9780387337845 - the biology of dendritic cells and hiv infection (20 risultati)
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Condizione: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if t…he Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.
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Da: Buchpark, Trebbin, GermaniaBuchpark
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Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 576 | Sprache: Englisch | Produktart: Bücher | Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms…underlying the pathogenesis of viral diseases as well as for the progress on the development of prophylactic and therapeutic vaccines. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in virus spreading to T cells. Interestingly, HIV can exploit many of the cellular processes responsible for the generation and regulation of the adaptive immune responses to gain access to its main target cells, i.e. the CD4+ T lymphocytes. Thus, the central role of DCs in stimulating T cell activation not only provides a route for viral transmission, but also represents a vulnerable point at which HIV-1 can interfere with the initiation of primary T cell immunity. Recent studies have revealed that several HIV proteins can profoundly influence the phenotype and functions of DCs even in the absence of a productive infection, often resulting in an abnormal immune response. While this knowledge has resulted in the identification of some major mechanisms involved in the pathogenesis of HIV-1 infection, the recent progress on DC biology has opened perspectives in the research on new adjuvants (selectively acting on DCs) and on novel strategies for the in vivo targeting of antigens to DCs, which appear to be highly relevant for the development of HIV vaccines. Of note, defects in the number and functions of DCs have been observed in the course of HIV infection and during disease progression, thus suggesting that DCs play an important role in the immune control of viral replication and virus-induced dysfunctions. The development of therapeutic vaccination strategies to be combined with HAART is thought as an important step for an effective control of HIV infection in patients. In this context, the use of autologous DCs may represent an attracting strategy. Notably, DCs are now regarded as a valuable approach for the development of cancer vaccines and several clinical trials have explored the efficacy of different DC preparations as cellular adjuvants in inducing a potentially protective immune response. Recent data in animal models provide the background for the clinical testing of DC-based vaccines in HIV-1-infected patients. Now that we start to understand the complex interactions between HIV and DCs in the pathogenesis of AIDS and we are learning how to prepare potentially effective DCs from lessons on cancer vaccines, we may reasonably assume that DC-based therapeutic vaccines can represent a topic of increasing interest in protocols of clinical immunotherapy of HIV-1-infected patients.
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Condizione: New. In.
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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Hardcover. Condizione: Brand New. 1st edition. 544 pages. 9.50x6.50x1.25 inches. In Stock.
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Da: Mispah books, Redhill, SURRE, Regno UnitoMispah books
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Hardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms under…lying the pathogenesis of viral diseases as well as for the progress on the development of prophylactic and therapeutic vaccines. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in virus spreading to T cells. Interestingly, HIV can exploit many of the cellular processes responsible for the generation and regulation of the adaptive immune responses to gain access to its main target cells, i.e. the CD4+ T lymphocytes. Thus, the central role of DCs in stimulating T cell activation not only provides a route for viral transmission, but also represents a vulnerable point at which HIV-1 can interfere with the initiation of primary T cell immunity.Recent studies have revealed that several HIV proteins can profoundly influence the phenotype and functions of DCs even in the absence of a productive infection, often resulting in an abnormal immune response. While this knowledge has resulted in the identification of some major mechanisms involved in the pathogenesis of HIV-1 infection, the recent progress on DC biology has opened perspectives in the research on new adjuvants (selectively acting on DCs) and on novel strategies for the in vivo targeting of antigens to DCs, which appear to be highly relevant for the development of HIV vaccines. Of note, defects in the number and functions of DCs have been observed in the course of HIV infection and during disease progression, thus suggesting that DCs play an important role in the immune control of viral replication and virus-induced dysfunctions. The development of therapeutic vaccination strategies to be combined with HAART is thought as an important step for an effective control of HIV infection in patients. In this context, the use of autologous DCs may represent an attracting strategy. Notably, DCs are now regarded as a valuable approach for the development of cancer vaccines and several clinical trials have explored the efficacy of different DC preparations as cellular adjuvants in inducing a potentially protective immune response. Recent data in animal models provide the background for the clinical testing of DC-based vaccines in HIV-1-infected patients. Now that we start to understand the complex interactions between HIV and DCs in the pathogenesis of AIDS and we are learning how to prepare potentially effective DCs from lessons on cancer vaccines, we may reasonably assume that DC-based therapeutic vaccines can represent a topic of increasing interest in protocols of clinical immunotherapy of HIV-1-infected patients. 576 pp. Englisch.
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Da: moluna, Greven, Germaniamoluna
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EUR 136,16
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The only comprehensive volume on pathogenesis and immunity of Dendritic Cells that also focuses on HIVDendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among m…any other viruses. Research on dendritic cel.
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Da: preigu, Osnabrück, Germaniapreigu
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Buch. Condizione: Neu. The Biology of Dendritic Cells and HIV Infection | Filippo Belardelli (u. a.) | Buch | xxv | Englisch | 2007 | Copernicus | EAN 9780387337845 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on…Demand.
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 176,33
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Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying… the pathogenesis of viral diseases as well as for the progress on the development of prophylactic and therapeutic vaccines. This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in virus spreading to T cells. Interestingly, HIV can exploit many of the cellular processes responsible for the generation and regulation of the adaptive immune responses to gain access to its main target cells, i.e. the CD4+ T lymphocytes. Thus, the central role of DCs in stimulating T cell activation not only provides a route for viral transmission, but also represents a vulnerable point at which HIV-1 can interfere with the initiation of primary T cell immunity.Recent studies have revealed that several HIV proteins can profoundly influence the phenotype and functions of DCs even in the absence of a productive infection, often resulting in an abnormal immune response. While this knowledge has resulted in the identification of some major mechanisms involved in the pathogenesis of HIV-1 infection, the recent progress on DC biology has opened perspectives in the research on new adjuvants (selectively acting on DCs) and on novel strategies for the in vivo targeting of antigens to DCs, which appear to be highly relevant for the development of HIV vaccines. Of note, defects in the number and functions of DCs have been observed in the course of HIV infection and during disease progression, thus suggesting that DCs play an important role in the immune control of viral replication and virus-induced dysfunctions. The development of therapeutic vaccination strategies to be combined with HAART is thought as an important step for an effective control of HIV infection in patients. In this context, the use of autologous DCs may represent an attracting strategy. Notably, DCs are now regarded as a valuable approach for the development of cancer vaccines and several clinical trials have explored the efficacy of different DC preparations as cellular adjuvants in inducing a potentially protective immune response. Recent data in animal models provide the background for the clinical testing of DC-based vaccines in HIV-1-infected patients. Now that we start to understand the complex interactions between HIV and DCs in the pathogenesis of AIDS and we are learning how to prepare potentially effective DCs from lessons on cancer vaccines, we may reasonably assume that DC-based therapeutic vaccines can represent a topic of increasing interest in protocols of clinical immunotherapy of HIV-1-infected patients.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 160,49
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlyin…g the pathogenesis of viral diseases as well as for the progress on the development of prophylactic and therapeutic vaccines.This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in virus spreading to T cells. Interestingly, HIV can exploit many of the cellular processes responsible for the generation and regulation of the adaptive immune responses to gain access to its main target cells, i.e. the CD4+ T lymphocytes. Thus, the central role of DCs in stimulating T cell activation not only provides a route for viral transmission, but also represents a vulnerable point at which HIV-1 can interfere with the initiation of primary T cell immunity.Recent studies have revealed that several HIV proteins can profoundly influence the phenotype and functions of DCs even in the absence of a productive infection, often resulting in an abnormal immune response. While this knowledge has resulted in the identification of some major mechanisms involved in the pathogenesis of HIV-1 infection, the recent progress on DC biology has opened perspectives in the research on new adjuvants (selectively acting on DCs) and on novel strategies for the in vivo targeting of antigens to DCs, which appear to be highly relevant for the development of HIV vaccines. Of note, defects in the number and functions of DCs have been observed in the course of HIV infection and during disease progression, thus suggesting that DCs play an important role in the immune control of viral replication and virus-induced dysfunctions. The development of therapeutic vaccination strategies to be combined with HAART is thought as an important step for an effective control of HIV infection in patients. In this context, the use of autologous DCs may represent an attracting strategy. Notably, DCs are now regarded as a valuable approach for the development of cancer vaccines and several clinical trials have explored the efficacy of different DC preparations as cellular adjuvants in inducing a potentially protective immune response. Recent data in animal models provide the background for the clinical testing of DC-based vaccines in HIV-1-infected patients. Now that we start to understand the complex interactions between HIV and DCs in the pathogenesis of AIDS and we are learning how to prepare potentially effective DCs from lessons on cancer vaccines, we may reasonably assume that DC-based therapeutic vaccines can represent a topic of increasing interest in protocols of clinical immunotherapy of HIV-1-infected patients.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 576 pp. Englisch.
