9783844384161 - functional genetics and psychiatric disorders: an exploration of functional genetic variants in candidate genes for psychiatric disorders di moyer, robert; sadee, wolfgang (6 risultati)
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Taschenbuch. Condizione: Neu. Functional Genetics and Psychiatric Disorders | An Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders | Robert Moyer (u. a.) | Taschenbuch | 96 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783844384161 | Verantwortliche Person für die EU: BoD - B…ooks on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.
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Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Drug addiction is a chronic disorder characterized by compulsive drug seeking and taking despite serious negative consequences. Association studies have identified a number of candidate genes harboring variants associated with susc…eptibility to addiction, but the causative variants frequently remain unknown. A solution to the challenge of identifying causative variants is the thorough characterization of functional genetic polymorphisms and their effects on regulation of candidate genes. I focused on candidate genes for drug addiction (ARRB2, DRD2, and DRD3) and made some novel and significant findings: The effects of two intronic SNPs in the human dopamine receptor D2 (DRD2) gene, previously shown to alter DRD2 alternative splicing, were confirmed in human brain autopsy tissues obtained from a population of cocaine abusers and controls. The same SNPs were significantly associated with cocaine abuse. The results of this study contribute to our understanding of the functional genetic variation in important candidate genes and have the potential to improve the prevention and treatment of drug addiction and other psychiatric disorders. 96 pp. Englisch.
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Da: moluna, Greven, Germaniamoluna
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Moyer RobertDr. Robert Moyer earned his Ph.D. in Molecular Pharmacology, Pharmacogenomics, and Therapeutics from The Ohio State University in 2010. Dr. Wolfgang Sadee is Felts Mercer Professor of Medic…ine and Pharmacology and Chair .
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Drug addiction is a chronic disorder characterized by compulsive drug seeking and taking despite serious negative consequences. Association studies have identified a number of candidate genes harboring variants associated with suscepti…bility to addiction, but the causative variants frequently remain unknown. A solution to the challenge of identifying causative variants is the thorough characterization of functional genetic polymorphisms and their effects on regulation of candidate genes. I focused on candidate genes for drug addiction (ARRB2, DRD2, and DRD3) and made some novel and significant findings: The effects of two intronic SNPs in the human dopamine receptor D2 (DRD2) gene, previously shown to alter DRD2 alternative splicing, were confirmed in human brain autopsy tissues obtained from a population of cocaine abusers and controls. The same SNPs were significantly associated with cocaine abuse. The results of this study contribute to our understanding of the functional genetic variation in important candidate genes and have the potential to improve the prevention and treatment of drug addiction and other psychiatric disorders.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 96 pp. Englisch.
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Drug addiction is a chronic disorder characterized by compulsive drug seeking and taking despite serious negative consequences. Association studies have identified a number of candidate genes harboring variants associated with susceptib…ility to addiction, but the causative variants frequently remain unknown. A solution to the challenge of identifying causative variants is the thorough characterization of functional genetic polymorphisms and their effects on regulation of candidate genes. I focused on candidate genes for drug addiction (ARRB2, DRD2, and DRD3) and made some novel and significant findings: The effects of two intronic SNPs in the human dopamine receptor D2 (DRD2) gene, previously shown to alter DRD2 alternative splicing, were confirmed in human brain autopsy tissues obtained from a population of cocaine abusers and controls. The same SNPs were significantly associated with cocaine abuse. The results of this study contribute to our understanding of the functional genetic variation in important candidate genes and have the potential to improve the prevention and treatment of drug addiction and other psychiatric disorders.
