9798245656649 - timing the dose: the hidden role of biological time in drug absorption, efficacy, and safety di srivastava, dr.ashish; al., et (9 risultati)
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Paperback. Condizione: new. Paperback. Why Do Identical Drug Doses Produce Different Results?Despite precise formulations, standardized clinical trials, and advanced drug delivery systems, pharmaceutical research continues to struggle with unexplained variability in drug response, safety, and effectiveness.What if the missing fa…ctor is not the drug itself-but the timing?Timing the Dose reveals a critical yet overlooked dimension of pharmaceutical science: biological time. This evidence-aware, research-driven book explores how circadian rhythms quietly influence drug absorption, metabolism, efficacy, and toxicity-often without being measured, reported, or formally discussed.What This Book ExplainsThis book translates complex chronobiology into practical pharmaceutical insight, showing how time shapes: Pharmacokinetics and pharmacodynamics across the dayVariability in clinical trial outcomes and bioequivalence dataPerformance of modified-release and controlled-release formulationsDifferences between animal models and human studiesReal-world drug use beyond controlled trial settingsRather than adding complexity, the book demonstrates how time-aware thinking can simplify interpretation, reduce variability, and improve research quality.Who This Book Is ForPharmacy and pharmaceutical science studentsEarly-career researchers and doctoral scholarsFormulation scientists and PK/PD professionalsClinical researchers and trial designersHealthcare professionals interested in drug performance scienceCurious scientific readers seeking deeper insight into how drugs truly workWhat Makes This Book DifferentFocuses on why drugs behave inconsistently, not how to treat diseasesAvoids exaggerated claims and unsupported chronotherapy hypeFrames timing as a scientific context, not a dosing ruleAligns with current regulatory and ethical standardsBridges discovery, formulation, clinical trials, and real-world use into one cohesive frameworkThis is not a clinical guide. It is a thinking guide for modern pharmaceutical science.Why This Topic Matters NowAs drug development costs rise and trial failures persist, understanding hidden variables has become essential. Biological time is one of the most influential-and least discussed-factors shaping drug behavior.Timing the Dose equips readers to see what traditional models overlook.Ideal ForAcademic coursework and self-studyResearch hypothesis developmentFormulation strategy discussionsClinical trial interpretationProfessional pharmaceutical readingIf you want to understand why drugs succeed, fail, or behave unpredictably-without changing the drug itself-this book provides the missing perspective. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Paperback. Condizione: new. Paperback. Why Do Identical Drug Doses Produce Different Results?Despite precise formulations, standardized clinical trials, and advanced drug delivery systems, pharmaceutical research continues to struggle with unexplained variability in drug response, safety, and effectiveness.What if the missing fa…ctor is not the drug itself-but the timing?Timing the Dose reveals a critical yet overlooked dimension of pharmaceutical science: biological time. This evidence-aware, research-driven book explores how circadian rhythms quietly influence drug absorption, metabolism, efficacy, and toxicity-often without being measured, reported, or formally discussed.What This Book ExplainsThis book translates complex chronobiology into practical pharmaceutical insight, showing how time shapes: Pharmacokinetics and pharmacodynamics across the dayVariability in clinical trial outcomes and bioequivalence dataPerformance of modified-release and controlled-release formulationsDifferences between animal models and human studiesReal-world drug use beyond controlled trial settingsRather than adding complexity, the book demonstrates how time-aware thinking can simplify interpretation, reduce variability, and improve research quality.Who This Book Is ForPharmacy and pharmaceutical science studentsEarly-career researchers and doctoral scholarsFormulation scientists and PK/PD professionalsClinical researchers and trial designersHealthcare professionals interested in drug performance scienceCurious scientific readers seeking deeper insight into how drugs truly workWhat Makes This Book DifferentFocuses on why drugs behave inconsistently, not how to treat diseasesAvoids exaggerated claims and unsupported chronotherapy hypeFrames timing as a scientific context, not a dosing ruleAligns with current regulatory and ethical standardsBridges discovery, formulation, clinical trials, and real-world use into one cohesive frameworkThis is not a clinical guide. It is a thinking guide for modern pharmaceutical science.Why This Topic Matters NowAs drug development costs rise and trial failures persist, understanding hidden variables has become essential. Biological time is one of the most influential-and least discussed-factors shaping drug behavior.Timing the Dose equips readers to see what traditional models overlook.Ideal ForAcademic coursework and self-studyResearch hypothesis developmentFormulation strategy discussionsClinical trial interpretationProfessional pharmaceutical readingIf you want to understand why drugs succeed, fail, or behave unpredictably-without changing the drug itself-this book provides the missing perspective. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
