springer us okt 2017 (19 risultati)

Taschenbuch. Condizione: Neu. Neuware -This concise and practical resource brings together recent advances in identifying and managing anemia of chronic disease (inflammation), genetically related anemia and anemia related to chronic end organ damage. Chapters provide a detailed analysis of the current science of anemia, approaches to different patient populations, comorbid conditions and nutritional aspects of anemia. Novel therapies focused on physiological pathways are introduced and discussed. Controversies from the perspective of subspecialists focused in treating major causes of anemia within their specific disciplines are also presented. Easy-to-reference and authored by experts in each clinical scenario, Management of Anemia is the launching point for learning more about this challenging and common condition.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The new edition of this volume features a concise yet comprehensive review of sepsis. In addition to thoroughly revised chapters from the previous edition that covers the latest in diagnostics, therapeutics, and antimicrobials, the third edition features new chapters on the economic impact of infections and antibiotics, multi-organ failure in sepsis, and current strategies for training high-performance teams.Written by an international group of experts in the field, Sepsis, Third Edition is a valuable resource that provides the most practical information for clinicians and practitioners who treat this complication in the ICU.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This Second Edition of the book expands on the in-depth treatment of the theory, definition, and evaluation of impairment presented in the original volume. It explores the complex relationships between disabling conditions and impairment, with new data and insights on assessment and potential avenues for treatment. Original and revised chapters critique current models of impairment and offers an integrated model rooted in the contexts of medical, mental health, and cognitive challenges in disability. Leading scholars and clinicians provide updated evidence for a much-needed reconceptualization of impairment within the context of diagnosis and disability. This contextual approach to assessment ¿ a wide-ranging quality-of life perspective ¿ goes beyond symptom counting, resulting in more accurate diagnosis, targeted interventions, and improved patient functioning.Topics featured in this book include:The role of family and cross-setting supports inreducing impairment.Relationships between adaptive behavior and impairment.Legal conceptions of impairment and its implications for the assessment of psychiatric disabilities.Impairment in parenting.The Neuropsychological Impairment Scale (NIS).The Barkley Functional Impairment Scale (BFIS).The Rating Scale of Impairment (RSI).Treatment integrity in interventions for children diagnosed with DSM-5 disorders.Assessing Impairment, Second Edition, is a must-have resource for researchers, clinicians, professionals, and graduate students in clinical child, school, and developmental psychology as well as child and adolescent psychiatry, educational psychology, rehabilitation medicine/therapy, social work, and pediatrics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume provides readers with the latest techniques and approaches used to study K+ channels. There are a wide range of topics covered in the book, such as channel structure; K+ channels and their roles in physiology and disease; single-molecule FRET; proteins expression levels in vivo; real-time correlation of channel activity; gating; pharmacology; physiological functions; and channelopathies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Potassium Channels: Methods and Protocols is a valuable resource for all researchers who are interested in studying potassium channels.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume presents protocols forBrachypodiumgenomics in numerous areas ranging from marker development, trait evolution, functional genomics, metabolomics, transcriptomics, genomics, and tilling. This book also explores techniques to study the widening genetic base ofBrachypodiumthat will help researchers better understand the model plant using NGS technologies. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive,Brachypodium Genomics: Methods and Protocolsis a valuable resource for bench-oriented molecular biologists and computational biologists working towards further evolving this field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Buch. Condizione: Neu. Neuware -The aim of this volume is to make computer programs for analyzing human genetic data more easily accessible to the beginner.Statistical Human Genetics: Methods and Protocols, Second Editionprovides updated and new chapters detailing genetic terms, analysis software, and how to interpret the program outputs. Written in the highly successfulMethods in Molecular Biologyseries format, the chaptersinclude introductions to their respective topics, step-by-stepinstructions,and tips on troubleshooting and avoiding known pitfalls.The purpose ofStatistical Human Genetics: Methods and Protocols, Second Editionis to ensure successful and meaningful results in the fast-growing field of genetic epidemiology.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 704 pp. Englisch.

Buch. Condizione: Neu. Neuware -This important volume brings together significant findings on the neural bases of spoken language ¿its processing, use, and organization, including its phylogenetic roots. Employing a potent mix of conceptual and neuroimaging-based approaches, contributors delve deeply into specialized structures of the speech system, locating sensory and cognitive mechanisms involved in listening and comprehension, grasping meanings and storing memories. The novel perspectives revise familiar models by tracing linguistic interactions within and between neural systems, homing in on the brain¿s semantic network, exploring the neuroscience behind bilingualism and multilingual fluency, and even making a compelling case for a more nuanced participation of the motor system in speech. From these advances, readers have a more three-dimensional picture of the brain¿its functional epicenters, its connections, and the whole¿as the seat of language in both wellness and disorders.Included in the topics: The interaction between storage and computation in morphosyntactic processing. The role of language in structure-dependent cognition. Multisensory integration in speech processing: neural mechanisms of cross-modalafter-effect. A neurocognitive view of the bilingual brain. Causal modeling: methods and their application to speech and language. A word in the hand: the gestural origins of language.Neural Mechanisms of Languagepresents a sophisticated mix of detail and creative approaches to understanding brain structure and function, giving neuropsychologists, cognitive neuroscientists, developmental psychologists, cognitive psychologists, and speech/language pathologists new windows onto the research shaping their respective fields.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This ambitious volume brings together and assesses all major systematic reviews of the effectiveness of criminological interventions, to draw broad conclusions about what works in policing, corrections, developmental prevention, situational prevention, drug abuse treatments, sentencing and deterrence, and communities.Systematic reviews aim to minimize any possible bias in drawing conclusions by stating explicit criteria for inclusion and exclusion of studies, by conducting extensive and wide-ranging searches for possibly eligible studies, and by making all stages of the review explicit and transparent so that the methods can be checked and replicated. Over a decade ago, a concerted effort was made by members of the criminology community, including the Editors and contributors of this volume, to bring the practice of systematic reviews to the study of Criminology, providing replicable, evidence-based data to answer key questions about the study of crime causation, detection, and prevention. Now, the pioneers in this effort present a comprehensive stock-taking of what has been learned in the past decade of systematic reviews in criminology. Much has been discovered about the effectiveness of (for example) boot camps, ¿hot spots¿ policing, closed-circuit television surveillance, neighborhood watch, anti-bullying programs in schools, early parenting programs, drug treatment programs, and other key topics.This volume will be of interest to researchers in criminology and criminal justice, as well as in related fields such as public health and forensic science, with important implications for policy-makers and practitioners.Decisively showing that the ¿nothing works¿ era is over, this volume takes stock of what we know, and still need to know, to prevent crime. I plan to keep this book close at hand and to use it often!Francis T. Cullen, Distinguished Research Professor Emeritus, University of Cincinnati At a time when there is a broad commitment to bringing science to the front lines of practice, this book should be on the reading list of both policymakers and scholars.Laurie O. Robinson, Clarence J. Robinson Professor of Criminology, Law Society, George Mason University and former Assistant Attorney General of the U.S. Department of JusticeSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 352 pp. Englisch.

Buch. Condizione: Neu. Neuware Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 364 pp. Englisch.

Buch. Condizione: Neu. Neuware -This second edition details some of the recent trends in HCS/HCA/HCI. New and updated chapters guide readers through methods that utilize reagents and kits that have been developed to measure cells and subpopulation classifications, control measures, overviews of the data handling issues associated with HCS/HCA/HCI, and methods to implement more complex phenotypic models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, High Content Screening and Analysis-The Ideal Format for Phenotypic Screening: A Powerful Approach to Systems Cell Biology and Drug Discovery, Second Edition aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 416 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume explores the latest techniques used by researchers to help them better understand the NMDAR structure-function relations, principles, and rules that govern how NMDARs operate in brain processing. The volume includes a detailed introductory chapter describing the field and is divided into three parts. Topics covered in the volume include: quantification of NMDAR subunit genes expression by qRT-PCR; detection of NMDARs antibodies in encephalitis; recombinant channels in host cells using a fast agonist application system; GluNs detection and functions in microglial cells; and NMDARs as voltage sensors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, NMDA Receptors: Methods and Protocols is a valuable resource that discusses the diversity of the currently-used methods, the importance of NMDARs and their complexity, and the progress that has already been made. This book will be of interest to scientists, clinicians, and industry professionals working in this field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume discusses techniques used for the molecular characterization of maize. This book is divided into 4 parts: cell, tissue, and organ culture and maize transformation; gene silencing and generation of mutant populations; plant gene expression; and plant metabolic networks. The chapters cover a range of topics, such as growing and propagating maize in the laboratory, greenhouse and field studies, screening mutagenic population, characterizing the genome, describing protein and metabolic regulatory networks, and generating transgenic plants for gene knock-out and over expression purposes. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive,Maize: Methods and Protocolsis a valuable resource for everyone who is interested in maize research.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 248 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume provides a comprehensive study of this key method of gel-based proteomics. Chapters in Difference Gel Electrophoresis: Methods and Protocols detail methods on principles of differential protein labeling, two-dimensional gel electrophoresis, techniques on optimized proteomic workflows, advanced mass spectrometry for protein identification, application of basic biological research, and applied biomarker discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Difference Gel Electrophoresis: Methods and Protocols aims to ensure successful results in the further study of this vital field.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 328 pp. Englisch.

Buch. Condizione: Neu. Neuware -Reflecting developments in genome editing, this third edition volume fully updates a collection of key techniques for the study of functional genomics. The book is broken up into sections on bioinformatics, DNA, RNA, and protein analysis, as well as a closing section entitled ¿From Genotype to Phenotype.¿ Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Updated and authoritative,Functional Genomics: Methods and Protocols, Third Editionseeks to aid scientists in establishing or extending technologies and techniques in their laboratories.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 408 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume presents protocols that analyze and explore hemorrhagic fever viruses (HFV). This book is divided into 5 parts: Part I begins with an overview on predicting viral pandemics and then covers methods for surveillance, diagnosis, and classification of HFV. This includes an antibody capture method using Lassa virus antigens. Part II discusses structural studies and reverse genetics of HFV. The chapters in this part describe envelope glycoprotein membrane fusion studies, arenavirus nucleocapsid protein, and the use of virus-like-particles to study viral egress. Part III explores in vivo models of HFV infections, and contains chapters on murine, guinea pig, and primate models for HFV, and methods to obtain a subset of primary human liver cells that can be cultured long-term. Part IV looks into immune assays and vaccine production for HFV. The chapters in this section cover the attenuated vaccine for Argentine HFV, detecting virus-antibody immune complexes in secondary dengue infections, and DNA vaccination. Part V discusses host responses to viral hemorrhagic fever, and contains chapters on identifying host restrictions to Junín or Dengue infection, and a cell-culture method to assess coagulation after HFV infection. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Hemorrhagic Fever Viruses: Methods and Protocols is a valuable resource for scientists and researchers who want to bridge the gap between virus recognition in surveillance and understanding host responses to infection.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 444 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume provides readers with a collection of the latest protocols used by researchers to study polyamines (PA). The chapters in this book cover various topics, such as quantification of different polyamines and conjugates, subcellular localization studies, transport, DNA methylation, ODC regulation, genetic and phenotyping analyses, genome-wide association mapping, polyamine applications and cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, Polyamines: Methods and Protocols is a useful reference for researchers looking to advance and stimulate their knowledge of polyamines.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 532 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This Second Edition of the book expands on the in-depth treatment of the theory, definition, and evaluation of impairment presented in the original volume. It explores the complex relationships between disabling conditions and impairment, with new data and insights on assessment and potential avenues for treatment. Original and revised chapters critique current models of impairment and offers an integrated model rooted in the contexts of medical, mental health, and cognitive challenges in disability. Leading scholars and clinicians provide updated evidence for a much-needed reconceptualization of impairment within the context of diagnosis and disability. This contextual approach to assessment - a wide-ranging quality-of life perspective - goes beyond symptom counting, resulting in more accurate diagnosis, targeted interventions, and improved patient functioning.Topics featured in this book include:The role of family and cross-setting supports in reducing impairment.Relationships between adaptive behavior and impairment.Legal conceptions of impairment and its implications for the assessment of psychiatric disabilities.Impairment in parenting.The Neuropsychological Impairment Scale (NIS).The Barkley Functional Impairment Scale (BFIS).The Rating Scale of Impairment (RSI).Treatment integrity in interventions for children diagnosed with DSM-5 disorders.Assessing Impairment, Second Edition, is a must-have resource for researchers, clinicians, professionals, and graduate students in clinical child, school, and developmental psychology as well as child and adolescent psychiatry, educational psychology, rehabilitation medicine/therapy, social work, and pediatrics. 348 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This important volume brings together significant findings on the neural bases of spoken language -its processing, use, and organization, including its phylogenetic roots. Employing a potent mix of conceptual and neuroimaging-based approaches, contributors delve deeply into specialized structures of the speech system, locating sensory and cognitive mechanisms involved in listening and comprehension, grasping meanings and storing memories. The novel perspectives revise familiar models by tracing linguistic interactions within and between neural systems, homing in on the brain's semantic network, exploring the neuroscience behind bilingualism and multilingual fluency, and even making a compelling case for a more nuanced participation of the motor system in speech. From these advances, readers have a more three-dimensional picture of the brain-its functional epicenters, its connections, and the whole-as the seat of language in both wellness and disorders.Included in the topics: The interaction between storage and computation in morphosyntactic processing. The role of language in structure-dependent cognition. Multisensory integration in speech processing: neural mechanisms of cross-modal after-effect. A neurocognitive view of the bilingual brain. Causal modeling: methods and their application to speech and language. A word in the hand: the gestural origins of language. Neural Mechanisms of Language presents a sophisticated mix of detail and creative approaches to understanding brain structure and function, giving neuropsychologists, cognitive neuroscientists, developmental psychologists, cognitive psychologists, and speech/language pathologists new windows onto the research shaping their respective fields. 236 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume explores the latest techniques used by researchers to help them better understand the NMDAR structure-function relations, principles, and rules that govern how NMDARs operate in brain processing. The volume includes a detailed introductory chapter describing the field and is divided into three parts. Topics covered in the volume include: quantification of NMDAR subunit genes expression by qRT-PCR; detection of NMDARs antibodies in encephalitis; recombinant channels in host cells using a fast agonist application system; GluNs detection and functions in microglial cells; and NMDARs as voltage sensors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and practical, NMDA Receptors: Methods and Protocols is a valuable resource that discusses the diversity of the currently-used methods, the importance of NMDARs and their complexity, and the progress that has already been made. This book will be of interest to scientists, clinicians, and industry professionals working in this field. 328 pp. Englisch.