9783838346144 - a functional study of notch signaling in brain cancer stem-like cells di kristoffersen, karina (8 risultati)
Lingua: Inglese
Editore: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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Condizione: New. pp. 124.
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Da: preigu, Osnabrück, Germaniapreigu
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Taschenbuch. Condizione: Neu. A Functional Study of Notch Signaling in Brain Cancer Stem-like Cells | Karina Kristoffersen | Taschenbuch | 124 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838346144 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]…de | Anbieter: preigu.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults and confers a dismal prognosis. Despite intense effort, treatment remains a significant therapeutic challenge and new modalities are desp…erately needed. In recent years a population of cancer cells with neural stem cell (NSC)-like properties has been reported in GBM. It is hypothesized that these so- called brain cancer stem-like cells (bCSC) are involved in brain tumor initiation, progression and treatment resistance. The Notch signaling pathway is known to be important in maintaining an undifferentiated pool of normal NSC and in determination of cell fate. Several recent data implicate a functional role for Notch signaling in GBM cells and when considering its role in normal NSC, the Notch signaling pathway might be an appropriate target for bCSC directed GBM therapy. The aim of the present project was to establish and characterize GBM stem-like cell cultures from xenograft tumors originating from human primary GBM, and subsequently investigate the significance of Notch expression and activation in these cultures. 124 pp. Englisch.
Lingua: Inglese
Editore: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
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Condizione: New. Print on Demand pp. 124 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.
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Da: moluna, Greven, Germaniamoluna
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kristoffersen KarinaCurrent position: PhD student. Copenhagen National University Hospital, Denmark. | Education: MSc in Human Biology. University of Copenhagen, Denmark. May 2009. BSc in Biology-Biote…chnology, University of Copen.
Lingua: Inglese
Editore: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios
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Condizione: New. PRINT ON DEMAND pp. 124.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults and confers a dismal prognosis. Despite intense effort, treatment remains a significant therapeutic challenge and new modalities are desperat…ely needed. In recent years a population of cancer cells with neural stem cell (NSC)-like properties has been reported in GBM. It is hypothesized that these so- called brain cancer stem-like cells (bCSC) are involved in brain tumor initiation, progression and treatment resistance. The Notch signaling pathway is known to be important in maintaining an undifferentiated pool of normal NSC and in determination of cell fate. Several recent data implicate a functional role for Notch signaling in GBM cells and when considering its role in normal NSC, the Notch signaling pathway might be an appropriate target for bCSC directed GBM therapy. The aim of the present project was to establish and characterize GBM stem-like cell cultures from xenograft tumors originating from human primary GBM, and subsequently investigate the significance of Notch expression and activation in these cultures.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 124 pp. Englisch.
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 59,00
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults and confers a dismal prognosis. Despite intense effort, treatment remains a significant therapeutic challenge and new modalities are desperate…ly needed. In recent years a population of cancer cells with neural stem cell (NSC)-like properties has been reported in GBM. It is hypothesized that these so- called brain cancer stem-like cells (bCSC) are involved in brain tumor initiation, progression and treatment resistance. The Notch signaling pathway is known to be important in maintaining an undifferentiated pool of normal NSC and in determination of cell fate. Several recent data implicate a functional role for Notch signaling in GBM cells and when considering its role in normal NSC, the Notch signaling pathway might be an appropriate target for bCSC directed GBM therapy. The aim of the present project was to establish and characterize GBM stem-like cell cultures from xenograft tumors originating from human primary GBM, and subsequently investigate the significance of Notch expression and activation in these cultures.
