9783030887216 - formulating poorly water soluble drugs: 50 (9 risultati)

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Lingua: Inglese
Editore: Springer, Berlin|Springer International Publishing|American Association of Pharmaceutical Scientists|Springer, 2023
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Taschenbuch. Condizione: Neu. Formulating Poorly Water Soluble Drugs | Robert O. Williams Iii (u. a.) | Taschenbuch | AAPS Advances in the Pharmaceutical Sciences Series | xii | Englisch | 2023 | Springer | EAN 9783030887216 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[d…ot]hartmann[at]springer[dot]com | Anbieter: preigu.

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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The objective of thisthird editionis to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scie…ntist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess ataminimum a working knowledge of each of theabove mentionedfacetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Formulating Poorly Water Soluble Drugs
Williams, Robert O., III (Editor)/ Davis, Daniel A., Jr. (Editor)/ Miller, Dave A. (Editor)
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Paperback. Condizione: Brand New. 3rd edition. 705 pages. 10.00x7.01x1.42 inches. In Stock.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The objective of thisthird editionis to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pha…rmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess ataminimum a working knowledge of each of theabove mentionedfacetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop. 708 pp. Englisch.

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs.- Optimizing the Formulation of Poorly Water-Soluble Drugs.- Solid-State Techniques for Improving Solubility.- Mechanical Particle-Size Reduction Techniques.- Co-s…olvent and Complexation Systems.- Injectable Formulations of Poorly Water-Soluble Drugs.- Lipid-Based Formulations.- Structured Development Approach for Amorphous Systems.- Melt Extrusion.- Spray-Drying Technology.- Pharmaceutical Cryogenic Technologies.- Precipitation Technologies for Nanoparticle Production.- Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs.- Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 708 pp. Englisch.