduce the number of American troops in Europe. Other dangers to the political cohesion and military credibility of the alliance include demographic trends that threaten current manpower levels, transatlantic acrimony over the burden-sharing issue, and political pressures (particularly in West Germany) toward denucleariza tion and even neutralism. 234 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Now, 25 years into our country's most recent 'women's movement' for equality, it is appropriate to reexamine the social and cultural experiences of women. Thanks to the media, researchers, clinicians, and the general public, all are aware… that women have been unable to realize many of their goals. At times, distress rather than satisfaction and rejection and disap pointment rather than contentment have been the result of the ongoing struggle of women to achieve change-the change in attitudes, behavior, and values necessary to broaden the personal choices and work options open to women. Nationally recognized authorities on several of the sociocultural issues addressed in this volume, the editors invited noted scholars and clinicians to study some of those issues particularly relevant to women. These include frequently neglected topics, such as the multiplicity of responsibilities of single women and the spectrum of mothering roles, and those more commonly discussed, such as the various roles and patterns in the family, work options and burdens, and interpersonal relationships. The volume provides insightful detail on two prominent and poignant problems of the 1980s-the causes and repercussions of homelessness and sexual life-styles. Such material may facilitate under standing and serve as a catalyst for positive action. 274 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Written by experts in the field and filled with the latest research data, this comprehensive work presents important information on the nutritional properties of fish oils for human health and the analysis of fatty acids. Included is info…rmation on the breakdown, production and refining of fatty acids, as well as the newest methods of analysis and fractionation of fish oil fatty acids. This book should be of interest to seafood industry personnel, researchers, nutritionists, food scientists, biochemists and chemists and scientists in the pharmaceutical industry using fish oil. 332 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Now, 25 years into our country's most recent 'women's movement' for equality, it is appropriate to reexamine the social and cultural experiences of women. Thanks to the media, researchers, clinicians, and the general public, all are aware tha…t women have been unable to realize many of their goals. At times, distress rather than satisfaction and rejection and disap pointment rather than contentment have been the result of the ongoing struggle of women to achieve change-the change in attitudes, behavior, and values necessary to broaden the personal choices and work options open to women. Nationally recognized authorities on several of the sociocultural issues addressed in this volume, the editors invited noted scholars and clinicians to study some of those issues particularly relevant to women. These include frequently neglected topics, such as the multiplicity of responsibilities of single women and the spectrum of mothering roles, and those more commonly discussed, such as the various roles and patterns in the family, work options and burdens, and interpersonal relationships. The volume provides insightful detail on two prominent and poignant problems of the 1980s-the causes and repercussions of homelessness and sexual life-styles. Such material may facilitate under standing and serve as a catalyst for positive action.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 274 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 160,49
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Written by experts in the field and filled with the latest research data, this comprehensive work presents important information on the nutritional properties of fish oils for human health and the analysis of fatty acids. Included is informat…ion on the breakdown, production and refining of fatty acids, as well as the newest methods of analysis and fractionation of fish oil fatty acids. This book should be of interest to seafood industry personnel, researchers, nutritionists, food scientists, biochemists and chemists and scientists in the pharmaceutical industry using fish oil.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 213,99
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biologi…cal anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. 448 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 213,99
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological…anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 448 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 320,99
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A revised and updated version of Behavioral consultation (1977). A basic text for students and professionals interested in increasing consultation skills to assist parents, teachers and others to solve mental-health and educational proble…ms of children and youths. The orientation is behavioral, with 534 pp. Englisch.
