springer us sep 2007 (56 risultati)

Taschenbuch. Condizione: Neu. Neuware -Can you remember being impressed by a clear starry sky Look at the Milky Way through binoculars and it will reveal its many hundreds of thousands of stars, double stars, stellar clusters, and nebulae. If you are a new observer, it is not that easy to nd your way in this swarm of stars, but this atlas tries to make it as easy as possible. So now it is not just experienced amateurs that can enjoy looking at the heavens. Two additional observing aids are recommended. The rst is a planisphere, where one can dial in the time and day in order to see which constellations are visible and where they are in the sky. The second is an astronomical yearbook listing the current positions of the planets and all important phenomena. So, let us begin our journey around the night sky, and see what the universe can reveal to us! Sky Atlases Most sky atlases can be classi ed into one of two major groups according to the number of stars they contain. Some atlases only show the stars visible to the nakedeye. As there are not more than a few thousand such stars, such charts can be simple and clear and can be arranged in a handy format. They are ideal for all naked-eye Facing page, top: The constellation Cygnus (Swan) in the midst of the northern Milky Way.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 172 pp. Englisch.

Buch. Condizione: Neu. Neuware -Performance evaluation of increasingly complex human-made systems requires the use of simulation models. However, these systems are difficult to describe and capture by succinct mathematical models. Accepting the need for search-based methods as a complement to established analytical techniques, quickly narrowing the search for optimum performance (ordinal optimization) is more important than accurately estimating the values of system performance during the process of optimization (cardinal optimization).The purpose of this book is to address the difficulties of the optimization of complex systems via simulation models or other computation-intensive models involving possible stochastic effects and discrete choices. This book will establish distinct advantages of the 'softer' ordinal approach for search-based type problems, analyze its general properties, and show the many orders of magnitude improvement in computational efficiency that is possible.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Risk analysis and risk assessment have been with us long enough for the terms to sound familiar to most people. Standard fare for the nuclear power industry and the military for a half a century or more, risk assessment is now a routine aspect of environmental management, public health and individual medical decision making. There have been popular books on risk, and the current poker craze will likely spread risk concepts to an even wider (and younger) audience. Yet, despite all of this extensive and varied experience, we the analysts and practitioners have not done nearly enough to explain to the people who need to know what they need to know ¿ especially the uncertainty inherent in risk estimates. There are many instances in which the failure to communicate risk information accurately or completely has had an important and material impact on decisions and actions. I have been involved in some of these, ranging from local plans for water management to national decisions about nuclear waste. I have seen first hand the effects of poorly done risk asse- ments and bad risk communication, and especially the way in which the uncertainly of risk estimates is handled (or mishandled). The con- quences of doing this wrong are high. It¿s high time that we addressed this gap in understanding, and this book is an excellent and important step in doing so.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.

Buch. Condizione: Neu. Neuware -Nearly everything making up what we call the ¿environment¿ of a plant has an infuence on the way it grows. Sunlight, te- perature, moisture contents of soil and atmosphere and vib- tions are all obvious examples of environmental components, and transient variations in their amount or intensity lead the plant to manifest more or less immediate responses. Small changes in carbon dioxide level in the atmosphere can even have effects, but these take a longer time to be registered ¿ at least those that are visible, albeit at the microscopic level. Plants meet the challenges of the environment by means of acclimation. In this respect, plants are notable for the pl- ticity of their development. However, where morphological or physiological plasticity is no longer an option, the responses would be by means of adaptations as a result of genetic - lection or genetic ¿assimilation¿ (Waddington 1957). Thus, a feature that was once a facultative transient response to an environmental perturbation becomes a constitutive charac- ristic of plant structure or function. It is in this way that the environment continually molds the way in which plants de- lop, and also defnes the areas upon planet Earth where they will thrive.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 144 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware - Since its original appearance in 1977, Advanced Organic Chemistry has maintained its place as the premier textbook in the field, offering broad coverage of the structure, reactivity and synthesis of organic compounds. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed. The two-part fifth edition has been substantially revised and reorganized for greater clarity. Among the changes: Updated material reflecting advances in the field since 2001's Fourth Edition, especially in computational chemistry; A companion Web site provides digital models for study of structure, reaction and selectivity; Solutions to the exercises provided to instructors online. The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. Together with Part A: Structure and Mechanisms, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry.

Buch. Condizione: Neu. Neuware -Dynamic Fleet Management will focus on real time management of a distribution system. This means that when a dynamic event occurs within the distribution chain, action must be taken in 'real-time.' The book will integrate the latest results in system design, algorithm development and system implementation, to capture the state-of-the art research and application trends. While much of the research in this area of transportation problems have almost exclusively concentrated on carrying out static plans on optional distribution conditions, this book will examine those problems when some dynamic or unplanned even occurs within the transport or network system. It will focus specifically on these cases and integrate the latest results in systems, routing algorithms and case studies where information (a dynamic event) is revealed to the decision maker in a real-time manner.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Buch. Condizione: Neu. Neuware -Anemia in the elderly has been properly defined as the silent epidemic, representing 3 million people in the United States aged 65 years and older. Incidence and prevalence of this condition increase with age. It differs in its etiology, pathogenesis and treatment from anemia in children and younger adults. Anemia is associated with reduced survival, increased risk of functional dependence and hospitalization, increased risk of congestive heart failure and stage renal disease and cognitive disorders. Approximately 70% of anemia in older individuals is reversible.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 156 pp. Englisch.

Buch. Condizione: Neu. Neuware -Science is like a tree: contrary to popular belief, both trees and science grow at their edges, not at their core. For science, this means that most of the fruitful and exciting developments are not happening at the core of established elds, but are instead happening at the boundaries between such elds. This has been particularly true for Computer Science. The most interesting database developments don¿t happen inside the Database community, but rather where databases hit Biology. Similarly, the most interesting developments in Ar- cial Intelligence in recent years have happened where AI met the Web. Theyoung eldofSemanticWebresearchhasbeenoneoftheresultsofanumber of different sub elds of Computer Science being exposed to the challenges of the Web: databases, computational linguistics, knowledge representation, knowled- based systems and service-oriented computing are just some of the sub elds that are all making contributions to the Semantic Web vision, namely a Web that consists not only of linksbetween web-pagesfull of picturesand text, but of a Semantic Web that consists of links between computer-interpretable data. Such a Semantic Web would make it possible to query and reason over integrated data-sets consisting of separate pieces of information that were never intended to be linked together, but that can nevertheless be fruitfully combined and integrated, sometimes even by a third party who neither wrote nor ownsany of the original piecesof data (just as is possible with web-pages on the current Web).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

Buch. Condizione: Neu. Neuware -Resilience is an increasingly important concept and quality in today¿s world. It is particularly important in the area of Critical Infrastructures. It is crucial in the area of Critical Information Infrastructure. This is because, since the year 2000, man has been dependent on information and telecommunications systems for survival, particularly in the Organization for Economic Cooperation and Development (OECD) countries, and because all other Critical Inf- structures depend upon, to a greater or lesser extent, Critical Information 1,2 Infrastructure. Until, probably, the late 1980s it would be fair to say that the defense of individual nation states depended upon a mixture of political will and armed might. The fall of the Berlin Wall may have effectively ended the Cold War, and with it a bipolar world, but it brought globalization and a multipolar digital world in its wake. Simply put, a number of power vacuums were created and these have yet to be fully filled and settled. In this ¿New World¿ many changes were afoot. These changes include the increasing irrelevance of nation states in federated structures and the export of democracy on the back of globalization. One of the biggest changes, though, is the use of digital technolo gy by the OECD countries. This is on such a scale that these countries have become both dependent upon information technology and as individual 3 states largely irrelevant to the new ¿global¿ electronic economy. 1 This adaptation of Maslow¿s hierarchy of needs is attributed to KPMG.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book explores the role of surface effects in optical phenomena in nanoscience, from two different perspectives. When systems are reduced in volume, the ratio of surface versus volume increases. At the level of single nanostructures this translates into an enhanced role of interfacial chemistry and thermodynamics. At the level of systems of nanostructures, it translates into larger density on interfaces, which in turn leads to such intriguing collective effects as plasmonics or multiple reflection and refraction phenomena. The book highlights both perspectives presenting sample applications. Without claiming to be exhaustive, the book aims to stimulate readers in this potentially rewarding field.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Buch. Condizione: Neu. Neuware -In the United States, 20.8 million children and adults, 7% of the population, have diabetes. While an estimated 14.6 million have been diagnosed, 6.2 million have yet to be diagnosed. Worldwide diabetes afflicts 150 million people. The World Health Organization estimates that by 2025 that figure will double. Diabetes is responsible for more deaths than AIDS and breast cancer, combined. It is a leading cause of blindness, kidney failure, amputations, heart complications and stroke.Treatment of Type 1 and Type diabetes has changed radically over the past few years. There are new opportunities for treating the key abnormality in diabetes, increased blood glucose, by effective agents such as new insulin preparations and oral agents.Increasing so-called non-glycemic intervention is of prime importance. Blood pressure lowering therapies, anti-cholesterol strategies, and specific treatment related to complications is becoming increasingly important.Pharmacotherapy of Diabetes is a unique, invaluable guide to all aspects of the pharmacological treatment of diabetes, covering basic concepts and an in-depth review of current and future therapies. This work provides an overview for the new changes in therapies that can be implemented in clinical practice and treatment of the diabetic patient.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Buch. Condizione: Neu. Neuware -Adaptive Nonlinear System Identification: The Volterra and Wiener Model Approaches introduces engineers and researchers to the field of nonlinear adaptive system identification. The book includes recent research results in the area of adaptive nonlinear system identification and presents simple, concise, easy-to-understand methods for identifying nonlinear systems. These methods use adaptive filter algorithms that are well known for linear systems identification. They are applicable for nonlinear systems that can be efficiently modeled by polynomials.After a brief introduction to nonlinear systems and to adaptive system identification, the author presents the discrete Volterra model approach. This is followed by an explanation of the Wiener model approach. Adaptive algorithms using both models are developed. The performance of the two methods are then compared to determine which model performs better for system identification applications.Adaptive Nonlinear System Identification: The Volterra and Wiener Model Approaches is useful to graduates students, engineers and researchers in the areas of nonlinear systems, control, biomedical systems and in adaptive signal processing.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 248 pp. Englisch.

Buch. Condizione: Neu. Neuware -This volume presents the proceedings of the IFIP TC2 WG 2.5 Conference on Grid-Based Problem Solving Environments: Implications for Development and Deployment of Numerical Software, held in Prescott, Arizona from July 17-21, 2006. The book contains the most up-to-date research on grid-based computing. It will interest users and developers of both grid-based and traditional problem solving environments, developers of grid infrastructure, and developers of numerical software.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 480 pp. Englisch.

Buch. Condizione: Neu. Neuware -¿If you torture the data long enough, Nature will confess,¿ said 1991 Nobel-winning economist Ronald Coase. The statement is still true. However, achieving this lofty goal is not easy. First, ¿long enough¿ may, in practice, be ¿too long¿ in many applications and thus unacceptable. Second, to get ¿confession¿ from large data sets one needs to use state-of-the-art ¿torturing¿ tools. Third, Nature is very stubborn ¿ not yielding easily or unwilling to reveal its secrets at all. Fortunately, while being aware of the above facts, the reader (a data miner) will find several efficient data mining tools described in this excellent book. The book discusses various issues connecting the whole spectrum of approaches, methods, techniques and algorithms falling under the umbrella of data mining. It starts with data understanding and preprocessing, then goes through a set of methods for supervised and unsupervised learning, and concludes with model assessment, data security and privacy issues. It is this specific approach of using the knowledge discovery process that makes this book a rare one indeed, and thus an indispensable addition to many other books on data mining. To be more precise, this is a book on knowledge discovery from data. As for the data sets, the easy-to-make statement is that there is no part of modern human activity left untouched by both the need and the desire to collect data. The consequence of such a state of affairs is obvious.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 624 pp. Englisch.

Buch. Condizione: Neu. Neuware -Comprehensive in scope and meticulously researched, Handbook of Obesity Prevention analyzes the intricate causes of this public health crisis, and sets out concrete, multilevel strategies for meeting it head-on. This innovative handbook starts by clearly defining obesity in clinical, epidemiologic, and financial terms. From there, expert contributors provide insights on current issues, methods, and controversies in the field, focusing on new opportunities for prevention, successful interventions and initiatives, and guidelines for planning and implementing programs and evaluating results. This systematic approach to large-scale social and policy change gives all parties involved - from individual practitioners to multinational corporations - the tools to set and attain realistic goals based on solid evidence and best practice in public health.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 564 pp. Englisch.

Buch. Condizione: Neu. Neuware -Solving multi-objective problems is an evolving effort, and computer science and other related disciplines have given rise to many powerful deterministic and stochastic techniques for addressing these large-dimensional optimization problems. Evolutionary algorithms are one such generic stochastic approach that has proven to be successful and widely applicable in solving both single-objective and multi-objective problems.This textbook is a second edition of Evolutionary Algorithms for Solving Multi-Objective Problems, significantly expanded and adapted for the classroom. The various features of multi-objective evolutionary algorithms are presented here in an innovative and student-friendly fashion, incorporating state-of-the-art research. The book disseminates the application of evolutionary algorithm techniques to a variety of practical problems, including test suites with associated performance based on a variety of appropriate metrics, as well as serial and parallel algorithm implementations.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 824 pp. Englisch.

Buch. Condizione: Neu. Neuware -Handbook of Operations Research in Natural Resources will be the first systematic handbook treatment of quantitative modeling natural resource problems, their allocated efficient use, and societal and economic impact. Andrés Weintraub is the very top person in Natural Resource research. Moreover, he has an international reputation in OR and a former president of the International Federation of Operational Research Societies (IFORS). He has selected co-editors who are at the top of the sub-fields in natural resources: agriculture, fisheries, forestry, and mining. The book will cover these areas in terms with contributions from researchers on modeling natural research problems, quantifying data, developing algorithms, and discussing the benefits of research implementations. The handbook will include tutorial contributions when necessary. Throughout the book, technological advances and algorithmic developments that have been driven by natural resource problems will be called out and discussed.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 636 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book carefully details design tools and techniques for realizing low power and energy efficiency in a highly productive design methodology.Important topics include: Microarchitectural techniques to reduce energy per operation Power reduction with timing slack from pipelining Analysis of the benefits of using multiple supply and threshold voltages Placement techniques for multiple supply voltages Verification for multiple voltage domains Improved algorithms for gate sizing, and assignment of supply and threshold voltages Power gating design automation to reduce leakage Relationships among tatistical timing, power analysis, and parametric yield optimizationDesign examples illustrate that these techniques can improve energy efficiency by two to three times.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 400 pp. Englisch.

Buch. Condizione: Neu. Neuware -In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Breast Cancer Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. Breast Cancer Chemosensitivity provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Buch. Condizione: Neu. Neuware -Modern Circuit Placement: Best Practices and Results describes advanced techniques in VLSI circuit placement which is one of the most important steps of the VLSI physical design flow. Physical design addresses the back-end layout stage of the chip design process. As technology scales down, the significance of interconnect optimization becomes much more important and physical design, particularly the placement process, is essential to interconnect optimization.This book has four unique characteristics. First, it focuses on the most recent highly scalable placement techniques used for multi-million gate circuit designs, with consideration of many practical aspects of modern circuit placement, such as density and routability control, mixed-size placement support, and area I/O support. Second the book addresses dominant techniques being used in the field. This book includes all the academic placement tools that competed at the International Symposium on Physical Design (ISPD) placement contest in 2005 and 2006. Although these tools are developed by academia, many core techniques in these tools are being used extensively in industry and represent today¿s advanced placement techniques. Third, the book provides quantitative comparison among the various techniques on common benchmark circuits derived from real-life industrial designs. The book includes significant amounts of analysis on each technique, such as trade-offs between quality-of-results (QoR) and runtime. Finally, analysis of the optimality of the placement techniques is included. This is done by utilizing placement benchmarks with known optimal solutions, yet with characteristics similar to real industrial designs.Modern Circuit Placement: Best Practices and Results is a valuable tool and a must-read for graduate students, researchers and CAD tool developers in the VLSI physical synthesis and physical design fields.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 344 pp. Englisch.

Buch. Condizione: Neu. Neuware -In 1971, I started a fellowship in infectious diseases and medical microbiology at the Channing Laboratory of the Harvard Medical Service at Boston City Hospital. My mentor, Dr. Maxwell Finland, had encouraged me to return there from the Center for Disease Control (as CDC was known then), where I had studied inf- tious diseases epidemiology and hospital-associated infection epidemiology, with the idea that we would review the demographic patterns of bacteremia and several other infections during Dr. Finland¿s long tenure at the hospital. We did so, but I was surprised to find that he also invited me to help with the assessment of the success or failure of the programs to control antimicrobial use that he and c- leagues had put into place at the hospital over several years. The paper describing that review finally was published in 1974, after a long and tortuous process of review at several journals. Several reviewers felt that such attempts to improve use amounted to interference with the patient¿s physician to do what was best. Others felt that such programs focused incorrectly on a subject other than treating the current patient. Fortunately, today, it is clear that antimicrobial resistance results in major part, but not entirely, from the ways that we use antimicrobial agents, and that the ov- all interests of patients in general, as well as those of society, are well served by efforts to use these drugs as well as possible.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Over the past twenty-five years, the effects of the spatial distribution and scaling of resources on animal populations have been increasingly studied in wildlife biology, landscape ecology, conservation biology, and related fields. However, spatial patterns change over time. In Temporal Dimensions of Landscape Ecology: Wildlife Responses to Variable Resources, the authors discuss the effects that temporal changes in resources have on animal populations. Resource availability and quality are not distributed homogeneously over time, depending for example on predictable changes in seasons, mating and birthing cycles, unpredictable resource pulses and weather-related phenomena, ecological disturbances, and historical legacies.Temporal Dimensions of Landscape Ecology brings together chapters that address the idea of current as well as historical temporal influences on resource availability, quality, and distribution. The authors draw attention to the neglected temporal issues so important to understanding species and community responses. This book will be of interest to both wildlife and conservation students and practitioners working with temporal and spatial scale issues.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Market demand for microprocessor performance has motivated continued scaling of CMOS through a succession of lithography generations. Quantum mechanical limitations to continued scaling are becoming readily apparent. Partially Depleted Silicon-on-Insulator (PD-SOI) technology is emerging as a promising means of addressing these limitations. It also introduces additional design complexity which must be well understood.SOI Circuit Design Concepts first introduces the student or practicing engineer to SOI device physics and its fundamental idiosyncrasies. It then walks the reader through realizations of these mechanisms which are observed in common high-speed microprocessor designs. Rules of thumb and comparisons to conventional bulk CMOS are offered to guide implementation. SOI's ultimate advantage, however, may lie in the unique circuit topologies it supports; a number of these novel new approaches are described as well.SOI Circuit Design Concepts draws upon the latest industry literature as well as the firsthand experiences of its authors. It is an ideal introduction to the concepts of governing SOI use and provides a firm foundation for further study of this exciting new technology paradigm.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Buch. Condizione: Neu. Neuware -No books have been published on the practice of neuroscience in the eighteenth century, a time of transition and discovery in science and medicine. This volume explores neuroscience and reviews developments in anatomy, physiology, and medicine in the era some call the Age of Reason, and others the Enlightenment. Topics include how neuroscience adopted electricity as the nerve force, how disorders such as aphasia and hysteria were treated, Mesmerism, and more.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book provides an integrated, technical exposition of key concepts in agency theory, with particular emphasis on analyses of the economic consequences of the characteristics of contractible performance measures, such as accounting reports. It is not a survey of the literature, but provides a succinct source for learning the fundamentals of the economics of incentives. While there is an emphasis on information issues of interest to accounting researchers, it is also relevant to researchers in economics, finance, management science, and other disciplines who are interested in the economics of management incentives.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 688 pp. Englisch.

Buch. Condizione: Neu. Neuware - Entrepreneurship is among the most vibrant and important parts of the economy. This important book enhances understanding of entrepreneurial dynamics, providing the first analysis of changes in US entrepreneurial activity. Based on the unprecedented Panel Study of Entrepreneurial Dynamics, it examines adult participation in new firm creation and differences in regional firm creation activity. Shedding light on the importance of new firms for job growth, productivity enhancements, innovation, and routes for social mobility, the author tracks the success or failure of entrepreneurs, including comparisons of different groups, such as women and minorities, along with different countries. All sectors of the population are making significant contributions. Significant implications for practitioners, educators and policy makers are discussed.

Buch. Condizione: Neu. Neuware -Humans suffer from numerous parasitic foodborne zoonoses, many of which are caused by helminths. The helminth zoonoses of concern in this book are normally limited to diseases of animals which have now become transmissible to humans. In the past these diseases were limited to populations living in low- and middle-income countries, but the geographical limits and populations at risk are expanding and changing because of growing international markets , improved transportation systems, and demographic changes (such as population movements). The World Health Organization (WHO) has estimated that the number of people currently infected with food borne trematodes alone exceeds 41 million, but worldwide the number of people at risk, including those in developed countries, is 750 million. The increasing recognition of the public health significance of these zoonoses, especially their complicated epidemiologies, and their links to poverty, intensification of agriculture, environmental degradation, and lack of tools for control- has been welcome. However, the development of priorities for a national public health system is often a competitive exercise, and the argument for devoting appropriate attention and resources to foodborne parasitic zoonoses is generally handicapped by the lack of good health and economic impact data. The genesis of this book was a desire to draw attention to the problem of these zoonoses and to hopefully, inspire greater efforts to acquire a reliable global impact assessment and therefore a basis for improved prevention and control actions for these zoonoses.This book reviews not only the prevalence and distribution of these zoonoses, including available health and economic impact data, but will highlight gaps in knowledge that must be filled in order to gain the assessment needed to depict the overall importance of a particular zoonosis. This is critical for comparisons to other pressing public health and development needs in resource allocations. The topics on epidemiology, diagnosis, and clinical aspects emphasize the knowledge gaps that limit a full understanding of these zoonoses, and target where greater research investments on these parasitic diseases should be focused.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 448 pp. Englisch.

Buch. Condizione: Neu. Neuware -At the present time, the laboratory mouse has become a central tool for skeletal studies, mainly because of the extensive use of genetic manipulations in this species. Naturally, this widespread use of mice in developmental, bone, joint, tooth, and neurological research calls for detailed anatomical knowledge of the mouse skeleton as a reference for experimental design and phenotyping under a variety of experimental conditions, including genetic manipulations (e.g., transgenic and kno- out mice). Several general treatises on the normal anatomy of the mouse and rat have been published in the previous century. In the absence of adequate technologies, these books describe only the external anatomical features of the different parts of the skeleton. In general, images in these atlases are camera lucida-based line drawings rather than accurate three-dimensional images. Furthermore, so far a systematic two- and three-dimensional description of the internal anatomy of bones, as well as the three-dimensional relationship exhibited in joints, are not available.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch.

Buch. Condizione: Neu. Neuware - Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been new developments in this field including the publication of three whole genome sequences, the discovery of a developmental cycle and novel cyst-like highly infectious form, and the bacteria have been used as a probe for macrophage cellular function to unravel fundamental new knowledge in the area of cellular biology. Legionella has also become a model system for the study of innate as well as adaptive immunity. Information on Legionella continues to increase in the U.S. and abroad. Columbia University has started the first Legionella Genome Project with a multi-million dollar grant from the NIH. In addition, The European Working Group for Legionella infections was formed in 1986. Members are scientists with an interest in improving knowledge and information on the clinical and environmental aspects of legionnaires' disease through developments in diagnosis, management and treatment of the disease. The volume brings together all of the lastest research on this pathogen, the interest in which is rapidly growing.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The competitive environment is becoming increasingly more complex and intense. In order to cope, business decisions related to various areas tend to become more interrelated. Firms need to couple their operations strategies to the marketing strategies to best support the competition of their products in the marketplace. The perspectives on production management systems are getting more strategic. A more integrated approach is thus called for, bringing together the various perspectives on production management systems and operations strategy. This relationship is important in any type of operation, perhaps more so in supply chains, production networks and global operations. This book brings together the latest thinking by leading experts, analysts, academics, researchers, and industrial practitioners from around the world who have worked extensively in the area of production management systems and strategies. In the individual chapters of this book, authors put forward their perspectives, approaches, and tools for use in developing and integrating systems and strategies in production management. 422 pp. Englisch.