ISBN: 9783642205835 - permutation testing for isotonic inference on association studies in genetics (12 risultati)

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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. In this framework we will work out some nonparametric statistical permutation tests and likelihood-based tests to perform case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies, where we deal with several genes and several alleles together. Furthermore, we show simulations under different assumptions on the genetic model and analyse real data sets by simply studying one locus with the permutation test.…

Taschenbuch. Condizione: Neu. Permutation Testing for Isotonic Inference on Association Studies in Genetics | Luigi Salmaso (u. a.) | Taschenbuch | SpringerBriefs in Statistics | vi | Englisch | 2011 | Springer | EAN 9783642205835 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. In this framework we will work out some nonparametric statistical permutation tests and likelihood-based tests to perform case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies, where we deal with several genes and several alleles together. Furthermore, we show simulations under different assumptions on the genetic model and analyse real data sets by simply studying one locus with the permutation test. 80 pp. Englisch.…

Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Multivariate analysis in genetic studies Powerful and flexible statistical solutions Fully nonparametric analysisMultivariate analysis in genetic studies Powerful and flexible statistical solutionsFully nonparametric analysis.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The purpose of this book is to illustrate a new statistical approach to test allelic association and genotype-specific effects in the genetic study of diseases. There are some parametric and non-parametric methods available for this purpose. We deal with population-based association studies, but comparisons with other methods will also be drawn, analysing the advantages and disadvantages of each one, particularly with regard to power properties with small sample sizes. In this framework we will work out some nonparametric statistical permutation tests and likelihood-based tests to perform case-control analyses to study allelic association between marker, disease-gene and environmental factors. Permutation tests, in particular, will be extended to multivariate and more complex studies, where we deal with several genes and several alleles together. Furthermore, we show simulations under different assumptions on the genetic model and analyse real data sets by simply studying one locus with the permutation test.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 80 pp. Englisch.…