9783642070518 - cell culture engineering: 101 (8 risultati)

Lingua: Inglese
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Altre immaginiLingua: Inglese
Editore: Springer, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Taschenbuch. Condizione: Neu. Cell Culture Engineering | Wei-Shu Hu | Taschenbuch | Advances in Biochemical Engineering/Biotechnology | xi | Englisch | 2010 | Springer | EAN 9783642070518 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anb…ieter: preigu.

Lingua: Inglese
Editore: Springer, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, wh…ich were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi cations on proteins could only be ef ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.

Lingua: Inglese
Editore: Springer Berlin Heidelberg, 2006
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Paperback. Condizione: Brand New. 168 pages. 9.00x6.00x0.41 inches. In Stock.

Lingua: Inglese
Editore: Springer, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Condizione: new. Questo è un articolo print on demand.

Lingua: Inglese
Editore: Springer Berlin Heidelberg, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Da: moluna, Greven, Germaniamoluna
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Covers trends in modern biotechnologyAll aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering an…d computer science, are treated.

Lingua: Inglese
Editore: Springer Berlin Heidelberg Nov 2010, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic…dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi cations on proteins could only be ef ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade. 180 pp. Englisch.

Lingua: Inglese
Editore: Springer, Springer Spektrum Nov 2010, 2010
Serie: Libro 15 di 81 - Advances in Biochemical Engineering/Biotechnology
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysf…unctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi cations on proteins could only be ef ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 180 pp. Englisch.