springer us mai 2018 (20 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book is open access under a CC BY-NC 2.5 license.The Gulf of Mexico is an open and dynamic marine ecosystem rich in natural resources but heavily impacted by human activities, including agricultural, industrial, commercial and coastal development. The Gulf of Mexico has been continuously exposed to petroleum hydrocarbons for millions of years from natural oil and gas seeps on the sea floor, and more recently from oil drilling and production activities located in the water near and far from shore. Major accidental oil spills in the Gulf are infrequent; two of the most significant include the Ixtoc I blowout in the Bay of Campeche in 1979 and the Deepwater Horizon Oil Spill in 2010. Unfortunately, baseline assessments of the status of habitats and biota in the Gulf of Mexico before these spills either were not available, or the data had not been systematically compiled in a way that would help scientists assess the potential short-term and long-term effects of such events.This 2-volume series compiles and summarizes thousands of data sets showing the status of habitats and biota in the Gulf of Mexico before the Deepwater Horizon Oil Spill. Volume 2 covers historical data on commercial and recreational fisheries, with an analysis of marketing trends and drivers; ecology, populations and risks to birds, sea turtles and marine mammals in the Gulf; and diseases and mortalities of fish and other animals that inhabit the Gulf of Mexico.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 956 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume providesa sound basis for the molecular investigation of NLR function in health anddisease. Chapters focus on of innate immune receptors, ¿atypical¿inflammasomes, biochemical and novel bioluminescencetechniques for the measurement of IL-1bbioluminescent probe, biochemical and microscopytechniques, techniques to measure caspase-1 activation, cellfree systems for the study of inflammasome function, and inflammasomeactivation. Written in the highly successful Methodsin Molecular Biology series format, chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-stepreadily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Authoritativeand cutting-edge, NLR Proteins: Methodsand Protocols aims to ensure successful results in the further study ofthis vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 272 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This far-reaching volume analyzes the social, cultural, political, and economic factors contributing to mental health issues and shaping treatment options in the Asian and Pacific world. Multiple lenses examine complex experiences and needs in this vast region, identifying not only cultural issues at the individual and collective levels, but also the impacts of colonial history, effects of war and disasters, and the current climate of globalization on mental illness and its care. These concerns are located in the larger context of physical health and its determinants, worldwide goals such as reducing global poverty, and the evolving mental health response to meet rising challenges affecting the diverse populations of the region. Chapters focus on countries in East, Southeast, and South Asia plus Oceania and Australia, describing: National history of psychiatry and its acceptance. Present-day mental health practice and services. Mental/physical health impact of recent social change. Disparities in accessibility, service delivery, and quality of care. Collaborations with indigenous and community approaches to healing. Current mental health resources, the state of policy, and areas for intervention. A welcome addition to the global health literature, Mental Health in Asia and the Pacific brings historical depth and present-day insight to practitioners providing services in this diverse area of the world as well as researchers and policymakers studying the region. 340 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book grew out of the need to provide students with a solid introduction to modern fluid dynamics. It offers a broad grounding in the underlying principles and techniques used, withsomeemphasis on applications in astrophysicsand planetary science. The bookcomprehensively coversrecentdevelopments, methods and techniques, including, for example, new ideas on transitions to turbulence (via transiently growing stable linear modes), new approaches to turbulence (which remains the enigma of fluid dynamics), and the use of asymptotic approximation methods, which can give analytical or semi-analytical results and complement fully numerical treatments. The authors also briefly discuss some important considerations to be taken into account when developing a numerical code for computer simulation offluidflows. Although the text is populated throughout with examples and problems from the field of astrophysicsand planetary science, the text is eminently suitable as a general introduction to fluid dynamics. It is assumed that the readers are mathematically equipped with a reasonable knowledge in analysis, including basics of ordinary and partial differential equations and a good command of vector calculus and linear algebra. Each chapter concludes with bibliographical notesin which the authors briefly discuss thechapter'sessential literature and give recommendations for further, deeper reading. Included in each chapter are a number ofproblems, some of themrelevant to astrophysicsand planetary science.The book is written for advanced undergraduate and graduate students, but will also prove a valuable source of reference for established researchers. 704 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The editors of this volume have compiled an important book that is a useful vehicle for important computational research - in the development of theoretical methodologies and their practical applications. Themes include new methodologies, state-of-the-art computational algorithms and hardware as well as new applications. This volume, Practical Aspects of Computational Chemistry IV, is part of a continuous effort by the editors to document recent progress made by eminent researchers. Most of these chapters have been collected from invited speakers from the annual international meeting: 'Current Trends in Computational Chemistry' organized by Jerzy Leszczynski, one of the editors of the current volume. This conference series has become an exciting platform for eminent Theoretical/Computational Chemists to discuss their recent findings and is regularly honored by the presence of Nobel laureates. Certainly, it is not possible to cover all topics related to the Computational Chemistry in a single volume but we hope that the recent contributions in the latest volume of this collection adequately highlight this important scientific area. 408 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This clinically focused and authoritative guide to managing End Stage Renal Disease (ESRD) patients provides the essentials of hemodialysis, peritoneal dialysis, and continuous therapies. Chapters cover the technical aspects of delivering dialysis therapy, clinical care of patients on dialysis and the evaluation and management of common complications of kidney failure in patients of dialysis - including anemia, bone disease and hypertension. Authored by worldwide leading experts in the field, this book is an invaluable resource for nephrologists and other healthcare professionals involved in dialysis treatment or caring for the ESRD patient. 304 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The interest in 'biomarkers' seen across a spectrum of biomedical disciplines reflects the rise of molecular biology and genetics. A host of 'omics' disciplines in addition to genomics, marked by multidimensional data and complex analyses, and enabled by bioinformatics, have pushed the trajectory of biomarker development even further. They have also made more tractable the complex mappings of genotypes to phenotypes - genome-to-phenome mapping - to which the concept of a biomarker is central.Genomic investigations of the brain are beginning to reveal spectacular associations between genes and neural systems. Neural and cognitive phenomics are considered a necessary complement to genomics of the brain. Other major omics developments such as connectomics, the comprehensive mapping of neurons and neural networks, are heralding brain maps of unprecedented detail. Such developments are defining a new era of brain science. And in this new research environment, neural systems and cognitive operations are pressed for new kinds of definitions - that facilitate brain-behavioral alignment in an omics operating environment. This volume explores the topic of markers framed around the constructs of cognitive and neural systems. 'Neurophenotype' is a term adopted to describe a neural or cognitive marker that can be scientifically described within an associative framework - and while the genome-to-phenome framework is the most recognized of these, epigenetics and non-gene-regulated neural dynamics also suggest other frameworks. In either case, the term neurophenotype defines operational constructs of brain-behavioral domains that serve the integration of these domains with neuroscientific and omics models of the brain. The topic is critically important to psychiatry and neuropsychology: Neurophenotypes offer a 'format' and a 'language' by which psychiatry and neuropsychology can be in step with the brain sciences. They also bring a new challenge to the clinical neurosciences in terms of construct validation and refinement. Topics covered in the volume include:Brain and cognition in the omics eraPhenomics, connectomics, and Research Domain CriteriaCircuit-based neurophenotypes, and complications posed by non-gene regulated factorsThe legacy of the endophenotype concept - its utility and limitationsVarious potential neurophenotypes of relevance to clinical neuroscience, including ResponseInhibition, Fear Conditioning and Extinction, Error Processing, Reward Dependence and Reward Deficiency, Face Perception, and Language PhenotypesDynamic (electrophysiological) and computational neurophenotypesThe challenge of a cultural shift for psychiatry and neuropsychology The volume may be especially relevant to researchers and clinical practitioners in psychiatry and neuropsychology and to cognitive neuroscientists interested in the intersection of neuroscience with genomics, phenomics and other omics disciplines. 328 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition synthesizes the emerging knowledge base on the diversity of stepfamilies, their inherent concerns, and why so relatively little is still known about them. Its extensive findings shed needed light on family arrangements relatively new to the literature (e.g., cohabitating stepparents), the effects of these relationships on different family members (e.g., stepsiblings, stepgrandparents), the experiences of gay and lesbian stepfamilies, and the stigma against non-nuclear families. Coverage reviews effective therapeutic and counseling interventions for emotional, familial, and social challenges of stepfamilies, as well as the merits of family education and self-help programs. The authors explore prevailing myths about marriage, divorce, and stepfamily life while expanding the limits of stepfamily research.Among the topics included:-The cultural context of stepfamilies.-Couple dynamics in stepfamilies.-Gay and lesbian couples in stepfamilies. -The dynamics of stepparenting. -Siblings, half-siblings, and stepsiblings. -Effects of stepfamily living on children.-Clinical perspectives on stepfamily dynamics.For researchers and clinicians who work with families, it enriches the literature as it offers insights and guidelines for effective practice as well as possible avenues for future research. 360 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume includes a series ofprotocols focused on mitotic spindle assembly and function. The methods coveredin this book feature a broad range of techniques from basic microscopy to thestudy of spindle physiologies relevant to cancer. These methods can be appliedto diverse model systems that range from the cell-free Xenopus eggextract system to the moss Physcomitrella patens, in an effort todemonstrate the key contributions made by researchers using multiple modelorganisms. Chapters in The Mitotic Spindle: Methods and Protocols integrate cutting-edge technologies that have only become available due to thecross-disciplinary efforts, such as ATP analogue sensitive inhibition ofmitotic kinases. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topicslists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips ontroubleshooting and avoidingknown pitfalls.Thorough and informative, TheMitotic Spindle: Methods and Protocols, is a valuable resource forresearchers who are new to mitosis or are already experts in the field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 440 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume provides a wide rangeof protocols used in studying the nuclear envelope, with special attention tothe experimental adjustments that may be required to successfully investigatethis complex organelle in cells from various organisms. The Nuclear Envelope:Methods and Protocols is divided into five sections: Part I ¿ Nuclear EnvelopeIsolation; Part II ¿ Nuclear Envelope Protein Interactions, Localization, andDynamics; Part III ¿ Nuclear Envelope Interactions with the Cytoskeleton; PartIV ¿ Nuclear Envelope-Chromatin Interactions; and Part V ¿ Nucleo-CytoplasmicTransport. Many of the modifications discussed in this book have only beencirculated within laboratories that have conducted research in this field formany years. Written in the highly successful Methods in Molecular Biologyseries format, chapters include introductions to their respective topics, listsof the necessary materials and reagents, step-by-step, readily reproduciblelaboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 540 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This handbook focuses on Data Envelopment Analysis (DEA) applications in operations analytics which are fundamental tools and techniques for improving operation functions and attaining long-term competitiveness. In fact, the handbook demonstrates that DEA can be viewed as Data Envelopment Analytics.Chapters include a review of cross-efficiency evaluation; a case study on measuring the environmental performance of OECS countries; how to select a set of performance metrics in DEA with an application to American banks; a relational network model to take the operations of individual periods into account in measuring efficiencies; how the efficient frontier methods DEA and stochastic frontier analysis (SFA) can be used synergistically; and how to integrate DEA and multidimensional scaling.In other chapters, authors construct a dynamic three-stage network DEA model; a bootstrapping based methodology to evaluate returns to scale and convexity assumptions in DEA; hybridizing DEA and cooperative games; using DEA to represent the production technology and directional distance functions to measure band performance; an input-specific Luenberger energy and environmental productivity indicator; and the issue of reference set by differentiating between the uniquely found reference set and the unary and maximal types of the reference set.Finally, additional chapters evaluate and compare the technological advancement observed in different hybrid electric vehicles (HEV) market segments over the past 15 years; radial measurement of efficiency for the production process possessing multi-components under different production technologies; issues around the use of accounting information in DEA; how to use DEA environmental assessment to establish corporate sustainability; a summary of research efforts on DEA environmental assessment applied to energy in the last 30 years; and an overview of DEA and how it can be utilized alone and with other techniques to investigate corporate environmental sustainability questions. 520 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970's. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. But it is much more than a reference manual - it is a substantial physiological and mathematical treatise in its own right. It also has a wide applicability - there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the 'black box' behavior of a system The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a 'black box' system. Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world's literature on the topic and to provide in one place the wealth of important discoveries, both physiological and clinical, enabled by the technique. 344 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Many breakthroughs in biological research and translational healthcare advancements have been achieved by studying the response of biological systems to extreme environments. The spaceflight platform provides a unique environment where researchers can explore fundamental questions into cellular and molecular response mechanisms to unveil novel insight into human health and disease. Since the physical force of gravity has shaped the architecture of all biological systems on our planet, spaceflight provides the opportunity to see life in a new adaptational mode - in response to reduced gravity. This enables investigations into the effects of the microgravity environment and associated changes in mechanical forces on mammalian cells/tissues and microbial pathogens, to bring novel insight into disease mechanisms, which are not discernable using conventional experimental approaches.Research using spaceflight platforms represents a paradigm shift in how we observe life processes and is on the leading edge of research discoveries into cellular and molecular mechanisms of health and disease. By incorporating the views of leading authors,this book highlights landmark discoveries and advances in mammalian cellular and microbiology research in both true spaceflight and ground-based spaceflight analogue environments for scientists and students alike who are interested in the influence of physical forces on mammalian and microbial cells, how this impactstransitionbetween normal homeostasis and disease, and basic mechanisms of adaptation to low gravity environments.To provide a thorough understanding of this research, this book covers a range of topics including:(i)description the physical forces interacting with cells in microgravity and microgravity analogue environments(ii)how alterations in these cellular forces impact human physiology, specifically immune function(iii)useof these environments to develop organotypic three-dimensional (3-D) tissue culture models as predictive human surrogates for organogenesis and disease research, and(iv)microbial pathogen responses to culture in these environments, focusing on infectious diseaseCollectively, this information reflects a critical step in preparation for long-duration human space exploration, advances our knowledge of basic biological processes and mechanisms important to understand normal function and disease, and may lead to new strategies for treatment and prevention.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 320 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume presents a broad compendium of techniques used in biodegradation and toxicological research. Through both legacy and up-to-date approaches to practical methodologies with proven results, the book examines the role and applications of analytical biodegradation quantification as it applies to the environmental sciences, particularly in the range of byproducts that are usually linked to toxicology, and the test organisms most often used in toxicity testing. Topics include scientific and technical feasibility studies, contaminant impacts evaluation, study design and analytical techniques, key methodologies required to prepare the biodegradation and toxicology protocols, as well as the handling of microbial communities related to such processes. Written for theMethods in Pharmacology and Toxicologyseries, chapters deal with a critical discussion of laboratory scale experiments, as well as full scale in situ and ex situ apparatus, with each chapter containing both a discursive section along with a detailed methods section. Detailed and authoritative,Toxicity and Biodegradation Testingis primarily focused toward the environmental sciences researcher, while the range of techniques also provides an introduction to biodegradation and toxicology methods for researchers outside of the field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 412 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before 'translational medicine' was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies.This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include:Epigenetic Variations in HypoxiaHigh Altitude AdaptationHypoxia and SleepHypoxia and the BrainMolecular Oxygen SensingPhysiological Responses to Hypoxia 788 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This case-based approach to the management of pediatric eye diseases and strabismus teaches the novice, as well as the experienced surgeon, how to conceptualize and analyze surgical planning to maximize patient outcomes, allowing readers to 'get inside the head of the surgeon.' Individual cases with clear instructions and an abundance of color illustrations, presented by experts in the field, teach critical information one case at a time. Practical Management of Pediatric Ocular Disorders and Strabismus provides the key guiding principles of a traditional textbook in an easy-to-digest format. Each chapter of the text tackles a common or rare clinical situation and begins with the description of an illustrative case. The chapters are structured with sections on case description, differential diagnosis, management and outcomes with a list of possible complications and the approach to their management. 844 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970¿s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter.But it is much more than a reference manual ¿ it is a substantial physiological and mathematical treatise in its own right.It also has a wide applicability ¿ there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the ¿black box¿ behavior of a system The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a ¿black box¿ system.Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world¿s literature on the topic and to provide in one place the wealth of important discoveries, both physiological andclinical, enabled by the technique.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This case-based approach to the management of pediatric eye diseases and strabismus teaches the novice, as well as the experienced surgeon, how to conceptualize and analyze surgical planning to maximize patient outcomes, allowing readers to ¿get inside the head of the surgeon.¿ Individual cases with clear instructions and an abundance of color illustrations, presented by experts in the field, teach critical information one case at a time.Practical Management of Pediatric Ocular Disorders and Strabismus provides the key guiding principles of a traditional textbook in an easy-to-digest format. Each chapter of the text tackles a common or rare clinical situation and begins with the description of an illustrative case. The chapters are structured with sections on case description, differential diagnosis, management and outcomes with a list of possible complications and the approach to their management.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 844 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -With a focus on anatomy and sonoantomy, this beautifully illustrated updated edition captures the latest advances in the rapidly growing field of ultrasound-guided pain medicine and MSK procedures. This atlas is divided into seven sections that provide an overview and focus on interventional approaches and advancements. Authored by international experts, each clinical chapter features a maximal number of instructive illustrations and sonograms and provides a description of sonoanatomy, instructions on performing the procedure and how to confirm appropriate needle placement. This book will help encourage and stimulate physicians to master approaches in interventional MSK and pain management.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 356 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The orchid family is one of the largest families of flowering plants known for their beauty and economic importance. This work provides information in key areas of research that are important to both scientists and commercial growers alike. The main purposes of this book are to provide key practical areas of research, such as, germination, micropropagation, traditional and current techniques related to plant improvement; document methods that ensure survival of plants from laboratories to greenhouses; promote communication between scientists and growers, so that their combined expertise on these areas will lead to the successful growth of orchids in their natural habitats or commercial greenhouses. This book can serve as reference for laymen with an interest in orchid growing.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 536 pp. Englisch.