Condizione: Good. The book is nice and 100% readable, but the book has visible wear which may include stains, scuffs, scratches, folded edges, sticker glue, highlighting, notes, and worn corners.
Hardcover. Condizione: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.
Hardcover. Condizione: Very Good. No Jacket. May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.
Condizione: As New. Like New condition. A near perfect copy that may have very minor cosmetic defects. NOT AVAILABLE FOR SHIPMENT OUTSIDE OF THE UNITED STATES.
hardcover. Condizione: new.
Condizione: New.
Da: Chiron Media, Wallingford, Regno Unito
EUR 158,72
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Aggiungi al carrelloHardcover. Condizione: New.
Condizione: As New. Unread book in perfect condition.
Da: Revaluation Books, Exeter, Regno Unito
EUR 183,11
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Aggiungi al carrelloHardcover. Condizione: Brand New. 2nd edition. 468 pages. 9.13x6.57x1.11 inches. In Stock.
Da: Best Price, Torrance, CA, U.S.A.
Condizione: New. SUPER FAST SHIPPING.
Da: Ria Christie Collections, Uxbridge, Regno Unito
EUR 211,35
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Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 211,34
Quantità: 6 disponibili
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Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 241,55
Quantità: 6 disponibili
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EUR 234,97
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Editore: Elsevier Science Publishing Co Inc Feb 2016, 2016
ISBN 10: 0128010762 ISBN 13: 9780128010761
Lingua: Inglese
Da: AHA-BUCH GmbH, Einbeck, Germania
EUR 291,71
Quantità: 2 disponibili
Aggiungi al carrelloBuch. Condizione: Neu. Neuware - Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Review chapters provide context and underscore the importance of key concepts such as pharmacokinetics, toxicity, the blood-brain barrier, diagnosing drug limitations, prodrugs, and formulation. Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization.