Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
Da: Ria Christie Collections, Uxbridge, Regno Unito
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Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
Da: Buchpark, Trebbin, Germania
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Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Abstract:The purpose of this study was to understand the control of synthesis of Tdt at a molecular level, using a murine pre B-cell line inducible for the enzyme. FLEl-4, an Abelson virus transformed fetal liver cell line, when treated with dibutyryl cAMP and caffeine (or other phosphodiesterase inhibitors), shows a three- to tenfold induction of Tdt, as measured by immunoprecipitation of pulse labelled enzyme, activity assays, and steady-state northern blot. The study also revealed Tdt expression (mRNA induction) by a group of agents which inhibit DNA synthesis by various mechanisms. This finding implies that Tdt expression is unlinked to clonal proliferation of pre-B cells, and suggests a multistage model for B-cell differentiation and the generation of immunoglobulin somatic variation. At a molecular level, the agents that induce Tdt were also shown to increase intracellular cAMP levels shortly before Tdt transcription. Finally, an analysis of histone phosphorylation patterns in induced cells reveal a marked enhancement of histone HI phosphorylation, a finding which may be related to the induction event. Dissertation Discovery Company and the University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line" by Randy Jonathan Horwitz, was obtained from the University of Florida and is being sold with permission from the author. A free digital copy of this work may also be found in the university's institutional repository, the IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
Da: Mispah books, Redhill, SURRE, Regno Unito
EUR 197,95
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Aggiungi al carrelloHardcover. Condizione: New. NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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Aggiungi al carrelloHRD. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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Aggiungi al carrelloHRD. Condizione: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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EUR 107,00
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Aggiungi al carrelloHardback. Condizione: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
Da: Majestic Books, Hounslow, Regno Unito
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Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
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Aggiungi al carrelloBuch. Condizione: Neu. The Regulation of Expression of Terminal Deoxynucleotidyl Transferase in an Inducible Murine Pre-B Cell Line | Randy Horwitz | Buch | Gebunden | Englisch | 2019 | Dissertation Discovery Company | EAN 9780530018591 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.
Lingua: Inglese
Editore: Dissertation Discovery Company, 2019
ISBN 10: 0530018594 ISBN 13: 9780530018591
Da: AHA-BUCH GmbH, Einbeck, Germania
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