9781334417900 - the coagulation of blood: dissertation submitted to the board of university studies of the johns hopkins university in conformity with the ... of doctor of philosophy (classic reprint) di rettger, louis john (3 risultati)

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Paperback. Condizione: New. Print on Demand. This book delves into the intricate mechanisms of blood coagulation, a crucial process in maintaining the integrity of the circulatory system. It begins by examining the historical understanding of coagulation, from Schmidt's early work to contemporary models involving multiple factor…s. The author meticulously dissects each factor, including fibrinogen, thrombin, and calcium, providing a comprehensive analysis of their roles in the coagulation cascade. Detailed experiments reveal the precise conditions under which thrombin exerts its action, as well as its stability and response to heat and pH changes. The book further investigates the enigmatic source of thrombin, exploring the theories of proferment activation and the involvement of formed blood elements. It also examines the potential role of tissue extracts and anti-thrombins, shedding light on their influence on coagulation dynamics. Ultimately, this book offers a refined and nuanced understanding of the complex interactions that orchestrate blood clotting, highlighting the delicate balance that ensures both hemostasis and the prevention of unwanted clots. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.