9781493937356 - thyroid hormone disruption and neurodevelopment (12 risultati)
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
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Da: Midtown Scholar Bookstore, Harrisburg, PA, U.S.A.Midtown Scholar Bookstore
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hardcover. Condizione: Very Good. No dust jacket as issued. No dust jacket. Very Good hardcover with light shelfwear - NICE! Standard-sized.
Lingua: Inglese
Editore: Springer New York 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
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Da: Buchpark, Trebbin, GermaniaBuchpark
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Condizione: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However…, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a ¿repressor¿ of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ¿.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Condizione: New. In.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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Condizione: New. pp. 260.
Lingua: Inglese
Editore: Springer New York, Springer US 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the m…olecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first bookto comprehensively describethe effect of thyroid hormone disruptionin the central nervous system.The first section deals with the disruption of thyroid hormone action at themolecular level. Firstthe authorsprovide a summary ofthe possible molecular mechanisms of thyroid hormone action in the brain, thenthey discussseveral factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanismsthat createeach abnormal phenotype are not fully understood.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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Hardcover. Condizione: Brand New. 9.50x6.25x0.75 inches. In Stock.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
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Da: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
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Condizione: new. Questo è un articolo print on demand.
Lingua: Inglese
Editore: Springer New York 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
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Da: moluna, Greven, Germaniamoluna
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The first book to describe the effects of thyroid hormone disruptions on neurodevelopmentProvides perspectives from molecular studies, animal studies, and human studies Suitable for both basic researche…rs and clinici.
Lingua: Inglese
Editore: Springer New York Nov 2016 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans…. However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first bookto comprehensively describethe effect of thyroid hormone disruptionin the central nervous system.The first section deals with the disruption of thyroid hormone action at themolecular level. Firstthe authorsprovide a summary ofthe possible molecular mechanisms of thyroid hormone action in the brain, thenthey discussseveral factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanismsthat createeach abnormal phenotype are not fully understood. 220 pp. Englisch.
Lingua: Inglese
Editore: Springer, Springer US Nov 2016 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
- Print on Demand
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. Ho…wever, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a 'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ¿Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 220 pp. Englisch.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
- Print on Demand
Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
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Condizione: New. Print on Demand pp. 260.
Lingua: Inglese
Editore: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 di 20. Libro 13 di 20 - Contemporary Clinical Neuroscience
- Rilegato
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Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios
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Condizione: New. PRINT ON DEMAND pp. 260.
