ISBN: 9783330062665 - grafting of bioactive polymers to create biomimetic surfaces: study of the biological mechanisms from the origin of the observed activity (5 risultati)

Paperback. Condizione: Brand New. 192 pages. 8.66x5.91x0.44 inches. In Stock.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The use of the titanium (including the alloy Ti6Al4V) in the biomedical field is not new. In fact, it has been extensively used for more than 50 years. Still, in its ordinary form, titanium-based materials can slowly induce the formation of a fibrous layer, even after several years of implantation, compromising the interface with the living tissue and leading to the progressive loss of osteointegration. The inability of titanium to establish strong chemical bonds with the biological material is at the origin of such problems. We proposed the functionalization of the alloy Ti6Al4V with bioactive polymers, namely poly(sodium styrene sulfonate), by chemical grafting to overcome these issues. MC3T3-E1 osteoblast-like cells were culture on these biofunctionalized surfaces and their response, in the presence and absence of important adhesive proteins, was followed both in vitro and in vivo. With this approach we intended to accommodate, at the surface of the biomaterial, the chemical and protein bases required to achieve a 'perfect' control of the cell behavior at the interface, without inducing a cytotoxic response. 192 pp. Englisch.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: P. Felgueiras HelenaDr. Felgueiras graduated in Biomedical Engineering and has a Master degree in Biomaterials, Biomechanics and Rehabilitation, both from University of Minho, Portugal. In 2014, she concluded her PhD work, also in th.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The use of the titanium (including the alloy Ti6Al4V) in the biomedical field is not new. In fact, it has been extensively used for more than 50 years. Still, in its ordinary form, titanium-based materials can slowly induce the formation of a fibrous layer, even after several years of implantation, compromising the interface with the living tissue and leading to the progressive loss of osteointegration. The inability of titanium to establish strong chemical bonds with the biological material is at the origin of such problems. We proposed the functionalization of the alloy Ti6Al4V with bioactive polymers, namely poly(sodium styrene sulfonate), by chemical grafting to overcome these issues. MC3T3-E1 osteoblast-like cells were culture on these biofunctionalized surfaces and their response, in the presence and absence of important adhesive proteins, was followed both in vitro and in vivo. With this approach we intended to accommodate, at the surface of the biomaterial, the chemical and protein bases required to achieve a 'perfect' control of the cell behavior at the interface, without inducing a cytotoxic response.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The use of the titanium (including the alloy Ti6Al4V) in the biomedical field is not new. In fact, it has been extensively used for more than 50 years. Still, in its ordinary form, titanium-based materials can slowly induce the formation of a fibrous layer, even after several years of implantation, compromising the interface with the living tissue and leading to the progressive loss of osteointegration. The inability of titanium to establish strong chemical bonds with the biological material is at the origin of such problems. We proposed the functionalization of the alloy Ti6Al4V with bioactive polymers, namely poly(sodium styrene sulfonate), by chemical grafting to overcome these issues. MC3T3-E1 osteoblast-like cells were culture on these biofunctionalized surfaces and their response, in the presence and absence of important adhesive proteins, was followed both in vitro and in vivo. With this approach we intended to accommodate, at the surface of the biomaterial, the chemical and protein bases required to achieve a 'perfect' control of the cell behavior at the interface, without inducing a cytotoxic response.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 192 pp. Englisch.…