Springer us okt 1989 (10 risultati)
Lingua: Inglese
Editore: Springer Us Okt 1989, 1989
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Buch. Condizione: Neu. Neuware - In breast cancer as in other cancers on the front line of modern interdisciplinary research we have crossed the threshhold of new understanding. Fueled by an awareness that breast cancer is a leading cause of morbidity and mortality in women and honed by rapid technological advances in molecular…mechanisms, major inroads into the darkness of this scourge have been accomplished during the past several years. Basic laboratory and clinical research findings must influence and in turn be influenced by efforts to detect, to diagnose and to cure the human disease. It is indeed gratifying to note that the efforts of scientists and clinicians from throughout the world reported in this volume are achieving this objective. The first section of the book focuses on the molecular and genetic basis of breast cancer. The role of specific oncogenes in mammary tumorigenesis using transgenic mice and mammary glands correlating molecular events with specific stages in neoplastic development are described and discussed. Such topics as the nature of specific oncogenes, levels of oncogene expression, the alteration of expression of other growth regulatory genes and the state of the cell in which the oncogene is expressed are specifically addressed. This section of the book is rounded out with discussions on the potential of genetic alterations as indicators of prognosis, the characterization of full-length cDNA codes for breast cancer markers and the function of antigens in tuomorigenesis.
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Buch. Condizione: Neu. Neuware - G. Petursson and Rikke Hoff-J0rgensen The concept of slow viral infections was first put forward in 1954 by Dr. Bjorn Sigurdsson, an Icelandic physician who had been studying some sheep diseases which were introduced into Iceland with the importation of a foreign breed of sheep in 1933. Sigurdsso…n's main criteria for defining slow infec tions were a very long initial period without clinical signs lasting months or even years following infection and a rather regular protracted, progres sive course, once clinical symptoms had appeared, usually ending in serious disease or death. Sigurdsson included in this list of slow infections maedi -visna, infectious adenomatosis of sheep, scrapie in sheep, Bittner's mam mary carcinoma and Gross' leukemia in mice. All of these diseases, except scrapie, are caused by retroviruses. The characteristics of slow infections as described above are of prac tical importance for epidemiology, diagnosis and control of these diseases. For many years the slow infections remained primarily a veterinary problem, mainly affecting sheep and goats in certain countries. In recent years, how ever, the human immunodeficiency virus (HIV) causing acquired immunodefici ency syndrome (AIDS), has suddenly appeared in many countries of the world and brought the slow infection concept forcefully to the attention of the medical profession. The disease problems and the economic effects of slow infections of sheep and goats are increasingly recognized in various coun tries. For the reasons stated above we feel that this book should be useful for veterinarians and physicians alike.
Lingua: Inglese
Editore: Springer US Okt 1989, 1989
Serie: Libro 94 di 260 - The Springer International Series in Engineering and Computer Science
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Source coding theory has as its goal the characterization of the optimal performance achievable in idealized communication systems which must code an information source for transmission over a digital communication or storage channel for…transmission to a user. The user must decode the information into a form that is a good approximation to the original. A code is optimal within some class if it achieves the best possible fidelity given whatever constraints are imposed on the code by the available channel. In theory, the primary constraint imposed on a code by the channel is its rate or resolution, the number of bits per second or per input symbol that it can transmit from sender to receiver. In the real world, complexity may be as important as rate. The origins and the basic form of much of the theory date from Shan non's classical development of noiseless source coding and source coding subject to a fidelity criterion (also called rate-distortion theory) [73] [74]. Shannon combined a probabilistic notion of information with limit theo rems from ergodic theory and a random coding technique to describe the optimal performance of systems with a constrained rate but with uncon strained complexity and delay. An alternative approach called asymptotic or high rate quantization theory based on different techniques and approx imations was introduced by Bennett at approximately the same time [4]. This approach constrained the delay but allowed the rate to grow large. 206 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In early 1986, one of us (D.M.S.) was constructing an artificial intelligence system to design algorithms, and the other (A.P.A.) was getting started in program transformations research. We shared an office, and exchanged a few papers…on the systematic development of algorithms from specifications. Gradually we realized that we were trying to solve some of the same problems. And so, despite radical differences between ourselves in research approaches, we set out together to see what we could learn from these papers. That's how this book started: a couple of graduate students trying to cope with The Literature. At first, there was just a list of papers. One of us (D.M.S.) tried to cast the papers in a uniform framework by describing the problem spaces searched, an approach used in artificial intelligence for understanding many tasks. The generalized problem space descriptions, though useful, seemed to abstract too much, so we decided to compare papers by different authors dealing with the same algorithm. These comparisons proved crucial: for then we began to see similar key design choices for each algorithm.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 132 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -No other area of biology has grown as fast and become as relevant over the last decade as virology. It is with no little amount of amaze ment, that the more we learn about fundamental biological questions and mechanisms of diseases, the more…obvious it becomes that viruses perme ate all facets of our lives. While on one hand viruses are known to cause acute and chronic, mild and fatal, focal and generalized diseases, on the other hand, they are used as tools for gaining an understanding of the structure and function of higher organisms, and as vehicles for carrying protective or curative therapies. The wide scope of approaches to different biological and medical virological questions was well rep resented by the speakers that participated in this year's Symposium. While the epidemic by the human immunodeficiency virus type 1 continues to spread without hope for much relief in sight, intriguing questions and answers in the area of diagnostics, clinical manifestations and therapeutical approaches to viral infections are unveiled daily. Let us hope, that with the increasing awareness by our society of the role played by viruses, not only as causative agents of diseases, but also as models for better understanding basic biological principles, more efforts and resources are placed into their study. Luis M. de la Maza Irvine, California Ellena M.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -No other area of biology has grown as fast and become as relevant over the last decade as virology. It is with no little amount of amaze ment, that the more we learn about fundamental biological questions and mechanisms of diseases, the m…ore obvious it becomes that viruses perme ate all facets of our lives. While on one hand viruses are known to cause acute and chronic, mild and fatal, focal and generalized diseases, on the other hand, they are used as tools for gaining an understanding of the structure and function of higher organisms, and as vehicles for carrying protective or curative therapies. The wide scope of approaches to different biological and medical virological questions was well rep resented by the speakers that participated in this year's Symposium. While the epidemic by the human immunodeficiency virus type 1 continues to spread without hope for much relief in sight, intriguing questions and answers in the area of diagnostics, clinical manifestations and therapeutical approaches to viral infections are unveiled daily. Let us hope, that with the increasing awareness by our society of the role played by viruses, not only as causative agents of diseases, but also as models for better understanding basic biological principles, more efforts and resources are placed into their study. Luis M. de la Maza Irvine, California Ellena M. 348 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fish lymphocystis disease virus (FLDV) has been tentatively classified as a separate genus of the iridovirus family. Iridoviruses were previously called icosahedral cytoplasmic deoxyriboviruses (ICDV). The Iridoviridae family contains fou…r genera including lymphocystis disease virus (proposed name Lymphocystivirus, Willis, 1989 (1'. FLDV is a causative agent of lymphocystis disease (LD) which frequently appears in Pleuronectidae (flatfish) such as Pleuronectes platessa (plaice), Platichtys flesus (flounder), Limanda limanda (dab), and Trigla gurnardus (gurnard). Fish lymphocystis disease is characterized by papilloma-like lesions, which can be induced experimentally in Lepomis macrochirus (bluegill) (2) and by subdermal injection of plaice and flounder (3). The mechanisms of this nonmalignant tumor induction are unknown. Since the discovery of LD in 1874 by Lowe (4), attempts have been made to isolate and propagate FLDV in vitro with limited success (5-7). As a first step towards understanding of the underlying mechanisms of this infectious disease the structure and properties of the causal virus must be eluciated. These basical molecular biological studies provide new facilities for investigation of virus host interactions which is necessary for understanding the molecular mechanisms of the viral pathogenesis. MATERIALS AND METHODS A total of 30 fish with LD lesions caught near the Doggerbank areas were analyzed individually, including 20 flounders, six dabs, and four plaice. Virions of FLDV from LD lesions of each species of fish were isolated, purified, and examined by electron microscopy as 205 described previously (8). Fig. 324 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Fish lymphocystis disease virus (FLDV) has been tentatively classified as a separate genus of the iridovirus family. Iridoviruses were previously called icosahedral cytoplasmic deoxyriboviruses (ICDV). The Iridoviridae family contains four ge…nera including lymphocystis disease virus (proposed name Lymphocystivirus, Willis, 1989 (1». FLDV is a causative agent of lymphocystis disease (LD) which frequently appears in Pleuronectidae (flatfish) such as Pleuronectes platessa (plaice), Platichtys flesus (flounder), Limanda limanda (dab), and Trigla gurnardus (gurnard). Fish lymphocystis disease is characterized by papilloma-like lesions, which can be induced experimentally in Lepomis macrochirus (bluegill) (2) and by subdermal injection of plaice and flounder (3). The mechanisms of this nonmalignant tumor induction are unknown. Since the discovery of LD in 1874 by Lowe (4), attempts have been made to isolate and propagate FLDV in vitro with limited success (5-7). As a first step towards understanding of the underlying mechanisms of this infectious disease the structure and properties of the causal virus must be eluciated. These basical molecular biological studies provide new facilities for investigation of virus host interactions which is necessary for understanding the molecular mechanisms of the viral pathogenesis. MATERIALS AND METHODS A total of 30 fish with LD lesions caught near the Doggerbank areas were analyzed individually, including 20 flounders, six dabs, and four plaice. Virions of FLDV from LD lesions of each species of fish were isolated, purified, and examined by electron microscopy as 205 described previously (8). Fig.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 324 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume comprises the proceedings of the sixth in a series of International Symposia devoted to basic and clinical aspects of urolithiasis. Previous symposia have been held at intervals of four years in Leeds, Madrid, Davos, Williamsb…urg, and Garmisch-Partenkirchen. The sixth symposium was held in Vancouver, British Columbia and was attended by over 250 participants from 26 countries around the world. As may be seen from the contents of this volume, the meeting covered many aspects of urolithiasis including the underlying physiology, crystal formation and the effects of inhibitors and promoters on crystallization, endocrinology and abnormalities of urinary composition, analyses, geography and epidemiology, and medical and surgical treatment with a special emphasis on extracorporeal lithotripsy. Internationally-recognized authorities gave invited talks in each of these areas, and from the submitted abstracts 30 were selected for oral presentation and the remainder were presented in either general or theme poster sessions. The nine theme-poster sessions provided a particularly valuable and successful feature of the meeting, giving an opportunity for a group of researchers working in related areas to present their posters and also to give a brief oral summary which was followed by discussion with the audience. Each of these poster sessions was chaired by two experts in the field who have provided an overview of each theme-poster session for this volume. 1108 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume comprises the proceedings of the sixth in a series of International Symposia devoted to basic and clinical aspects of urolithiasis. Previous symposia have been held at intervals of four years in Leeds, Madrid, Davos, Williamsburg,… and Garmisch-Partenkirchen. The sixth symposium was held in Vancouver, British Columbia and was attended by over 250 participants from 26 countries around the world. As may be seen from the contents of this volume, the meeting covered many aspects of urolithiasis including the underlying physiology, crystal formation and the effects of inhibitors and promoters on crystallization, endocrinology and abnormalities of urinary composition, analyses, geography and epidemiology, and medical and surgical treatment with a special emphasis on extracorporeal lithotripsy. Internationally-recognized authorities gave invited talks in each of these areas, and from the submitted abstracts 30 were selected for oral presentation and the remainder were presented in either general or theme poster sessions. The nine theme-poster sessions provided a particularly valuable and successful feature of the meeting, giving an opportunity for a group of researchers working in related areas to present their posters and also to give a brief oral summary which was followed by discussion with the audience. Each of these poster sessions was chaired by two experts in the field who have provided an overview of each theme-poster session for this volume. 1108 pp. Englisch.
