9781468468397 - inducible gene expression, volume 2: hormonal signals (16 risultati)
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Condizione: New. 2012. Softcover reprint of the original 1st ed. 1995. paperback. . . . . .
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Condizione: New. 2012. Softcover reprint of the original 1st ed. 1995. paperback. . . . . . Books ship from the US and Ireland.
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Taschenbuch. Condizione: Neu. Inducible Gene Expression, Volume 2 | Hormonal Signals | P. A. Baeuerle | Taschenbuch | Progress in Gene Expression | 284 S. | Englisch | 2012 | Birkhäuser | EAN 9781468468397 | Verantwortliche Person für die EU: Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Ber…lin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Cells have evolved multiple strategies to adapt the composItIon and quality of their protein equipment to needs imposed by changing conditions within the organism. Extracellular stimuli that inform cells about such needs are hormones, cytokines an…d neurotransmitters, which bind to specific cell surface receptors. Inside the cell, secondary signals are then produced which, ultimately, initiate the expression of proteins giving novel functional properties to the stimulated cells. This process can be controlled at a transcriptional, posttranscriptional, translational or posttranslational level. Extensive research over the past fifteen years has shown that transcriptional regulation is probably the most impor tant strategy used to control the production of new proteins in response to hormonal signals. At the level of gene transcription, the initiation of mRNA synthesis is most frequently used to govern gene expression. The key elements controlling transcription initiation in eukaryotes are acti vator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the proximity of genes. The activator binding sites are elements oflarger control units, called promoters and enhancers, which bind many distinct proteins that may synergize or negatively cooperative with the activators. The de novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. In this second volume of Inducible Gene Expression, leading scientists in the field review eight eukaryotic transactivators that allow cells to respond to hormonal stimuli by the expression of new proteins.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cells have evolved multiple strategies to adapt the composItIon and quality of their protein equipment to needs imposed by changing conditions within the organism. Extracellular stimuli that inform cells about such needs are hormon…es, cytokines and neurotransmitters, which bind to specific cell surface receptors. Inside the cell, secondary signals are then produced which, ultimately, initiate the expression of proteins giving novel functional properties to the stimulated cells. This process can be controlled at a transcriptional, posttranscriptional, translational or posttranslational level. Extensive research over the past fifteen years has shown that transcriptional regulation is probably the most impor tant strategy used to control the production of new proteins in response to hormonal signals. At the level of gene transcription, the initiation of mRNA synthesis is most frequently used to govern gene expression. The key elements controlling transcription initiation in eukaryotes are acti vator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the proximity of genes. The activator binding sites are elements oflarger control units, called promoters and enhancers, which bind many distinct proteins that may synergize or negatively cooperative with the activators. The de novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a high-level expression of genes. In this second volume of Inducible Gene Expression, leading scientists in the field review eight eukaryotic transactivators that allow cells to respond to hormonal stimuli by the expression of new proteins. 300 pp. Englisch.
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Condizione: New. Print on Demand pp. 300 49:B&W 6.14 x 9.21 in or 234 x 156 mm (Royal 8vo) Perfect Bound on White w/Gloss Lam.
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. 1 CREM, a Master-Switch in the Nuclear Response to cAMP Signaling.- 2 Signal Uptake by the c-fos Serum Response Element.- 3 DRTF1/E2F: A Molecular Switch in Cell Cycle Control.- 4 Direct Signal Transduction by Tyrosi…ne Phosphorylation of Transcription Facto.
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -1 CREM, a Master-Switch in the Nuclear Response to cAMP Signaling.- 2 Signal Uptake by the c-fos Serum Response Element.- 3 DRTF1/E2F: A Molecular Switch in Cell Cycle Control.- 4 Direct Signal Transduction by Tyrosine Phosphorylation…of Transcription Factors with SH2 Domains.- 5 The Glucocorticoid Hormone Receptor.- 6 Thyroid Hormone Receptors.- 7 Retinoic Acid Receptors.- 8 Regulation of Nuclear Transport and Activity of the Drosophila Morphogen Dorsal.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 300 pp. Englisch.
